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AlphaFold2 structures guide prospective ligand discovery

Science(2024)10.1126/science.adn6354Source: DataRank Database

AlphaFold2 structures guide prospective ligand discovery is a research paper published in Science (2024). On theSindex it has a DataRank of 0. It has been cited 145 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access145 citations

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Linked data & code

uniprot pdb doi

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 24.64)OA: greenTopics (30)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (21)

Nicholas J. Kapolka ORCID,Ryan H. Gumpper ORCID,Assaf Alon ORCID,Liang Wang ORCID,Manish K. Jain ORCID

Live enrichment

PubMed:38753765 PMC:PMC11253030 OpenAlex:https://openalex.org/W4396948746

NIDA NIH HHS

Grant: R01 DA055656

NIGMS NIH HHS

Grant: R01 GM119185

NIMH NIH HHS

Grant: R01 MH112205

NIGMS NIH HHS

Grant: R35 GM122481

NIGMS NIH HHS

Grant: R01 GM133836

NIDA NIH HHS

Grant: R37 DA045657

FWCI

24.64

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

greenLicense: https://www.science.org/content/page/science-licenses-journal-article-reuse

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11253030/pdf/nihms-2007189.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/science.adn6354

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11253030

journalhttps://doi.org/10.1126/science.adn6354

Fields of Study

Pharmacological Receptor Mechanisms and EffectsComputational Drug Discovery MethodsChemical Synthesis and Analysis

MeSH Terms

Deep LearningHumansLigandsProtein ConformationDrug DesignReceptors, sigmaProtein FoldingCryoelectron MicroscopyReceptor, Serotonin, 5-HT2ASmall Molecule LibrariesDrug DiscoverySerotonin 5-HT2 Receptor AgonistsSerotonin 5-HT2 Receptor AntagonistsMolecular Docking Simulation

Keywords

Docking (animal)Computational biologyAffinitiesChemistryStereochemistryLigand (biochemistry)Amino acid residueReceptorBiophysicsBiologyBiochemistryPeptide sequenceMedicine

Sustainable Development Goals

SDG 0: Affordable and clean energy