Matthieu Schapira

Also affiliated with University of Toronto, Princess Margaret Cancer Centre, Health Net, Structural Genomics Consortium

Biochemistry, Genetics and Molecular BiologyComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Papers

Driven by 37 papers — median percentile 0. Top paper: “Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells”.

Regulated Translation Initiation Controls Stress-Induced Gene Expression in Mammalian Cells

Molecular Cell(2000)10.1016/s1097-2765(00)00108-8

N/A

15.5DataRank · unranked

3281 citations

Isabel Novoa, Yuhong Zhang, Huiqing Zeng, Ron Wek, Matthieu Schapira +2 more

Application of established computational techniques to identify potential SARS-CoV-2 Nsp14-MTase inhibitors in low data regimes

Digital Discovery(2024)10.1039/d4dd00006d

N/A

0.345DataRank · unranked

9 citations

Matthew F. D. Hurley, Fengling Li, Eva Konkoľová, Martin Klíma, Jana Trylčová +21 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00535

N/A

0.292DataRank · unranked

6 citations

Madhushika Silva, Ayaz Ahmad, Oscar E. A. Arce, Roly J. Armstrong, Cheryl Arrowsmith +105 more

Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.05.433782

N/A

0.208DataRank · unranked

3 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +29 more

Drug Discovery in Low Data Regimes: Leveraging a Computational Pipeline for the Discovery of Novel SARS-CoV-2 Nsp14-MTase Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.03.560722

N/A

0.165DataRank · unranked

2 citations

Matthew F. D. Hurley, Fengling Li, Eva Konkoľová, Martin Klíma, Jana Trylčová +21 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq-v3

N/A

0.165DataRank · unranked

2 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

CACHE Challenge #2: Targeting the RNA Site of the SARS-CoV-2 Helicase Nsp13

ChemRxiv(2025)10.26434/chemrxiv-2025-8f0rq

N/A

0.150DataRank · unranked

1 citations

Madhushika Silva, Abd Al‐Aziz A. Abu‐Saleh, Ayaz Ahmad, Jesus Antonio Alvarado-Huayhuaz, Oscar E. A. Arce +104 more

A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

Nature Chemical Biology(2021)10.1038/s41589-021-00898-0

N/A

0DataRank · unranked

109 citations

Ronan P. Hanley, Renato Ferreira de Freitas, Abdellah Allali‐Hassani, Mengqi Zhou, Naimee Mehta +35 more

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro Using SAM Competitive Inhibitors Guides Developing Selective Bisubstrate Inhibitors

SLAS DISCOVERY(2021)10.1177/24725552211026261

N/A

0DataRank · unranked

89 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

Communications Biology(2021)10.1038/s42003-021-02895-4

N/A

0DataRank · unranked

59 citations

Justin C. Deme, Johannes F. Hevler, Sem Tamara, Alexander Lemak, Jeffrey P. Cantle +15 more

A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c02160

N/A

0DataRank · unranked

27 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halabelian, Irene Chau, Mohammad S. Eram +22 more

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

UCL Discovery (University College London)(2021)10.33774/chemrxiv-2021-rzq4n

N/A

0DataRank · unranked

13 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

Probing the SAM Binding Site of SARS-CoV-2 nsp14 in vitro Using SAM Competitive Inhibitors Guides Developing Selective bi-substrate Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.424337

N/A

0DataRank · unranked

11 citations

Matthieu Schapira, Sumera Perveen, Aliakbar Khalili Yazdi, Fengling Li, Irene Chau +15 more

HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438217

N/A

0DataRank · unranked

3 citations

Justin C. Deme, Johannes F. Hevler, Sem Tamara, Alexander Lemak, Jeffrey P. Cantle +12 more

CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding

ChemRxiv(2021)10.26434/chemrxiv-2021-rzq4n

N/A

0DataRank · unranked

0 citations

Rima Al‐awar, Rommie E. Amaro, C.H. Arrowsmith, Hátylas Azevedo, Robert A. Batey +34 more

Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00314

N/A

0DataRank · unranked

10 citations

Ivan Franzoni, Mandeep Mann, Magdalena M. Szewczyk, Bijan Mirabi, Renato Ferreira de Freitas +14 more

A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening

ChemRxiv(2023)10.26434/chemrxiv-2023-jgbgv

N/A

0DataRank · unranked

3 citations

Grace K. Shimokura, F. G. West, Tabitha E. Wood, Robert A Batey, John J. Irwin +2 more

Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.21.525740

N/A

0DataRank · unranked

1 citations

Ivan Franzoni, Mandeep Mann, Magdalena M. Szewczyk, Bijan Mirabi, Dominic D. G. Owens +13 more

Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.25.398586

N/A

0DataRank · unranked

5 citations

Yanli Liu, Magdalena M. Szewczyk, Naimee Mehta, Fengling Li, David McLeod +14 more

