Daohong Zhou

The University of Texas at San Antonio Health Science Center

Also affiliated with The University of Texas at San Antonio

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Supplementary Table from A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22432374.v1

Top 100%

0DataRank

Top 100%0 citations

Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu +21 more

Papers

Driven by 66 papers — median percentile 0. Top paper: “Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice”.

Increased marrow adipogenesis does not contribute to age‐dependent appendicular bone loss in female mice

Aging Cell(2020)10.1111/acel.13247

N/A

1.3DataRank · unranked

35 citations

Ha‐Neui Kim, Li Han, Daohong Zhou, Jeff Thostenson, Ryan M. Porter +4 more

Osteocyte RANKL is required for cortical bone loss with age and is induced by senescence

JCI Insight(2020)10.1172/jci.insight.138815

N/A

0.708DataRank · unranked

111 citations

Jinhu Xiong, Ryan S. MacLeod, Srividhya Iyer, Yuko Fujiwara, Keisha M. Cawley +9 more

Senolytic treatment alleviates doxorubicin‐induced chemobrain

Aging Cell(2024)10.1111/acel.14037

N/A

0.505DataRank · unranked

28 citations

Ashok Kumar, Asha Rani, Sahana Manohar Sindhu, Yang Yang, Daohong Zhou +2 more

First in human phase 1 study of DT2216, a selective BCL-xL degrader, in patients with relapsed/refractory solid malignancies

Journal of Hematology & Oncology(2025)10.1186/s13045-025-01753-8

N/A

0.436DataRank · unranked

14 citations

Minal Barve, Devalingam Mahalingam, Jay Parekh, Michael R. Kurman, James Strauss +10 more

PSPC1 exerts an oncogenic role in AML by regulating a leukemic transcription program in cooperation with PU.1

Cell stem cell(2025)10.1016/j.stem.2025.01.010

N/A

0.396DataRank · unranked

13 citations

Pinpin Sui, Ying Li, Kaiyu Xu, Ji‐Hoon Lee, Juan Wang +20 more

Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-X L degradation to overcome cancer chemoresistance

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.24.661170

N/A

0.373DataRank · unranked

11 citations

Adam Presser, Lissah Johnson, Yusuke Matoba, Brendan Shay, Weiyi Xu +19 more

Sexual dimorphism in the mouse bone marrow niche regulates hematopoietic engraftment via sex-specific Kdm5c/Cxcl12 signaling

Journal of Clinical Investigation(2025)10.1172/jci182125

N/A

0.360DataRank · unranked

10 citations

Liming Hou, Bowen Yan, Jinpeng Liu, Cuiping Zhang, Pinpin Sui +8 more

A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR

Neoplasia(2024)10.1016/j.neo.2024.101070

N/A

0.330DataRank · unranked

8 citations

Gerik W. Tushoski-Alemán, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Zhiguang Huo +6 more

PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.27.582353

N/A

0.312DataRank · unranked

7 citations

Lin Cao, J Wiegand, Peiyi Zhang, Maria Zajac‐Kaye, Frederic J. Kaye +3 more

PROTACs are effective in addressing the platelet toxicity associated with BCL-XL inhibitors

Exploration of Targeted Anti-tumor Therapy(2020)10.37349/etat.2020.00017

N/A

0DataRank · unranked

23 citations

Xuan Zhang, Xingui Liu, Sajid Khan, Daohong Zhou, Guangrong Zheng +1 more

Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse

UNC Libraries(2020)10.17615/3s83-jf70

N/A

0DataRank · unranked

0 citations

Shani Alston, Monique N. O’Leary, Daohong Zhou, Allison M. Deal, Alexis Valdovinos +17 more

Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity,

Nature Communications(2021)10.1038/s41467-021-27210-x

N/A

0DataRank · unranked

149 citations

Pratik Pal, Xingui Liu, Yannan Jia, Dinesh Thummuri, Peiyi Zhang +19 more

CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells

Nature Communications(2021)10.1038/s41467-021-26091-4

N/A

0DataRank · unranked

129 citations

Nicholas Borcherding, Kawther Khalid Ahmed, Andrew P. Voigt, Ajaykumar Vishwakarma, Ryan Kolb +30 more

Overcoming Gemcitabine Resistance in Pancreatic Cancer Using the BCL-XL–Specific Degrader DT2216

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-21-0474

N/A

0DataRank · unranked

74 citations

Sajid Khan, Patrick W. Underwood, Peiyi Zhang, J Wiegand, Xuan Zhang +13 more

Cellular senescence in lymphoid organs and immunosenescence

Aging(2021)10.18632/aging.203405

N/A

0DataRank · unranked

66 citations

Thomas C. Foster, Daohong Zhou, Vivekananda Budamagunta

Senescence-associated hyper-activation to inflammatory stimuli in vitro

Aging(2021)10.18632/aging.203396

N/A

0DataRank · unranked

58 citations

Sahana Manohar‐Sindhu, Yang Yang, Yonghan He, Dmitry O. Traktuev, Thomas C. Foster +2 more

Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells

Nature Communications(2021)10.1038/s41467-021-21573-x

N/A

0DataRank · unranked

55 citations

Umasankar De, Sajid Khan, Yuewan Luo, Myung‐Chul Kim, Haijun Yu +14 more

Dietary Methionine Deficiency Enhances Genetic Instability in Murine Immune Cells

International Journal of Molecular Sciences(2021)10.3390/ijms22052378

N/A

0DataRank · unranked

11 citations

Ratan Sadhukhan, Isabelle R. Miousse, Sarita Garg, Igor Koturbash, Daohong Zhou +3 more

Hem1 promotes osteoclast fusion and bone resorption in mice

Research Square(2021)10.21203/rs.3.rs-763477/v1

N/A

0DataRank · unranked

0 citations

Lijian Shao, Aaron Warren, Kimberly J. Krager, Nükhet Aykin‐Burns, Robert Hromas +4 more

BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers

Journal of Hematology & Oncology(2022)10.1186/s13045-022-01241-3

N/A

0DataRank · unranked

61 citations

J Wiegand, Peiyi Zhang, Wanyi Hu, Dinesh Thummuri, Vivekananda Budamagunta +9 more

A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer

Cancer Research(2022)10.1158/0008-5472.can-22-0698

N/A

0DataRank · unranked

27 citations

Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu +21 more

Targeting BCL-XL in fibrolamellar hepatocellular carcinoma

JCI Insight(2022)10.1172/jci.insight.161820

N/A

0DataRank · unranked

27 citations

Denise Ng, Gadi Lalazar, Carly Rosemore, Tova M. Finkelstein, Rachael D. Migler +13 more

Resistance to the BCL-XL degrader DT2216 in T-cell acute lymphoblastic leukemia is rare and correlates with decreased BCL-XL proteolysis

Cancer Chemotherapy and Pharmacology(2022)10.1007/s00280-022-04490-8

N/A

0DataRank · unranked

19 citations

Aruna S. Jaiswal, Elizabeth A. Williamson, Jonathon Gelfond, Guangrong Zheng, Daohong Zhou +2 more

Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102841

N/A

0DataRank · unranked

5 citations

Lijian Shao, Kimberly Richardson, Wen Ling, Aaron Warren, Kimberly J. Krager +6 more

Piperlongumine (PL) conjugates induce targeted protein degradation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.21.474712

N/A

0DataRank · unranked

6 citations

Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan +12 more

Co-targeting BCL-X L and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.12.507616

