César de la Fuente‐Núñez

ORCID: 0000-0002-2005-5629

Also affiliated with Translational Therapeutics (United States), Penn Center for AIDS Research, University of Pennsylvania, Philadelphia University

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.573Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Challenges in computational discovery of bioactive peptides in ’omics data

PROTEOMICS(2024)10.1002/pmic.202300105

Top 34%

0.573DataRank

Top 34%16 citations

Célio Dias Santos Júnior, César de la Fuente‐Núñez, Luís Pedro Coelho

Papers

Driven by 84 papers — median percentile 66. Top paper: “The value of antimicrobial peptides in the age of resistance”.

The value of antimicrobial peptides in the age of resistance

The Lancet Infectious Diseases(2020)10.1016/s1473-3099(20)30327-3

N/A

1.0DataRank · unranked

1075 citations

Pushpanathan Muthuirulan, Ana L. Santos, Leon G. Leanse, Michael Fernández, Anastasios Ioannidis +14 more

Challenges in computational discovery of bioactive peptides in ’omics data

PROTEOMICS(2024)10.1002/pmic.202300105

Top 34%

0.573DataRank

Top 34%16 citations

Célio Dias Santos Júnior, César de la Fuente‐Núñez, Luís Pedro Coelho

Light-Emitting Probes for Labeling Peptides

Cell Reports Physical Science(2020)10.1016/j.xcrp.2020.100257

N/A

0DataRank · unranked

12 citations

Lucía Ageitos, Marcelo D. T. Torres, Fernando H. Bartoloni, César de la Fuente‐Núñez, Andreia Boaro

Accelerating antibiotic discovery through artificial intelligence

Communications Biology(2021)10.1038/s42003-021-02586-0

N/A

0DataRank · unranked

223 citations

Jacqueline R. M. A. Maasch, César de la Fuente‐Núñez, Marcelo C. R. Melo

Hydrogel-based biocontainment of bacteria for continuous sensing and computation

Nature Chemical Biology(2021)10.1038/s41589-021-00779-6

N/A

0DataRank · unranked

248 citations

Eléonore Tham, Xinyue Liu, Kevin Yehl, Alexis J. Rovner, Hyunwoo Yuk +5 more

Mining for encrypted peptide antibiotics in the human proteome

Nature Biomedical Engineering(2021)10.1038/s41551-021-00801-1

N/A

0DataRank · unranked

193 citations

Marcelo C. R. Melo, Laurice Flowers, Orlando Crescenzi, Eugenio Notomista, César de la Fuente‐Núñez +1 more

Low-cost biosensor for rapid detection of SARS-CoV-2 at the point of care

Matter(2021)10.1016/j.matt.2021.05.003

N/A

0DataRank · unranked

123 citations

William R. de Araújo, Lucas F. de Lima, André L. Ferreira, César de la Fuente‐Núñez, Marcelo D. T. Torres

Low-Cost Optodiagnostic for Minute-Time Scale Detection of SARS-CoV-2

ACS Nano(2021)10.1021/acsnano.1c03236

N/A

0DataRank · unranked

63 citations

Lucas F. de Lima, Marcelo D. T. Torres, William R. de Araújo, César de la Fuente‐Núñez, André L. Ferreira

Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

The Science of The Total Environment(2022)10.1016/j.scitotenv.2022.160461

N/A

0DataRank · unranked

154 citations

Zhenlong Wang, Jianhua Guo, César de la Fuente‐Núñez, Jinquan Wang, Bing Han +4 more

Deep generative models for peptide design

Digital Discovery(2022)10.1039/d1dd00024a

N/A

0DataRank · unranked

129 citations

Daphne Kontogiorgos-Heintz, César de la Fuente‐Núñez, Fang Wan

Synthetic Antibiotic Derived from Sequences Encrypted in a Protein from Human Plasma

