Erik J. Sontheimer

University of Massachusetts Chan Medical School

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 35 papers. Top paper: “5′-Modifications improve potency and efficacy of DNA donors for precision genome editing”.

5′-Modifications improve potency and efficacy of DNA donors for precision genome editing

eLife(2021)10.7554/elife.72216

N/A

2.1DataRank · unranked

72 citations

Zexiang Chen, Aamir Mir, Gregoriy A. Dokshin, Pranathi M. Krishnamurthy, Yeonsoo Yoon +15 more

Template-jumping prime editing enables large insertion and exon rewriting in vivo

Nature Communications(2023)10.1038/s41467-023-39137-6

N/A

0.628DataRank · unranked

65 citations

Bin Liu, Xiaolong Dong, Nicholas Gaston, Erik J. Sontheimer, Wen Xue +1 more

Self-delivering, chemically modified CRISPR RNAs for AAV co-delivery and genome editing in vivo

Nucleic Acids Research(2023)10.1093/nar/gkad1125

N/A

0.563DataRank · unranked

17 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +13 more

Domain-inlaid Nme2Cas9 adenine base editors with improved activity and targeting scope

Nature Communications(2024)10.1038/s41467-024-45763-5

N/A

0.517DataRank · unranked

15 citations

Han Zhang, Xiaolong Dong, Haoyang Cheng, Nicholas Gaston, Hailey Feinzig +7 more

CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures

Molecular Cell(2020)10.1016/j.molcel.2020.02.015

N/A

0DataRank · unranked

1 citations

Erik J. Sontheimer, Rodolphe Barrangou

Publisher Correction: An engineered ScCas9 with broad PAM range and high specificity and activity

Nature Biotechnology(2020)10.1038/s41587-020-0604-2

N/A

0DataRank · unranked

5 citations

Noah Jakimo, Jooyoung Lee, Nadia Amrani, Tomás Rodríguez, Sabrina Koseki +6 more

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

Nature Communications(2021)10.1038/s41467-021-22295-w

N/A

0DataRank · unranked

281 citations

Shun‐Qing Liang, Chunwei Zheng, Esther Mintzer, Yan Zhao, Karthikeyan Ponnienselvan +7 more

The NIH Somatic Cell Genome Editing program

Nature(2021)10.1038/s41586-021-03191-1

N/A

0DataRank · unranked

132 citations

Erik J. Sontheimer, Philip J. Brooks, Melinda R. Dwinell, Charles A. Gersbach, David R. Liu +70 more

Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo

Nature Communications(2021)10.1038/s41467-021-26518-y

N/A

0DataRank · unranked

116 citations

Phillip W.L. Tai, Aamir Mir, Nida Javeed, Jiaming Wang, Tomás Rodríguez +15 more

CRISPR-enhanced human adipocyte browning as cell therapy for metabolic disease

Nature Communications(2021)10.1038/s41467-021-27190-y

N/A

0DataRank · unranked

90 citations

Sarah M. Nicoloro, Tiffany DeSouza, Javier Solivan-Rivera, Anand Desai, Lawrence M. Lifshitz +18 more

Orthogonal CRISPR-Cas tools for genome editing, inhibition, and CRISPR recording in zebrafish embryos

Genetics(2021)10.1093/genetics/iyab196

N/A

0DataRank · unranked

24 citations

Shengzhou Wang, Kimberly T. Truong, Evan P. Drage, Sahar N. Kanishka, Marissa A. Higbee +5 more

Adenine Base Editing in vivo with a Single Adeno-Associated Virus Vector

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.13.472434

N/A

0DataRank · unranked

1 citations

Nathan Bamidele, Pengpeng Liu, Ogooluwa Ojelabi, Xin D. Gao, Tomás Rodríguez +7 more

A split prime editor with untethered reverse transcriptase and circular RNA template

Nature Biotechnology(2022)10.1038/s41587-022-01255-9

N/A

0DataRank · unranked

169 citations

Xiaolong Dong, Haoyang Cheng, Chunwei Zheng, Zexiang Chen, Tomás Rodríguez +4 more

Adenine Base Editing In Vivo with a Single Adeno-Associated Virus Vector

GEN Biotechnology(2022)10.1089/genbio.2022.0015

N/A

0DataRank · unranked

68 citations

Nathan Bamidele, Pengpeng Liu, Ogooluwa Ojelabi, Xin D. Gao, Tomás Rodríguez +9 more

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

Nature Communications(2022)10.1038/s41467-022-28135-9

N/A

0DataRank · unranked

58 citations

Pengpeng Liu, Jordan L. Smith, Esther Mintzer, Stacy A. Maitland, Xiaolong Dong +9 more

Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts

Nucleic Acids Research(2022)10.1093/nar/gkac630

N/A

0DataRank · unranked

29 citations

Io Long Chan, Yuming Cao, Alisha M. Gruntman, Jonathan Lee, Jacquelyn Sousa +17 more

Multiomics characterization of mouse hepatoblastoma identifies yes‐associated protein 1 target genes

Hepatology(2022)10.1002/hep.32713

N/A

0DataRank · unranked

2 citations

Suet‐Yan Kwan, Jordan L. Smith, Sina Dadafarin, Chern‐Horng Wu, Erik J. Sontheimer +2 more

