Matthew L. Freedman

Also affiliated with Harvard University, Dana-Farber Cancer Institute, Dana-Farber Brigham Cancer Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 57 papers. Top paper: “Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement”.

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement

Human Genetics(2009)10.1007/s00439-008-0592-7

N/A

11.0DataRank · unranked

188 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

Strengthening the reporting of genetic association studies (STREGA)—an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement

Journal of Clinical Epidemiology(2009)10.1016/j.jclinepi.2008.12.004

N/A

6.0DataRank · unranked

102 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +30 more

Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement

European Journal of Epidemiology(2009)10.1007/s10654-008-9302-y

N/A

4.3DataRank · unranked

65 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

Landscape of prostate-specific membrane antigen heterogeneity and regulation in AR-positive and AR-negative metastatic prostate cancer

Nature Cancer(2023)10.1038/s43018-023-00539-6

N/A

3.3DataRank · unranked

113 citations

Yasutaka Yamada, Sheng-Yu Ku, Varadha Balaji Venkadakrishnan, Joshua A. Korsen, Teja Kalidindi +15 more

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

Nature Communications(2021)10.1038/s41467-021-26042-z

N/A

2.9DataRank · unranked

163 citations

Yingtian Xie, Alba Font‐Tello, Klothilda Lim, Sudeepa Syamala, Xintao Qiu +33 more

STrengthening the REporting of Genetic Association studies (STREGA)—an extension of the STROBE statement

Human Genome Epidemiology, 2nd Edition(2009)10.1093/acprof:oso/9780195398441.003.0010

N/A

1.1DataRank · unranked

7 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +30 more

STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement

PLoS Medicine(2009)10.1371/journal.pmed.1000022

N/A

0.999DataRank · unranked

781 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +31 more

STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statement

Genetic Epidemiology(2009)10.1002/gepi.20410

N/A

0.874DataRank · unranked

339 citations

Julian P. T. Higgins, John P. A. Ioannidis, David Moher, France Gagnon, Erik von Elm +29 more

STrengthening the REporting of Genetic Association studies (STREGA) – an extension of the STROBE statement

European Journal of Clinical Investigation(2009)10.1111/j.1365-2362.2009.02125.x

N/A

0.868DataRank · unranked

326 citations

Julian P.T. Higgins, David Moher, France Gagnon, Erik von Elm, Muin J. Khoury +30 more

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

Nature Communications(2021)10.1038/s41467-021-22139-7

N/A

0.773DataRank · unranked

172 citations

David Y. Takeda, Ji-Heui Seo, Justin H. Hwang, Sheng-Yu Ku, Rand Arafeh +36 more

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma

Nature Communications(2021)10.1038/s41467-021-21068-9

N/A

0.770DataRank · unranked

169 citations

David A. Braun, Sachet A. Shukla, Wenting Pan, Xīn Gào, Yue Hou +48 more

MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets

Nature Communications(2022)10.1038/s41467-022-30257-z

N/A

0.762DataRank · unranked

160 citations

Nadia Boufaied, Tarek Hallal, Avery Feit, Anna de Polo, Adrienne Luoma +30 more

Liquid biopsy epigenomic profiling for cancer subtyping

Nature Medicine(2023)10.1038/s41591-023-02605-z

N/A

0.722DataRank · unranked

122 citations

Ji-Heui Seo, Matthew P. Davidsohn, Brad Fortunato, Karl Semaan, Shahabbedin Sotudian +38 more

Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome

JCI Insight(2022)10.1172/jci.insight.157164

N/A

0.686DataRank · unranked

19 citations

Lisha G. Brown, Jennifer L. Conner, Holly M. Nguyen, Nadia Boufaied, Sarah Abou Alaiwi +15 more

Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors

Cancer Immunology Research(2020)10.1158/2326-6066.cir-19-0866

N/A

0.657DataRank · unranked

79 citations

Amin H. Nassar, Wanling Xie, Ziad Bakouny, Jacob E. Berchuck, David A. Braun +27 more

Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

Cancer Discovery(2022)10.1158/2159-8290.cd-22-0692

N/A

0.641DataRank · unranked

71 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer

Nature Communications(2020)10.1038/s41467-020-17325-y

N/A

0.568DataRank · unranked

43 citations

Bharath Saravanan, Anurag Kumar Singh, Ranveer Singh Jayani, Ashwin Nair, Umer Farooq +9 more

Patterns of structural variation define prostate cancer across disease states

JCI Insight(2022)10.1172/jci.insight.161370

N/A

0.505DataRank · unranked

28 citations

Minjeong Ko, Anna C. H. Hoge, Kelsey Luu, Yuzhen Liu, Magdalena L Russell +13 more

Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer

Cell Reports(2024)10.1016/j.celrep.2024.115089

N/A

0.455DataRank · unranked

12 citations

Mannan Nouri, Jiaqian Liang, Shaoyong Chen, Andreas Varkaris, Betul Ersoy-Fazlioglu +15 more

A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus

Nature Communications(2023)10.1038/s41467-023-40616-z

N/A

0.396DataRank · unranked

13 citations

Viktória Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Bálint Pataki, Dezső Ribli +20 more

Nucleosome patterns in circulating tumor DNA reveal transcriptional regulation of advanced prostate cancer phenotypes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.21.496879

N/A

0.393DataRank · unranked

8 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Adam J. Kreitzman, Jay F. Sarthy +28 more

Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma

Journal of Clinical Investigation(2026)10.1172/jci195725

N/A

0.241DataRank · unranked

4 citations

Karl Semaan, Jiao Li, Ze Zhang, Prathyusha Konda, Ananthan Sadagopan +27 more

Patterns of Structural Variation Define Prostate Cancer Across Disease States

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.09.475586

N/A

0.241DataRank · unranked

4 citations

Minjeong Ko, Anna C. H. Hoge, Kelsey Luu, Yuzhen Liu, Magdalena L Russell +13 more

Integrative Molecular Characterization of Sarcomatoid and Rhabdoid Renal Cell Carcinoma Reveals Determinants of Poor Prognosis and Response to Immune Checkpoint Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.121806

N/A

0.208DataRank · unranked

3 citations

David A. Braun, Sachet A. Shukla, Wenting Pan, Xīn Gào, Yue Hou +47 more

Risk Alleles Identified in Genome-Wide Association Studies Are Associated with Expression Quantitative Trait Loci in Chronic Lymphocytic Leukemia.

Blood(2012)10.1182/blood.v120.21.2875.2875

N/A

0.104DataRank · unranked

1 citations

Lillian Werner, Megan Hanna, Ma. Reina Improgo, Nathalie Pochet, Stacey M. Fernandes +8 more

A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer

Cell Reports(2022)10.1016/j.celrep.2022.110417

N/A

0.104DataRank · unranked

1 citations

Nebiyou Y. Metaferia, Marina F. Nogueira, Sarah Abou Alaiwi, Ji-Heui Seo, Justin H. Hwang +13 more

Plasma Kidney Injury Molecule-1 for Preoperative Prediction of Renal Cell Carcinoma Versus Benign Renal Masses, and Association With Clinical Outcomes

Journal of Clinical Oncology(2024)10.1200/jco.23.00699

N/A

0DataRank · unranked

25 citations

Valérie Gaborieau, Samuel M. Niman, Anush Mukeria, Xiaowen Liu, Krishna P. Maremanda +14 more

Increased chromatin accessibility mediated by nuclear factor I drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.10.575110

N/A

0DataRank · unranked

1 citations

Mannan Nouri, Jiaqian Liang, Andreas Varkaris, Betul Ersoy-Fazlioglu, Olga Voznesensky +14 more

Plasma epigenomic profiling reveals treatment-emergent squamous transformation in prostate cancer

npj Precision Oncology(2025)10.1038/s41698-025-01031-3

N/A

0DataRank · unranked

7 citations

Rashad Nawfal, John Canniff, Hunter Savignano, Ji-Heui Seo, Stephanie Siegmund +17 more

Targeting AXL can effectively overcome c-Met-induced therapeutic resistance in renal cancer and promote tumor cell death through increased oxidative stress

