Krzysztof Palczewski

Also affiliated with Robert Cizik Eye Clinic, Irvine University, University of California, Berkeley

Biochemistry, Genetics and Molecular BiologyNeuroscienceMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 67 papers. Top paper: “Scalable purification enables high-quality virus-like particles for therapeutic translation”.

Scalable purification enables high-quality virus-like particles for therapeutic translation

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110946

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0.111DataRank · unranked

1 citations

Fangyuan Gao, Samuel W. Du, Carolline Rodrigues Menezes, Jianye Zhang, Maria W. Hołubowicz +9 more

Retinoids in the visual cycle: role of the retinal G protein-coupled receptor

Journal of Lipid Research(2020)10.1194/jlr.tr120000850

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0DataRank · unranked

69 citations

Anahita Daruwalla, Susie Suh, Henri Leinonen, Krzysztof Palczewski, Elliot H. Choi

Pathways and disease-causing alterations in visual chromophore production for vertebrate vision

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.014405

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0DataRank · unranked

50 citations

Krzysztof Palczewski, Philip D. Kiser

Function of mammalian M-cones depends on the level of CRALBP in Müller cells

The Journal of General Physiology(2020)10.1085/jgp.202012675

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0DataRank · unranked

19 citations

Philip D. Kiser, Krzysztof Palczewski, Vladimir J. Kefalov, Alexander V. Kolesnikov

Epigenetic hallmarks of age-related macular degeneration are recapitulated in a photosensitive mouse model

Human Molecular Genetics(2020)10.1093/hmg/ddaa158

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0DataRank · unranked

16 citations

Les Kallestad, Thanh Hoang, Dominik Lewandowski, Zhiqian Dong, Seth Blackshaw +2 more

Single particle cryo‐EM of the complex between interphotoreceptor retinoid‐binding protein and a monoclonal antibody

The FASEB Journal(2020)10.1096/fj.202000796rr

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0DataRank · unranked

11 citations

Stefan Albiez, Sahil Gulati, Benlian Wang, Philip D. Kiser, Ľubomír Kováčik +4 more

Melanopsin Carboxy-terminus phosphorylation plasticity and bulk negative charge, not strict site specificity, achieves phototransduction deactivation

PLoS ONE(2020)10.1371/journal.pone.0228121

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10 citations

Sahil Gulati, Elelbin A. Ortiz, Krzysztof Palczewski, Phyllis R. Robinson, Juan C. Valdez‐Lopez

Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases

Bioorganic & Medicinal Chemistry Letters(2020)10.1016/j.bmcl.2020.127421

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0DataRank · unranked

2 citations

Jianye Zhang, Edward E. Korshin, Krzysztof Palczewski, Arie Gruzman, Eliav Blum

Homeostatic plasticity triggered by rod photoreceptor degenerative disease is associated with maintenance of sensitive night vision

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.121673

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0DataRank · unranked

0 citations

Nguyen C. Pham, Taylor Boyd, Johanes Santoso, Krzysztof Palczewski, Frans Vinberg +1 more

Determinants shaping the nanoscale architecture of the mouse rod outer segment

eLife(2021)10.7554/elife.72817

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0DataRank · unranked

51 citations

Julia Mahamid, Sanae S Imanishi, Jürgen M Plitzko, Krzysztof Palczewski, Wolfgang Baumeister +1 more

An inducible Cre mouse for studying roles of the RPE in retinal physiology and disease

JCI Insight(2021)10.1172/jci.insight.146604

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0DataRank · unranked

36 citations

Susie Suh, David E. Einstein, Henri Leinonen, Zhiqian Dong, Sriganesh Ramachandra Rao +7 more

In vivo imaging of the human eye using a 2-photon-excited fluorescence scanning laser ophthalmoscope

Journal of Clinical Investigation(2021)10.1172/jci154218

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44 citations

Grazyna Palczewska, Slawomir Tomczewski, Jadwiga Milkiewicz, Piotr Kasprzycki, Dorota Stachowiak +11 more

Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition

The Journal of Cell Biology(2021)10.1083/jcb.202101063

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0DataRank · unranked

40 citations

Avery E. Sears, Antônio F. M. Pinto, Elliot H. Choi, Shirin Kahremany, Fangyuan Gao +11 more

MicroRNA regulation of critical retinal pigment epithelial functions

Trends in Neurosciences(2021)10.1016/j.tins.2021.10.008

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30 citations

Krzysztof Palczewski, Samuel W. Du

Structural evidence for visual arrestin priming via complexation of phosphoinositols

Structure(2021)10.1016/j.str.2021.10.002

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0DataRank · unranked

27 citations

Jennings Luu, Kyumhyuk Kim, David Furkert, Kiyoung Jang, Joerg Reichenwallner +10 more

A large animal model of RDH5-associated retinopathy recapitulates important features of the human phenotype

Human Molecular Genetics(2021)10.1093/hmg/ddab316

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18 citations

Anahita Daruwalla, Samantha R. De Silva, Paige A. Winkler, Kelian Sun, Nate Pasmanter +13 more

Theoretical Study of the Photoisomerization Mechanism of All-Trans-Retinyl Acetate

The Journal of Physical Chemistry A(2021)10.1021/acs.jpca.1c05533

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4 citations

Krzysztof Palczewski, Adam Kubas, Michał A. Kochman

Identification of small-molecule allosteric modulators that act as enhancers/disrupters of rhodopsin oligomerization

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101401

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7 citations

Albert Kemp, Frans Vinberg, Krzysztof Palczewski, Tamar Getter

Determinants shaping the nanoscale architecture of the mouse rod outer segment

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.18.456753

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0DataRank · unranked

4 citations

Julia Mahamid, Sanae S Imanishi, Jürgen M Plitzko, Krzysztof Palczewski, Wolfgang Baumeister +1 more

Dissecting lipid contents in the distinct regions of native retinal rod disk membranes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.11.426250

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0DataRank · unranked

1 citations

Avery E. Sears, Antônio F. M. Pinto, Elliot H. Choi, Shirin Kahremany, Hui Jin +9 more

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

Cell(2022)10.1016/j.cell.2021.12.021

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0DataRank · unranked

644 citations

Aditya Raguram, Susie Suh, Samuel W. Du, Jessie R. Davis, Elliot H. Choi +9 more

In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration

Nature Communications(2022)10.1038/s41467-022-29490-3

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0DataRank · unranked

94 citations

Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao +11 more

Capturing a rhodopsin receptor signalling cascade across a native membrane

Nature(2022)10.1038/s41586-022-04547-x

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0DataRank · unranked

86 citations

Tamar Getter, David Salom, Di Wu, Daniel Quetschlich, Dror S. Chorev +3 more

Precision genome editing in the eye

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2210104119

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0DataRank · unranked

53 citations

Elliot H. Choi, Aditya Raguram, David R. Liu, Krzysztof Palczewski, Susie Suh

Inhibition of ceramide accumulation in AdipoR1–/– mice increases photoreceptor survival and improves vision

JCI Insight(2022)10.1172/jci.insight.156301

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0DataRank · unranked

47 citations

Andrzej T. Foik, Roman Šmidák, Elliot H. Choi, Jianye Zhang, Thanh Hoang +17 more

Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles

Molecular Therapy — Nucleic Acids(2022)10.1016/j.omtn.2022.08.026

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0DataRank · unranked

31 citations

Wenyu Sun, Songqi Gao, Jonathan Lehrer, Amirreza Naderi, Cheng Wei +8 more

Structural view of G protein-coupled receptor signaling in the retinal rod outer segment

Trends in Biochemical Sciences(2022)10.1016/j.tibs.2022.08.010

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27 citations

Krzysztof Palczewski, Sahil Gulati

Chromophore hydrolysis and release from photoactivated rhodopsin in native membranes

