Catherine C.Y. Chang

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 14 papers. Top paper: “Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor”.

Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

Nature Communications(2020)10.1038/s41467-020-16288-4

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0DataRank · unranked

83 citations

Yange Niu, Si‐Cong Chen, Yunlu Kang, Jing-Xiang Wu, Koji Nishi +5 more

Nanodisc scaffold peptide (NSPr) replaces detergent by reconstituting acyl-CoA:cholesterol acyltransferase 1 into peptidiscs

Archives of Biochemistry and Biophysics(2020)10.1016/j.abb.2020.108518

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0DataRank · unranked

5 citations

Kevin Chao, Catherine C.Y. Chang, Ta‐Yuan Chang, Bryan Neumann

Inhibition mechanism of human sterol O-acyltransferase 1 by competitive inhibitor

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.07.897124

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0DataRank · unranked

2 citations

Yange Niu, Si‐Cong Chen, Yunlu Kang, Jing-Xiang Wu, Koji Nishi +5 more

Acat1 gene KO restores TGN cholesterol deficiency in mutant NPC1 cells and expands mutant Npc1 mouse lifespan

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.07.241471

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0DataRank · unranked

1 citations

Catherine C.Y. Chang, Robert A. Maue, Elaina M. Melton, Andrew A. Peden, William S. Garver +4 more

Blocking cholesterol storage to treat Alzheimer’s disease

Exploration of Neuroprotective Therapy(2021)10.37349/ent.2021.00014

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0DataRank · unranked

28 citations

Catherine C.Y. Chang, Taylor C. Harned, Adrianna L. De La Torre, Junghoon Lee, Thao N. Huynh +2 more

Facile method to incorporate high-affinity ACAT/SOAT1 inhibitor F12511 into stealth liposome-based nanoparticle and demonstration of its efficacy in blocking cholesteryl ester biosynthesis without overt toxicity in neuronal cell culture

Journal of Neuroscience Methods(2021)10.1016/j.jneumeth.2021.109437

N/A

0DataRank · unranked

11 citations

C G Smith, Joseph E. Granger, Faith L. Anderson, Taylor C. Harned, Matthew C. Havrda +3 more

Acute ACAT1/SOAT1 Blockade Increases MAM Cholesterol and Strengthens ER-Mitochondria Connectivity

International Journal of Molecular Sciences(2023)10.3390/ijms24065525

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0DataRank · unranked

36 citations

Radu V. Stan, Ze Cao, Rajarshi Chakrabarti, Henry N. Higgs, Catherine C.Y. Chang +2 more

ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-like Receptor 4 in Microglia

International Journal of Molecular Sciences(2023)10.3390/ijms24065616

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0DataRank · unranked

15 citations

Thao N. Huynh, Michael Tran Duong, James G. Gow, Catherine C.Y. Chang, Ta‐Yuan Chang +1 more

Stealth Liposomes Encapsulating a Potent ACAT1/SOAT1 Inhibitor F12511: Pharmacokinetic, Biodistribution, and Toxicity Studies in Wild-Type Mice and Efficacy Studies in Triple Transgenic Alzheimer’s Disease Mice

International Journal of Molecular Sciences(2023)10.3390/ijms241311013

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0DataRank · unranked

9 citations

Thao N. Huynh, Catherine C.Y. Chang, Darcy B. Pooler, Dylan B. Ness, Lionel D. Lewis +6 more

Stealth liposomes encapsulating a potent ACAT1/SOAT1 inhibitor F12511: pharmacokinetic, biodistribution and toxicity studies in wild-type mice, and efficacy studies in triple transgenic Alzheimer Disease mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.02.539100

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0DataRank · unranked

2 citations

Thao N. Huynh, Catherine C.Y. Chang, Darcy B. Pooler, Dylan B. Ness, Lionel D. Lewis +6 more

Inhibiting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Myelin Debris-Treated Microglial Cell Lines Activates the Gene Expression of Cholesterol Efflux Transporter ABCA1

Biomolecules(2024)10.3390/biom14101301

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0DataRank · unranked

15 citations

Matthew C. Havrda, George Zanazzi, Catherine C.Y. Chang, Ta‐Yuan Chang, Thao N. Huynh

Inhibiting the Cholesterol Storage Enzyme ACAT1/SOAT1 in Aging Apolipoprotein E4 Mice Alters Their Brains’ Inflammatory Profiles

International Journal of Molecular Sciences(2024)10.3390/ijms252413690

N/A

0DataRank · unranked

7 citations

Emma N. Fikse, Adrianna L. De La Torre, Matthew C. Havrda, Catherine C.Y. Chang, Ta‐Yuan Chang +1 more

Characterization of Stealth Liposome-Based Nanoparticles Encapsulating the ACAT1/SOAT1 Inhibitor F26: Efficacy and Toxicity Studies In Vitro and in Wild-Type Mice

International Journal of Molecular Sciences(2024)10.3390/ijms25179151

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0DataRank · unranked

2 citations

Adrianna L. De La Torre, Felix L. Rawlinson, Dylan B. Ness, Lionel D. Lewis, William F. Hickey +3 more

Unveiling interindividual variability in gut microbiota-mediated curcumin metabolism

Food Bioscience(2025)10.1016/j.fbio.2025.105941

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0DataRank · unranked

6 citations

Siu Ling Wong, Xu Chen, Zhihao Zhou, Hengjun Du, Yanhui Han +4 more