Dennis E. Kyle

MedicineComputer SciencePharmacology, Toxicology and Pharmaceutics

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

1.9Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples

Wellcome Open Research(2023)10.12688/wellcomeopenres.18681.1

Top 11%

1.9DataRank

Top 11%154 citations

Muzamil Mahdi Abdel Hamid, Mohamed Hassan Abdelraheem, Desmond Omane Acheampong, Ambroise D. Ahouidi, Mozam Ali +95 more

Papers

Driven by 37 papers — median percentile 89. Top paper: “Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples”.

Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples

Wellcome Open Research(2023)10.12688/wellcomeopenres.18681.1

Top 11%

1.9DataRank

Top 11%154 citations

Muzamil Mahdi Abdel Hamid, Mohamed Hassan Abdelraheem, Desmond Omane Acheampong, Ambroise D. Ahouidi, Mozam Ali +95 more

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies–Activities Against Blood Stage P. falciparum Including PfKI3 C580Y Mutants and Liver Stage P. berghei Parasites

Frontiers in Chemistry(2020)10.3389/fchem.2019.00901

N/A

0DataRank · unranked

22 citations

Vivian Padín-Irizarry, Mariëtte van der Watt, Janette Reader, Wilna Liebenberg, Lubbe Wiesner +8 more

Bioactivity of Spongian Diterpenoid Scaffolds from the Antarctic Sponge Dendrilla antarctica

Marine Drugs(2020)10.3390/md18060327

N/A

0DataRank · unranked

21 citations

Andrew J. Shilling, Jessie L. Allen, Ala Azhari, Alison Roth, Lindsey N. Shaw +6 more

Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis.

UNC Libraries(2020)10.17615/kdfe-fh36

N/A

0DataRank · unranked

3 citations

R R Tidwell, Dennis E. Kyle, M A Allen, M Grogl, J E Hall +2 more

The transcriptome of Balamuthia mandrillaris trophozoites for structure-based drug design

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.29.178905

N/A

0DataRank · unranked

2 citations

Christopher A. Rice, Justin K. Craig, Rooksana E. Noorai, Jacquelyn McDonald, Sandhya Subramanian +8 more

Characterization of the Tubovesicular Network in Plasmodium vivax Liver Stage Hypnozoites and Schizonts

Frontiers in Cellular and Infection Microbiology(2021)10.3389/fcimb.2021.687019

N/A

0DataRank · unranked

24 citations

Steven P. Maher, Dora Posfai, Michaël Tran, McKenna C. Crawford, Amélie Vantaux +4 more

The transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design

Scientific Reports(2021)10.1038/s41598-021-99903-8

N/A

0DataRank · unranked

22 citations

Christopher A. Rice, Justin K. Craig, Rooksana E. Noorai, Jacquelyn McDonald, Sandhya Subramanian +8 more

EdU Incorporation To Assess Cell Proliferation and Drug Susceptibility in Naegleria fowleri

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.00017-21

N/A

0DataRank · unranked

17 citations

Dennis E. Kyle, Emma V. Troth

Altered cleavage of Caspase-1 in hepatocytes limits control of malaria in the liver

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.28.427517

N/A

0DataRank · unranked

4 citations

Barun Poudel, Rodrigo P. Baptista, Kristen Peissig, Lisa S. Hancox, Justine C. Shiau +9 more

Alkyne modified purines for assessing activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.12.464062

N/A

0DataRank · unranked

0 citations

Grant Lawrence, Steven P. Maher, Amélie Vantaux, Benoît Witkowski, Justine C. Shiau +8 more

Direct type I interferon signaling in hepatocytes controls malaria

Cell Reports(2022)10.1016/j.celrep.2022.111098

N/A

0DataRank · unranked

30 citations

Kristen Peissig, Michael P. Walker, Justine C. Shiau, Carson Bowers, Dennis E. Kyle +4 more

Streamlining sporozoite isolation from mosquitoes by leveraging the dynamics of migration to the salivary glands

Malaria Journal(2022)10.1186/s12936-022-04270-y

N/A

0DataRank · unranked

30 citations

Justine C. Shiau, Blandine Franke‐Fayard, Lisa M. Shollenberger, Donald A. Harn, Dennis E. Kyle +2 more

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine

The Journal of Infectious Diseases(2022)10.1093/infdis/jiac469

N/A

0DataRank · unranked

26 citations

Peter Christensen, Annie Racklyeft, Satish K. Dhingra, Adeline C. Y. Chua, Caroline Remmert +13 more

Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp.