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213911119

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0DataRank · unranked

24 citations

David Salom, Michał A. Kochman, Adam Kubas, Philip D. Kiser, Krzysztof Palczewski +1 more

VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy

Journal of Translational Medicine(2022)10.1186/s12967-021-03186-6

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0DataRank · unranked

22 citations

Lan Weiss, Henri Leinonen, Alyaa Shmara, Hong Yin, Timothy Ton +9 more

Visual System Hyperexcitability and Compromised V1 Receptive Field Properties in Early-Stage Retinitis Pigmentosa in Mice

eNeuro(2022)10.1523/eneuro.0107-22.2022

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0DataRank · unranked

15 citations

David C. Lyon, Krzysztof Palczewski, Andrzej T. Foik, Henri Leinonen

Ultrafast spectra and kinetics of human green-cone visual pigment at room temperature

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2214276120

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0DataRank · unranked

10 citations

David Salom, Krzysztof Palczewski, P. M. Rentzepis, Dinesh Dhankhar

Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration

Current Biology(2022)10.1016/j.cub.2022.09.005

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0DataRank · unranked

5 citations

Henri Leinonen, Taylor Nakayama, Julia Tomasello, Jianye Zhang, Jack Zeitoun +7 more

Stabilization of Meta‐I Rhodopsin Conformation by a Nanobody

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r2572

N/A

0DataRank · unranked

0 citations

Arum Wu, Christopher L. Sander, Els Pardon, Jan Steyaert, Philip D. Kiser +2 more

Genome editing in the treatment of ocular diseases

Experimental & Molecular Medicine(2023)10.1038/s12276-023-01057-2

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0DataRank · unranked

44 citations

Susie Suh, Avery E. Sears, Rafał Hołubowicz, Sanjay Kedhar, Andrew Browne +2 more

Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia

Cell Reports(2023)10.1016/j.celrep.2023.112982

N/A

0DataRank · unranked

42 citations

Alexander V. Kolesnikov, John D. Hong, Elliot H. Choi, Jennings Luu, Grażyna Palczewska +9 more

Genome editing, a superior therapy for inherited retinal diseases

Vision Research(2023)10.1016/j.visres.2023.108192

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0DataRank · unranked

37 citations

Samuel W. Du, Krzysztof Palczewski, Alexander L. Yan

Structural basis for the allosteric modulation of rhodopsin by nanobody binding to its extracellular domain

Nature Communications(2023)10.1038/s41467-023-40911-9

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0DataRank · unranked

25 citations

David Salom, John D. Hong, Aleksander Tworak, Kohei Watanabe, Els Pardon +6 more

Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2221045120

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18 citations

Aicha Saadane, Henri Leinonen, Elliot H. Choi, Fangyuan Gao, Dominik Lewandowski +16 more

Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2314698120

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0DataRank · unranked

12 citations

Dominik Lewandowski, Zhiqian Dong, Grażyna Palczewska, Jianye Zhang, Katarzyna Kordecka +6 more

A short story on how chromophore is hydrolyzed from rhodopsin for recycling

BioEssays(2023)10.1002/bies.202300068

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0DataRank · unranked

10 citations

Krzysztof Palczewski, John D. Hong

Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice

Journal of Alzheimer s Disease(2023)10.3233/jad-231102

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0DataRank · unranked

10 citations

Henri Leinonen, Evan J. Wang, Mao Ding, George Perry, Krzysztof Palczewski +2 more

In vivo imaging of the human retina using a two-photon excited fluorescence ophthalmoscope

STAR Protocols(2023)10.1016/j.xpro.2023.102225

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0DataRank · unranked

9 citations

Slawomir Tomczewski, Michał Dąbrowski, Katarzyna Komar, Jadwiga Milkiewicz, Grażyna Palczewska +3 more

