David J. Orlicky

University of Colorado Anschutz Medical Campus

Also affiliated with University of Colorado Denver

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 62 papers. Top paper: “Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model”.

Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model

Nature Genetics(2023)10.1038/s41588-023-01399-7

N/A

1.4DataRank · unranked

115 citations

Ross Minter, Jessica Baxter, Congwu Chi, Matthew D. Galbraith, Kathryn D. Tuttle +27 more

Inhaled silica nanoparticles cause chronic kidney disease in rats

American Journal of Physiology-Renal Physiology(2022)10.1152/ajprenal.00021.2022

N/A

1.3DataRank · unranked

46 citations

Keegan L. Rogers, David J. Orlicky, Arthur Stem, Joshua W. Schaeffer, Gabriela García +16 more

Lipidomics and Redox Lipidomics Indicate Early Stage Alcohol‐Induced Liver Damage

Hepatology Communications(2021)10.1002/hep4.1825

N/A

0.791DataRank · unranked

20 citations

Wan Ying Tan, Yang Li, John A. Bowden, Atiye Ahmadireskety, Andrew Patt +20 more

Vasopressin mediates fructose-induced metabolic syndrome by activating the V1b receptor

JCI Insight(2020)10.1172/jci.insight.140848

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0.604DataRank · unranked

55 citations

Thomas Jensen, Masanari Kuwabara, David J. Orlicky, Christina Cicerchi, Nanxing Li +11 more

Identification of Dose-Dependent DNA Damage and Repair Responses From Subchronic Exposure to 1,4-Dioxane in Mice Using a Systems Analysis Approach

Toxicological Sciences(2021)10.1093/toxsci/kfab030

N/A

0.550DataRank · unranked

15 citations

Jaya Prakash Golla, Álvaro J. Santos‐Neto, David J. Orlicky, Rolando García-Milian, Ying Chen +10 more

Oxidative stress and genotoxicity in 1,4-dioxane liver toxicity as evidenced in a mouse model of glutathione deficiency

The Science of The Total Environment(2021)10.1016/j.scitotenv.2021.150703

N/A

0.515DataRank · unranked

30 citations

Yewei Wang, Georgia Charkoftaki, David J. Orlicky, Emily A. Davidson, Fengjie Wan +4 more

Prophage terminase with tRNase activity sensitizes Salmonella enterica to oxidative stress

Science(2024)10.1126/science.adl3222

N/A

0.470DataRank · unranked

22 citations

Sashi Kant, Lin Liu, Ju-Sim Kim, David J. Orlicky, Michael McClelland +2 more

Anaerobic respiration of host-derived methionine sulfoxide protects intracellular Salmonella from the phagocyte NADPH oxidase

Cell Host & Microbe(2024)10.1016/j.chom.2024.01.004

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0.434DataRank · unranked

17 citations

Lin Liu, Sashi Kant, David J. Orlicky, Siva R. Uppalapati, Alyssa Margolis +7 more

Age-Related Intestinal Dysbiosis and Enrichment of Gut-specific Bacteria in the Lung Are Associated With Increased Susceptibility to Streptococcus pneumoniae Infection in Mice

Frontiers in Aging(2022)10.3389/fragi.2022.859991

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0.396DataRank · unranked

13 citations

Holly J. Hulsebus, Kevin M. Najarro, Lauren E. Giesy, Daniel N. Frank, David J. Orlicky +2 more

Liver sinusoidal endothelial cells regulate the balance between hepatic immunosuppression and immunosurveillance

Frontiers in Immunology(2025)10.3389/fimmu.2024.1497788

N/A

0.396DataRank · unranked

13 citations

Hadeel A. Khammash, Anjelica M. Miranda, Lauren N. Rutt, Shannon M. Twardy, Paige Anton +7 more

Chemopreventive efficacy of silibinin against basal cell carcinoma growth and progression in UVB-irradiated Ptch+/– mice

Carcinogenesis(2022)10.1093/carcin/bgac023

N/A

0.292DataRank · unranked

6 citations

Komal Raina, Vasundhara R Tiku, Akhilendra Kumar Maurya, David J. Orlicky, Zhiying You +7 more

Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption

Antioxidants(2021)10.3390/antiox10030359

N/A

0.292DataRank · unranked

6 citations

Jean A. Kundert, Justin R. Prigge, Julie Amato, Allison Perez, Lucia Coppo +6 more

CYP2E1 in 1,4-dioxane metabolism and liver toxicity: insights from CYP2E1 knockout mice study

Archives of Toxicology(2024)10.1007/s00204-024-03811-5

N/A

0.289DataRank · unranked

4 citations

Georgia Charkoftaki, David J. Orlicky, Emily A. Davidson, Reza Aalizadeh, Ning Sun +5 more

Quantifying Protein Acetylation in Diabetic Nephropathy from Formalin‐Fixed Paraffin‐Embedded Tissue

PROTEOMICS - CLINICAL APPLICATIONS(2024)10.1002/prca.202400018

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0.241DataRank · unranked

4 citations

Peter Harris, Cole R. Michel, Courtney McGinnis, Rooban B. Nahomi, Mohammed A. Assiri +8 more

Absence of IκBβ/NFκB signaling does not attenuate acetaminophen‐induced hepatic injury

The Anatomical Record(2022)10.1002/ar.25126

N/A

0.165DataRank · unranked

2 citations

Maya R. Grayck, William C. McCarthy, Lijun Zheng, Oscar A. Lacayo, Laura G. Sherlock +4 more

Dietary fat promotes antibiotic-induced Clostridioides difficile mortality in mice

npj Biofilms and Microbiomes(2022)10.1038/s41522-022-00276-1

N/A

0.165DataRank · unranked

2 citations

Casey Martin, David J. Orlicky, Kathleen L. Arnolds, Nichole Nusbacher, Nancy Moreno-Huizar +4 more

Liver metabolomics identifies bile acid profile changes at early stages of alcoholic liver disease in mice

Chemico-Biological Interactions(2022)10.1016/j.cbi.2022.109931

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0DataRank · unranked

23 citations

Wan Ying Tan, Pablo Berríos‐Cárcamo, David J. Orlicky, Jaya Prakash Golla, Rolando García-Milian +5 more

Ethanol Intoxication Impairs Respiratory Function and Bacterial Clearance and Is Associated With Neutrophil Accumulation in the Lung After Streptococcus pneumoniae Infection

Frontiers in Immunology(2022)10.3389/fimmu.2022.884719

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0DataRank · unranked

19 citations

Kevin M. Najarro, Rachel H. McMahan, Devin M. Boe, David J. Orlicky, Elizabeth J. Kovacs +1 more

Perilipin-2 promotes lipid droplet-plasma membrane interactions that facilitate apocrine lipid secretion in secretory epithelial cells of the mouse mammary gland

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.958566

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0DataRank · unranked

15 citations

David J. Orlicky, Andrew E. Libby, Monica Dzieciatkowska, Mark S. Ladinsky, James L. McManaman +1 more

The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease

PLoS ONE(2022)10.1371/journal.pone.0276879

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0DataRank · unranked

9 citations

Aimee L. Anderson, Michael W. Devereux, David J. Orlicky, Cole R. Michel, Dennis R. Petersen +5 more

Oxidative stress, glutathione, and CYP2E1 in 1,4-dioxane liver cytotoxicity and genotoxicity: insights from animal models

Current Opinion in Environmental Science & Health(2022)10.1016/j.coesh.2022.100389

N/A

0DataRank · unranked

6 citations

Georgia Charkoftaki, Emily A. Davidson, David J. Orlicky, Robyn L. Tanguay, David C. Thompson +3 more

Interferon receptor gene dosage determines diverse hallmarks of Down syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.03.478982

N/A

0DataRank · unranked

14 citations

Ross Minter, Jessica Baxter, Congwu Chi, Kathryn D. Tuttle, Neetha Paul Eduthan +26 more

Phosphate depletion in insulin-insensitive skeletal muscle drives AMPD activation and sarcopenia in chronic kidney disease

iScience(2023)10.1016/j.isci.2023.106355

N/A

0DataRank · unranked

18 citations

Christina Cicerchi, Gabriela García, David J. Orlicky, Peter Stenvinkel, Richard J. Johnson +2 more

Thioredoxin reductase 1 regulates hepatic inflammation and macrophage activation during acute cholestatic liver injury

