Andrew C. Kruse

Also affiliated with Boston VA Research Institute

Biochemistry, Genetics and Molecular BiologyMedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 50 papers. Top paper: “AlphaFold2 structures guide prospective ligand discovery”.

AlphaFold2 structures guide prospective ligand discovery

Science(2024)10.1126/science.adn6354

N/A

3.3DataRank · unranked

151 citations

Nicholas J. Kapolka, Ryan H. Gumpper, Assaf Alon, Liang Wang, Manish K. Jain +16 more

A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking

eLife(2020)10.7554/elife.52337

N/A

2.0DataRank · unranked

66 citations

T.C.M. Seegar, Stephen C. Blacklow, Andrew C. Kruse, Katherine J. Susa

Mapping and engineering the interaction between adiponectin and T-cadherin

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.010970

N/A

1.1DataRank · unranked

26 citations

Sarah C. Erlandson, Dominique J. Burri, Sanduo Zheng, Andrew C. Kruse, Roberta Pascolutti

Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2

Science(2021)10.1126/science.abi4708

N/A

0.812DataRank · unranked

224 citations

Veronica V. Rezelj, Benoit Fischer, Audrey Fischer, Matthew J. O’Meara, Blandine Monel +24 more

Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors

Cell chemical biology(2024)10.1016/j.chembiol.2024.03.004

N/A

0.771DataRank · unranked

26 citations

Daniel T.D. Jones, Jeffrey S. Smith, Meredith A. Skiba, MARIA F. RICH, Maggie M. Burruss +3 more

COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms

Frontiers in Pharmacology(2021)10.3389/fphar.2021.633680

N/A

0.700DataRank · unranked

105 citations

Philip Tisdall, Philip Fremont‐Smith, Yongfeng Liu, Xi‐Ping Huang, Kris M. White +20 more

Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants

Frontiers in Immunology(2022)10.3389/fimmu.2022.995412

N/A

0.442DataRank · unranked

18 citations

Fiachra Humphries, Roxie C. Girardin, Aaron Wallace, Monir Ejemel, Alla Amcheslavsky +17 more

Phospholipidosis is a shared mechanism underlying the in vitro antiviral activity of many repurposed drugs against SARS-CoV-2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.23.436648

N/A

0.292DataRank · unranked

6 citations

Veronica V. Rezelj, Benoit Fischer, Audrey Fischer, Matthew J. O’Meara, Blandine Monel +18 more

Rapid generation of potent antibodies by autonomous hypermutation in yeast

Nature Chemical Biology(2021)10.1038/s41589-021-00832-4

N/A

0DataRank · unranked

134 citations

Conor McMahon, Morgan S. A. Gilman, Jonathan R. Clements, Sarah A. Clark, Kianna M. Nguyen +13 more

Cryo-EM structure of the B cell co-receptor CD19 bound to the tetraspanin CD81

Science(2021)10.1126/science.abd9836

N/A

0DataRank · unranked

78 citations

Shaun Rawson, Andrew C. Kruse, Stephen C. Blacklow, Katherine J. Susa

Crystal structures of the σ 2 receptor template large-library docking for selective chemotypes active in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.29.441652

N/A

0DataRank · unranked

7 citations

Jiankun Lyu, João M. Bráz, Tia A. Tummino, Veronica Craik, Matthew J. O’Meara +11 more

An in silico method to assess antibody fragment polyreactivity

Nature Communications(2022)10.1038/s41467-022-35276-4

N/A

0DataRank · unranked

62 citations

Jung-Eun Shin, Meredith A. Skiba, Genevieve R. Nemeth, Joseph D. Hurley, Alon Wellner +7 more

Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2201141119

N/A

0DataRank · unranked

12 citations

Meredith A. Skiba, Truc Do, Andrew C. Kruse, Suzanne Walker, Julia E. Page

The SpoVA membrane complex is required for dipicolinic acid import during sporulation and export during germination

Genes & Development(2022)10.1101/gad.349488.122

N/A

0DataRank · unranked

42 citations

Rocío del Carmen Barajas‐Ornelas, Jeremy D. Amon, Fernando H. Ramírez‐Guadiana, Assaf Alon, Kelly P. Brock +4 more

Allosteric activation of cell wall synthesis during bacterial growth

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.07.515454

N/A

0DataRank · unranked

5 citations

Elayne M. Fivenson, Morgan S. A. Gilman, Tyler A. Sisley, Suzanne Walker, Thomas G. Bernhardt +3 more

Engineering and characterization of a long half-life relaxin receptor RXFP1 agonist

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.19.488796

N/A

0DataRank · unranked

4 citations

Jialu Wang, Haoran Jiang, Howard A. Rockman, Andrew C. Kruse, Sarah C. Erlandson

The relaxin receptor RXFP1 signals through a mechanism of autoinhibition

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.22.477343

N/A

0DataRank · unranked

3 citations

Shaun Rawson, James Osei‐Owusu, Kelly P. Brock, Xinyue Liu, Joao A. Paulo +6 more