ACS Nano(2022)10.1021/acsnano.1c04496

N/A

0DataRank · unranked

50 citations

Marcelo D. T. Torres, Rosa Gaglione, Eliana Dell’Olmo, Rocco Di Girolamo, Andrea Bosso +6 more

Debulking different Corona (SARS-CoV-2 delta, omicron, OC43) and Influenza (H1N1, H3N2) virus strains by plant viral trap proteins in chewing gums to decrease infection and transmission

Biomaterials(2022)10.1016/j.biomaterials.2022.121671

N/A

0DataRank · unranked

33 citations

Smruti K. Nair, Hancheng Guan, Yuwei Guo, Rachel J. Kulchar, Marcelo D. T. Torres +20 more

Impact of natural selection on global patterns of genetic variation and association with clinical phenotypes at genes involved in SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2123000119

N/A

0DataRank · unranked

18 citations

Anurag Verma, Yuanqing Feng, Marcelo C. R. Melo, Michael A. McQuillan, Matthew E.B. Hansen +71 more

An N-capping asparagine–lysine–proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold

Chemical Science(2022)10.1039/d1sc06998e

N/A

0DataRank · unranked

13 citations

Lai Yue Chan, Elizabete de Souza Cândido, Danieli Fernanda Buccini, Samilla B. Rezende, Marcelo D. T. Torres +9 more

Detection of SARS-CoV-2 with RAPID: A prospective cohort study

iScience(2022)10.1016/j.isci.2022.104055

N/A

0DataRank · unranked

9 citations

Lucas F. de Lima, André L. Ferreira, William R. de Araújo, Paul L. Callahan, Antonio Dávila +3 more

Identification of the first COVID-19 infections in the US using a retrospective analysis (REMEDID)

Spatial and Spatio-temporal Epidemiology(2022)10.1016/j.sste.2022.100517

N/A

0DataRank · unranked

5 citations

Enrique Morales, César de la Fuente‐Núñez, Isabel Vigo, Eva S. Fonfría, César Bordehore +1 more

Molecular tools for probing the microbiome

Current Opinion in Structural Biology(2022)10.1016/j.sbi.2022.102415

N/A

0DataRank · unranked

4 citations

César de la Fuente‐Núñez, Marcelo D. T. Torres

Author Correction: Mining for encrypted peptide antibiotics in the human proteome

Nature Biomedical Engineering(2022)10.1038/s41551-022-00967-2

N/A

0DataRank · unranked

14 citations

Marcelo C. R. Melo, Laurice Flowers, Orlando Crescenzi, Eugenio Notomista, César de la Fuente‐Núñez +1 more

Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.15.516443

N/A

0DataRank · unranked

9 citations

Marcelo D. T. Torres, Marcelo C. R. Melo, César de la Fuente‐Núñez, Jacqueline R. M. A. Maasch

Leveraging artificial intelligence in the fight against infectious diseases

Science(2023)10.1126/science.adh1114

N/A

0DataRank · unranked

282 citations

César de la Fuente‐Núñez, James J. Collins, Felix Wong

Antibiotic failure: Beyond antimicrobial resistance

Drug Resistance Updates(2023)10.1016/j.drup.2023.101012

N/A

0DataRank · unranked

234 citations

Angela Cesaro, Robert E. W. Hancock, César de la Fuente‐Núñez

Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning

Cell Host & Microbe(2023)10.1016/j.chom.2023.07.001

N/A

0DataRank · unranked

146 citations

Marcelo D. T. Torres, Marcelo C. R. Melo, César de la Fuente‐Núñez, Jacqueline R. M. A. Maasch

Deep learning tools to accelerate antibiotic discovery

Expert Opinion on Drug Discovery(2023)10.1080/17460441.2023.2250721

N/A

0DataRank · unranked

63 citations

Mojtaba Bagheri, Marcelo D. T. Torres, Fang Wan, César de la Fuente‐Núñez, Angela Cesaro

