🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Scott Houliston

University of Toronto

ORCID: 0000-0002-0113-0339

Also affiliated with Princess Margaret Cancer Centre, Structural Genomics Consortium

Biochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

1in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197
Top 100%
0DataRank
Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Papers

Driven by 16 papers — median percentile 0. Top paper: “Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity”.

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00351
N/A
0.292DataRank · unranked
6 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00535
N/A
0.292DataRank · unranked
6 citations

Madhushika Silva, Ayaz Ahmad, Oscar E. A. Arce, Roly J. Armstrong, Cheryl Arrowsmith +105 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq-v3
N/A
0.165DataRank · unranked
2 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq
N/A
0.150DataRank · unranked
1 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

Heat‐induced structural and chemical changes to a computationally designed miniprotein

Protein Science(2024)10.1002/pro.4991
N/A
0DataRank · unranked
7 citations

Sojeong Park, Oliver Cho, Nicholas G. M. Wells, Meagan E. MacDonald, Katerina M. Blejec +11 more

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson’s Disease associated protein

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.18.603797
N/A
0DataRank · unranked
5 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +90 more

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197
Top 100%
0DataRank
Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635
N/A
0DataRank · unranked
9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

Chemical Science(2025)10.1039/d4sc07532c
N/A
0DataRank · unranked
5 citations

Marta Glavatskikh, Xiaowen Wang, Antonio Jesús Lara Ordóñez, Fengling Li, Irene Chau +17 more

Enantioselective protein affinity selection mass spectrometry (E-ASMS)

Nature Communications(2025)10.1038/s41467-025-67403-2
N/A
0DataRank · unranked
1 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +34 more

Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00588
N/A
0DataRank · unranked
1 citations

Evgeny Gutkin, Francesco Gentile, Fuqiang Ban, S. Benjamin Koby, Fengling Li +19 more

Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.17.633682
N/A
0DataRank · unranked
7 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +33 more

An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650479
N/A
0DataRank · unranked
1 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Alternative splicing and allosteric regulation modulate the chromatin binding of UHRF1

Nucleic Acids Research(2020)10.1093/nar/gkaa520
N/A
0DataRank · unranked
19 citations

Sarah Kreuz, Alexander Lemak, Papita Mandal, Zhadyra Yerkesh, Alaguraj Veluchamy +11 more

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c01267
N/A
0DataRank · unranked
26 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +91 more

A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02010
N/A
0DataRank · unranked
22 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +67 more