Hidde L. Ploegh

Also affiliated with Harvard University, Leiden University Medical Center, Boston Children's Museum

Immunology and MicrobiologyMedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 6%percentile

0.222Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Mapping Alzheimer’s Molecular Pathologies in Large-Scale Connectomics Data: A Publicly Accessible Correlative Microscopy Resource

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.24.563674

Top 62%

0.222DataRank

Top 62%3 citations

Peter H. Li, Shuohong Wang, Tim Blakely, Sneha Aggarwal, Bhavika Gopalani +16 more

Papers

Driven by 49 papers — median percentile 38. Top paper: “Exploring cellular biochemistry with nanobodies”.

Exploring cellular biochemistry with nanobodies

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.012960

N/A

2.3DataRank · unranked

102 citations

Thibault J. Harmand, Charlotte Wijne, Thomas Schwartz, Hidde L. Ploegh, Ross W. Cheloha

Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex

Nature Communications(2024)10.1038/s41467-024-50411-z

N/A

0.355DataRank · unranked

8 citations

Xiaotang Lu, Peter H. Li, Shuohong Wang, Richard Schalek, Yaron Meirovitch +16 more

Mapping Alzheimer’s Molecular Pathologies in Large-Scale Connectomics Data: A Publicly Accessible Correlative Microscopy Resource

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.24.563674

Top 62%

0.222DataRank

Top 62%3 citations

Peter H. Li, Shuohong Wang, Tim Blakely, Sneha Aggarwal, Bhavika Gopalani +16 more

Identification and characterization of nanobodies specific for the human ubiquitin–like ISG15 protein

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110564

N/A

0.165DataRank · unranked

2 citations

Prachi Dabhade, Charlotte Wijne, William McKibben, Simeon D. Draganov, Hedib Alkoumi H Alrawili +10 more

Nanobodies as non-invasive imaging tools

Immuno-Oncology Technology(2020)10.1016/j.iotech.2020.07.001

N/A

0DataRank · unranked

53 citations

Hidde L. Ploegh, Mohammad Rashidian

Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH

Open Biology(2020)10.1098/rsob.190235

N/A

0DataRank · unranked

14 citations

Patrick T. Bruck, M. Aladdin Bhuiyan, Amelia Mitchell-Gears, Michael J. Walsh, Kevin Zhangxu +8 more

A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure

Nature Communications(2020)10.1038/s41467-020-19884-6

N/A

0DataRank · unranked

33 citations

Kasper R. Andersen, Kevin E. Knockenhauer, Jessica R. Ingram, Hidde L. Ploegh, Thomas Schwartz +1 more

Antigen discovery tools for adaptive immune receptor repertoire research

Current Opinion in Systems Biology(2020)10.1016/j.coisb.2020.10.002

N/A

0DataRank · unranked

4 citations

Hidde L. Ploegh, Djenet Bousbaine

Antigen-specific induction of CD4 + CD8αα + intraepithelial T lymphocytes by Bacteroidetes species

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.05.236513

N/A

0DataRank · unranked

4 citations

Preksha Bhagchandani, Mariya London, Mark Mimee, Scott W. Olesen, Mathilde Poyet +11 more

A nanobody suite for yeast scaffold nucleoporins provides details of the Nuclear Pore Complex structure

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.19.161075

N/A

0DataRank · unranked

3 citations

Kasper R. Andersen, Kevin E. Knockenhauer, Jessica R. Ingram, Hidde L. Ploegh, Thomas Schwartz +1 more

Invariant Chain Controls the Activity of Extracellular Cathepsin L

UNC Libraries(2020)10.17615/8wma-nf48

N/A

0DataRank · unranked

0 citations

Ann H. Erickson, Jóse A. Villadangos, Elizabeth K. Bikoff, Ekkehard Weber, Hidde L. Ploegh +3 more

Nanobodies as in vivo , non-invasive, imaging agents

RSC Chemical Biology(2021)10.1039/d1cb00023c

N/A

0DataRank · unranked

74 citations

Ashraful Islam, Novalia Pishesha, Hidde L. Ploegh, Thibault J. Harmand

HIV-infected macrophages resist efficient NK cell-mediated killing while preserving inflammatory cytokine responses

Cell Host & Microbe(2021)10.1016/j.chom.2021.01.006

N/A

0DataRank · unranked

56 citations

Geetha Mylvaganam, Alonso Villasmil-Ocando, Heather Stuart, Marcela V. Maus, Mohammad Rashidian +3 more

A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2116147118

N/A

0DataRank · unranked

35 citations

Thibault J. Harmand, Paul W. Rothlauf, Patrique Praest, Ryan Alexander, Renate van den Doel +16 more

Deletion of mFICD AMPylase alters cytokine secretion and affects visual short-term learning in vivo

