Matthew E. Hurles

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

160Author DataRank

Indexed papers

20in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 20 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Nature(2007)10.1038/nature05874

Top 1%

12.9DataRank

Top 1%5277 citations

J Stamatoyannopoulos, Simon G. Gregory, T Gingeras, Eoghan Harrington, Zhiping Weng +286 more

Papers

Driven by 67 papers — median percentile 98. Top paper: “Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project”.

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Nature(2007)10.1038/nature05874

Top 1%

12.9DataRank

Top 1%5277 citations

J Stamatoyannopoulos, Simon G. Gregory, T Gingeras, Eoghan Harrington, Zhiping Weng +286 more

Initial sequencing and comparative analysis of the mouse genome

Nature(2002)10.1038/nature01262

Top 1%

12.6DataRank

Top 1%7282 citations

Robert H. Waterston, Kerstin Lindblad‐Toh, Julien Lagarde, Josep F. Abril, PANKAJ AGARWAL +189 more

Sequencing and comparison of yeast species to identify genes and regulatory elements

Nature(2003)10.1038/nature01644

Top 1%

11.4DataRank

Top 1%1802 citations

Nick Patterson, Matthew Endrizzi, Matthew E. Hurles, Matthew G. Endrizzi, Bruce W. Birren +1 more

Comprehensive genomic characterization of squamous cell lung cancers

Nature(2012)10.1038/nature11404

Top 1%

11.0DataRank

Top 1%4036 citations

Gad Getz, Stephen E. Schumacher, Petar Stojanov, Chang‐Jiun Wu, Hailei Zhang +326 more

Transcriptional regulatory code of a eukaryotic genome

Nature(2004)10.1038/nature02800

Top 1%

10.6DataRank

Top 1%2201 citations

D. Benjamin Gordon, Tong Ihn Lee, Nicola J. Rinaldi, Kenzie D. Macisaac, Timothy W. Danford +21 more

A global reference for human genetic variation

Nature(2015)10.1038/nature15393

Top 1%

10.6DataRank

Top 1%20166 citations

Gonçalo R. Abecasis, Richard M. Durbin, Panagiotis Deloukas, Aravinda Chakravarti, Peter Donnelly +516 more

The Human Cell Atlas

Zurich Open Repository and Archive (University of Zurich)(2017)10.5167/uzh-162597

Top 1%

9.7DataRank

Top 1%1600 citations

Sarah A. Teichmann, Matthew E. Hurles, Ido Amit, Christophe Benoıst, Kerstin Lindblad‐Toh +3 more

Genome sequence, comparative analysis and haplotype structure of the domestic dog

Nature(2005)10.1038/nature04338

Top 2%

9.2DataRank

Top 2%2636 citations

Claire M. Wade, Tarjei S. Mikkelsen, Elinor K. Karlsson, David B. Jaffe, Michael Kamal +46 more

A brief history of human disease genetics

Nature(2020)10.1038/s41586-019-1879-7

N/A

9.2DataRank · unranked

738 citations

Judy H. Cho, Rory Collins, Nancy J. Cox, Emmanouil T. Dermitzakis, Matthew E. Hurles +13 more

A map of human genome variation from population-scale sequencing

Nature(2010)10.1038/nature09534

Top 2%

9.1DataRank

Top 2%8109 citations

Min Hu, Yuan Chen, Matthew N. Bainbridge, Richard M. Durbin, Si Quang Le +319 more

An integrated map of structural variation in 2,504 human genomes

Nature(2015)10.1038/nature15394

Top 2%

9.1DataRank

Top 2%2686 citations

Tobias Rausch, Marianne K. DeGorter, Robert E. Handsaker, Alexej Abyzov, Joanna M. M. Howson +75 more

A Draft Sequence of the Neandertal Genome

Science(2010)10.1126/science.1188021

Top 2%

8.6DataRank

Top 2%4581 citations

Johannes Krause, Adrian W. Briggs, Tomislav Maricic, Udo Stenzel, Martin Kircher +62 more

Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel

Nature Communications(2014)10.1038/ncomms4934

Top 2%

8.3DataRank

Top 2%460 citations

Jonathan Marchini, Peter Donnelly, Gerton Lunter, Jonathan L. Marchini, Simon Myers +364 more

Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype

Nature(2004)10.1038/nature03025

Top 2%

7.8DataRank

Top 2%2027 citations

Jean-Marc Aury, Frédéric Brunet, Jean-Louis Petit, Nicole Stange-Thomann, Evan Mauceli +69 more

A high-resolution map of human evolutionary constraint using 29 mammals

Nature(2011)10.1038/nature10530

Top 2%

7.6DataRank

Top 2%1227 citations

Genome Institute at Washington University, Manuel Garber, Or Zuk, Alireza Heravi-Moussavi, Wouter Meuleman +49 more

Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel

Nature Communications(2015)10.1038/ncomms9111

Top 3%

6.7DataRank

Top 3%386 citations

Bryan Howie, Shane McCarthy, Yasin Memari, Klaudia Walter, Josine L. Min +234 more

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Methods in Comparative Genomics: Genome Correspondence, Gene Identification and Regulatory Motif Discovery

Journal of Computational Biology(2004)10.1089/1066527041410319

N/A

5.0DataRank · unranked

105 citations

Nick Patterson, Bonnie Berger, Matthew E. Hurles, Bruce W. Birren, Sharon L. R. Kardia

A cross-disorder dosage sensitivity map of the human genome

Cell(2022)10.1016/j.cell.2022.06.036

Top 5%

4.7DataRank

Top 5%367 citations

Joseph Glessner, Eleonora Porcu, Maarja Lepamets, Rhonda Brandon, Christopher Lauricella +46 more

Efficient Generation of Transcriptomic Profiles by Random Composite Measurements

Cell(2017)10.1016/j.cell.2017.10.023

N/A

4.7DataRank · unranked

118 citations

Le Cong, Anthea Cheung, Matthew E. Hurles, Prisca Liberali, Brian Cleary

Similarities and differences in patterns of germline mutation between mice and humans

Nature Communications(2019)10.1038/s41467-019-12023-w

N/A

4.0DataRank · unranked

148 citations

Raheleh Rahbari, Joanna Kaplanis, Thomas Keane, Matthew E. Hurles, Sarah Lindsay

Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases

medRxiv(2020)10.1101/2020.09.08.20190561

N/A

3.4DataRank · unranked

132 citations

Jacob C. Ulirsch, Nathan Y. Cheng, Brian L. Trippe, Rebecca S. Fine, Jenkai Miao +24 more

Phylogenetically and spatially conserved word pairs associated with gene-expression changes in yeasts

Genome Biology(2003)10.1186/gb-2003-4-7-r43

N/A

3.1DataRank · unranked

55 citations

Alan M Moses, Sharon L. R. Kardia, Matthew E. Hurles, Michael B. Eisen, Derek Y. Chiang

Compressed sensing for highly efficient imaging transcriptomics

Nature Biotechnology(2021)10.1038/s41587-021-00883-x

N/A

2.8DataRank · unranked

49 citations

Brooke Simonton, Jon Bezney, Evan Murray, Shahul Alam, Anubhav Sinha +6 more

The Human Cell Atlas White Paper

arXiv (Cornell University)(2018)10.17863/cam.40032

Top 10%

2.2DataRank

Top 10%41 citations

Sarah A. Teichmann, Orit Rozenblatt‐Rosen, Michael J. T. Stubbington, Kristin G. Ardlie, Ido Amit +76 more

Prioritizing disease and trait causal variants at the TNFAIP3 locus using functional and genomic features