Hepatology Communications(2023)10.1097/hc9.0000000000000020

N/A

0DataRank · unranked

18 citations

Aimee L. Anderson, Colin G. Miller, Reed C. Noyd, Michael W. Devereaux, Nata Balasubramaniyan +4 more

Endogenous Fructose Production and Metabolism Drive Metabolic Dysregulation and Liver Disease in Mice with Hereditary Fructose Intolerance

Nutrients(2023)10.3390/nu15204376

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0DataRank · unranked

13 citations

David J. Orlicky, Masanari Kuwabara, Christina Cicerchi, Michelle G. Pedler, Mark Petrash +4 more

Estrogen and Androgen Receptor Status in Uterosacral Ligaments of Women with Pelvic Organ Prolapse Stratified by the Pelvic Organ Prolapse Histology Quantification System

Reproductive Sciences(2023)10.1007/s43032-023-01283-z

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0DataRank · unranked

8 citations

Elizabeth E. Smith, Rachel Bok, Marsha K. Guess, Lauren G. Rascoff, Jaime Arruda +4 more

Pharmacologic inhibition of HNF4α prevents parenteral nutrition associated cholestasis in mice

Scientific Reports(2023)10.1038/s41598-023-33994-3

N/A

0DataRank · unranked

3 citations

Michael W. Devereaux, David J. Orlicky, Ronald J. Sokol, Swati Ghosh

Ethanol exacerbates pulmonary complications after burn injury in mice, regardless of frequency of ethanol exposures

Burns(2023)10.1016/j.burns.2023.07.008

N/A

0DataRank · unranked

3 citations

Travis Walrath, Brenda J. Curtis, David J. Orlicky, Rachel H. McMahan, Elizabeth J. Kovacs +1 more

Endocrine pancreas-specific Gclc gene deletion causes a severe diabetes phenotype

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.13.544855

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0DataRank · unranked

4 citations

Ying Chen, Surendra Singh, David J. Orlicky, Brian Thompson, Yewei Wang +9 more

Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice

Scientific Reports(2024)10.1038/s41598-024-64586-4

N/A

0DataRank · unranked

10 citations

Amy S. Li, Benjamin R. Griffin, Hyo‐Wook Gil, David J. Orlicky, Benjamin Fox +14 more

Investigating the role of Wnt3a and Wnt5a as critical factors of hepatic stellate cell activation in acute toxicant-induced liver injury

Cell Biology and Toxicology(2024)10.1007/s10565-024-09956-4

N/A

0DataRank · unranked

11 citations

David J. Orlicky, Rebecca L. McCullough, Lauren N. Rutt

Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance

Communications Biology(2024)10.1038/s42003-024-06539-1

N/A

0DataRank · unranked

3 citations

David J. Orlicky, Masanari Kuwabara, Mehdi A. Fini, Dean R. Tolan, Richard J. Johnson +2 more

Reducing the excessive inflammation after burn injury in aged mice by maintaining a healthier intestinal microbiome

The FASEB Journal(2024)10.1096/fj.202401020r

N/A

0DataRank · unranked

6 citations

Kevin M. Najarro, Lauren E. Giesy, Shanawaj Khair, David J. Orlicky, Rachel H. McMahan +2 more

Implications of neonatal absence of innate immune mediated NFκB/AP1 signaling in the murine liver

Pediatric Research(2024)10.1038/s41390-024-03071-0

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0DataRank · unranked

2 citations

William C. McCarthy, Mack Solar, Natarajan Balasubramaniyan, Lijun Zheng, David J. Orlicky +2 more

Antigen-driven CD8 + T cell clonal expansion is a prominent feature of MASH in humans and mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.20.583964

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0DataRank · unranked

1 citations

Destiny DeNicola, Megan E. Ferguson, Radleigh G. Santos, Clemencia Pinilla, Michael Kriss +5 more

Myeloid Cells and Sphingosine-1-Phosphate Are Required for TCRαβ Intraepithelial Lymphocyte Recruitment to the Colon Epithelium

The Journal of Immunology(2024)10.4049/jimmunol.2200556

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0DataRank · unranked

0 citations

Adam R. Lefferts, Eric Norman, Emilie Regner, Hanna M. Schulz, Danielle Sansone-Poe +3 more