N/A

0DataRank · unranked

0 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity

JCI Insight(2023)10.1172/jci.insight.166643

N/A

0DataRank · unranked

113 citations

Man J. Livingston, Zhengwei Ma, Xiaoru Hu, Lu Wen, Han‐Fei Ding +3 more

Piperlongumine conjugates induce targeted protein degradation

Cell chemical biology(2023)10.1016/j.chembiol.2023.01.004

N/A

0DataRank · unranked

71 citations

Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan +12 more

Co-targeting BCL-XL and BCL-2 by PROTAC 753B eliminates leukemia cells and enhances efficacy of chemotherapy by targeting senescent cells

Haematologica(2023)10.3324/haematol.2022.281915

N/A

0DataRank · unranked

68 citations

Lina Han, Cassandra L. Ramage, Zhe Wang, Connie C. Weng, Lei Yang +15 more

Structural insights into BCDX2 complex function in homologous recombination

Nature(2023)10.1038/s41586-023-06219-w

N/A

0DataRank · unranked

52 citations

Lijia Jia, Aviv Meir, Shuo Zhou, Hardeep Kaur, Eliza A. Ruben +14 more

Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice

Cell Death Discovery(2023)10.1038/s41420-022-01296-8

N/A

0DataRank · unranked

43 citations

Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang +14 more

Targeting KRAS in pancreatic cancer: Emerging therapeutic strategies

Advances in cancer research(2023)10.1016/bs.acr.2023.02.004

N/A

0DataRank · unranked

19 citations

Vivekananda Budamagunta, Daohong Zhou, Sajid Khan

TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells

Nucleic Acids Research(2023)10.1093/nar/gkad952

N/A

0DataRank · unranked

15 citations

Arijit Dutta, Gayathri Srinivasan, Yaxia Yuan, Daohong Zhou, Montaser Shaheen +14 more

PELP1 inhibition by SMIP34 reduces endometrial cancer progression via attenuation of ribosomal biogenesis

Molecular Oncology(2023)10.1002/1878-0261.13539

N/A

0DataRank · unranked

5 citations

Zexuan Liu, Weiwei Tang, Uday P. Pratap, Alexia B. Collier, Kristin A. Altwegg +12 more

Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome

Radiation Research(2023)10.1667/rade-22-00208.1

N/A

0DataRank · unranked

7 citations

Louis M. Pelus, P. Artur Plett, Carol H. Sampson, Hui Lin Chua, Alexa Fisher +15 more

Latexin deletion protects against radiation-induced hematopoietic damages via selective activation of Bcl-2 prosurvival pathway

Haematologica(2023)10.3324/haematol.2022.282028

N/A

0DataRank · unranked

4 citations

Xiaojing Cui, Yi Liu, Fang Wang, Robert Signer, Kapana Nattamai +6 more

Design and optimization of piperlongumine analogs as potent senolytics

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129593

N/A

0DataRank · unranked

4 citations

Yonghan He, Xingui Liu, Xin Zhang, Peizhong Shi, Yingying Wang +3 more

Supplementary Table from A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer

INDIGO (University of Illinois at Chicago)(2023)10.1158/0008-5472.22432374.v1

Top 100%

0DataRank

Top 100%0 citations

Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu +21 more

Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.09.552650

N/A

0DataRank · unranked

0 citations

Yufeng Xiao, Yuewan Luo, Rohan Master, Jiao Mo, Myung‐Chul Kim +11 more

MiR-223-3p promotes genomic stability of hematopoietic progenitors after radiation

Experimental Hematology(2023)10.1016/j.exphem.2023.10.002

N/A

0DataRank · unranked

0 citations

Gayathri Srinivasan, Aruna S. Jaiswal, Elizabeth A. Williamson, Lingxiao Li, Dominic Arris +4 more

Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL

Nature Communications(2024)10.1038/s41467-024-46922-4

N/A

0DataRank · unranked

49 citations

Dongwen Lv, Yaxia Yuan, Peiyi Zhang, Wanyi Hu, Anindita Nayak +8 more

Promotion of DNA end resection by BRCA1–BARD1 in homologous recombination

Nature(2024)10.1038/s41586-024-07910-2

N/A

0DataRank · unranked

35 citations

James M. Daley, Hardeep Kaur, Nozomi Tomimatsu, Chaoyou Xue, Vivek B. Raina +24 more