Cancer Letters(2025)10.1016/j.canlet.2025.217984

N/A

0DataRank · unranked

3 citations

Marc Machaalani, Laxminarayan Rawat, Johannes Wedel, Saba Tabasum, Yuzuru Sasamoto +14 more

Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.31.673338

N/A

0DataRank · unranked

1 citations

Karl Semaan, Jiao Li, Ananthan Sadagopan, John Canniff, Noa Phillips +27 more

Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma

Cell Reports(2024)10.1016/j.celrep.2024.114350

N/A

0DataRank · unranked

29 citations

Karl Semaan, Marc Eid, Ji-Heui Seo, Simon Garinet, Matthew P. Davidsohn +34 more

Allele-Specific QTL Fine Mapping with PLASMA

The American Journal of Human Genetics(2020)10.1016/j.ajhg.2019.12.011

N/A

0DataRank · unranked

18 citations

Anamay Shetty, Edward O’Connor, Connor Bell, Mark M. Pomerantz, Matthew L. Freedman +2 more

Ovarian Cancer Risk Variants Are Enriched in Histotype-Specific Enhancers and Disrupt Transcription Factor Binding Sites

The American Journal of Human Genetics(2020)10.1016/j.ajhg.2020.08.021

N/A

0DataRank · unranked

27 citations

Pei-Chen Peng, Simon G. Coetzee, Jonathan P. Tyrer, Alberto Luiz P. Reyes, Rosario I. Corona +14 more

Subtype Heterogeneity and Epigenetic Convergence in Neuroendocrine Prostate Cancer

(2020)10.1101/2020.09.13.291328

N/A

0DataRank · unranked

21 citations

Yingtian Xie, Alba Font‐Tello, Klothilda Lim, Sudeepa Syamala, Xintao Qiu +30 more

EZH2 inhibition activates a dsRNA–STING–interferon stress axis that potentiates response to PD-1 checkpoint blockade in prostate cancer

Nature Cancer(2021)10.1038/s43018-021-00185-w

N/A

0DataRank · unranked

241 citations

Anjali V. Sheahan, Deborah L. Burkhart, Sylvan C. Baca, Nadia Boufaied, Yin Liu +32 more

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer

Nature Communications(2021)10.1038/s41467-021-27077-y

N/A

0DataRank · unranked

80 citations

Yiming Wu, Mannan Nouri, Sándor Spisák, Joshua W. Russo, Adam G. Sowalsky +11 more

H3K27ac HiChIP in prostate cell lines identifies risk genes for prostate cancer susceptibility

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.11.007

N/A

0DataRank · unranked

51 citations

Ji-Heui Seo, Tommer Schwarz, Malika Freund, Ruth Johnson, Sándor Spisák +6 more

Allele-specific epigenetic activity in prostate cancer and normal prostate tissue implicates prostate cancer risk mechanisms

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.09.008

N/A

0DataRank · unranked

11 citations

Ji-Heui Seo, Connor Bell, Edward O’Connor, Mark M. Pomerantz, Matthew L. Freedman +2 more

Exonic variants undergoing allele-specific selection in cancers

BMC Medical Genomics(2021)10.1186/s12920-021-00984-1

N/A

0DataRank · unranked

1 citations

Yuanyuan Zeng, Janet Wang, Hongkun Fang, Jintao Guo, Liying Yu +5 more

A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

medRxiv(2021)10.1101/2021.06.28.21259290

N/A

0DataRank · unranked

8 citations

Rosario I. Corona, Pik Fang Kho, Paul D.P. Pharoah, Ji-Heui Seo, Matthew L. Freedman +12 more

Allele-specific epigenetic activity in prostate cancer and normal prostate tissue implicates prostate cancer risk mechanisms

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.02.446619

N/A

0DataRank · unranked

2 citations

Ji-Heui Seo, Connor Bell, Edward O’Connor, Mark M. Pomerantz, Matthew L. Freedman +2 more