Dysregulation of hepatic one‐carbon metabolism in classical homocystinuria: Implications of redox‐sensitive DHFR repression and tetrahydrofolate depletion for pathogenesis and treatment

The FASEB Journal(2024)10.1096/fj.202302585r

N/A

0DataRank · unranked

0 citations

Hua Jiang, Philip D. Neill, Ryan R. Chanin, K. Joseph Hurt, David J. Orlicky +4 more

MAIT cells exacerbate colonic inflammation in a genetically diverse murine model of spontaneous colitis

Mucosal Immunology(2025)10.1016/j.mucimm.2025.05.006

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0DataRank · unranked

7 citations

David J. Orlicky, Andrea Spengler, Joanne Domenico, Jared Klarquist, Cassandra L. Levens +12 more

Obese adipose tissue-derived extracellular vesicles enriched with glycolytic cargo promote colorectal cancer tumorigenesis

Cancer Letters(2025)10.1016/j.canlet.2025.218104

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0DataRank · unranked

4 citations

Shere L. Paris, Rhonda F. Souza, Joseph C. Onyiah, Christina Coughlan, David J. Orlicky +3 more

Developmentally Regulated CYP2E1 Expression Is Associated with a Fetal Pulmonary Transcriptional Response to Maternal Acetaminophen Exposure

Biomedicines(2025)10.3390/biomedicines13102446

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0DataRank · unranked

2 citations

Zhuowei Li, Lijun Zheng, Mack Solar, Maya R. Grayck, Nicole Talaba +4 more

A Single Early-Life Acetaminophen Exposure Causes Persistent Abnormalities in the Murine Lung

American Journal of Respiratory Cell and Molecular Biology(2025)10.1165/rcmb.2024-0452oc

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0DataRank · unranked

5 citations

Bradford J. Smith, Alexander Sosa, Emma Golden, William C. McCarthy, Mack Solar +8 more

Epithelial HO-1 regulates iron availability and promotes colonic tumorigenesis in a context-dependent manner

JCI Insight(2025)10.1172/jci.insight.181032

N/A

0DataRank · unranked

1 citations

Jillian Curry, Geetha Bhagavatula, Alyse Staley, Rachel E.M. Schaefer, Faiz Minhajuddin +12 more

Altered Hepatic Metabolism in Down Syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.27.656393

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0DataRank · unranked

4 citations

Brian F. Niemeyer, Neetha Paul Eduthan, Kyndal A. Schade, Katherine A. Waugh, Chrisstopher Brown +7 more

Cell Models of Castration Resistant and High Dose Testosterone-Resistant Prostate Cancer Recapitulate the Heterogeneity of Response Observed in Clinical Practice

Cancers(2025)10.3390/cancers17040593

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0DataRank · unranked

0 citations

Lih‐Jen Su, Andrew Nicklawsky, Frances Xiuyan Feng, David J. Orlicky, Joseph Petraccione +4 more

Gene-dose effect of the glutathione biosynthesis gene on ascorbate deficiency in mice

Biochemical and Biophysical Research Communications(2025)10.1016/j.bbrc.2025.151900

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0DataRank · unranked

0 citations

David J. Orlicky, Ying Chen, Reagan Strand

JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome

Cell Reports(2020)10.1016/j.celrep.2020.108407

N/A

0DataRank · unranked

67 citations

Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael P. Ludwig +11 more

Metastasis-associated wound repair promotes reciprocal activation of the lung epithelium and breast cancer metastases during outgrowth

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.23.666437

N/A

0DataRank · unranked

0 citations

Nicole S. Spoelstra, Michelle M. Williams, Kathleen O’Neill, David J. Orlicky, Jennifer A. Wagner +5 more

Bile acids modulate colonic MAdCAM-1 expression in a murine model of combined cholestasis and colitis

Mucosal Immunology(2020)10.1038/s41385-020-00347-6

N/A

0DataRank · unranked

43 citations

Colin T. Shearn, David J. Orlicky, Kayla D. Battista, Erica E. Alexeev, Ian M. Cartwright +6 more

Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet–fed mice

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.011913

N/A

0DataRank · unranked

62 citations

Yuhuan Luo, Suman Ranjit, Cen Xie, Andrew E. Libby, David J. Orlicky +15 more

Oxidized Low-Density Lipoprotein Drives Dysfunction of the Liver Lymphatic System

Cellular and Molecular Gastroenterology and Hepatology(2020)10.1016/j.jcmgh.2020.09.007

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0DataRank · unranked

47 citations

Jeffrey M. Finlon, Alyssa Goldberg, Austin E. Gillen, Petra Dahms, Rachel H. McMahan +12 more

Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer

Chemico-Biological Interactions(2020)10.1016/j.cbi.2020.109274

N/A

0DataRank · unranked

10 citations

Aikaterini Kandyliari, Wan Ying Tan, Ying Chen, David J. Orlicky, David C. Thompson +3 more

Effect of neuronal nitric oxide synthase serine-1412 phosphorylation on hypothalamic–pituitary–ovarian function and leptin response

Biology of Reproduction(2020)10.1093/biolre/ioaa025

N/A

0DataRank · unranked

10 citations

Rachael Bok, Evelyn Llerena Cari, Cari Nicholas, David J. Orlicky, Joshua Johnson +2 more

Using the novel pelvic organ prolapse histologic quantification system to identify phenotypes in uterosacral ligaments in women with pelvic organ prolapse

American Journal of Obstetrics and Gynecology(2020)10.1016/j.ajog.2020.10.040

N/A

0DataRank · unranked

23 citations

Marsha K. Guess, Elise S. Bales, Lauren G. Rascoff, Jaime Arruda, Juana Hutchinson-Colas +3 more

JAK1 inhibition blocks lethal sterile immune responses: implications for COVID-19 therapy

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.07.024455

N/A

0DataRank · unranked

15 citations

Ross Minter, Katherine A. Waugh, Paula Araya, Michael P. Ludwig, Colin Sempeck +8 more

A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age

Immunity & Ageing(2021)10.1186/s12979-021-00247-8

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0DataRank · unranked

18 citations

Kevin M. Najarro, Juliet E. Mullen, Madison T. Paul, David J. Orlicky, Holly J. Hulsebus +2 more

Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function

The Ocular Surface(2021)10.1016/j.jtos.2021.08.010

N/A

0DataRank · unranked

13 citations

Ying Chen, Emily A. Davidson, Rolando García-Milian, Jaya Prakash Golla, Nicholas Apostolopoulos +5 more

Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation

Mucosal Immunology(2021)10.1038/s41385-021-00474-8

N/A

0DataRank · unranked

13 citations

Rosemary Callahan, Shaikh M. Atif, David J. Orlicky, Ian M. Cartwright, Andrew P. Fontenot +3 more

APAP-Induced IκBβ/NFκB Signaling Drives Hepatic Il6 Expression and Associated Sinusoidal Dilation

Toxicological Sciences(2021)10.1093/toxsci/kfab131

N/A

0DataRank · unranked

9 citations

Durganili Balasubramaniyan, Lijun Zheng, Maya R. Grayck, William C. McCarthy, Robert C De Dios +5 more

Histopathological Analysis of Adrenal Glands after Simian Varicella Virus Infection

Viruses(2021)10.3390/v13071245

N/A

0DataRank · unranked

5 citations

Teresa Mescher, Rocío Belén Griggs, David J. Orlicky, Gregory K. Wilkerson, Andrew N. Bubak +6 more

Diabetes-Independent Retinal Phenotypes in an Aldose Reductase Transgenic Mouse Model

Metabolites(2021)10.3390/metabo11070450

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0DataRank · unranked

5 citations

Biehuoy Shieh, David A. Ammar, Michelle G. Pedler, David J. Orlicky, J. Mark Petrash

Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.16.464542

N/A

0DataRank · unranked

0 citations

Emily A. Davidson, Ying Chen, David J. Orlicky, David C. Thompson, Vasilis Vasiliou +1 more

The role of FXR and TGR5 in reversing and preventing progression of Western diet–induced hepatic steatosis, inflammation, and fibrosis in mice

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102530

N/A

0DataRank · unranked

57 citations

Cen Xie, Andrew E. Libby, Suman Ranjit, Jonathan Levi, Komuraiah Myakala +20 more