Nature Communications(2020)10.1038/s41467-020-15022-4

N/A

2.0DataRank · unranked

81 citations

Carl G. de Boer, Charles P. Fulco, Caleb A. Lareau, Masahiro Kanai, Jacob C. Ulirsch +12 more

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

bioRxiv (Cold Spring Harbor Laboratory)(2016)10.1101/054742

N/A

1.8DataRank · unranked

46 citations

Jonathan S. Gootenberg, Silvana Konermann, Julia Joung, Ian M. Slaymaker, David B.T. Cox +11 more

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Proceedings of the National Academy of Sciences(2005)10.1073/pnas.0506580102

N/A

1.6DataRank · unranked

55906 citations

Pablo Tamayo, Vamsi K. Mootha, Sayan Mukherjee, Benjamin L. Ebert, Michael A. Gillette +6 more

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Nature Genetics(2003)10.1038/ng1180

N/A

1.4DataRank · unranked

10534 citations

Cecilia M. Lindgren, Karl-Fredrik Eriksson, Aravind Subramanian, Smita Sihag, Joseph Lehar +19 more

Integrated genomic analyses of ovarian carcinoma

Nature(2011)10.1038/nature10166

N/A

1.3DataRank · unranked

8094 citations

Debra Bell, Andrew Berchuck, Michael J. Birrer, Jeremy Chien, D. W. Cramer +268 more

MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations

Genomics(1987)10.1016/0888-7543(87)90010-3

N/A

1.3DataRank · unranked

6696 citations

Philip Green, Jeff Abrahamson, Aaron Barlow, Coleen Damcott, Stephen E. Lincoln +2 more

The landscape of somatic copy-number alteration across human cancers

Nature(2010)10.1038/nature08822

N/A

1.2DataRank · unranked

4101 citations

Craig H. Mermel, Dale A. Porter, Guo Wei, Soumya Raychaudhuri, Jerry Donovan +61 more

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

Proceedings of the National Academy of Sciences(2009)10.1073/pnas.0904715106

N/A

1.2DataRank · unranked

2859 citations

Mitchell Guttman, Maite Huarte, Manuel Garber, Arjun Raj, Dianali Rivea Morales +8 more

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

Proceedings of the National Academy of Sciences(2001)10.1073/pnas.191502998

N/A

1.2DataRank · unranked

2583 citations

William G. Richards, Jane Staunton, Cheng Li, Stefano Monti, Priya Vasa +16 more

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Nature(2008)10.1038/nature07107

N/A

1.2DataRank · unranked

2535 citations

Tarjei S. Mikkelsen, Hongcang Gu, Marius Wernig, Sachet A. Shukla, Xiaolan Zhang +8 more

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

Science(2011)10.1126/science.1208130

N/A

1.2DataRank · unranked

2533 citations

Ann Marie Egloff, Aaron D. Tward, Aleksandar D. Kostic, Kristian Cibulskis, Sachet A. Shukla +38 more

A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

Cell(2010)10.1016/j.cell.2010.06.040

N/A

1.1DataRank · unranked

2079 citations

Mitchell Guttman, David Feldser, Manuel Garber, Magdalena J. Koziol, Daniela Kenzelmann-Broz +11 more

Multiclass cancer diagnosis using tumor gene expression signatures

Proceedings of the National Academy of Sciences(2001)10.1073/pnas.211566398

N/A

1.1DataRank · unranked

2044 citations

Pablo Tamayo, Ryan Rifkin, Sayan Mukherjee, Chen-Hsiang Yeang, Michael Angelo +12 more

lincRNAs act in the circuitry controlling pluripotency and differentiation

Nature(2011)10.1038/nature10398

N/A

1.1DataRank · unranked

1897 citations

Julie Donaghey, Bryce W. Carey, Manuel Garber, Jennifer K. Grenier, Glen Munson +13 more

Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae

Nature(2004)10.1038/nature02424

N/A

1.1DataRank · unranked

1554 citations

Bruce W. Birren, Matthew E. Hurles, Sharon L. R. Kardia

Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing

Nature Biotechnology(2009)10.1038/nbt.1523

N/A

1.1DataRank · unranked

1502 citations

Alexandre Melnikov, Jared Maguire, Peter Rogov, Emily M LeProust, William Brockman +11 more

Initial genome sequencing and analysis of multiple myeloma

Nature(2011)10.1038/nature09837

N/A

1.1DataRank · unranked

1438 citations

Michael S. Lawrence, Jonathan J. Keats, Kristian Cibulskis, Carrie Sougnez, Anna C. Schinzel +51 more

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial

Nature(2018)10.1038/s41586-018-0792-9

N/A

1.1DataRank · unranked

1412 citations

Jing Sun, Itay Tirosh, Nathan D. Mathewson, Shuqiang Li, Giacomo Oliveira +51 more

A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

Science(2012)10.1126/science.1215040

N/A

1.1DataRank · unranked

1321 citations

Suganthi Balasubramanian, Michael G. FitzGerald, Ni Huang, James Morris, Fred R. Hirsch +54 more

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

Nature Biotechnology(2010)10.1038/nbt.1633

N/A

1.1DataRank · unranked

1265 citations

Manuel Garber, Joshua Z. Levin, Julie Donaghey, James Robinson, Xian Adiconis +9 more

The genomic complexity of primary human prostate cancer

Nature(2011)10.1038/nature09744

N/A

1.1DataRank · unranked

1250 citations

Michael S. Lawrence, Francesca Demichelis, Timothy R. Dreszer, Kristian Cibulskis, Sachet A. Shukla +36 more

Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites

Cell Reports(2014)10.1016/j.celrep.2014.05.048

N/A

1.1DataRank · unranked

1246 citations

Maxwell R. Mumbach, Marko Jovanovic, Timothy Wang, Karolina Maciag, G. Guy Bushkin +16 more

The genetic architecture of type 2 diabetes

Nature(2016)10.1038/nature18642

N/A

1.1DataRank · unranked

1106 citations

Menachem Fromer, Tanya M. Teslovich, Anubha Mahajan, Vineeta Agarwala, Kyle J. Gaulton +334 more

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Proceedings of the National Academy of Sciences(2007)10.1073/pnas.0710052104

N/A

1.0DataRank · unranked

1085 citations

Gad Getz, Leia Nghiemphu, Jordi Barretina, Teli Hsueh, David Linhart +31 more

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

Nature Biotechnology(2012)10.1038/nbt.2137

N/A

0.978DataRank · unranked

677 citations

Anand Murugan, Xiaolan Zhang, Tiberiu Tesileanu, Li Wang, Peter Rogov +9 more

High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis

Cell(2013)10.1016/j.cell.2013.10.047

N/A

0.971DataRank · unranked

647 citations

Sudeep D. Agarwala, Maxwell R. Mumbach, Marko Jovanovic, Philipp Mertins, Alexander A. Shishkin +10 more

Bayesian refinement of association signals for 14 loci in 3 common diseases

Nature Genetics(2012)10.1038/ng.2435

N/A

0.947DataRank · unranked

552 citations

Jake Byrnes, Damjan Vukcevic, Kimmo Palin, Zhan Su, Joanna M. M. Howson +35 more

Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis

Cell(2018)10.1016/j.cell.2018.02.036

N/A

0.909DataRank · unranked

426 citations

Mathias Munschauer, Jacob C. Ulirsch, Claudia Fiorini, Leif S. Ludwig, Merry-Lynn McDonald +24 more

Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

Proceedings of the National Academy of Sciences(2007)10.1073/pnas.0701811104

N/A

0.864DataRank · unranked

316 citations

Tarjei S. Mikkelsen, Andreas Gnirke, Broad Institute Sequencing Platform and Whole Genome Assembly Team, Sharon L. R. Kardia, Matthew E. Hurles +2 more