Ophir Shalem

Also affiliated with University of Pennsylvania

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing”.

Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing

Nature Human Behaviour(2020)10.1038/s41562-020-00944-2

N/A

6.7DataRank · unranked

129 citations

Han Altae-Tran, James Briggs, Xin Jin, Glen McGee, Andy Shi +33 more

High-resolution interrogation of functional elements in the noncoding genome

bioRxiv (Cold Spring Harbor Laboratory)(2016)10.1101/049130

N/A

1.4DataRank · unranked

28 citations

Jason Wright, Kaijie Zheng, Ophir Shalem, Pierre Fontanillas, Julia Joung +4 more

Building an international consortium for tracking coronavirus health status

Nature Medicine(2020)10.1038/s41591-020-0929-x

N/A

1.4DataRank · unranked

33 citations

Feng Zhang, Xihong Lin, Gary King, Ophir Shalem, Smadar Shilo +54 more

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks

Cell(2015)10.1016/j.cell.2015.06.059

N/A

0.918DataRank · unranked

455 citations

Marko Jovanovic, Rebecca H. Herbst, Atray Dixit, Chun Jimmie Ye, Dariusz Przybylski +13 more

Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing Identifies Contributors to Continued Disease Spread in the United States

medRxiv(2020)10.1101/2020.06.09.20126813

N/A

0.869DataRank · unranked

10 citations

Han Altae-Tran, James Briggs, Xin Jin, Glen McGee, Andy Shi +33 more

A framework for sharing of clinical and genetic data for precision medicine applications

Nature Medicine(2024)10.1038/s41591-024-03239-5

N/A

0.857DataRank · unranked

32 citations

Ulugbek K. Baymuradov, Hemali Phatnani, Justin Kwan, Dhruv Sareen, James R. Broach +63 more

Publisher Correction: Building an international consortium for tracking coronavirus health status

Nature Medicine(2020)10.1038/s41591-020-0983-4

N/A

0.788DataRank · unranked

1 citations

Feng Zhang, Xihong Lin, Gary King, Ophir Shalem, Smadar Shilo +54 more

Building an International Consortium for Tracking Coronavirus Health Status

medRxiv(2020)10.1101/2020.04.02.20051284

N/A

0.661DataRank · unranked

13 citations

Feng Zhang, Xihong Lin, Gary King, Ophir Shalem, Smadar Shilo +52 more

TDP-43 loss induces cryptic polyadenylation in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02050-w

N/A

0.593DataRank · unranked

23 citations

Anna‐Leigh Brown, Max Z. Y. J. Chien, Dario Dattilo, Puja R. Mehta, Francesca Mattedi +94 more

An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients

iScience(2021)10.1016/j.isci.2021.103221

N/A

0.593DataRank · unranked

51 citations

Justin Kwan, Dhruv Sareen, James R. Broach, Zachary Simmons, Ximena Arcila-Londono +92 more

Antisense oligonucleotide depletion of CCDC146 is a broad-spectrum therapeutic strategy for ALS

medRxiv(2024)10.1101/2024.03.30.24305115

N/A

0.278DataRank · unranked

5 citations

Tobias Moll, Jasper Rubin-Sigler, Sharon Tu, Shuya Li, Enming Yuan +29 more

Data from Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer

(2023)10.1158/0008-5472.c.6513802.v1

N/A

0DataRank · unranked

0 citations

Jinyang Li, Shivahamy Maheswaran, Robert J. Norgard, Salina Yuan, Maimon E. Hubbi +12 more

The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.28.568952

N/A

0DataRank · unranked

0 citations

Ava R. Hansen, Dylan Fingerman, Thi Tra My Tran, Brooke R. Harris, Katharina E. Hayer +13 more

KOLF2.1J iPSCs carry CNVs associated with neurodevelopmental disorders

Cell stem cell(2024)10.1016/j.stem.2024.02.007

N/A

0DataRank · unranked

18 citations

Jonathan E. Perdomo, Munir E. Khan, Thomas Roulé, Brianna Disanza, Gregory G. Cajka +12 more

Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons

Science Advances(2024)10.1126/sciadv.adj4767

N/A

0DataRank · unranked

17 citations

Nima Naseri, Sarshan R. Pather, Erinc Hallacli, Alain Ndayisaba, Chris Buenaventura +9 more

Pooled endogenous protein tagging and recruitment for systematic profiling of protein function

Cell Genomics(2024)10.1016/j.xgen.2024.100651

N/A

0DataRank · unranked

16 citations

Deepak Mani, Timothé Maujean, George M. Burslem, Ophir Shalem, Yevgeniy V. Serebrenik