Targeted Protein Degradation: Current and Emerging Approaches for E3 Ligase Deconvolution

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c00723

N/A

0DataRank · unranked

33 citations

Yaxia Yuan, Yi Liu, Zongtao Lin, Guangrong Zheng, Daohong Zhou +2 more

PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer

Cells(2024)10.3390/cells13060528

N/A

0DataRank · unranked

29 citations

Lin Cao, J Wiegand, Peiyi Zhang, Maria Zajac‐Kaye, Frederic J. Kaye +3 more

PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy

The Journal of Experimental Medicine(2024)10.1084/jem.20231519

N/A

0DataRank · unranked

28 citations

Yufeng Xiao, Yuewan Luo, Rohan Master, Jiao Mo, Myung‐Chul Kim +17 more

Radiation Biological Toximetry Using Circulating Cell-Free DNA (cfDNA) for Rapid Radiation/Nuclear Triage

Radiation Research(2024)10.1667/rade-23-00159.1

N/A

0DataRank · unranked

4 citations

Steven G Swarts, Bruce M. Fenton, Steven B. Zhang, Zhenhuan Zhang, Lori Rice +4 more

Mechanism of SETX-BRCA1-BARD1 complex in resolution of R-loops and transcription-replication conflicts

Research Square(2024)10.21203/rs.3.rs-3833044/v1

N/A

0DataRank · unranked

5 citations

Arijit Dutta, Jae‐Hoon Ji, Qingming Fang, Shuo Zhou, Fengshan Liang +22 more

Targeted inhibition of Bcl-xL following radiation reduces tumourigenesis in preclinical models of H3K27M-altered diffuse midline glioma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.20.629607

N/A

0DataRank · unranked

0 citations

Scott Haston, Romain Guiho, Diana Carvahlo, Rebecca Carter, Jessica K.R. Boult +21 more

CD36-mediated endocytosis of proteolysis-targeting chimeras

Cell(2025)10.1016/j.cell.2025.03.036

N/A

0DataRank · unranked

50 citations

Bo‐Syong Pan, Rajesh Manne, Jungang Chen, Dongwen Lv, Minmin Wang +13 more

A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice

Nature Aging(2025)10.1038/s43587-025-00811-7

N/A

0DataRank · unranked

48 citations

Natacha Jn-Simon, Yonghan He, Chunbao Sun, Peiyi Zhang, Wanyi Hu +11 more

Mitochondrial ACSS1-K635 acetylation knock-in mice exhibit altered liver lipid metabolism on a ketogenic diet

Free Radical Biology and Medicine(2025)10.1016/j.freeradbiomed.2025.03.009

N/A

0DataRank · unranked

7 citations

Joseph Schell, Songhua Quan, Yucheng Gao, Sung‐Jen Wei, Meixia Pan +9 more

Discovery of XZ338, a highly potent BCL-XL degrader

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117624

N/A

0DataRank · unranked

5 citations

Dinesh Thummuri, Wanyi Hu, Xingui Liu, Peiyi Zhang, Shuo Zhou +3 more

Discovery of PZ671, a highly potent and in vivo active CRBN-recruiting Bcl-xL degrader

RSC Medicinal Chemistry(2025)10.1039/d5md00119f

N/A

0DataRank · unranked

3 citations

Dinesh Thummuri, Wanyi Hu, Sajid Khan, Yonghan He, Xuan Zhang +5 more

Navitoclax acts synergistically with irradiation to induce apoptosis in preclinical models of H3K27M-altered diffuse midline glioma

Scientific Reports(2025)10.1038/s41598-025-32676-6

N/A

0DataRank · unranked

1 citations

Scott Haston, Hiba Hamdi, Grace Cooksley, Romain Guiho, Diana Martins Carvalho +22 more

