Raúl Urrutia

Centre National de la Recherche Scientifique

Also affiliated with Inserm, Medical College of Wisconsin, Mayo Clinic in Arizona, Mayo Clinic Hospital, Centre de Recherche en Cancérologie de Marseille

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 54 papers. Top paper: “Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature”.

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature

eLife(2020)10.7554/elife.51339

N/A

1.1DataRank · unranked

26 citations

Jason Siebert, Robert Burns, Yongwei Zheng, Ao Mei, Benedetta Bonacci +8 more

Role of cGAS/STING pathway in aging and sexual dimorphism in diabetic kidney disease

JCI Insight(2024)10.1172/jci.insight.174126

N/A

0.563DataRank · unranked

16 citations

Lashodya V. Dissanayake, Ammar J. Alsheikh, Adrian Zietara, Denisha Spires, Romica Kerketta +5 more

Targeting the CBP/β-Catenin Interaction to Suppress Activation of Cancer-Promoting Pancreatic Stellate Cells

Cancers(2020)10.3390/cancers12061476

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0DataRank · unranked

17 citations

Soo-Mi Kweon, Jia-Ling Teo, Yate‐Ching Yuan, Laleh G. Melstrom, Richard T. Waldron +5 more

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations

Bioinformatics(2020)10.1093/bioinformatics/btaa972

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0DataRank · unranked

12 citations

Nikita R. Dsouza, Raúl Urrutia, Michael T. Zimmermann, Swarnendu Tripathi

Discovery, expression, cellular localization, and molecular properties of a novel, alternative spliced HP1γ isoform, lacking the chromoshadow domain

PLoS ONE(2020)10.1371/journal.pone.0217452

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0DataRank · unranked

7 citations

Thiago M. de Assuncao, Nikita R. Dsouza, Monique Williams, Michael T. Zimmermann, Raúl Urrutia +2 more

A GATA6-centered gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.09.033456

N/A

0DataRank · unranked

5 citations

Natascha Hruschka, Vivien Ionasz, Rupert Oellinger, Sebastian Mueller, Jaime Martínez de Villarreal +12 more

Impact of CDKN2A/b status in pancreatic cancer (PC).

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.4_suppl.759

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0DataRank · unranked

0 citations

Claire Griffiths, Igli Arapi, Matthew Lasowski, Arun K. Singavi, Kulwinder S. Dua +13 more

A GATA6-centred gene regulatory network involving HNFs and ΔNp63 controls plasticity and immune escape in pancreatic cancer

Gut(2021)10.1136/gutjnl-2020-321397

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0DataRank · unranked

87 citations

Vivien Ionasz, Sumit Paliwal, Natascha Hruschka, Jaime Martínez de Villarreal, Rupert Öllinger +14 more

SASH3variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

Blood(2021)10.1182/blood.2020008629

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0DataRank · unranked

56 citations

Jenna Bergerson, Tomoki Kawai, Hye Sun Kuehn, David H. McDermott, Irene Cortese +30 more

BMI1 maintains the Treg epigenomic landscape to prevent inflammatory bowel disease

Journal of Clinical Investigation(2021)10.1172/jci140755

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0DataRank · unranked

26 citations

Adebowale O. Bamidele, Phyllis A. Svingen, Mary R. Sagstetter, Thomas C. Smyrk, Joseph M. Gaballa +14 more

KrasG12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells

Genome biology(2021)10.1186/s13059-021-02498-6

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0DataRank · unranked

16 citations

Romica Kerketta, Thiago M. de Assuncao, Elise Leverence, Atefeh Zeighami, Guillermo Urrutia +7 more

Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics

Computational and Structural Biotechnology Journal(2021)10.1016/j.csbj.2021.12.007

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0DataRank · unranked

10 citations

Nikita R. Dsouza, Angela Mathison, Elise Leverence, Raúl Urrutia, Michael T. Zimmermann +1 more

Inactivation of the Euchromatic Histone-Lysine N-Methyltransferase 2 Pathway in Pancreatic Epithelial Cells Antagonizes Cancer Initiation and Pancreatitis-Associated Promotion by Altering Growth and Immune Gene Expression Networks

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.681153

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0DataRank · unranked

10 citations

Thiago M. de Assuncao, Angela Mathison, Ann Salmonson, Romica Kerketta, Atefeh Zeighami +9 more

Effects of Subnormothermic Regulated Hepatic Reperfusion on Mitochondrial and Transcriptomic Profiles in a Porcine Model