Saving eyesight, one gene at a time

Trends in Molecular Medicine(2023)10.1016/j.molmed.2023.04.008

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0DataRank · unranked

1 citations

Krzysztof Palczewski, Rafał Hołubowicz

Investigating the Role of RhodopsinF45LMutation in Mouse Rod Photoreceptor Signaling and Survival

eNeuro(2023)10.1523/eneuro.0330-22.2023

N/A

0DataRank · unranked

2 citations

Alexander V. Kolesnikov, Tae Jun Lee, David Salom, Krzysztof Palczewski, Vladimir J. Kefalov +1 more

Identification of conserved gene expression programs activated in multiple modes of torpor across vertebrate clades

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.29.569284

N/A

0DataRank · unranked

0 citations

Natasha Vega, Veronica F. Busa, Ben Sajdak, Les Kallestad, Dana K. Merriman +4 more

Engineered virus-like particles for transient delivery of prime editor ribonucleoprotein complexes in vivo

Nature Biotechnology(2024)10.1038/s41587-023-02078-y

N/A

0DataRank · unranked

244 citations

Aditya Raguram, Samuel W. Du, Samagya Banskota, Jessie R. Davis, Gregory A. Newby +4 more

Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulations

Nature Biomedical Engineering(2024)10.1038/s41551-024-01296-2

N/A

0DataRank · unranked

81 citations

Samuel W. Du, Jiin Felgner, Roman Šmidák, Elliot H. Choi, Grażyna Palczewska +19 more

In vivo photoreceptor base editing ameliorates rhodopsin-E150K autosomal-recessive retinitis pigmentosa in mice

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2416827121

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0DataRank · unranked

15 citations

Gregory A. Newby, David Salom, Fangyuan Gao, Carolline Rodrigues Menezes, Susie Suh +5 more

Retinal Proteome Profiling of Inherited Retinal Degeneration Across Three Different Mouse Models Suggests Common Drug Targets in Retinitis Pigmentosa

Molecular & Cellular Proteomics(2024)10.1016/j.mcpro.2024.100855

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0DataRank · unranked

16 citations

Fangyuan Gao, Danielle L. Peters, Katri Vainionpää, Ning Zhibin, Dorota Skowronska‐Krawczyk +4 more

Dominant role for pigment epithelial CRALBP in supplying visual chromophore to photoreceptors

Cell Reports(2024)10.1016/j.celrep.2024.114143

N/A

0DataRank · unranked

13 citations

Alexander V. Kolesnikov, Dominik Lewandowski, Jianying Kiser, Maximilian Halabi, David E. Einstein +5 more

The Impact of Nanobodies on G Protein–Coupled Receptor Structural Biology and Their Potential as Therapeutic Agents

Molecular Pharmacology(2024)10.1124/molpharm.124.000974

N/A

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13 citations

Arum Wu, Chang C. Liu, Krzysztof Palczewski, David Salom

Retinylidene chromophore hydrolysis from mammalian visual and non-visual opsins

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.105678

N/A

0DataRank · unranked

10 citations

David Salom, Elliot H. Choi, Samuel W. Du, Aleksander Tworak, Roman Šmidák +6 more

Restoring retinal polyunsaturated fatty acid balance and retina function by targeting ceramide in AdipoR1-deficient mice

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107291

N/A

0DataRank · unranked

9 citations

Fangyuan Gao, Sanae S Imanishi, Aleksander Tworak, Marco Bassetto, Zhiqian Dong +7 more

Conditional deletion of miR-204 and miR-211 in murine retinal pigment epithelium results in retinal degeneration

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107344

N/A

0DataRank · unranked

4 citations

Ravikiran Komirisetty, Dominik Lewandowski, Elliot H. Choi, Damian Panas, Susie Suh +4 more

The multifaceted roles of retinoids in eye development, vision, and retinal degenerative diseases

Current topics in developmental biology/Current Topics in Developmental Biology(2024)10.1016/bs.ctdb.2024.10.003

