Alexander C. Huang

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 46 papers. Top paper: “Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications”.

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

Science(2020)10.1126/science.abc8511

N/A

14.5DataRank · unranked

1659 citations

Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Allison R. Greenplate, Jennifer E. Wu +50 more

Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

Cancer Research Communications(2023)10.1158/2767-9764.crc-22-0486

N/A

2.2DataRank · unranked

95 citations

Alexander C. Huang, Xiaowei Xu, Robert Orlowski, Ravi K. Amaravadi, Lynn M. Schuchter +20 more

A decade of checkpoint blockade immunotherapy in melanoma: understanding the molecular basis for immune sensitivity and resistance

Nature Immunology(2022)10.1038/s41590-022-01141-1

N/A

0.957DataRank · unranked

588 citations

Roberta Zappasodi, Alexander C. Huang

Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19

Science Immunology(2021)10.1126/sciimmunol.abf7570

N/A

0.800DataRank · unranked

206 citations

Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Caroline Diorio, Leticia Kuri-Cervantes +59 more

Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapy

Nature Communications(2021)10.1038/s41467-020-20600-7

N/A

0.784DataRank · unranked

185 citations

Thomas Connelly, Robin Choi, Hyeree Choi, Anastasia Samarkina, Ling Li +52 more

Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells

Cell Reports(2021)10.1016/j.celrep.2021.109120

N/A

0.724DataRank · unranked

124 citations

Shin Foong Ngiow, Zeyu Chen, John Attanasio, Sasikanth Manne, Gordon Ruthel +13 more

Patient-derived melanoma organoid models facilitate the assessment of immunotherapies

EBioMedicine(2023)10.1016/j.ebiom.2023.104614

N/A

0.675DataRank · unranked

89 citations

Shujing Liu, Huaishan Wang, Yeye Guo, Lei Guan, Longbin Shen +18 more

Costimulation of γδTCR and TLR7/8 promotes Vδ2 T-cell antitumor activity by modulating mTOR pathway and APC function

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-003339

N/A

0.524DataRank · unranked

32 citations

Hui Chen, Shujing Liu, Jie Zhang, Hezhe Lu, Rajasekharan Somasundaram +19 more

Phase I trial of autologous cMET-directed CAR-t cells administered intravenously in patients with melanoma & breast carcinoma.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.10035

N/A

0.470DataRank · unranked

22 citations

Alexander C. Huang, Xiaowei Xu, Paul J. Zhang, Robert Orlowski, Tina Matlawski +15 more

SARS-CoV-2 Seropositivity and Seroconversion in Patients Undergoing Active Cancer-Directed Therapy

JCO Oncology Practice(2021)10.1200/op.21.00113

N/A

0.373DataRank · unranked

3 citations

Sanjna Surya, Noah G. Goodman, Anh N. Le, Gregory Kelly, Olutosin Owoyemi +37 more

Neoadjuvant-adjuvant pembrolizumab in clinical stage IIB/C melanoma.

Journal of Clinical Oncology(2025)10.1200/jco.2025.43.16_suppl.9502

N/A

0.345DataRank · unranked

9 citations

Mohammad Saad Farooq, Phyllis A. Gimotty, Tara C. Mitchell, Ravi K. Amaravadi, Lynn M. Schuchter +11 more

Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.16.488552

N/A

0.269DataRank · unranked

5 citations

Sasikanth Manne, Nils Wellhausen, Derek A. Oldridge, Allison R. Greenplate, Lakshmi Chilukuri +10 more

High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline

STAR Protocols(2023)10.1016/j.xpro.2023.102289

N/A

0.241DataRank · unranked

4 citations

Olga Lyudovyk, Justin Kim, Ya-Hui Lin, Yuval Elhanati, Divij Mathew +7 more

Final results of a phase I “RadVax” trial of hypofractionated radiation combined with pembrolizumab in patients with metastatic solid tumors.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.2576

N/A

0.241DataRank · unranked

4 citations

Rosemarie Mick, Alexander C. Huang, Nicholas Han, Michael D. Farwell, Tara C. Mitchell +11 more

The validity of a machine learning algorithm in predicting response to immune checkpoint inhibitors in melanoma.