International Journal for Parasitology(2022)10.1016/j.ijpara.2022.03.003

N/A

0DataRank · unranked

10 citations

Grant Lawrence, Steven P. Maher, Amélie Vantaux, Benoît Witkowski, Justine C. Shiau +8 more

Chemistry and Bioactivity of the Deep-Water Antarctic Octocoral Alcyonium sp.

Marine Drugs(2022)10.3390/md20090576

N/A

0DataRank · unranked

7 citations

Hiran Malinda Lamabadu Warnakulasur Patabendige, Ala Azhari, Xingmin Sun, Dennis E. Kyle, Nerida G. Wilson +2 more

Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)

ACS Omega(2022)10.1021/acsomega.2c01099

N/A

0DataRank · unranked

4 citations

Yogesh A. Sonawane, Steven P. Maher, Anne‐Marie Zeeman, Victor Chaumeau, Amélie Vantaux +14 more

Polychlorinated cyclopentenes from a marine derived Periconia sp. (strain G1144)

Phytochemistry(2022)10.1016/j.phytochem.2022.113200

N/A

0DataRank · unranked

4 citations

Robert A. Shepherd, Sonja L. Knowles, Manuel Rangel‐Grimaldo, Huzefa A. Raja, Zoie L. Bunch +7 more

Blood meals from ‘dead-end’ vertebrate hosts enhance transmission potential of malaria-infected mosquitoes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.24.521872

N/A

0DataRank · unranked

4 citations

Justine C. Shiau, Cury Rafael Sadock de Freitas, Dennis E. Kyle, Ashutosh K. Pathak

Streamlining sporozoite isolation from mosquitoes by leveraging the dynamics of migration to the salivary glands

Research Square(2022)10.21203/rs.3.rs-1514945/v1

N/A

0DataRank · unranked

0 citations

Justine C. Shiau, Blandine Franke‐Fayard, Lisa M. Shollenberger, Donald A. Harn, Dennis E. Kyle +2 more

Blood meals from ‘dead-end’ vertebrate hosts enhance transmission potential of malaria-infected mosquitoes

One Health(2023)10.1016/j.onehlt.2023.100582

N/A

0DataRank · unranked

18 citations

Justine C. Shiau, Rafael C.S. Freitas, Dennis E. Kyle, Ashutosh K. Pathak

AIM2 sensors mediate immunity to Plasmodium infection in hepatocytes

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2210181120

N/A

0DataRank · unranked

16 citations

Barun Poudel, Rodrigo P. Baptista, Kristen Peissig, Lisa S. Hancox, Justine C. Shiau +9 more

Characterization of the extracellular vesicles, ultrastructural morphology, and intercellular interactions of multiple clinical isolates of the brain-eating amoeba, Naegleria fowleri

Frontiers in Microbiology(2023)10.3389/fmicb.2023.1264348

N/A

0DataRank · unranked

16 citations

Peter J. Bush, Gabriela Grigorean, Dennis E. Kyle, A. Cassiopeia Russell

Sheptide A: an antimalarial cyclic pentapeptide from a fungal strain in the Herpotrichiellaceae

The Journal of Antibiotics(2023)10.1038/s41429-023-00655-6

N/A

0DataRank · unranked

3 citations

Cody E. Earp, Kristóf B. Cank, Huzefa A. Raja, Joanna E. Burdette, Steven P. Maher +8 more