Unveiling BCL-xL-specific PROTAC Efficiency and Dissociation Mechanisms Using Native Mass Spectrometry

ChemRxiv(2025)10.26434/chemrxiv-2025-zfjsj

N/A

0DataRank · unranked

1 citations

Kailyn L. Nonhof, Digant Nayak, Peiyi Zhang, Olivia E. Dioli, Guangrong Zheng +4 more

NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.29.651251

N/A

0DataRank · unranked

0 citations

Michael H. Nipper, Angel A. Dominguez, Chenhui He, Francis E. Sharkey, Sajid Khan +7 more

Using proteolysis-targeting chimera technology to reduce navitoclax platelet toxicity and improve its senolytic activity

Nature Communications(2020)10.1038/s41467-020-15838-0

N/A

0DataRank · unranked

260 citations

Xuan Zhang, Jianhui Chang, Ha‐Neui Kim, Peiyi Zhang, Yingying Wang +17 more

Single-Assay Characterization of Ternary Complex Assembly and Activity in Targeted Protein Degradation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.20.671298

N/A

0DataRank · unranked

0 citations

Vi Dougherty, Dongwen Lv, Pirouz Ebadi, Shikha Dubey, Digant Nayak +5 more

IL-17 and immunologically induced senescence regulate response to injury in osteoarthritis

Journal of Clinical Investigation(2020)10.1172/jci134091

N/A

0DataRank · unranked

257 citations

Hong Zhang, Jin Han, Matthew T. Wolf, Ok Hee Jeon, Kaitlyn Sadtler +11 more

DT2216—a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00928-9

N/A

0DataRank · unranked

134 citations

Raphael Koch, Vivekananda Budamagunta, Peiyi Zhang, Xuan Zhang, Sajid Khan +11 more

Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies

Journal of Hematology & Oncology(2020)10.1186/s13045-020-00924-z

N/A

0DataRank · unranked

123 citations

Sajid Khan, Zhiguang Huo, Dongwen Lv, Xuan Zhang, Xingui Liu +6 more

Discovery of PROTAC BCL-XL degraders as potent anticancer agents with low on-target platelet toxicity

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112186

N/A

0DataRank · unranked

115 citations

Dinesh Thummuri, Xingui Liu, Wanyi Hu, Peiyi Zhang, Sajid Khan +4 more

Depletion of senescent-like neuronal cells alleviates cisplatin-induced peripheral neuropathy in mice

Scientific Reports(2020)10.1038/s41598-020-71042-6

N/A

0DataRank · unranked

73 citations

Manchao Zhang, Wuying Du, Xin Zhao, Matthew Plotkin, Jianhui Chang +4 more

Discovery of IAP-recruiting BCL-XL PROTACs as potent degraders across multiple cancer cell lines

European Journal of Medicinal Chemistry(2020)10.1016/j.ejmech.2020.112397

N/A

0DataRank · unranked

65 citations

Yonghan He, Peiyi Zhang, Vivekananda Budamagunta, Dongwen Lv, Dinesh Thummuri +6 more

FoxM1 insufficiency hyperactivates Ect2–RhoA–mDia1 signaling to drive cancer

Nature Cancer(2020)10.1038/s43018-020-00116-1

N/A

0DataRank · unranked

14 citations

Karthik B. Jeganathan, Jake A. Kloeber, Brian A. Davies, Cheng Zhang, Ines Sturmlechner +10 more

Deuteration of the farnesyl terminal methyl groups of δ-tocotrienol and its effects on the metabolic stability and ability of inducing G-CSF production

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115498

N/A

0DataRank · unranked

8 citations

Zhengya Gao, Qiang Fu, Lin Song, Peiyi Zhang, Xuan Zhang +5 more

Daohong Zhou

Indexed papers

Top data-sharing exemplar

Papers