Advanced delivery systems for peptide antibiotics

Advanced Drug Delivery Reviews(2023)10.1016/j.addr.2023.114733

N/A

0DataRank · unranked

60 citations

Shuang‐Zhe Lin, Norbert Pardi, César de la Fuente‐Núñez, Angela Cesaro

Geometric deep learning as a potential tool for antimicrobial peptide prediction

Frontiers in Bioinformatics(2023)10.3389/fbinf.2023.1216362

N/A

0DataRank · unranked

42 citations

Marlon H. Cardoso, Abel Gil-Ley, Lívia V. Luchi, Maria G. L. da Silva, Maria Lı́gia Rodrigues Macedo +3 more

Structure-function-guided design of synthetic peptides with anti-infective activity derived from wasp venom

Cell Reports Physical Science(2023)10.1016/j.xcrp.2023.101459

N/A

0DataRank · unranked

38 citations

Lucía Ageitos, Marcelo D. T. Torres, Esther Broset Blasco, Sebahat Öztekin, César de la Fuente‐Núñez +1 more

A bacterial cellulose-based and low-cost electrochemical biosensor for ultrasensitive detection of SARS-CoV-2

Cell Reports Physical Science(2023)10.1016/j.xcrp.2023.101476

N/A

0DataRank · unranked

31 citations

André L. Ferreira, Ishani Ranjan, Ronald G. Collman, William R. de Araújo, César de la Fuente‐Núñez +1 more

Molecular hybridization strategy for tuning bioactive peptide function

Communications Biology(2023)10.1038/s42003-023-05254-7

N/A

0DataRank · unranked

20 citations

Marcelo D. T. Torres, Cyntia Silva Oliveira, Adriana F. Silva, Gislaine Patricia Andrade, Yiming Wang +8 more

Stability of Ti3C2Tx MXene Films and Devices under Clinical Sterilization Processes

ACS Nano(2023)10.1021/acsnano.3c01525

N/A

0DataRank · unranked

17 citations

Doris Xu, Brendan B. Murphy, Kateryna Shevchuk, Sneha Shankar, Mark Anayee +6 more

Recombinant production of antimicrobial peptides in plants

Biotechnology Advances(2023)10.1016/j.biotechadv.2023.108296

N/A

0DataRank · unranked

23 citations

Marcelo D. T. Torres, César de la Fuente‐Núñez, Farhad Nazarian‐Firouzabadi

Computational Design of Peptides for Biomaterials Applications

ACS Applied Bio Materials(2023)10.1021/acsabm.2c01023

N/A

0DataRank · unranked

17 citations

Kathleen J. Stebe, César de la Fuente‐Núñez, Ravi Radhakrishnan, Yiming Wang

Rapid and accurate detection of herpes simplex virus type 2 using a low-cost electrochemical biosensor

Cell Reports Physical Science(2023)10.1016/j.xcrp.2023.101513

N/A

0DataRank · unranked

11 citations

André L. Ferreira, Sita Awasthi, Marcelo D. T. Torres, Harvey M. Friedman, Gary H. Cohen +3 more

Computational exploration of the global microbiome for antibiotic discovery

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555663

N/A

0DataRank · unranked

21 citations

Marcelo D. T. Torres, Yiqian Duan, Álvaro Rodríguez del Río, Thomas Schmidt, Hui Chong +12 more

Human gut metagenomic mining reveals an untapped source of peptide antibiotics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.31.555711

N/A

0DataRank · unranked

12 citations

Erin F. Brooks, Angela Cesaro, Hila Sberro, Cosmos Nicolaou, Ami S. Bhatt +2 more

Editorial: Community series in antimicrobial peptides: Molecular design, structure function relationship and biosynthesis optimization

Frontiers in Microbiology(2023)10.3389/fmicb.2023.1125426

N/A

0DataRank · unranked

11 citations

Rustam Aminov, Octávio Luiz Franco, César de la Fuente‐Núñez, Jianhua Wang, Na Yang