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0DataRank · unranked

4 citations

Krzysztof Palczewski, Zachary J Engfer

Identification of shared gene expression programs activated in multiple modes of torpor across vertebrate clades

Scientific Reports(2024)10.1038/s41598-024-74324-5

N/A

0DataRank · unranked

2 citations

Natasha Vega, Veronica F. Busa, Ben Sajdak, Les Kallestad, Dana K. Merriman +4 more

Engineered nucleocytosolic vehicles for loading of programmable editors

Cell(2025)10.1016/j.cell.2025.03.015

N/A

0DataRank · unranked

43 citations

Niklas Armbrust, Emily Steinmaßl, Samuel W. Du, Sebastian Schmidt, E. Binder +23 more

Photopic flicker optoretinography captures the light-driven length modulation of photoreceptors during phototransduction

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2421722122

N/A

0DataRank · unranked

17 citations

Andrea Curatolo, Andrzej T. Foik, Piotr Węgrzyn, Bartłomiej Bałamut, Maciej Wielgo +8 more

Impaired axonal transport contributes to neurodegeneration in a Cre-inducible mouse model of myocilin-associated glaucoma

JCI Insight(2025)10.1172/jci.insight.188710

N/A

0DataRank · unranked

7 citations

Ramesh B. Kasetti, Yogapriya Sundaresan, Linya Li, Sam Yacoub, J. Cameron Millar +6 more

MFRP is a molecular hub that organizes the apical membrane of RPE cells by engaging in interactions with specific proteins and lipids

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2425523122

N/A

0DataRank · unranked

4 citations

Roman Šmidák, Carolline Rodrigues Menezes, Samuel W. Du, Susie Suh, Elliot H. Choi +12 more

TIGER: A tdTomato in vivo genome-editing reporter mouse for investigating precision-editor delivery approaches

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2506257122

N/A

0DataRank · unranked

4 citations

Grażyna Palczewska, Zhiqian Dong, Julie C. Lauterborn, Balasankara Reddy Kaipa, Alexander L. Yan +8 more

CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3

Open Biology(2025)10.1098/rsob.240180

N/A

0DataRank · unranked

2 citations

Luca Gessa, Nelam Kumar, Matyáš Pinkas, Mariusz Czarnocki‐Cieciura, Krzysztof Palczewski +3 more

Retinol tracing within murine neural retina reveals cell type–specific retinol transport and distribution

Journal of Clinical Investigation(2025)10.1172/jci198648

N/A

0DataRank · unranked

1 citations

Grażyna Palczewska, Samuel W. Du, Jianye Zhang, Zhiqian Dong, Carolline Rodrigues Menezes +8 more

Presynaptic Changes in Mouse Rod Photoreceptors During Early Retinitis Pigmentosa

Investigative Ophthalmology & Visual Science(2025)10.1167/iovs.66.15.4

N/A

0DataRank · unranked

1 citations

Lee Sturgis, Ahmed B. Montaser, Marcin Tabaka, Elliot H. Choi, Deepa Mathew +6 more

Integrin Trafficking, Fibronectin Architecture, and Glomerular Injury upon Adiponectin Receptor 1 Depletion

Journal of the American Society of Nephrology(2025)10.1681/asn.0000000611

N/A

0DataRank · unranked

2 citations

Constanze Schmotz, Dominik Lewandowski, Annika Hau, Leena Saikko, Eero Lehtonen +13 more

Restoration of visual function in adult mice with an inherited retinal disease via adenine base editing

Nature Biomedical Engineering(2020)10.1038/s41551-020-00632-6

N/A

0DataRank · unranked

168 citations

Elliot H. Choi, Henri Leinonen, Andrzej T. Foik, Gregory A. Newby, Wei-Hsi Yeh +6 more

Structure and self-association of Arrestin-1

Journal of Structural Biology(2025)10.1016/j.jsb.2025.108173

N/A

0DataRank · unranked

0 citations

Krzysztof Palczewski, David Salom