Sean K. Simmons

Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

5.8Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Single-cell transcriptomic profiling of the aging mouse brain

Nature Neuroscience(2019)10.1038/s41593-019-0491-3

Top 4%

5.6DataRank

Top 4%791 citations

Scott L. Lipnick, Brendan T. Innes, Sean K. Simmons, Xian Adiconis, Danielle Dionne +13 more

Papers

Driven by 25 papers — median percentile 67. Top paper: “Single-cell transcriptomic profiling of the aging mouse brain”.

Single-cell transcriptomic profiling of the aging mouse brain

Nature Neuroscience(2019)10.1038/s41593-019-0491-3

Top 4%

5.6DataRank

Top 4%791 citations

Scott L. Lipnick, Brendan T. Innes, Sean K. Simmons, Xian Adiconis, Danielle Dionne +13 more

Comprehensive comparative analysis of 5′-end RNA-sequencing methods

Nature Methods(2018)10.1038/s41592-018-0014-2

N/A

4.3DataRank · unranked

141 citations

Adam L. Haber, Sean K. Simmons, Pradeep Natarajan, Zhe Ji, Michele A. Busby +8 more

Distinct subnetworks of the thalamic reticular nucleus

Nature(2020)10.1038/s41586-020-2504-5

N/A

4.1DataRank · unranked

217 citations

Violeta G. López-Huerta, Xian Adiconis, Kirsten Levandowski, Soonwook Choi, Sean K. Simmons +25 more

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

Genome Research(2018)10.1101/gr.240390.118

N/A

2.3DataRank · unranked

78 citations

Jenny Chen, Rachel E. Gate, Meena Subramaniam, Tushar Bhangale, Mark N. Lee +18 more

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

Nature(2019)10.1038/s41586-019-1289-x

N/A

1.1DataRank · unranked

1105 citations

Amanda J. Kedaigle, Sean K. Simmons, Allison Nash, Marina Rocha, Giorgia Quadrato +8 more

Autism genes converge on asynchronous development of shared neuron classes

Nature(2022)10.1038/s41586-021-04358-6

N/A

0.918DataRank · unranked

454 citations

Silvia Velasco, Amanda J. Kedaigle, Martina Pigoni, Giorgia Quadrato, Anthony J. Deo +23 more

Author Correction: Systematic comparison of single-cell and single-nucleus RNA-sequencing methods

Nature Biotechnology(2020)10.1038/s41587-020-0534-z

N/A

0.875DataRank · unranked

16 citations

Xian Adiconis, Sean K. Simmons, Monika S. Kowalczyk, Cynthia C. Hession, Nemanja Despot Marjanovic +17 more

In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes

Science(2020)10.1126/science.aaz6063

N/A

0.865DataRank · unranked

319 citations

Sean K. Simmons, Amy Guo, Ashwin S. Shetty, Michelle Ko, Vahbiz Jokhi +12 more

Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.10.376509

N/A

0.840DataRank · unranked

20 citations

Silvia Velasco, Amanda J. Kedaigle, Martina Pigoni, Giorgia Quadrato, Xian Adiconis +16 more

Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

Nature Aging(2023)10.1038/s43587-023-00373-6

N/A

0.641DataRank · unranked

71 citations

Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago +15 more

Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development

Cell(2024)10.1016/j.cell.2024.04.050

N/A

0.639DataRank · unranked

70 citations

Boli Wu, Yuejia Liu, Sean K. Simmons, Kwanho Kim, Grace S. Clarke +19 more

Mostly natural sequencing-by-synthesis for scRNA-seq using Ultima sequencing

Nature Biotechnology(2022)10.1038/s41587-022-01452-6

N/A

0.598DataRank · unranked

53 citations

Gila Lithwick‐Yanai, Xian Adiconis, Florian C. Oberstrass, Nika Iremadze, Kathryn Geiger-Schuller +9 more

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity

Genome biology(2021)10.1186/s13059-021-02301-6

N/A

0.434DataRank · unranked

17 citations

Walaa Oweis, Malka Nissim‐Rafinia, Moria Maman, Shahar Simon, Cynthia C. Hession +13 more