Molecular de-extinction of antibiotics enabled by deep learning

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.01.560353

N/A

0DataRank · unranked

8 citations

Marcelo D. T. Torres, Jacqueline Peng, César de la Fuente‐Núñez, Fang Wan

AI in infectious diseases: The role of datasets

Drug Resistance Updates(2024)10.1016/j.drup.2024.101067

N/A

0DataRank · unranked

22 citations

César de la Fuente‐Núñez

Antimicrobial resistance: a concise update

The Lancet Microbe(2024)10.1016/j.lanmic.2024.07.010

N/A

0DataRank · unranked

525 citations

Carlos T H Wong, Thet Tun Aung, Rajamani Lakshminarayanan, Jodhbir S. Mehta, Saaeha Rauz +7 more

Discovery of antimicrobial peptides in the global microbiome with machine learning

Cell(2024)10.1016/j.cell.2024.05.013

N/A

0DataRank · unranked

353 citations

Marcelo D. T. Torres, Yiqian Duan, Álvaro Rodríguez del Río, Thomas Schmidt, Hui Chong +12 more

Machine learning for antimicrobial peptide identification and design

Nature Reviews Bioengineering(2024)10.1038/s44222-024-00152-x

N/A

0DataRank · unranked

229 citations

Felix Wong, James J. Collins, César de la Fuente‐Núñez, Fang Wan

Deep-learning-enabled antibiotic discovery through molecular de-extinction

Nature Biomedical Engineering(2024)10.1038/s41551-024-01201-x

N/A

0DataRank · unranked

163 citations

Marcelo D. T. Torres, Jacqueline Peng, César de la Fuente‐Núñez, Fang Wan

Mining human microbiomes reveals an untapped source of peptide antibiotics

Cell(2024)10.1016/j.cell.2024.07.027

N/A

0DataRank · unranked

147 citations

Erin F. Brooks, Angela Cesaro, Hila Sberro, Matthew O Gill, Cosmos Nicolaou +3 more

Low-Cost Biosensor Technologies for Rapid Detection of COVID-19 and Future Pandemics

ACS Nano(2024)10.1021/acsnano.3c01629

N/A

0DataRank · unranked

94 citations

Heather Lukas, Marcelo D. T. Torres, Wei Gao, César de la Fuente‐Núñez, William R. de Araújo

From Data to Decisions: Leveraging Artificial Intelligence and Machine Learning in Combating Antimicrobial Resistance – a Comprehensive Review

Journal of Medical Systems(2024)10.1007/s10916-024-02089-5

N/A

0DataRank · unranked

71 citations

Samuel J. T. Wardell, Tarun Pal, César de la Fuente‐Núñez, Daniel Pletzer, José Manuel Pérez de la Lastra

Lanthanide binding peptide surfactants at air–aqueous interfaces for interfacial separation of rare earth elements

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2411763121

N/A

0DataRank · unranked

24 citations

Felipe Jiménez‐Ángeles, Jason G. Marmorstein, Yiming Wang, Stephen A. Crane, S. Surabh +20 more

Computational Design of Pore-Forming Peptides with Potent Antimicrobial and Anticancer Activities

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00912

N/A

0DataRank · unranked

21 citations

Marcelo D. T. Torres, Miroslav Boudný, Markéta Koběrská, Floriana Cappiello, Miroslav Popper +11 more

Polyproline peptide targets Klebsiella pneumoniae polysaccharides to collapse biofilms

Cell Reports Physical Science(2024)10.1016/j.xcrp.2024.101869

N/A

0DataRank · unranked

18 citations

Robert L. Beckman, Christina DeBarro, James E. Keener, Marcelo D. T. Torres, César de la Fuente‐Núñez +3 more

Influence of antimicrobial peptides on the bacterial membrane curvature and vice versa