Annals of Surgery(2021)10.1097/sla.0000000000005156

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0DataRank · unranked

10 citations

Michael A. Zimmerman, Woo Young Shin, Brent T. Boettcher, Ju‐Seog Lee, Jong‐In Park +13 more

Computational modeling reveals key molecular properties and dynamic behavior of disruptor of telomeric silencing 1‐like ( DOT1L ) and partnering complexes involved in leukemogenesis

Proteins Structure Function and Bioinformatics(2021)10.1002/prot.26219

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0DataRank · unranked

5 citations

Young‐In Chi, Thiago M. de Assuncao, Elise Leverence, Swarnendu Tripathi, Nikita R. Dsouza +7 more

“Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes

Molecular Cell(2022)10.1016/j.molcel.2022.06.029

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0DataRank · unranked

73 citations

Supriya V. Vartak, A. Conte, Xiang Wang, David A. Garcia, Evan Stevens +20 more

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

Computational and Structural Biotechnology Journal(2022)10.1016/j.csbj.2022.04.028

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0DataRank · unranked

12 citations

Timothy J. Stodola, Thiago M. de Assuncao, Elise Leverence, Brian C. Smith, Brian F. Volkman +5 more

Integrative Modeling, Molecular Mechanics, and Molecular Dynamics Evaluation of Genomics Variants in KMT2C (MLL3), a Gene Involved in Kleefstra Syndrome Type 2

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5710

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0DataRank · unranked

1 citations

Young‐In Chi, Thiago M. de Assuncao, Angela Mathison, Brian F. Volkman, Brian D. Smith +4 more

Functional Inferences Derived from Defining the Interactome of H3K9me2 Writers and Readers

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5587

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0DataRank · unranked

0 citations

Thiago M. de Assuncao, Gwen Lomberk, Raúl Urrutia, Gareth Pollin

Defining the Mutational Landscape That Affects the Histone Demethylase KDM6A/UTX in Human Cancer

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5656

N/A

0DataRank · unranked

0 citations

Timothy J. Stodola, Thiago M. de Assuncao, Brian F. Volkman, Brian D. Smith, Angela Mathison +4 more

Epigenomic mechanisms used by KrasG12D to regulate inflammatory gene clusters in epithelial pancreatic cancer cells, which are critical for reprogramming the tumor microenvironment

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5762

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0DataRank · unranked

0 citations

Jenica Abrudan, Guillermo Urrutia, Thiago M. de Assuncao, Angela Mathison, Michael T. Zimmermann +3 more

Rho‐related BTB Domain‐containing Protein 1 Reverses Established Arterial Stiffness in Angiotensin II‐treated Mice

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r4001

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0DataRank · unranked

0 citations

Jing Wu, John J. Reho, Ko‐Ting Lu, Daniel Brozoski, Alec Werthman +11 more

Transcriptional Landscape Established by the Euchromatic Histone‐lysine N‐methyltransferase Pathway During Pancreas Ontogenesis and Pancreatitis

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5543

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0DataRank · unranked

0 citations

Ann Salmonson, Guillermo Urrutia, Thiago M. de Assuncao, Michael T. Zimmermann, Angela Mathison +2 more

To ChIP, or to CUT, that is the question: Comparative Evaluation of NextGen Methodologies for Studying the genome‐wide distribution of Histone H3 Lysine 9 di‐methyl mark in pancreatic cells

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5476

N/A

0DataRank · unranked

0 citations

Jenica Abrudan, Meijun Du, Thiago M. de Assuncao, Angela Mathison, Michael T. Zimmermann +3 more

KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

Research Square(2022)10.21203/rs.3.rs-2003235/v1

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0DataRank · unranked

0 citations

Dharmendra Bhargava, Xiao CHEN, Taicheng Zhou, Gizem Dursuk, Wenpeng Jiang +7 more

The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis

Nature Communications(2023)10.1038/s41467-022-34464-6

N/A

0DataRank · unranked

355 citations

Yongxia Wu, Kun Fang, Sean Sweeney, Ulyss K. Roesner, Melodie Parrish +14 more

KLF5 and p53 comprise an incoherent feed-forward loop directing cell-fate decisions following stress

Cell Death and Disease(2023)10.1038/s41419-023-05731-1

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0DataRank · unranked

10 citations

Dharmendra Bhargava, Xiao CHEN, Taicheng Zhou, Gizem Dursuk, Wenpeng Jiang +7 more

