Dario R. Alessi

MRC Protein Phosphorylation and Ubiquitylation Unit

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 20 papers. Top paper: “Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain”.

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

eLife(2021)10.7554/elife.67900

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2.1DataRank · unranked

107 citations

Yuriko Sobu, Herschel S. Dhekne, Francesca Tonelli, Kerryn Berndsen, Dario R. Alessi +2 more

Loss of primary cilia and dopaminergic neuroprotection in pathogenic LRRK2-driven and idiopathic Parkinson’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.15.575737

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0.711DataRank · unranked

21 citations

Ebsy Jaimon, Yu‐En Lin, Jonas Nikoloff, Francesca Tonelli, Dario R. Alessi +2 more

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.17.431620

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0DataRank · unranked

4 citations

Kerryn Berndsen, Paweł Lis, Axel Knebel, Yuko P. Y. Lam, Dario R. Alessi +2 more

Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase

Biochemical Journal(2022)10.1042/bcj20220019

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0DataRank · unranked

4 citations

Jinwei Zhang, Adrián Rafael Murillo‐de‐Ozores, María Castañeda‐Bueno, Francesca D’Amico, Raphael Heilig +9 more

Structural basis of human LRRK2 membrane recruitment and activation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.26.489605

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0DataRank · unranked

43 citations

Francesca Tonelli, Dario R. Alessi, Ji Sun, Hanwen Zhu

A mitochondrial blood-based patient stratification candidate biomarker for Parkinson’s disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.07.479309

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0DataRank · unranked

4 citations

Esther Sammler, Claudia P. González-Hunt, Nicholas Pena, Jeremy P. Rouanet, Steven D. Goodson +11 more

Golgi-IP, a novel tool for multimodal analysis of Golgi molecular content

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.22.517583

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0DataRank · unranked

3 citations

Wentao Dong, Raja Sekhar Nirujogi, Eshaan S. Rawat, Miharu Iguchi, Kwamina Nyame +6 more

A blood-based marker of mitochondrial DNA damage in Parkinson’s disease

Science Translational Medicine(2023)10.1126/scitranslmed.abo1557

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0DataRank · unranked

84 citations

Esther Sammler, Claudia P. González-Hunt, Ivana Barraza, Nicholas Pena, Jeremy P. Rouanet +24 more

Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2

Science(2023)10.1126/science.adi9926

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0DataRank · unranked

76 citations

Francesca Tonelli, Martin Turk, Alan R. Prescott, Dario R. Alessi, Ji Sun +1 more

Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

eLife(2023)10.7554/elife.87098

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0DataRank · unranked

74 citations

Francesca Tonelli, Wondwossen M Yeshaw, Claire Y Chiang, Charles Limouse, Ebsy Jaimon +4 more

Golgi-IP, a tool for multimodal analysis of Golgi molecular content

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219953120

N/A

0DataRank · unranked

69 citations

Wentao Dong, Raja Sekhar Nirujogi, Eshaan S. Rawat, Miharu Iguchi, Kwamina Nyame +6 more

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101244

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0DataRank · unranked

25 citations

Simone Lubrano, Michele Ceribelli, Damiano Cosimo Rigiracciolo, Robert Saddawi‐Konefka, Farhoud Faraji +18 more

Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.17.529028

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0DataRank · unranked

12 citations

Francesca Tonelli, Wondwossen M Yeshaw, Claire Y Chiang, Charles Limouse, Ebsy Jaimon +4 more

RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses

The Lancet Neurology(2024)10.1016/s1474-4422(24)00121-2

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0DataRank · unranked

110 citations

Jordan Follett, Joanne Trinh, Sandeep Kumar Barodia, Raquel Real, Zhiyong Liu +31 more

A pathogenic variant in RAB32 causes autosomal dominant Parkinson’s disease and activates LRRK2 kinase

medRxiv(2024)10.1101/2024.01.17.24300927

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0DataRank · unranked

3 citations

Jordan Follett, Joanne Trinh, Sandeep Kumar Barodia, Raquel Real, Zhiyong Liu +32 more

PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease

Cell Reports(2025)10.1016/j.celrep.2025.116031

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0DataRank · unranked

3 citations

Neringa Pratuseviciute, Yu‐En Lin, Ayan Adhikari, Wondwossen M Yeshaw, Chloe Flitton +19 more

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif

Structure(2025)10.1016/j.str.2025.11.003

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0DataRank · unranked

1 citations

Prosenjit Pal, Raja Sekhar Nirujogi, Melanie Cavin, Jaijeet Singh, Dario R. Alessi +2 more

Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2

Structure(2020)10.1016/j.str.2020.01.005

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0DataRank · unranked

94 citations

Elena Purlyte, Prosenjit Pal, Emma McGrath, Dario R. Alessi, Amir R. Khan +1 more

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.28.672006

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0DataRank · unranked

1 citations

Qianzi He, Giulia Tombesi, Eve Napier, Matthew Jaconelli, Oscar Andrés Moreno-Ramos +16 more

Structural basis for the specificity of PPM1H phosphatase for Rab GTPases

EMBO Reports(2021)10.15252/embr.202152675

N/A

0DataRank · unranked

29 citations

Kerryn Berndsen, Paweł Lis, Axel Knebel, Yuko P. Y. Lam, Dario R. Alessi +2 more