Charles E. Dann

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 7 papers. Top paper: “Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors”.

Discovery of 6-substituted thieno[2,3-d]pyrimidine analogs as dual inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis in folate receptor expressing human tumors

Bioorganic & Medicinal Chemistry(2021)10.1016/j.bmc.2021.116093

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0DataRank · unranked

12 citations

Nian Tong, Jennifer Wong-Roushar, Carrie O’Connor, Xilin Zhou, Zhanjun Hou +8 more

Structure-Based Design of Transport-Specific Multitargeted One-Carbon Metabolism Inhibitors in Cytosol and Mitochondria

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00763

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0DataRank · unranked

17 citations

Jade M. Katinas, Tejashree Magdum, Khushbu Shah, Jennifer E. Wong, Carrie O’Connor +7 more

Multitargeted 6-Substituted Thieno[2,3-d]pyrimidines as Folate Receptor-Selective Anticancer Agents that Inhibit Cytosolic and Mitochondrial One-Carbon Metabolism

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00020

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0DataRank · unranked

6 citations

Jennifer Wong-Roushar, Adrianne Wallace-Povirk, Yesha V. Shah, Morgan C. Nyman, Jade M. Katinas +10 more

Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0550

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0DataRank · unranked

15 citations

Carrie O’Connor, Aamod S. Dekhne, Xun Bao, Md. Junayed Nayeen, Mathew Schneider +11 more

Role of Mitochondrial and Cytosolic Folylpolyglutamate Synthetase in One-Carbon Metabolism and Antitumor Efficacy of Mitochondrial-Targeted Antifolates

Molecular Pharmacology(2024)10.1124/molpharm.124.000912

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0DataRank · unranked

12 citations

Mathew Schneider, Jade M. Katinas, Md. Junayed Nayeen, Khushbu Shah, Tejashree Magdum +9 more

Structural Characterization of 5-Substituted Pyrrolo[3,2-d]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2

Biochemistry(2024)10.1021/acs.biochem.3c00613

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0DataRank · unranked

6 citations

Md. Junayed Nayeen, Mathew Schneider, Khushbu Shah, Alexandra N. Fifer, Lily M. Klapper +8 more

Pharmacodynamic determinants of mitochondrial one-carbon flux and serine hydroxymethyltransferase inhibition in human tumors

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100120

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0DataRank · unranked

2 citations

Carrie O’Connor, Xun Bao, Md. Junayed Nayeen, Tejashree Magdum, Abhishekh Sharma +7 more