An in silico method to assess antibody fragment polyreactivity

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.12.476085

N/A

0DataRank · unranked

2 citations

Jung-Eun Shin, Meredith A. Skiba, Genevieve R. Nemeth, Joseph D. Hurley, Alon Wellner +7 more

Metal cofactor stabilization by a partner protein is a widespread strategy employed for amidase activation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.21.477235

N/A

0DataRank · unranked

0 citations

Meredith A. Skiba, Truc Do, Andrew C. Kruse, Suzanne Walker, Julia E. Page

Bacterial spore germination receptors are nutrient-gated ion channels

Science(2023)10.1126/science.adg9829

N/A

0DataRank · unranked

93 citations

Jeremy D. Amon, Lior Artzi, Fernando H. Ramírez‐Guadiana, Kelly P. Brock, Joshua C. Cofsky +4 more

Tetraspanins: structure, dynamics, and principles of partner-protein recognition

Trends in Cell Biology(2023)10.1016/j.tcb.2023.09.003

N/A

0DataRank · unranked

79 citations

Andrew C. Kruse, Stephen C. Blacklow, Katherine J. Susa

Allosteric activation of cell wall synthesis during bacterial growth

Nature Communications(2023)10.1038/s41467-023-39037-9

N/A

0DataRank · unranked

45 citations

Elayne M. Fivenson, Morgan S. A. Gilman, Tyler A. Sisley, Suzanne Walker, Thomas G. Bernhardt +3 more

The relaxin receptor RXFP1 signals through a mechanism of autoinhibition

Nature Chemical Biology(2023)10.1038/s41589-023-01321-6

N/A

0DataRank · unranked

28 citations

Shaun Rawson, James Osei‐Owusu, Kelly P. Brock, Xinyue Liu, Joao A. Paulo +6 more

AlphaFold2 structures template ligand discovery

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.20.572662

N/A

0DataRank · unranked

19 citations

Nicholas J. Kapolka, Ryan H. Gumpper, Assaf Alon, Liang Wang, Manish K. Jain +15 more

Antibodies Expand the Scope of Angiotensin Receptor Pharmacology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.23.554128

N/A

0DataRank · unranked

4 citations

Sarah M. Sterling, Shaun Rawson, Morgan S. A. Gilman, Huixin Xu, Genevieve R. Nemeth +9 more

A Spatiotemporal Map of Co-Receptor Signaling Networks Underlying B Cell Activation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.17.533227

N/A

0DataRank · unranked

2 citations

Gary A. Bradshaw, Robyn J. Eisert, Charlotte M. Schilling, Marian Kalocsay, Stephen C. Blacklow +2 more

A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Nature(2024)10.1038/s41586-023-06799-7

N/A

0DataRank · unranked

154 citations

Morgan S. A. Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek +8 more

Antibodies expand the scope of angiotensin receptor pharmacology

Nature Chemical Biology(2024)10.1038/s41589-024-01620-6

N/A

0DataRank · unranked

37 citations

Sarah M. Sterling, Shaun Rawson, Shuhao Zhang, Huixin Xu, Haoran Jiang +13 more

The M3 Muscarinic Acetylcholine Receptor Can Signal through Multiple G Protein Families

Molecular Pharmacology(2024)10.1124/molpharm.123.000818

N/A

0DataRank · unranked

15 citations

Ari S. Hilibrand, Meredith A. Skiba, Andrew N. Dates, Victor G Calvillo-Miranda, Andrew C. Kruse +1 more

A spatiotemporal map of co-receptor signaling networks underlying B cell activation

Cell Reports(2024)10.1016/j.celrep.2024.114332

N/A

0DataRank · unranked

19 citations

Gary A. Bradshaw, Robyn J. Eisert, Charlotte M. Schilling, Marian Kalocsay, Stephen C. Blacklow +2 more

Engineering and Characterization of a Long-Half-Life Relaxin Receptor RXFP1 Agonist

Molecular Pharmaceutics(2024)10.1021/acs.molpharmaceut.4c00368

N/A

0DataRank · unranked

9 citations

Jialu Wang, Haoran Jiang, James Osei‐Owusu, Howard A. Rockman, Andrew C. Kruse +1 more

SpoVAF and FigP assemble into oligomeric ion channels that enhance spore germination

Genes & Development(2024)10.1101/gad.351353.123

N/A

0DataRank · unranked

16 citations

Jeremy D. Amon, Anna P. Brogan, Lior Artzi, Fernando H. Ramírez‐Guadiana, Joshua C. Cofsky +3 more

MreC-MreD structure reveals a multifaceted interface that controls MreC conformation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.08.617240

N/A

0DataRank · unranked

4 citations

Irina Shlosman, Daniel D. Samé Guerra, Masy Domecillo, Elayne M. Fivenson, Claire Bourett +5 more