A data science roadmap for open science organizations engaged in early-stage drug discovery

Nature Communications(2024)10.1038/s41467-024-49777-x

N/A

0DataRank · unranked

23 citations

Aled Edwards, Ola Engkvist, Judith Günther, Matthew Hartley, David G. Hulcoop +19 more

A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c02010

N/A

0DataRank · unranked

22 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +67 more

The Pan-Canadian Chemical Library: A Mechanism to Open Academic Chemistry to High-Throughput Virtual Screening

Scientific Data(2024)10.1038/s41597-024-03443-5

N/A

0DataRank · unranked

10 citations

Grace K. Shimokura, F. G. West, Tabitha E. Wood, Robert A. Batey, John J. Irwin +2 more

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson’s Disease associated protein

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.18.603797

N/A

0DataRank · unranked

5 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +90 more

A resource to enable chemical biology and drug discovery of WDR Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.03.583197

Top 100%

0DataRank

Top 100%0 citations

Fengling Li, Magda Szewczyk, Almagul Seitova, P. Loppnau, Hong Zeng +65 more

Structural Chemistry of Helicase Inhibition

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.4c01909

N/A

0DataRank · unranked

24 citations

Timothy M. Willson, Matthieu Schapira, Lakshi Selvaratnam

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

Chemical Science(2025)10.1039/d4sc07532c

N/A

0DataRank · unranked

5 citations

Marta Glavatskikh, Xiaowen Wang, Antonio Jesús Lara Ordóñez, Fengling Li, Irene Chau +17 more

Enantioselective protein affinity selection mass spectrometry (E-ASMS)

Nature Communications(2025)10.1038/s41467-025-67403-2

N/A

0DataRank · unranked

1 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +34 more

Active Learning-Guided Hit Optimization for the Leucine-Rich Repeat Kinase 2 WDR Domain Based on In Silico Ligand-Binding Affinities

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c00588

N/A

0DataRank · unranked

1 citations

Evgeny Gutkin, Francesco Gentile, Fuqiang Ban, S. Benjamin Koby, Fengling Li +19 more

Enantioselective Protein Affinity Selection Mass Spectrometry (E-ASMS)

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.17.633682

N/A

0DataRank · unranked

7 citations

Jianxian Sun, Shabbir Ahmad, Diwen Yang, Fengling Li, U Hang Chan +33 more

Structure-based discovery of inhibitors of Mac1 domain of nonstructural protein-3 of SARS-CoV-2 by machine learning-augmented screening of chemical space

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.05.674529

N/A

0DataRank · unranked

2 citations

Rahul Ravichandran, G.J. Correy, Oleksandra Herasymenko, Madhushika Silva, Suzanne Ackloo +11 more

Functionally active modulators targeting the LRRK2 WD40 repeat domain identified by FRASE-bot in CACHE Challenge #1

UNC Libraries(2025)10.17615/qcft-3792

N/A

0DataRank · unranked

0 citations

Suzanne Ackloo, C. Arrowsmith, Alma Seitova, Li F, Albina Bolotokova +17 more

Structural Chemistry of Helicase Inhibition

UNC Libraries(2025)10.17615/j68m-aa83

N/A

0DataRank · unranked

0 citations

Timothy M. Willson, Lakshi Selvaratnam, Matthieu Schapira

CACHE Challenge #3: Targeting the Nsp3 Macrodomain of SARS-CoV-2

ChemRxiv(2025)10.26434/chemrxiv-2025-d1v7v

N/A

0DataRank · unranked

0 citations

Madhushika Silva, G.J. Correy, Abd Al‐Aziz A. Abu‐Saleh, Suzanne Ackloo, C. Arrowsmith +74 more

CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson’s Disease Associated Protein

Journal of Chemical Information and Modeling(2024)10.1021/acs.jcim.4c01267

N/A

0DataRank · unranked

26 citations

Suzanne Ackloo, C.H. Arrowsmith, Fuqiang Ban, Christopher Barden, Hartmut Beck +91 more

A First-in-class, Highly Selective and Cell-active Allosteric Inhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.412569

N/A

0DataRank · unranked

1 citations

Fengling Li, Magdalena M. Szewczyk, Levon Halebelian, Irene Chau, Mohammad S. Eram +19 more

Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin

UNC Libraries(2020)10.17615/95jj-mm18

N/A

0DataRank · unranked

0 citations

Brian D. Strahl, P. Savitsky, Hans Friedrichsen, T. Krojer, S. Picaud +11 more

A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

UNC Libraries(2020)10.17615/s278-v194

N/A

0DataRank · unranked

0 citations

Luo Xiao, Magdalena M. Szewczyk, Masoud Vedadi, Aiping Dong, David Smil +24 more

Matthieu Schapira

Indexed papers

Top data-sharing exemplar

Papers