Trends in Microbiology(2024)10.1016/j.tim.2024.04.012

N/A

0DataRank · unranked

17 citations

César de la Fuente‐Núñez, Nuno C. Santos, Michael Zasloff, Octávio Luiz Franco, Marlon H. Cardoso

Defensins identified through molecular de-extinction

Cell Reports Physical Science(2024)10.1016/j.xcrp.2024.102193

N/A

0DataRank · unranked

7 citations

Karen Ofuji Osiro, Kamila Botelho Sampaio de Oliveira, Marlon H. Cardoso, Lucas Rodrigues de Lima, Harry Morales Duque +5 more

Antibiofilm approaches as a new paradigm for treating infections

Progress in Biomedical Engineering(2024)10.1088/2516-1091/ad1cd6

N/A

0DataRank · unranked

5 citations

Yasser Dghoughi, Marius Colin, Marcelo D. T. Torres, César de la Fuente‐Núñez, Fany Reffuveille

Synthetic angiotensin II peptide derivatives confer protection against cerebral and severe non-cerebral malaria in murine models

Scientific Reports(2024)10.1038/s41598-024-51267-5

N/A

0DataRank · unranked

3 citations

Marcelo D. T. Torres, Leandro S. Silva, Flávio Lopes Alves, Antônio Miranda, Vani Xavier Oliveira +3 more

Design of multimodal antibiotics using deep learning

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.20.629780

N/A

0DataRank · unranked

5 citations

Fang Wan, Marcelo D. T. Torres, César de la Fuente‐Núñez, Angela Cesaro

Editorial: Machine learning approaches to antimicrobials: discovery and resistance

Frontiers in Bioinformatics(2024)10.3389/fbinf.2024.1458237

N/A

0DataRank · unranked

4 citations

Shirley W. I. Siu, César de la Fuente‐Núñez, Shira L. Broschat

Peptides from non-immune proteins target infections through antimicrobial and immunomodulatory properties

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.25.586636

N/A

0DataRank · unranked

0 citations

Angela Cesaro, César de la Fuente‐Núñez, Marcelo D. T. Torres

Challenges and applications of artificial intelligence in infectious diseases and antimicrobial resistance

npj Antimicrobials and Resistance(2025)10.1038/s44259-024-00068-x

N/A

0DataRank · unranked

89 citations

Samuel C. Hoffman, Payel Das, César de la Fuente‐Núñez, Angela Cesaro

AI-Driven Antimicrobial Peptide Discovery: Mining and Generation

Accounts of Chemical Research(2025)10.1021/acs.accounts.0c00594

N/A

0DataRank · unranked

69 citations

Wojciech Zarzecki, Jiejing Wang, Yiqian Duan, Jun Wang, Luís Pedro Coelho +3 more

AI Methods for Antimicrobial Peptides: Progress and Challenges

Microbial Biotechnology(2025)10.1111/1751-7915.70072

N/A

0DataRank · unranked

56 citations

Gary Liu, Jonathan M. Stokes, César de la Fuente‐Núñez, Carlos A. Brizuela

Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence

Nature Communications(2025)10.1038/s41467-025-60051-6

N/A

0DataRank · unranked

29 citations

Marcelo D. T. Torres, Sufen Li, César de la Fuente‐Núñez, Changge Guan

Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

Immunity(2025)10.1016/j.immuni.2025.06.006

N/A

0DataRank · unranked

18 citations

Kamen P. Simeonov, Walter K. Mowel, Michaël F. Michieletto, Leonel Joannas, Jasmine M. Wright +7 more

Generative latent diffusion language modeling yields anti-infective synthetic peptides

Cell Biomaterials(2025)10.1016/j.celbio.2025.100183

N/A

0DataRank · unranked

16 citations

Tianlai Chen, Fang Wan, Pranam Chatterjee, César de la Fuente‐Núñez, Marcelo D. T. Torres

