🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

José Soto

Broad Institute

ORCID: 0000-0002-0317-6664

Also affiliated with James S. McDonnell Foundation, Washington University in St. Louis, Universidad del Valle

Biochemistry, Genetics and Molecular BiologyMedicineAgricultural and Biological Sciences

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
11.0Author DataRank

Indexed papers

3in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8
Top 3%
6.7DataRank
Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Papers

Driven by 10 papers — median percentile 94. Top paper: “A structural variation reference for medical and population genetics”.

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8
Top 3%
6.7DataRank
Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Nature Communications(2020)10.1038/s41467-019-12438-5
N/A
5.6DataRank · unranked
143 citations

James Zou, Beryl B. Cummings, Jessica Alföldi, Laurent C. Francioli, Laura D. Gauthier +174 more

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nature Communications(2020)10.1038/s41467-019-10717-9
N/A
5.2DataRank · unranked
191 citations

Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans +181 more

The effect of LRRK2 loss-of-function variants in humans

Nature Medicine(2020)10.1038/s41591-020-0893-5
N/A
4.9DataRank · unranked
114 citations

Irina M. Armean, Aaron Kleinman, Jamie L. Marshall, Eric V. Minikel, Julia K. Goodrich +214 more

Mitochondrial DNA variation across 56,434 individuals in gnomAD

Genome Research(2022)10.1101/gr.276013.121
Top 6%
3.6DataRank
Top 6%156 citations

Nicole J. Lake, Nicholas A. Watts, Megan Shand, Andrea Haessly, Laura D. Gauthier +12 more

The mutational constraint spectrum quantified from variation in 141,456 humans

Nature(2020)10.1038/s41586-020-2308-7
N/A
1.4DataRank · unranked
9958 citations

Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo S. Wang +187 more

Transcript expression-aware annotation improves rare variant interpretation

Nature(2020)10.1038/s41586-020-2329-2
N/A
0.796DataRank · unranked
201 citations

Konrad J. Karczewski, Ditte Demontis, Eleanor G. Seaby, Nicholas A. Watts, Moriel Singer-Berk +177 more

Mitochondrial DNA variation across 56,434 individuals in gnomAD

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.23.453510
Top 27%
0.757DataRank
Top 27%20 citations

Nicole J. Lake, Nicholas A. Watts, Megan Shand, Andrea Haessly, Laura D. Gauthier +12 more

Unveiling ancestral threads: Exploring CCR5 ∆32 mutation frequencies in Colombian populations for HIV/AIDS therapeutics

Infection Genetics and Evolution(2024)10.1016/j.meegid.2024.105680
N/A
0DataRank · unranked
4 citations

Thanh Long Nguyen, Juan Esteban Gallo, Leonardo Mariño‐Ramírez, José Soto, Adalberto Sánchez +3 more

Metabolomic profile associated with preeclampsia and its severity: a case-control study in Colombian pregnant women

Scientific Reports(2025)10.1038/s41598-025-00154-8
N/A
0DataRank · unranked
0 citations

Paula K. Bautista‐Niño, Doris Cristina Quintero-Lesmes, Carlos Riaño, José Soto, Jie Hu +3 more