Single cell RNA-seq by mostly-natural sequencing by synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.29.493705

N/A

0.399DataRank · unranked

1 citations

Gila Lithwick-Yanai, Xian Adiconis, Florian Oberstrass, Nika Iremadze, Kathryn Geiger-Schuller +11 more

Heterochronic parabiosis reprograms the mouse brain transcriptome by shifting aging signatures in multiple cell types

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.27.477911

N/A

0.381DataRank · unranked

6 citations

Kristina M. Holton, Richard M. Giadone, Ceren Ozek, Monika Saxena, Samara Santiago +14 more

Author Correction: Comprehensive comparative analysis of 5′-end RNA-sequencing methods

Nature Methods(2018)10.1038/s41592-018-0237-2

N/A

0.352DataRank · unranked

5 citations

Adam L. Haber, Sean K. Simmons, Pradeep Natarajan, Zhe Ji, Michele A. Busby +8 more

Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection

bioRxiv (Cold Spring Harbor Laboratory)(2017)10.1101/188961

N/A

0.305DataRank · unranked

3 citations

Jenny Chen, Rachel E. Gate, Meena Subramaniam, Tushar Bhangale, Mark N. Lee +18 more

Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus

Translational Psychiatry(2025)10.1038/s41398-025-03563-5

Top 63%

0.218DataRank

Top 63%3 citations

Sean K. Simmons, Ajay Nadig, Zohreh Farsi, Wei-Chao Huang, Sameer Aryal +10 more

Systematic evaluation of single-cell multimodal data integration enhances cell type resolution and discovery of clinically relevant states in complex tissues

Genome Biology(2026)10.1186/s13059-026-04002-4

N/A

0.208DataRank · unranked

3 citations

Xian Adiconis, Jessica-Kanglin Li, Domenica Marchese, Ginevra Caratù, Chung-Chau Hon +22 more

Lupus autoantibodies initiate a maladaptive equilibrium sustained by HMGB1:RAGE signaling and reversed by LAIR-1:C1q signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.01.538935

N/A

0DataRank · unranked

1 citations

Mark Mizrachi, Sean K. Simmons, Bahtiyar Toz, Jeffrey Wingard, Nazila Tehrani +7 more

A single-cell map of antisense oligonucleotide activity in the brain

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.14.528473

N/A

0DataRank · unranked

5 citations

Juliana E Gentile, Naeem Nadaf, Charles R. Vanderburg, Sean K. Simmons, Dan Dubinsky +9 more

Lupus autoantibodies initiate neuroinflammation sustained by continuous HMGB1:RAGE signaling and reversed by increased LAIR-1 expression

Nature Immunology(2024)10.1038/s41590-024-01772-6

N/A

0DataRank · unranked

35 citations

Mark Mizrachi, Sean K. Simmons, Bahtiyar Toz, Czeslawa Kowal, Jeffrey Wingard +9 more

A single-cell map of antisense oligonucleotide activity in the brain

Nucleic Acids Research(2023)10.1093/nar/gkad371

N/A

0DataRank · unranked

52 citations

Juliana E Gentile, Naeem Nadaf, Charles R. Vanderburg, Sean K. Simmons, Dan Dubinsky +9 more

Methods to generate single-nucleus RNA-seq libraries from lung cancer samples v1

(2025)10.17504/protocols.io.36wgqpk9yvk5/v1

N/A

0DataRank · unranked

0 citations

Sean K. Simmons, Nathan Haywood, Xian Adiconis, Joshua Z. Levin, Jixiang Zhang

Privacy-Preserving Biomedical Database Queries with Optimal Privacy-Utility Trade-Offs

Cell Systems(2020)10.1016/j.cels.2020.03.006

N/A

0DataRank · unranked

27 citations

Sean K. Simmons, Ryan Kim, Bonnie Berger, Hyunghoon Cho

Sean K. Simmons

Indexed papers

Top data-sharing exemplar

Papers