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100991

N/A

0DataRank · unranked

22 citations

Corey M. Porter, Anouk M.D. Becker, Chih-Hang Anthony Tang, Charlotte Wijne, Bhaskar K. Chatterjee +6 more

Converting an Anti-Mouse CD4 Monoclonal Antibody into an scFv Positron Emission Tomography Imaging Agent for Longitudinal Monitoring of CD4+ T Cells

The Journal of Immunology(2021)10.4049/jimmunol.2100274

N/A

0DataRank · unranked

16 citations

Novalia Pishesha, Thibault J. Harmand, Hailey M. Heston, Andrew W. Woodham, Ross W. Cheloha +4 more

Activation of a G protein-coupled receptor through indirect antibody-mediated tethering of ligands

RSC Chemical Biology(2021)10.1039/d1cb00118c

N/A

0DataRank · unranked

20 citations

Fabian A. Fischer, Thomas J. Gardella, Hidde L. Ploegh, Ross W. Cheloha

Noninvasive Immuno-PET Imaging of CD8+ T Cell Behavior in Influenza A Virus-Infected Mice

Frontiers in Immunology(2021)10.3389/fimmu.2021.777739

N/A

0DataRank · unranked

14 citations

Zeyang Li, Novalia Pishesha, Yushu Joy Xie, Andrew W. Woodham, Djenet Bousbaine +4 more

Deletion of the AMPylase mFICD alters cytokine secretion and affects cognitive plasticity in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.16.440208

N/A

0DataRank · unranked

1 citations

Corey M. Porter, Anouk M.D. Becker, Chih-Hang Antony Tang, Charlotte Wijne, Bhaskar K. Chatterjee +6 more

Protein visualization and manipulation in Drosophila through the use of epitope tags recognized by nanobodies

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.16.440240

N/A

0DataRank · unranked

1 citations

Ah‐Ram Kim, Ross W. Cheloha, Fabian A. Fischer, Joshua Shing Shun Li, Yuan Feng +7 more

Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance

Research Square(2021)10.21203/rs.3.rs-192181/v1

N/A

0DataRank · unranked

0 citations

Thibault J. Harmand, Liyan Y. Smeding, Weiyi Ma, Leif S. Ludwig, Robine Janssen +8 more

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity

Cell(2022)10.1016/j.cell.2022.01.009

N/A

0DataRank · unranked

124 citations

Valentina Poli, Ellen Shrock, Roberto Spreafico, Xin Liu, Novalia Pishesha +29 more

Humanized antibody potently neutralizes all SARS-CoV-2 variants by a novel mechanism

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.26.497634

N/A

0DataRank · unranked

3 citations

Jun Zhang, Alex J.B. Kreutzberger, Amanda Eaton, Robert J. Edwards, Changbin Jing +25 more

Engineered E. coli for the targeted deposition of therapeutic payloads to sites of disease

Research Square(2022)10.21203/rs.3.rs-1233122/v1

N/A

0DataRank · unranked

2 citations

Coral González-Prieto, Analise Z. Reeves, Urmila Powale, Neha Godbole, Jacqueline M. Tremblay +8 more

Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut

Cell Host & Microbe(2023)10.1016/j.chom.2023.03.007

N/A

0DataRank · unranked

131 citations

Coral González-Prieto, Analise Z. Reeves, Sena Bae, Urmila Powale, Neha Godbole +10 more

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2315163120

N/A

0DataRank · unranked

30 citations

Adán Pinto-Fernández, Dennis Flierman, Jimmy J.L.L. Akkermans, Darragh P. O’Brien, Helene Greenwood +11 more

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

eLife(2023)10.7554/elife.91930

N/A

0DataRank · unranked

18 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka +11 more

An armed anti-immunoglobulin light chain nanobody protects mice against influenza A and B infections

Science Immunology(2023)10.1126/sciimmunol.adg9459

N/A

0DataRank · unranked

24 citations

Thomas Balligand, Claire Carpenet, Hidde L. Ploegh, Xin Liu

Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

JCI Insight(2023)10.1172/jci.insight.158089

N/A

0DataRank · unranked

8 citations

Francesca A. Ververs, Angela Markovska, B. Christoffer Lagerholm, Jordan M Kraaijenhof, Laura I. Yousif +20 more

Multiplexed volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.20.540091

N/A

0DataRank · unranked

5 citations

Xiaotang Lu, Peter H. Li, Shuohong Wang, Richard Schalek, Yaron Meirovitch +14 more

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.16.553641

N/A

0DataRank · unranked

1 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka +11 more

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

eLife(2023)10.7554/elife.91930.1

N/A

0DataRank · unranked

1 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka +10 more

Multiplexed volumetric CLEM enabled by antibody derivatives provides new insights into the cytology of the mouse cerebellar cortex