RAG genomic variation causes autoimmune diseases through specific structure-based mechanisms of enzyme dysregulation

iScience(2023)10.1016/j.isci.2023.108040

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0DataRank · unranked

9 citations

Tomoki Kawai, Brian D. Ratnasinghe, Jessica B. Wagenknecht, Raúl Urrutia, Luigi D. Notarangelo +2 more

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.10.003

N/A

0DataRank · unranked

8 citations

Neshatul Haque, Jessica B. Wagenknecht, Davin R. Jensen, Guadalupe Esparza, Elise Leverence +8 more

Deep computational phenotyping of genomic variants impacting the SET domain of KMT2C reveal molecular mechanisms for their dysfunction

Frontiers in Genetics(2023)10.3389/fgene.2023.1291307

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0DataRank · unranked

6 citations

Young‐In Chi, Jose Lizarraga Mazaba, Neshatul Haque, Jessica B. Wagenknecht, Brian C. Smith +6 more

A multi-layered computational structural genomics approach enhances domain-specific interpretation of Kleefstra syndrome variants in EHMT1

Computational and Structural Biotechnology Journal(2023)10.1016/j.csbj.2023.10.022

N/A

0DataRank · unranked

2 citations

Salomão Dória Jorge, Davin R. Jensen, Brian C. Smith, Brian F. Volkman, Angela Mathison +4 more

Writers and readers of H3K9me2 form distinct protein networks during the cell cycle that include candidates for H3K9 mimicry

Bioscience Reports(2023)10.1042/bsr20231093

N/A

0DataRank · unranked

1 citations

Thiago M. de Assuncao, Salomão Dória Jorge, Young‐In Chi, M. Cristine Charlesworth, Benjamin J. Madden +5 more

Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.28.536249

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0DataRank · unranked

2 citations

Neshatul Haque, Jessica B. Wagenknecht, Davin R. Jensen, Guadalupe V. Esparza, Elise Leverence +8 more

Overlapping and Distinct Functions of an Extended Repertoire of KRAS Mutations

Research Square(2023)10.21203/rs.3.rs-2883088/v1

N/A

0DataRank · unranked

0 citations

Angela Mathison, Xuan Li, Elise Leverence, Davin R. Jensen, Guadalupe Esparza +6 more

A Multi-Layered Computational Structural Genomics Approach Enhances Domain-Specific Interpretation of Kleefstra Syndrome Variants in EHMT1

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.06.556558

N/A

0DataRank · unranked

0 citations

Salomão Dória Jorge, Davin R. Jensen, Brian C. Smith, Brian F. Volkman, Angela Mathison +4 more

Identification of novel loci for multiple myeloma when comparing with its precursor condition monoclonal gammopathy of unknown significance

Leukemia(2023)10.1038/s41375-023-02078-6

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0DataRank · unranked

0 citations

Shahram Arsang‐Jang, Ben Massat, Bicky Thapa, Victoria Patek, Anita D’Souza +7 more

Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells

Free Radical Biology and Medicine(2024)10.1016/j.freeradbiomed.2024.01.003

N/A

0DataRank · unranked

22 citations

Adrian Lim, Omer H. Elmadbouh, Mouad Edderkaoui, Arsen Osipov, Angela Mathison +5 more

Targeting the Epigenetic Regulator CBX5 Promotes Fibroblast Metabolic Reprogramming and Inhibits Lung Fibrosis

American Journal of Respiratory Cell and Molecular Biology(2024)10.1165/rcmb.2024-0255oc

N/A

0DataRank · unranked

6 citations

Tho X. Pham, Jisu Lee, Ahmed Raslan, K. Nicolas, Andrey A. Sharov +6 more

Cancer-associated polybromo-1 bromodomain 4 missense variants variably impact bromodomain ligand binding and cell growth suppression

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107146

N/A

0DataRank · unranked

8 citations

Christopher G. Goetz, Guanming Jiao, Raymundo Nuñez, Michael D. Olp, Alisha Dhiman +6 more

Enhancing prognostic power in multiple myeloma using a plasma cell signature derived from single-cell RNA sequencing

Blood Cancer Journal(2024)10.1038/s41408-024-01024-8

N/A

0DataRank · unranked

7 citations

Shahram Arsang‐Jang, Yan Cheng, Fumou Sun, Anita D’Souza, Binod Dhakal +11 more

Ehmt2 inactivation in pancreatic epithelial cells shapes the transcriptional landscape and inflammation response of the whole pancreas

Frontiers in Genetics(2024)10.3389/fgene.2024.1412767

N/A

0DataRank · unranked

3 citations

Angela Mathison, Thiago M. de Assuncao, Anju Thomas, Atefeh Zeighami, Ann Salmonson +11 more