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.16_suppl.9523

N/A

0.104DataRank · unranked

1 citations

Nicolas Coudray, George Jour, Clara Goldberg, Paul Johannet, Alexander C. Huang +6 more

SARS-CoV-2 seropositivity and seroconversion in patients undergoing active cancer-directed therapy

medRxiv(2021)10.1101/2021.01.15.21249810

N/A

0.104DataRank · unranked

1 citations

Sanjna Surya, Noah Goodman, Anh N. Le, Greg Kelly, Olutosin Owoyemi +37 more

Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.03.509766

N/A

0DataRank · unranked

14 citations

Mohamed S. Abdel-Hakeem, Sasikanth Manne, Zhen Zhang, Hua Huang, Makoto Kurachi +15 more

Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure

Immunity(2023)10.1016/j.immuni.2023.11.005

N/A

0DataRank · unranked

132 citations

Mohamed S. Abdel-Hakeem, Sasikanth Manne, Zhen Zhang, Hua Huang, Makoto Kurachi +16 more

Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

Nature Immunology(2023)10.1038/s41590-023-01613-y

N/A

0DataRank · unranked

109 citations

Timothy S. Johnston, Kendall A. Lundgreen, Jefferson Santos, Juliana S. Qin, Rishi Raj Goel +55 more

Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.05.527215

N/A

0DataRank · unranked

8 citations

Timothy S. Johnston, Kendall A. Lundgreen, Jefferson Santos, Juliana S. Qin, Rishi Raj Goel +32 more

Data from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T cells Administered Intravenously in Patients with Melanoma & Breast Carcinoma

(2023)10.1158/2767-9764.c.6547846.v1

N/A

0DataRank · unranked

0 citations

Alexander C. Huang, Xiaowei Xu, Robert Orlowski, Ravi K. Amaravadi, Lynn M. Schuchter +20 more

Data from Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma

(2023)10.1158/2767-9764.c.6547846.v2

N/A

0DataRank · unranked

0 citations

Alexander C. Huang, Xiaowei Xu, Robert Orlowski, Ravi K. Amaravadi, Lynn M. Schuchter +20 more

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells

Cancer Cell(2024)10.1016/j.ccell.2024.08.007

N/A

0DataRank · unranked

102 citations

Paulina Coutifaris, David Brocks, Guanning Wang, Tarek Azar, Sabrina Solis +33 more

LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity

Cell(2024)10.1016/j.cell.2024.07.018

N/A

0DataRank · unranked

100 citations

Sasikanth Manne, Yinghui Huang, Tarek Azar, Zeyu Chen, Divij Mathew +15 more

FDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-2390

N/A

0DataRank · unranked

16 citations

Bryan H. Chang, Alexander C. Huang, Xiaowei Xu, Daniel Yoon, Catherine G. Shang +11 more

Tumor-Infiltrating Lymphocytes in Necrotic Tumors after Melanoma Neoadjuvant Anti–PD-1 Therapy Correlate with Pathologic Response and Recurrence-Free Survival

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-23-3775

N/A

0DataRank · unranked

10 citations

Tara C. Mitchell, Meaghan Dougher, Cimarron E. Sharon, Gabriella N. Tortorello, David E. Elder +10 more

Antigen-specific profiling for neoadjuvant anti-PD-1 therapy in melanoma.

Journal of Clinical Oncology(2024)10.1200/jco.2024.42.16_suppl.9576

N/A

0DataRank · unranked

0 citations

Guanning Wang, Ajeya Nandi, Justin Kim, Aaron Nickie, Stella Park +10 more

Antigen-specific profiling identifies T-bet+ melanoma-specific CD8+ T cells associated with response to neoadjuvant PD-1 blockade

Cancer Cell(2025)10.1016/j.ccell.2025.12.004

N/A

0DataRank · unranked

3 citations

Daniel Yoon, Ajeya Nandi, Khushboo Patel, Tarek Azar, Justin Kim +25 more

DR5 CAR-T cells target melanoma and suppress MDSCs with minimal toxicity

Molecular Therapy(2025)10.1016/j.ymthe.2025.12.025

N/A

0DataRank · unranked

1 citations

Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo +19 more

Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8 + T cells underlies distinct functional potential

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.08.669213

N/A

0DataRank · unranked

1 citations

Mark M. Painter, Sasikanth Manne, Víctor Alcalde, M. A. McLaughlin, Matthew Sullivan +28 more

DR5 CAR-T cells target solid tumors and suppress MDSCs with minimal toxicity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.09.658618

N/A

0DataRank · unranked

0 citations

Shujing Liu, Prithvi Sinha, Fang Liu, Xiaogang Zhang, Yeye Guo +20 more

Association of Antibiotic Exposure With Survival and Toxicity in Patients With Melanoma Receiving Immunotherapy