Small and Versatile Cyclotides as Anti-infective Agents

ACS Infectious Diseases(2025)10.1021/acsinfecdis.4c00957

N/A

0DataRank · unranked

9 citations

Liryel Silva Gasparetto, Lívia V. Luchi, João Pedro Farias Pimentel, Marlon H. Cardoso, Maria Lígia Rodrigues Macedo +3 more

Frog-derived synthetic peptides display anti-infective activity against Gram-negative pathogens

Trends in biotechnology(2025)10.1016/j.tibtech.2025.02.007

N/A

0DataRank · unranked

9 citations

Andreia Boaro, Angela Cesaro, Marcelo D. T. Torres, Esther Broset, César de la Fuente‐Núñez +1 more

Essay: Using Machine Learning for Antibiotic Discovery

Physical Review Letters(2025)10.1103/y3fg-s9vg

N/A

0DataRank · unranked

9 citations

James J. Collins, César de la Fuente‐Núñez

Using synthetic biology to understand the gut-brain axis

Cell Reports Physical Science(2025)10.1016/j.xcrp.2025.102458

N/A

0DataRank · unranked

5 citations

Esther Broset, Gregory J. Salimando, Sebahat Öztekin, David Mai, Mariko L. Bennett +2 more

Exploring and expanding the chemical multiverse of peptides

Chemical Science(2025)10.1039/d5sc04465k

N/A

0DataRank · unranked

5 citations

Jean Paul Sánchez-Castañeda, Massyel S. Martínez-Cortés, César de la Fuente‐Núñez, José L. Medina‐Franco, Edgar López‐López

Tailored structured peptide design with a key-cutting machine approach

Nature Machine Intelligence(2025)10.1038/s42256-025-01119-2

N/A

0DataRank · unranked

4 citations

Marcelo D. T. Torres, Carlos A. Oliva, César de la Fuente‐Núñez, Carlos A. Brizuela, Yan Carlos Leyva

The Role of Asparagine as a Gatekeeper Residue in the Selective Binding of Rare Earth Elements by Lanthanide‐Binding Peptides

Chemistry - A European Journal(2025)10.1002/chem.202501318

N/A

0DataRank · unranked

3 citations

Baofu Qiao, Jason G. Marmorstein, Yiming Wang, Denize C. Favaro, Kathleen J. Stebe +8 more

Small but mighty: emerging roles of uORFs in plants

Trends in biotechnology(2025)10.1016/j.tibtech.2025.09.009

N/A

0DataRank · unranked

3 citations

Jianing Bai, César de la Fuente‐Núñez, Farhad Nazarian‐Firouzabadi

Synthetic peptides targeting a mast cell-specific G protein-coupled receptor MRGPRB2 display anti-infective potential

Cell Biomaterials(2025)10.1016/j.celbio.2025.100088

N/A

0DataRank · unranked

2 citations

Marcelo D. T. Torres, Rakesh Krishnan, César de la Fuente‐Núñez, Hydar Ali, Aetas Amponnawarat

The gut’s hidden arsenal: A genomics-guided atlas of class II bacteriocins

Cell Genomics(2025)10.1016/j.xgen.2025.101064

N/A

0DataRank · unranked

2 citations

César de la Fuente‐Núñez, Tianang Leng

Antiviral discovery using sparse datasets by integrating experiments, molecular simulations, and machine learning

Cell Reports Physical Science(2025)10.1016/j.xcrp.2025.102554

N/A

0DataRank · unranked

2 citations

Fang Wan, Haoyuan Shi, Kaiyang Wang, C. Mark Maupin, Matt L. Barker +5 more

Absence of gut microbiota restoration following meropenem treatment in a systemic infection model

npj Antimicrobials and Resistance(2025)10.1038/s44259-025-00129-9

N/A

0DataRank · unranked

2 citations

Camila Fontoura Acosta Ribeiro, Elizabete de Souza Cândido, Danieli Fernanda Buccini, Marlon H. Cardoso, Gislaine Greice de Oliveira Silva Silveira +13 more