Research Square(2023)10.21203/rs.3.rs-3121892/v1

N/A

0DataRank · unranked

0 citations

Xiaomeng Han, Xiaotang Lu, Peter H. Li, Shuohong Wang, Richard Schalek +14 more

Reviewer #1 (Public Review): ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

(2023)10.7554/elife.91930.1.sa2

N/A

0DataRank · unranked

0 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu Gurmessa, Ilaria R Merutka +10 more

ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages

eLife(2024)10.7554/elife.91930.3

N/A

0DataRank · unranked

14 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka +11 more

MICA-specific nanobodies for diagnosis and immunotherapy of MICA+ tumors

Frontiers in Immunology(2024)10.3389/fimmu.2024.1368586

N/A

0DataRank · unranked

13 citations

Anouk Knoflook, Novalia Pishesha, Xin Liu, Willemijn J. C. van Keizerswaard, Kai W. Wucherpfennig +2 more

Bi-specific antibody engagers for cancer immunotherapy

Research Square(2024)10.21203/rs.3.rs-4792057/v1

N/A

0DataRank · unranked

1 citations

Camille M. Le Gall, Ryan Alexander, Ella Borgman, Thomas Balligand, Hidde L. Ploegh +1 more

Reviewer #3 (Public Review): ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

(2024)10.7554/elife.91930.2.sa0

N/A

0DataRank · unranked

0 citations

Mila Trank-Greene, Xammy Nguyenla, Aidan Anastas, Sintayehu K Gurmessa, Ilaria R Merutka +11 more

Nanobodies targeting EGFR provide insight into conformations stabilized by glioblastoma mutations

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110374

N/A

0DataRank · unranked

7 citations

Edward P. Harvey, Novalia Pishesha, Hidde L. Ploegh, Timothy A. Springer, Sean Watson

A multivalent nanobody–drug conjugate to prevent and treat influenza virus infections

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2409565122

N/A

0DataRank · unranked

4 citations

Laura Pietrok, Helen E. Rich, Rhogerry Deshycka, Laney Flanagan, Aaron Accardo +3 more

A monoclonal anti-hemagglutinin stem antibody modified with zanamivir protects against both influenza A and B viruses

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2424889122

N/A

0DataRank · unranked

3 citations

Thomas Balligand, Camille M. Le Gall, Hidde L. Ploegh, Xin Liu

A nanobody that binds to the backside of the ubiquitin conjugating enzyme Ube2G2 differentially affects interactions with its partner E3 Ligases

Communications Biology(2025)10.1038/s42003-025-08038-3

N/A

0DataRank · unranked

1 citations

Charlotte Wijne, Zhenyu Sun, Nanette Becht, Ishani Sahay, Novalia Pishesha +2 more

Site-specific labeling uncovers differences in levels and distribution of B-cell receptors of different isotypes on primary B cells

The Journal of Immunology(2025)10.1093/jimmun/vkaf062

N/A

0DataRank · unranked

1 citations

Eugene M. Obeng, Zeyang Li, Tao Fang, Ross W. Cheloha, Hidde L. Ploegh +2 more

Growth inhibition of Saccharomyces cerevisiae by SUMO-specific nanobodies

Scientific Reports(2025)10.1038/s41598-025-02380-6

N/A

0DataRank · unranked

2 citations

Sun Zhen-Yu Jim, Ishani Sahay, Allison Y. Tang, Charlotte Wijne, Jin Gan +4 more

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

Cell(2020)10.1016/j.cell.2020.09.059

N/A

0DataRank · unranked

208 citations

Mandy M. T. van Leent, Abraham J. P. Teunissen, Alexandros Marios Sofias, Vera P. Mourits, Lisa Willemsen +40 more

A modular Uba1-nanobody fusion enables selective ubiquitin transfer to tagged E2 enzymes

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110910

N/A

0DataRank · unranked

0 citations

Francesca D’Amico, David A. Pérez Berrocal, Monique P. C. Mulder, Hidde L. Ploegh, Gan Jin +1 more

Nanobodies in cancer

Seminars in Immunology(2020)10.1016/j.smim.2020.101425

N/A

0DataRank · unranked

116 citations

Andrew W. Woodham, Hidde L. Ploegh, Elisha R. Verhaar

Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments

Cancer Immunology Research(2020)10.1158/2326-6066.cir-19-0734

N/A

0DataRank · unranked

98 citations

Michael Dougan, Jessica R. Ingram, Novalia Pishesha, Tao Fang, Noor Momin +2 more

Improved GPCR ligands from nanobody tethering

Nature Communications(2020)10.1038/s41467-020-15884-8

N/A

0DataRank · unranked

68 citations

Fabian A. Fischer, Andrew W. Woodham, Eileen J. Daley, Naomi Suminski, Thomas J. Gardella +2 more

Hidde L. Ploegh

Indexed papers

Top data-sharing exemplar

Papers