Mutant KRAS inhibitors enter the scene of precision therapeutics for pancreatic cancer

Journal of Gastrointestinal Oncology(2024)10.21037/jgo-24-326

N/A

0DataRank · unranked

2 citations

Gwen Lomberk, Angela Mathison, Michael T. Zimmermann, Raúl Urrutia, Gareth Pollin

Emergent properties of the lysine methylome reveal regulatory roles via protein interactions and histone mimicry

Epigenomics(2024)10.1080/17501911.2024.2435244

N/A

0DataRank · unranked

1 citations

Young‐In Chi, Angela Mathison, Michael T. Zimmermann, Gwen Lomberk, Raúl Urrutia +1 more

Changes in Daily Apparent Diffusion Coefficient on Fully Quantitative Magnetic Resonance Imaging Correlate With Established Genomic Pathways of Radiation Sensitivity and Reveal Novel Biologic Associations

International Journal of Radiation Oncology*Biology*Physics(2024)10.1016/j.ijrobp.2024.03.042

N/A

0DataRank · unranked

1 citations

Angela Mathison, Elias DeVoe, Michael Tschannen, Jaime Wendt-Andrae, Michael Straza +13 more

Abnormal Redox Balance at Membrane Contact Sites Causes Axonopathy in Gdap1-related Charcot-marie-tooth Disease

Research Square(2024)10.21203/rs.3.rs-5682984/v1

N/A

0DataRank · unranked

1 citations

Lara Cantarero, Mónica Roldán, María Rodríguez-Sanz, Angela Mathison, Yaiza Díaz‐Osorio +5 more

EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.14.584700

N/A

0DataRank · unranked

0 citations

Angela Mathison, Thiago M. de Assuncao, Anju Thomas, L. Zeighami, Ann Salmonson +10 more

The triple code model for advancing research in rare and undiagnosed diseases beyond the base pairs

Epigenomics(2024)10.1080/17501911.2024.2436837

N/A

0DataRank · unranked

0 citations

Raúl Urrutia, Gwen Lomberk

An Analytical Approach that Combines Knowledge from Germline and Somatic Mutations Enhances Tumor Genomic Reanalyses in Precision Oncology

Journal of Computational Biology(2024)10.1089/cmb.2023.0461

N/A

0DataRank · unranked

0 citations

Honey V. Reddi, Bradley Taylor, Samantha Stachowiak, Jennifer L. Geurts, Ben George +4 more

Advancing deep variant phenotyping of mitochondrial enzyme complexes for precision medicine in allogeneic hematopoietic stem-cell transplantation

Transplantation Reports(2025)10.1016/j.tpr.2025.100171

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0DataRank · unranked

0 citations

Michael T. Zimmermann, Neshatul Haque, Shahram Arsang‐Jang, Wael Saber, Xiaowu Gai +2 more

An Integrative Multitiered Computational Analysis for Better Understanding the Structure and Function of 85 Miniproteins

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.31.635936

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0DataRank · unranked

0 citations

Gareth Pollin, Jessica B. Wagenknecht, Raúl Urrutia, Michael T. Zimmermann, Reethika Veluri

Genomic features of the methylosome protein MEP50 and its implications in hormone signaling and cancer

Endocrine Connections(2025)10.1530/ec-25-0444

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0DataRank · unranked

0 citations

Young‐In Chi, Raúl Urrutia, Gwen Lomberk, Gareth Pollin

PAX1 is essential for development and function of the human thymus

Science Immunology(2020)10.1126/sciimmunol.aax1036

N/A

0DataRank · unranked

98 citations

Raúl Urrutia, Luis M. Franco, Silvia Giliani, Kejian Zhang, Anas M. Alazami +23 more

An integrative multitiered computational analysis for better understanding the structure and function of 85 miniproteins

NAR Genomics and Bioinformatics(2025)10.1093/nargab/lqaf178

N/A

0DataRank · unranked

0 citations

Gareth Pollin, Jessica B. Wagenknecht, Raúl Urrutia, Michael T. Zimmermann, Reethika Veluri

POLD1 Deficiency Reveals a Role for POLD1 in DNA Repair and T and B Cell Development

Journal of Clinical Immunology(2020)10.1007/s10875-020-00903-6

N/A

0DataRank · unranked

20 citations

Ottavia M. Delmonte, Vanessa Bundy, Marita Bosticardo, Michael T. Zimmermann, Nikita R. Dsouza +12 more