Structures of the σ2 receptor enable docking for bioactive ligand discovery

UNC Libraries(2024)10.17615/r2a5-2908

N/A

0DataRank · unranked

0 citations

Jinhao Lyu, B.K. Shoichet, X.-P Huang, J.J. Irwin, João Braz +11 more

The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.13.628440

N/A

0DataRank · unranked

0 citations

Andrea Vettiger, Thomas G. Bernhardt, Andrew C. Kruse, Joseph J. Loparo, Irina Shlosman

Epitope-directed selection of GPCR nanobody ligands with evolvable function

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2423931122

N/A

0DataRank · unranked

14 citations

Clare Canavan, Genevieve R. Nemeth, Jinghan Liu, Ali Kanso, Andrew C. Kruse +1 more

The hit-and-run of cell wall synthesis: LpoB transiently binds and activates PBP1b through a conserved allosteric switch

Nature Communications(2025)10.1038/s41467-025-62051-y

N/A

0DataRank · unranked

5 citations

Andrea Vettiger, Thomas G. Bernhardt, Andrew C. Kruse, Joseph J. Loparo, Irina Shlosman

Conformational regulation of two essential activators of bacterial cell elongation

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2514198122

N/A

0DataRank · unranked

2 citations

Irina Shlosman, Daniel D. Samé Guerra, Masy Domecillo, Elayne M. Fivenson, Claire Bourett +5 more

GPCR Antagonism via Antibody-Mediated Rewiring of Receptor Trafficking and Degradation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.08.669350

N/A

0DataRank · unranked

2 citations

Lawrence Shue, Akimasa Adachi, James Osei‐Owusu, Dingjingyu Zhou, Aoxing Cheng +8 more

G Protein Selectivity in Dopamine Receptors is Determined before GDP Release

Biochemistry(2025)10.1021/acs.biochem.4c00779

N/A

0DataRank · unranked

0 citations

Ari S. Hilibrand, Jeffrey S. Smith, Jennifer Portillo, Andrew C. Kruse, Ravinder Abrol +1 more

Decoding protein-peptide interactions using a large, target-agnostic yeast surface display library

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.19.654863

N/A

0DataRank · unranked

0 citations

Irina Shlosman, Megha Lakshminarayan, Ziyuan Zhao, Yue Hong, Radosław P. Nowak +3 more

Structural coordination of polymerization and crosslinking by a SEDS–bPBP peptidoglycan synthase complex

Nature Microbiology(2020)10.1038/s41564-020-0687-z

N/A

0DataRank · unranked

143 citations

Patricia D. A. Rohs, Morgan S. A. Gilman, Sarah C. Erlandson, Sanduo Zheng, Anna G. Green +9 more

Development of Mutant M3 Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins

Biochemistry(2025)10.1021/acs.biochem.5c00036

N/A

0DataRank · unranked

0 citations

Lizzy Wanka, Nicole A. Perry, Liu Liu, T.M. Iverson, Vsevolod V. Gurevich +4 more

Angiotensin and biased analogs induce structurally distinct active conformations within a GPCR

Science(2020)10.1126/science.aay9813

N/A

0DataRank · unranked

248 citations

Meredith A. Skiba, Conor McMahon, Dean P. Staus, A.L.W. Kleinhenz, Carl‐Mikael Suomivuori +5 more

Molecular mechanism of biased signaling in a prototypical G protein–coupled receptor

Science(2020)10.1126/science.aaz0326

N/A

0DataRank · unranked

244 citations

Naomi R. Latorraca, Laura M. Wingler, Stephan Eismann, Matthew C. King, A.L.W. Kleinhenz +6 more

Synthetic nanobodies as angiotensin receptor blockers

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2009029117

N/A

0DataRank · unranked

63 citations

Dean P. Staus, Laura M. Wingler, Jialu Wang, Meredith A. Skiba, Matthias Elgeti +5 more

Autoantibodies as Endogenous Modulators of GPCR Signaling

Trends in Pharmacological Sciences(2020)10.1016/j.tips.2020.11.013

N/A

0DataRank · unranked

60 citations

Andrew C. Kruse, Meredith A. Skiba

Rapid generation of potent antibodies by autonomous hypermutation in yeast

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.11.378778

N/A

0DataRank · unranked

26 citations

Conor McMahon, Morgan S. A. Gilman, Jonathan R. Clements, Sarah A. Clark, Kianna M. Nguyen +12 more

Protein design and variant prediction using autoregressive generative models

Nature Communications(2021)10.1038/s41467-021-22732-w

N/A

0DataRank · unranked

354 citations

Adam J. Riesselman, Aaron W. Kollasch, Conor McMahon, Elana P. Simon, Chris Sander +4 more

Structures of the σ2 receptor enable docking for bioactive ligand discovery

Nature(2021)10.1038/s41586-021-04175-x

N/A

0DataRank · unranked

198 citations

Jiankun Lyu, João M. Bráz, Tia A. Tummino, Veronica Craik, Matthew J. O’Meara +11 more