Christopher Aiken

Immunology and MicrobiologyMedicineEnvironmental ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

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Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 33 papers. Top paper: “Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis”.

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

PLoS Biology(2020)10.1371/journal.pbio.3001015

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72 citations

D Fischer, Sanela Rankovic, Wen Li, Robert A. Dick, Brent Runge +9 more

SERINC5 Inhibits HIV-1 Infectivity by Altering the Conformation of gp120 on HIV-1 Particles

Journal of Virology(2020)10.1128/jvi.00594-20

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25 citations

Christopher Aiken, Austin Featherstone

Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding

UNC Libraries(2020)10.17615/2304-bd59

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1 citations

Jason Concel, Joanne I. Yeh, Haibin Shi, Peijun Zhang, Laurie Betts +4 more

Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.30.071217

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14 citations

D Fischer, Sanela Rankovic, Wen Li, Rob Dick, Brent Runge +9 more

A DNA-origami nuclear pore mimic reveals nuclear entry mechanisms of HIV-1 capsid

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.10.245522

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6 citations

Chaoyi Xu, Sooin Jang, Qiancheng Xiong, Swapnil C. Devarkar, Taoran Tian +13 more

Chemical Stabilization of the HIV-1 Capsid Results in Efficient HIV-1 Reverse Transcription in vitro

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.17.302315

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1 citations

Jiong Shi, Janani Varadarajan, Parker J. Jamieson, Christopher Aiken, Jordan Jennings

CryoET structures of immature HIV Gag reveal a complete six-helix bundle and stabilizing small molecules distinct from IP6

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.31.363382

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1 citations

Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek +9 more

CryoET structures of immature HIV Gag reveal six-helix bundle

Communications Biology(2021)10.1038/s42003-021-01999-1

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58 citations

Dapeng Sun, Jiying Ning, Jiwei Liu, Abhay Kotecha, Mateusz Olek +9 more

The HIV-1 capsid and reverse transcription

Retrovirology(2021)10.1186/s12977-021-00566-0

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52 citations

Itay Rousso, Christopher Aiken

HIV-1 Uncoating Occurs via a Series of Rapid Biomechanical Changes in the Core Related to Individual Stages of Reverse Transcription

Journal of Virology(2021)10.1128/jvi.00166-21

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43 citations

Akshay Deshpande, Shimon Harel, Christopher Aiken, Itay Rousso, Sanela Rankovic

Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells

PLoS Pathogens(2021)10.1371/journal.ppat.1009190

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29 citations

Christopher Aiken, Gregory A. Sowd

HIV-1 CA Inhibitors Are Antagonized by Inositol Phosphate Stabilization of the Viral Capsid in Cells

Journal of Virology(2021)10.1128/jvi.01445-21

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20 citations

Jiong Shi, Christopher Aiken, Gregory A. Sowd

Correction: Inositol phosphates promote HIV-1 assembly and maturation to facilitate viral spread in human CD4+ T cells

PLoS Pathogens(2021)10.1371/journal.ppat.1009389

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9 citations

Christopher Aiken, Gregory A. Sowd

HIV-1 uncoating occurs via a series of rapid biomechanical changes in the core related to individual stages of reverse transcription

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.16.426924

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7 citations

Akshay Deshpande, Shimon Harel, Christopher Aiken, Itay Rousso, Sanela Rankovic

HIV-1 Mutants that Escape the Cytotoxic T-Lymphocytes are Defective in Viral DNA Integration

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.29.458043

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0 citations

Santosh Thapa, Benem-Orom Davids, Alex Bryer, Chaoyi Xu, Jiong Shi +5 more

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

PLoS Pathogens(2022)10.1371/journal.ppat.1010754

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26 citations

Anna Cereseto, Parmit K. Singh, Jiong Shi, Eric M. Poeschla, Alan Engelman +3 more

HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration

PNAS Nexus(2022)10.1093/pnasnexus/pgac064

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14 citations

Benem-Orom Davids, Alex Bryer, Chaoyi Xu, Santosh Thapa, Jiong Shi +5 more

Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels

Nature Structural & Molecular Biology(2023)10.1038/s41594-023-00925-9

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53 citations

Qingzhou Feng, Chunxiang Wu, Qiancheng Xiong, Taoran Tian, Shuai Yuan +9 more

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2202815120

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46 citations

Sushila Kumari, Chaoyi Xu, Sooin Jang, Jiong Shi, Ryan C. Burdick +18 more

Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization

Nature Communications(2023)10.1038/s41467-023-41197-7

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20 citations

Karen A. Kirby, William M. McFadden, Haijuan Du, Dandan Liu, Chaoyi Xu +10 more

HIV-1 capsid stability enables inositol phosphate-independent infection of target cells and promotes integration into genes

PLoS Pathogens(2023)10.1371/journal.ppat.1011423

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17 citations

Jiong Shi, Ashley N. Fulmer, Christopher Aiken, Gregory A. Sowd

Elasticity of the HIV-1 Core Facilitates Nuclear Entry and Infection

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.29.560083

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6 citations

Alexander J. Bryer, Jonathan Andino, Jiong Shi, Jun Hong, Cameron Torres +6 more

The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.08.566350

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0 citations

Harrison Bracey, Danny T. Nguyen, Rishav Dasgupta, Alondra Vázquez Rivera, Nicolas Sluis‐Cremer +3 more

Elasticity of the HIV-1 core facilitates nuclear entry and infection

PLoS Pathogens(2024)10.1371/journal.ppat.1012537

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37 citations

Alexander J. Bryer, Jonathan R. Andino-Moncada, Jiong Shi, Jun Hong, Cameron Torres +6 more

The HIV-1 capsid serves as a nanoscale reaction vessel for reverse transcription

PLoS Pathogens(2024)10.1371/journal.ppat.1011810

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11 citations

Harrison Bracey, Jun Hong, Danny T. Nguyen, Rishav Dasgupta, Alondra Vázquez Rivera +4 more

Cyclophilin A facilitates HIV-1 integration

Journal of Virology(2024)10.1128/jvi.00947-24

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9 citations

Richa Dwivedi, Rajasree Chakraborty, Prem Prakash, Kyusik Kim, Jiong Shi +7 more

Essential functions of inositol hexakisphosphate (IP6) in murine leukemia virus replication

mBio(2024)10.1128/mbio.01158-24

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3 citations

Kin Kui Lai, Harrison Bracey, Siddhartha A.K. Datta, Demetria Harvin, Gregory A. Sowd +3 more

Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.09.617473

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5 citations

Megan E. Meuser, Juan S. Rey, Hamed Meshkin, Rachel Yang, Swapnil C. Devarkar +6 more

Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.27.581940

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0 citations

Kin Kui Lai, Harrison Bracey, Siddhartha A.K. Datta, Demetria Harvin, Gregory A. Sowd +3 more

Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat

Journal of the American Chemical Society(2025)10.1021/jacs.5c13735

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6 citations

Megan E. Meuser, Juan S. Rey, Hamed Meshkin, Rachel Yang, Swapnil C. Devarkar +6 more

CPSF6 promotes HIV-1 preintegration complex function

Journal of Virology(2025)10.1128/jvi.00490-25

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4 citations

Sooin Jang, Rajasree Chakraborty, Rajalingam Radhakrishnan, Bjarki Arnarson, Prem Prakash +11 more

The host protein cyclophilin A inhibits HIV-1 nuclear entry by decreasing capsid elasticity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.03.673798

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2 citations

Akshay Deshpande, Yatish Thakare, Lora Simonovsky, AidanDarian W Douglas, Conall Mc Guinness +10 more

CPSF6 Promotes HIV-1 Preintegration Complex Function

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.28.635394

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0 citations

Sooin Jang, Rajasree Chakraborty, Rajalingam Radhakrishnan, Bjarki Arnarson, Prem Prakash +11 more