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.04.463081

N/A

0DataRank · unranked

2 citations

Ka-wing Fong, Fang Wang, Galina Gritsina, Sylvan C. Baca, Jacob E. Berchuck +9 more

A multi-level investigation of the genetic relationship between endometriosis and ovarian cancer histotypes

Cell Reports Medicine(2022)10.1016/j.xcrm.2022.100542

N/A

0DataRank · unranked

60 citations

Rosario I. Corona, Pik Fang Kho, Paul D.P. Pharoah, Ji-Heui Seo, Matthew L. Freedman +12 more

The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response

Cancer Research(2022)10.1158/0008-5472.can-21-3552

N/A

0DataRank · unranked

40 citations

Elio Adib, Sarah Abou Alaiwi, Amit K. Dash, Jin Na Shin, Dallin Lowder +27 more

Distal gene regulation mediated by non-coding RNAs contributes to germline risk for breast and prostate cancer

medRxiv(2022)10.1101/2022.02.08.22270601

N/A

0DataRank · unranked

1 citations

Paige Lee, Tommer Schwarz, Pan Zhang, Matthew L. Freedman, Alexander Gusev +5 more

A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.29.486217

N/A

0DataRank · unranked

1 citations

Xintao Qiu, Ariel Feiglin, Xiaoyong Fu, Sándor Spisák, Avery Feit +20 more

Germline variants associated with immunotherapy-related adverse events

medRxiv(2022)10.1101/2022.04.10.22273627

N/A

0DataRank · unranked

0 citations

Sarah Abou Alaiwi, Wenxin Xu, Vivek Naranbhai, Amin H. Nassar, Ziad Bakouny +26 more

Germline determinants of the prostate tumor genome

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.16.516773

N/A

0DataRank · unranked

0 citations

Jiapei Yuan, Tommer Schwarz, Julie Livingstone, Natalie S. Fox, Weerachai Jaratlerdsiri +36 more

Epigenomic charting and functional annotation of risk loci in renal cell carcinoma

Nature Communications(2023)10.1038/s41467-023-35833-5

N/A

0DataRank · unranked

34 citations

Sarah Abou Alaiwi, Sylvan C. Baca, Elio Adib, Rosario I. Corona, Ji-Heui Seo +31 more

Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.11.536378

N/A

0DataRank · unranked

6 citations

Heidi Chang, Pak Yu, Forough Abbasi, Xianzhi Lin, Jessica Reddy +7 more

Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

eLife(2023)10.7554/elife.86360.1

N/A

0DataRank · unranked

1 citations

Heidi Chang, Pak Yu, Forough Abbasi, Xianzhi Lin, Jessica Reddy +7 more

Data from Haplotype Analysis of the HSD17B1 Gene and Risk of Breast Cancer: A Comprehensive Approach to Multicenter Analyses of Prospective Cohort Studies

(2023)10.1158/0008-5472.c.6495299.v1

N/A

0DataRank · unranked

0 citations

David G. Cox, Howard M. Cann, Sholom Wacholder, Rudolf Kaaks, Brian E. Henderson +34 more

Data from Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

(2023)10.1158/2159-8290.c.6549837.v1

N/A

0DataRank · unranked

0 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

Data from Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes

(2023)10.1158/2159-8290.c.6549837.v2

N/A

0DataRank · unranked

0 citations

Robert D. Patton, Anna-Lisa Doebley, Brian Hanratty, Mohamed Adil, Adam J. Kreitzman +28 more

Rewiring of master transcription factor cistromes during high-grade serous ovarian cancer development

eLife(2023)10.7554/elife.86360

N/A

0DataRank · unranked

0 citations

Heidi Chang, Pak Yu, Forough Abbasi, Xianzhi Lin, Jessica Reddy +7 more

Detecting Small Cell Transformation in Patients with Advanced EGFR Mutant Lung Adenocarcinoma through Epigenomic cfDNA Profiling

Clinical Cancer Research(2024)10.1158/1078-0432.ccr-24-0466

N/A

0DataRank · unranked

32 citations

Catherine B. Meador, Xintao Qiu, Ji-Heui Seo, Matthew P. Davidsohn, Hunter Savignano +20 more