William G. Kaelin

Also affiliated with Brigham and Women's Hospital, Howard Hughes Medical Institute, Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Dana-Farber Brigham Cancer Center

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion”.

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

Nature Genetics(2011)10.1038/ng.936

N/A

0.838DataRank · unranked

266 citations

Michael S. Lawrence, Lear E. Brace, Alex H. Ramos, Timothy R. Dreszer, Kristian Cibulskis +37 more

Clusterin Is a Secreted Marker for a Hypoxia-Inducible Factor-Independent Function of the von Hippel-Lindau Tumor Suppressor Protein

The American Journal of Pathology(2006)10.2353/ajpath.2006.050867

N/A

0.609DataRank · unranked

57 citations

Paula Abreu-e-Lima, Yasuo Awakura, Takahiro Inoue, Toshiyuki Kamoto, Osamu Ogawa +9 more

Targeting of HIF2-driven cachexia in kidney cancer

Nature Medicine(2025)10.1038/s41591-025-04054-2

N/A

0.419DataRank · unranked

9 citations

Laura Stransky, Nikita Bhalerao, Nitin H. Shirole, Qinqin Jiang, Eddy Saad +15 more

EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer

UNC Libraries(2020)10.17615/9qfx-7w41

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0DataRank · unranked

3 citations

Xi Chen, Jing Zhang, Qing Zhang, Xingnan Zheng, Katherine M. Aird +9 more

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

UNC Libraries(2020)10.17615/wq19-7x17

N/A

0DataRank · unranked

0 citations

Adam J. Bass, Alex H. Ramos, Yujin Hoshida, Andrey Sivachenko, Trevor J. Pugh +27 more

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

UNC Libraries(2020)10.17615/emqc-jb75

N/A

0DataRank · unranked

0 citations

Kimberly J. Briggs, Agnieszka K. Witkiewicz, Shugeng Cao, Benjamin F. Cravatt, Keriann M. Backus +9 more

pVHL Acts as an Adaptor to Promote the Inhibitory Phosphorylation of the NF-κB Agonist Card9 by CK2

UNC Libraries(2020)10.17615/dnjj-4962

N/A

0DataRank · unranked

0 citations

Liang Zhang, William Y. Kim, Benjamin L. Ebert, Yan Qin, Aria F. Olumi +5 more

Targeting oncoproteins with a positive selection assay for protein degraders

Science Advances(2021)10.1126/sciadv.abd6263

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0DataRank · unranked

47 citations

Leslie Duplaquet, Benjamin L. Lampson, Adam C. Wang, Amin H. Sabet, Mette Ishoey +21 more

De Novo Pyrimidine Synthesis is a Targetable Vulnerability in IDH Mutant Glioma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470443

N/A

0DataRank · unranked

11 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +38 more

Horizontal Transfer of Histone H3 by Mammalian Cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.30.450524

N/A

0DataRank · unranked

5 citations

Hilary E. Nicholson, Matthew Z. Li, Norbert Perrimon, J Liu, William G. Kaelin +1 more

Von Hippel–Lindau disease: insights into oxygen sensing, protein degradation, and cancer

Journal of Clinical Investigation(2022)10.1172/jci162480

N/A

0DataRank · unranked

153 citations

William G. Kaelin

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

Cancer Cell(2022)10.1016/j.ccell.2022.07.011

N/A

0DataRank · unranked

131 citations

Milan R. Savani, Michael M. Levitt, Adam C. Wang, Jennifer E. Endress, Cylaina Bird +46 more

A Mesenchymal Tumor Cell State Confers Increased Dependency on the BCL-X L Anti-apoptotic Protein in Kidney Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.29.478337

N/A

0DataRank · unranked

2 citations

Smruthi Maganti, John M. Krill-Burger, Cameron Fraser, Laura Stransky, Tomas Radivoyevitch +5 more

Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation

Nature Cell Biology(2023)10.1038/s41556-023-01170-4

N/A

0DataRank · unranked

61 citations

Daichao Xu, Jianping Liu, Min Wang, Li‐Juan Duan, Min Liu +34 more

von-Hippel Lindau and Hypoxia-Inducible Factor at the Center of Renal Cell Carcinoma Biology

Hematology/Oncology Clinics of North America(2023)10.1016/j.hoc.2023.04.011

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0DataRank · unranked

23 citations

William G. Kaelin, Nitin H. Shirole

Protocol to establish a genetically engineered mouse model of IDH1-mutant astrocytoma

STAR Protocols(2023)10.1016/j.xpro.2023.102281

N/A

0DataRank · unranked

3 citations

J Lee, Adam C. Wang, Januka Khanal, Wenhua Gao, William G. Kaelin +2 more

The INDIGO trial: Precision medicine finally comes to glioma

Neuro-Oncology(2023)10.1093/neuonc/noad162

N/A

0DataRank · unranked

0 citations

William G. Kaelin, Diana D. Shi

Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB

Cell(2024)10.1016/j.cell.2024.03.022

N/A

0DataRank · unranked

48 citations

Ana S. Ramίrez, Marta Baro, Lixia He, Mudra Hegde, Vidyasagar Koduri +10 more

Induction of DEPP1 by HIF Mediates Multiple Hallmarks of Ischemic Cardiomyopathy

Circulation(2024)10.1161/circulationaha.123.066628

N/A

0DataRank · unranked

15 citations

Qinqin Jiang, Madhu Singh, Shariq Qayyum, Clara Levrero, Bradley A. Maron +2 more

Toward a CRISPR-based mouse model of Vhl -deficient clear cell kidney cancer: Initial experience and lessons learned

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2408549121

N/A

0DataRank · unranked

10 citations

Wenhua Gao, Laura S. Schmidt, Kevin Bi, C. Ricketts, Vijyendra Ramesh +28 more

HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy

Cell(2025)10.1016/j.cell.2025.01.046

N/A

0DataRank · unranked

56 citations

David A. Braun, Karl R. Clauser, Vijyendra Ramesh, Nitin H. Shirole, Joseph E. Duke-Cohan +41 more

Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer

Cancer Discovery(2025)10.1158/2159-8290.cd-24-1378

N/A

0DataRank · unranked

6 citations

Devishi Kesar, Yenarae Lee, Amy Goodale, Sudeepa Syamala, Shweta Kukreja +11 more

The SLC1A1/EAAT3 dicarboxylic amino acid transporter is an epigenetically dysregulated nutrient carrier that sustains oncogenic metabolic programs

Nature Communications(2025)10.1038/s41467-025-64983-x

N/A

0DataRank · unranked

4 citations

Pooneh Koochaki, Sayed Matar, Fatme Ghandour, Marc Machaalani, Eddy Saad +22 more

HIF2-driven PTHrP Causes Cachexia and Hypercalcemia in Kidney Cancer: Treatment with HIF2 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.09.675147

N/A

0DataRank · unranked

1 citations

Laura Stransky, Nikita Bhalerao, Nitin H. Shirole, Qinqin Jiang, Eddy Saad +15 more

Killing the Science Golden Goose

The American Journal of Medicine(2025)10.1016/j.amjmed.2025.04.003

N/A

0DataRank · unranked

0 citations

William G. Kaelin

Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle

Cell Research(2020)10.1038/s41422-020-0372-z

N/A

0DataRank · unranked

117 citations

Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long +14 more

pVHL suppresses kinase activity of Akt in a proline-hydroxylation-dependent manner

UNC Libraries(2020)10.17615/792d-1w31

N/A

0DataRank · unranked

4 citations

Jinfang Zhang, Hiroyuki Inuzuka, Xingnan Zheng, Wenjian Gan, Abhishek A. Chakraborty +13 more