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.526483

N/A

0DataRank · unranked

23 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Manoj Kumar Gupta +43 more

In Vitro Antimalarial Activity of Trichothecenes against Liver and Blood Stages of Plasmodium Species

Journal of Natural Products(2024)10.1021/acs.jnatprod.3c01019

N/A

0DataRank · unranked

5 citations

Steven P. Maher, Yingzhao Zhao, Caitlin Cooper, Sagan T. de Castro, Julie Péneau +5 more

The influence of oviposition status on measures of transmission potential in malaria-infected mosquitoes depends on sugar availability

Parasites & Vectors(2024)10.1186/s13071-024-06317-2

N/A

0DataRank · unranked

3 citations

Nathan Garcia-Diaz, Dennis E. Kyle, Ashutosh K. Pathak, Justine C. Shiau

Optimization of diastereomeric dihydropyridines as antimalarials

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116599

N/A

0DataRank · unranked

2 citations

Yingzhao Zhao, Prakash T. Parvatkar, Julie Maier, Tina Mutka, Alexis N. LaCrue +17 more

Screening the Global Health Priority Box against Plasmodium berghei liver stage parasites using an inexpensive luciferase detection protocol

Malaria Journal(2024)10.1186/s12936-024-05155-y

N/A

0DataRank · unranked

3 citations

Caitlin Cooper, Olivia McWhorter, Ritu Sharma, Anne Elliot, Anthony A. Ruberto +5 more

A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites

eLife(2024)10.7554/elife.98221

N/A

0DataRank · unranked

3 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Mohit Gupta +43 more

Oviposition status and sugar availability influence measures of transmission potential in malaria-infected mosquitoes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.25.577126

N/A

0DataRank · unranked

0 citations

Nathan Garcia-Diaz, Dennis E. Kyle, Ashutosh K. Pathak, Justine C. Shiau

Discovery and Optimization of a Novel Carboxamide Scaffold with Selective Antimalarial Activity

ChemRxiv(2024)10.26434/chemrxiv-2024-h5zgs

N/A

0DataRank · unranked

0 citations

Roger Trombley, Maris Podgurski, Anthony A. Ruberto, Meng Cui, Caitlin Cooper +9 more

Author response: A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

(2024)10.7554/elife.98221.1.sa4

N/A

0DataRank · unranked

0 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Manoj Kumar Gupta +43 more

Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

Cell Host & Microbe(2025)10.1016/j.chom.2025.03.008

N/A

0DataRank · unranked

9 citations

Clyde Schmidt-Silva, Carson Bowers, Nana Appiah Essel Charles-Chess, Cristina Samuel, Justine C. Shiau +8 more

Discovery and optimization of a novel carboxamide scaffold with selective antimalarial activity

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117572

N/A

0DataRank · unranked

5 citations

Roger Trombley, Maris Podgurski, Anthony A. Ruberto, Meng Cui, Caitlin Cooper +9 more

Characterization of β-Carboline Derivatives Reveals a High Barrier to Resistance and Potent Activity against Ring-Stage and DHA-Induced Dormant Plasmodium falciparum

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00714

N/A

0DataRank · unranked

2 citations

Joshua H. Butler, Lyric A. Wardlaw, Emilio F. Merino, Victoria Mendiola, Caitlin Cooper +12 more

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

Cell chemical biology(2020)10.1016/j.chembiol.2020.03.009

N/A

0DataRank · unranked

48 citations

Steven P. Maher, Camille Roesch, Amélie Vantaux, Kayla Sylvester, Julie Péneau +5 more

A drug repurposing approach reveals targetable epigenetic pathways in Plasmodium vivax hypnozoites

eLife(2025)10.7554/elife.98221.2

N/A

0DataRank · unranked

1 citations

Malina A. Bakowski, Amélie Vantaux, Erika L. Flannery, Chiara Andolina, Mohit Gupta +43 more

Dennis E. Kyle

Indexed papers

Top data-sharing exemplar

Papers