🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Fengzhi Li

Roswell Park Comprehensive Cancer Center

ORCID: 0000-0002-2299-7951

Also affiliated with Zhejiang Provincial People's Hospital, Canget BioTekpharma (United States), Hangzhou Medical College, Anhui University of Technology

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile
0Author DataRank

Indexed papers

0in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 14 papers. Top paper: “Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer”.

Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer

Journal of Pharmaceutical Analysis(2024)10.1016/j.jpha.2024.101001
N/A
0.312DataRank · unranked
7 citations

Wenjie Wu, Li Yan, Leslie Curtin, Melanie M. Farrauto, Sandra Sexton +6 more

Sensitivity of colorectal or pancreatic cancers with high DDX5 and mutations in Kras and p53 genes to FL118 treatment.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e16102
N/A
0DataRank · unranked
2 citations

Wenjie Wu, Jianqun Liao, Sreevidya Santha, Leman Aljahdali, Jue Wang +5 more

Role of mutant KRAS as a biomarker in FL118-induced apoptosis, reactive oxygen species (ROS) production and inhibition of survivin, Mcl-1 and XIAP in human bladder cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.e15651
N/A
0DataRank · unranked
0 citations

Ieman Aljahdali, Sailee Rasam, Xue Wang, Xiang Ling, Jianqun Liao +6 more

Ultra-High-Resolution IonStar Strategy Enhancing Accuracy and Precision of MS1-Based Proteomics and an Extensive Comparison with State-of-the-Art SWATH-MS in Large-Cohort Quantification

Analytical Chemistry(2021)10.1021/acs.analchem.0c05002
N/A
0DataRank · unranked
21 citations

Liang Jin, Chenqi Hu, Shichen Shen, Shuo Qian, Min Ma +6 more

FL118, acting as a ‘molecular glue degrader’, binds to, dephosphorylates and degrades the oncoprotein DDX5 (p68) to control c‐Myc, survivin and mutant Kras against colorectal and pancreatic cancer with high efficacy

Clinical and Translational Medicine(2022)10.1002/ctm2.881
N/A
0DataRank · unranked
40 citations

Wenjie Wu, Ieman Aljahdali, Jianqun Liao, Sreevidya Santha, Christos Fountzilas +3 more

Depleting receptor tyrosine kinases EGFR and HER2 overcomes resistance to EGFR inhibitors in colorectal cancer

Journal of Experimental & Clinical Cancer Research(2022)10.1186/s13046-022-02389-z
N/A
0DataRank · unranked
31 citations

Arup Bhattacharya, Yun Li, Sandra Sexton, Xiang Ling, Fengzhi Li +2 more

Synthesis and biological evaluation of 20(S)-substituted FL118 conjugates as novel antitumor agents

Journal of Molecular Structure(2022)10.1016/j.molstruc.2022.133661
N/A
0DataRank · unranked
0 citations

Mengke Wang, Weitong Hu, Hanlin Yue, Endian Yu, Xiangli Zhang +7 more

Role of the DEAD-box RNA helicase DDX5 (p68) in cancer DNA repair, immune suppression, cancer metabolic control, virus infection promotion, and human microbiome (microbiota) negative influence

Journal of Experimental & Clinical Cancer Research(2023)10.1186/s13046-023-02787-x
N/A
0DataRank · unranked
44 citations

Xiang Ling, Sayan Chakraborty, Christos Fountzilas, Jianmin Wang, Anmbreen Jamroze +4 more

Single protein encapsulated SN38 for tumor-targeting treatment

Journal of Translational Medicine(2023)10.1186/s12967-023-04778-0
N/A
0DataRank · unranked
10 citations

Faqing Huang, Kinsley Wang, Mengmeng Liu, Warren Chow, Xiang Ling +6 more

Structure–Activity Relationship of FL118 Platform Position 7 Versus Position 9-Derived Compounds and Their Mechanism of Action and Antitumor Activity

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c01589
N/A
0DataRank · unranked
8 citations

Xiang Ling, Ruojiong Wang, Haonan Xiong, Liuzhi Hu, Zhikun Yang +8 more

Design, synthesis and investigation of biological activity and mechanism of fluoroaryl-substituted derivatives at the FL118 position 7

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.117143
N/A
0DataRank · unranked
7 citations

Ruojiong Wang, Lianhao An, Lei Li, Haonan Xiong, Fan Dong +9 more

FL496, an FL118-derived small molecule, induces growth inhibition, senescence, and apoptosis of malignant pleural mesothelioma (MPM) cells, and exhibits anti-MPM tumor efficacy strikingly superior to the pemetrexed-cisplatin combination

Journal of Experimental & Clinical Cancer Research(2025)10.1186/s13046-025-03547-9
N/A
0DataRank · unranked
2 citations

Xiang Ling, Wenjie Wu, Wenchao Wang, Dan Li, Renyuan Zhang +6 more

Mutant Kras as a Biomarker Plays a Favorable Role in FL118-Induced Apoptosis, Reactive Oxygen Species (ROS) Production and Modulation of Survivin, Mcl-1 and XIAP in Human Bladder Cancer

Cancers(2020)10.3390/cancers12113413
N/A
0DataRank · unranked
22 citations

Xiang Ling, Ieman Aljahdali, Sailee Rasam, Xue Wang, Jianqun Liao +6 more

Targeted Treatment of Sarcomas by Single Protein Encapsulated Doxorubicin with Undetectable Cardiotoxicity and Superior Efficacy

Cancers(2025)10.3390/cancers17050881
N/A
0DataRank · unranked
1 citations

Faqing Huang, Leslie Wang, Mengmeng Liu, Warren Chow, Xiang Ling +5 more