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

Nature Methods(2023)10.1038/s41592-023-01859-2

N/A

0DataRank · unranked

77 citations

Pengpeng Liu, Karthikeyan Ponnienselvan, Sneha Suresh, Zexiang Chen, Christian Kramme +6 more

Targeted genome editing with a DNA-dependent DNA polymerase and exogenous DNA-containing templates

Nature Biotechnology(2023)10.1038/s41587-023-01947-w

N/A

0DataRank · unranked

59 citations

Xiaolong Dong, Chunwei Zheng, David G. Keener, Zexiang Chen, Haoyang Cheng +4 more

PAM-flexible genome editing with an engineered chimeric Cas9

Nature Communications(2023)10.1038/s41467-023-41829-y

N/A

0DataRank · unranked

57 citations

Sabrina Koseki, Rachel A. Silverstein, Nadia Amrani, Christina Peng, Christian Kramme +17 more

CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes

Nucleic Acids Research(2023)10.1093/nar/gkad890

N/A

0DataRank · unranked

38 citations

Marena Trinidad, Daniel Bellieny‐Rabelo, Elaine Zhang, Hannah Karp, Petr Skopintsev +48 more

In Vivo Prime Editing by Lipid Nanoparticle Co-Delivery of Chemically Modified pegRNA and Prime Editor mRNA

GEN Biotechnology(2023)10.1089/genbio.2023.0045

N/A

0DataRank · unranked

33 citations

Karen Kelly, Haoyang Cheng, Xiaolong Dong, Adam K. Hedger, Li Li +3 more

A Fluorescent Reporter Mouse for In Vivo Assessment of Genome Editing with Diverse Cas Nucleases and Prime Editors

The CRISPR Journal(2023)10.1089/crispr.2023.0048

N/A

0DataRank · unranked

7 citations

Suet‐Yan Kwan, Aamir Mir, Max D. Hazeltine, Minwook Shin, Shun‐Qing Liang +11 more

CasPEDIA Database: A Functional Classification System for Class 2 CRISPR-Cas Enzymes

(2023)10.32942/x2c31f

N/A

0DataRank · unranked

6 citations

Marena Trinidad, Daniel Bellieny‐Rabelo, Elaine Zhang, Hannah Karp, Petr Skopintsev +47 more

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.20.533459

N/A

0DataRank · unranked

1 citations

Karen Kelly, Jonathan Lee, Dimas Echeverria, David Cooper, Rebecca Panwala +11 more

Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.14.536905

N/A

0DataRank · unranked

0 citations

Han Zhang, Xiaolong Dong, Nicholas Gaston, Haoyang Cheng, Karen Kelly +5 more

Increasing intracellular dNTP levels improves prime editing efficiency

Nature Biotechnology(2024)10.1038/s41587-024-02405-x

N/A

0DataRank · unranked

29 citations

Karthikeyan Ponnienselvan, Thomas Nyalile, Sarah Oikemus, Anya T. Joynt, Sukanya Iyer +18 more

PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.12.603173

N/A

0DataRank · unranked

1 citations

Leonid Yurkovetskiy, Karthika Nagalekshmi, Oscar Lam, Eva Jazbec, Stacy A. Maitland +4 more

Absolute quantification of mammalian microRNAs for therapeutic RNA cleavage and detargeting

RNA(2025)10.1261/rna.080566.125

N/A

0DataRank · unranked

5 citations

Jiayi Wang, Haiying Zheng, Jennifer A. Broderick, Nandagopal Ajaykumar, Mina Zamani +10 more

A compact base editor rescues AATD-associated liver and lung disease in mouse models

Molecular Therapy(2025)10.1016/j.ymthe.2025.08.040

N/A

0DataRank · unranked

3 citations

Nathan Bamidele, Debora Pires-Ferreira, Chunwei Zheng, April Destefano, Haoyang Cheng +9 more

Anti-CRISPRs: Protein Inhibitors of CRISPR-Cas Systems

Annual Review of Biochemistry(2020)10.1146/annurev-biochem-011420-111224

N/A

0DataRank · unranked

166 citations

Wangting Lu, Sabrina Y. Stanley, Jingrui Wang, Marios Mejdani, Chantel N. Trost +4 more

A Compact Base Editor Rescues AATD-associated Liver and Lung Disease in Mouse Models

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.07.652636

N/A

0DataRank · unranked

0 citations

Nathan Bamidele, Debora Pires-Ferreira, April Destefano, Qiushi Tang, Yueying Cao +5 more

An engineered ScCas9 with broad PAM range and high specificity and activity

Nature Biotechnology(2020)10.1038/s41587-020-0517-0

N/A

0DataRank · unranked

139 citations

Noah Jakimo, Jooyoung Lee, Nadia Amrani, Tomás Rodríguez, Sabrina Koseki +6 more

A Cas9 with PAM recognition for adenine dinucleotides

Nature Communications(2020)10.1038/s41467-020-16117-8

N/A

0DataRank · unranked

119 citations

Jooyoung Lee, Lisa Nip, Sabrina Koseki, Emma Tysinger, Erik J. Sontheimer +3 more

YAP1 Withdrawal in Hepatoblastoma Drives Therapeutic Differentiation of Tumor Cells to Functional Hepatocyte‐Like Cells

Hepatology(2020)10.1002/hep.31389

N/A

0DataRank · unranked

22 citations

Tomás Rodríguez, Haiwei Mou, Suet‐Yan Kwan, Henry Pratt, Xiao‐Ou Zhang +10 more