JNCI Journal of the National Cancer Institute(2020)10.1093/jnci/djaa057

N/A

0DataRank · unranked

138 citations

Brian Chu, Andrea Facciabene, Kendra Poirier, Xingmei Wang, Abigail Doucette +14 more

Gene signature of antigen processing and presentation machinery predicts response to checkpoint blockade in non-small cell lung cancer (NSCLC) and melanoma

Journal for ImmunoTherapy of Cancer(2020)10.1136/jitc-2020-000974

N/A

0DataRank · unranked

117 citations

Christiana Davis, Charuhas Deshpande, Wei‐Ting Hwang, Seth Jeffries, Alexander C. Huang +4 more

Postvaccination graft dysfunction/aplastic anemia relapse with massive clonal expansion of autologous CD8+ lymphocytes

Blood Advances(2020)10.1182/bloodadvances.2019000853

N/A

0DataRank · unranked

23 citations

Wenzhao Meng, Natasha Stanley, Miren L. Baroja, Chong Xu, Patrick Yan +10 more

Rates of COVID-19–Related Outcomes in Cancer Compared With Noncancer Patients

JNCI Cancer Spectrum(2020)10.1093/jncics/pkaa120

N/A

0DataRank · unranked

45 citations

Sanjna Surya, Anh N. Le, Heena Desai, Abigail Doucette, Peter Gabriel +11 more

Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19

medRxiv(2020)10.1101/2020.09.25.20201863

N/A

0DataRank · unranked

57 citations

Josephine R. Giles, Amy E. Baxter, Derek A. Oldridge, Caroline Diorio, Leticia Kuri-Cervantes +33 more

Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.20.106401

N/A

0DataRank · unranked

115 citations

Josephine R. Giles, Amy E. Baxter, Allison R. Greenplate, Jennifer E. Wu, Cécile Alanio +33 more

Rates of COVID-19-related Outcomes in Cancer compared to non-Cancer Patients

medRxiv(2020)10.1101/2020.08.14.20174961

N/A

0DataRank · unranked

16 citations

Sanjna Surya, Anh N. Le, Heena Desai, Abigail Doucette, Peter Gabriel +11 more

CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

Nature Medicine(2021)10.1038/s41591-021-01386-7

N/A

0DataRank · unranked

520 citations

Nicholas Han, Paul Wileyto, Justin Kim, Sigrid Gouma, James Robinson +55 more

Dichotomous and stable gamma delta T-cell number and function in healthy individuals

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2020-002274

N/A

0DataRank · unranked

27 citations

Huaishan Wang, Qin Liu, Jie Zhang, Hezhe Lu, Liangping Luo +16 more

Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.01.442279

N/A

0DataRank · unranked

13 citations

Amrita Sarkar, H.M. Giannini, Rishi Raj Goel, Divij Mathew, Aae Suzuki +31 more

Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics

Nature Immunology(2022)10.1038/s41590-022-01338-4

N/A

0DataRank · unranked

265 citations

Shin Foong Ngiow, Sasikanth Manne, Amy E. Baxter, Omar Khan, Ping Wang +15 more

PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine

Nature Immunology(2022)10.1038/s41590-022-01274-3

N/A

0DataRank · unranked

79 citations

David A. Knorr, Laura A. Vella, Luisa Victoria Silva, Lakshmi Chilukuri, Sokratis A. Apostolidis +23 more

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19

Frontiers in Immunology(2022)10.3389/fimmu.2022.834988

N/A

0DataRank · unranked

54 citations

Amrita Sarkar, H.M. Giannini, Rishi Raj Goel, Divij Mathew, Aae Suzuki +32 more

Impaired humoral immunity is associated with prolonged COVID-19 despite robust CD8 T cell responses

Cancer Cell(2022)10.1016/j.ccell.2022.05.013

N/A

0DataRank · unranked

46 citations

Justin Kim, David Qualls, Madeline A. Hwee, Ya-Hui Lin, Sawsan R. Boutemine +15 more

Preclinical platforms to study therapeutic efficacy of human γδ T cells

Clinical and Translational Medicine(2022)10.1002/ctm2.814

N/A

0DataRank · unranked

36 citations

Huaishan Wang, Hui Huang, Zhiyan Zhou, Qiang Lin, Yeye Guo +10 more