The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress

The EMBO Journal(2024)10.1038/s44318-024-00137-x

N/A

0DataRank · unranked

12 citations

David R O’Leary, Ava R. Hansen, Thi Tran, Brooke R Harris, Rachel A. DeWeerd +15 more

CRISPR screen for protein inclusion formation uncovers a role for SRRD in the regulation of intermediate filament dynamics and aggresome assembly

PLoS Genetics(2024)10.1371/journal.pgen.1011138

N/A

0DataRank · unranked

5 citations

Sapanna Chantarawong, Edward M. Barbieri, Greg Cajka, Matthew Liu, Lynn A. Spruce +11 more

CRISPR associated enzymes are mislocalized to the cytoplasm in iPSC-derived neurons resulting in KRAB-specific degradation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.19.619045

N/A

0DataRank · unranked

3 citations

Matthew Liu, Ophir Shalem, Gregory Cajka

Intracellular Protein Editing to Enable Incorporation of Non-Canonical Residues into Endogenous Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.08.602493

N/A

0DataRank · unranked

0 citations

Yevgeniy V. Serebrenik, Kaitlyn Toy, Mohd Altaf Najar, Nicole R. Raniszewski, Ophir Shalem +2 more

Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

Molecular Cell(2025)10.1016/j.molcel.2025.04.002

N/A

0DataRank · unranked

7 citations

Yevgeniy V. Serebrenik, Tomer Lapidot, David G. Smith, George M. Burslem, Ophir Shalem +1 more

CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101408

N/A

0DataRank · unranked

2 citations

Sakshi Arora, Jonathan F. Lang, Beverly L. Davidson, Ophir Shalem, E. O'Driscoll

Therapeutic genetic variation revealed in diverse Hsp104 homologs

eLife(2020)10.7554/elife.57457

N/A

0DataRank · unranked

29 citations

Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M. Castellano, Meredith E. Jackrel +12 more

Therapeutic genetic variation revealed in diverse Hsp104 homologs

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.25.008748

N/A

0DataRank · unranked

2 citations

Katelyn Sweeney, Hanna Kim, Xiaohui Yan, Laura M. Castellano, Meredith E. Jackrel +10 more

Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization

Science Advances(2021)10.1126/sciadv.abj6818

N/A

0DataRank · unranked

15 citations

Ryo Higuchi‐Sanabria, C. Kimberly Tsui, Stefan Homentcovschi, Kevin M. Tharp, Hanlin Zhang +14 more

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature(2022)10.1038/s41586-022-04436-3

N/A

0DataRank · unranked

525 citations

Oscar G. Wilkins, Matthew J. Keuss, Sarah E. Hill, Matteo Zanovello, Weaverly Colleen Lee +90 more

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer

Cancer Research(2022)10.1158/0008-5472.can-22-0431

N/A

0DataRank · unranked

26 citations

Jinyang Li, Shivahamy Maheswaran, Robert J. Norgard, Salina Yuan, Maimon E. Hubbi +12 more

Large‐scale genetic screens identify BET‐1 as a cytoskeleton regulator promoting actin function and life span

Aging Cell(2022)10.1111/acel.13742

N/A

0DataRank · unranked

16 citations

Raz Bar‐Ziv, Maxim Averbukh, Nirmalya Dasgupta, Naibedya Dutta, Hanlin Zhang +12 more

Impaired ribosome-associated quality control of C9orf72 arginine-rich dipeptide-repeat proteins

Brain(2022)10.1093/brain/awac479

N/A

0DataRank · unranked

17 citations

Gregory Cajka, Olamide A. Olatunji, Bailey Mikytuck, Ophir Shalem, Edward B. Lee +1 more

A subpopulation of lipogenic brown adipocytes drives thermogenic memory

Nature Metabolism(2023)10.1038/s42255-023-00893-w

N/A

0DataRank · unranked

32 citations

Prateek Sharma, Lenka Dohnalová, Kyle Coleman, Giulia T. Uhr, Susanna Kircher +21 more

Pooled endogenous protein tagging and recruitment for scalable discovery of effectors for induced proximity therapeutics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.13.548759

N/A

0DataRank · unranked

5 citations

Deepak Mani, Timothé Maujean, George M. Burslem, Ophir Shalem, Yevgeniy V. Serebrenik

High density SNP array and reanalysis of genome sequencing uncovers CNVs associated with neurodevelopmental disorders in KOLF2.1J iPSCs

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.26.546614

N/A

0DataRank · unranked

4 citations

Jonathan E. Perdomo, Munir E. Khan, Brianna Disanza, Gregory G. Cajka, Sunyimeng Lei +12 more