Tracy M. Handel

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS”.

A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS

Nature(2024)10.1038/s41586-024-08043-2

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1.1DataRank · unranked

34 citations

Menglan Xiang, Yuhan Bi, Serena Tan, Kevin Brulois, Aiman Ayesha +16 more

Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors

Journal of Leukocyte Biology(2020)10.1002/jlb.2ma0320-383rr

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0.477DataRank · unranked

23 citations

Guillaume Bernadat, Pasquale Cutolo, Carmen Gallego, Martin Gustavsson, Erika Cecon +6 more

Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.15.567150

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0.292DataRank · unranked

6 citations

Grant M. Wadman, Penglie Zhang, Andrew J. Tebben, Percy H. Carter, Siyi Gu +6 more

Functional anatomy of the full length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.21.913772

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0DataRank · unranked

5 citations

Tony Ngo, Irina Kufareva, Tracy M. Handel, Bryan S. Stephens

Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.0c01137

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0DataRank · unranked

31 citations

Kirti Kandhwal Chahal, Tereza Šimková, Cas van der Horst, Yi Zheng, Asuka Inoue +9 more

Anticancer opportunities at every stage of chemokine function

Trends in Pharmacological Sciences(2021)10.1016/j.tips.2021.08.001

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0DataRank · unranked

31 citations

Martijn P. Bemelmans, Tracy M. Handel, Karin E. de Visser, Laura H. Heitman, Natalia V. Ortiz Zacarı́as

Structures of atypical chemokine receptor 3 reveal the basis for its promiscuity and signaling bias

Science Advances(2022)10.1126/sciadv.abn8063

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0DataRank · unranked

86 citations

Christopher T. Schafer, Martin Gustavsson, S.A. Eberle, Pawel K. Dominik, Dawid Deneka +6 more

Seven structures of atypical chemokine receptor 3 reveal the molecular bases for its promiscuity and signaling bias

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r3991

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0DataRank · unranked

1 citations

Christopher T. Schafer, Martin Gustavsson, S.A. Eberle, Pawel K. Dominik, Dawid Deneka +6 more

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate widespread immune cell recruitment independent of chemokine receptors

Cell Reports(2023)10.1016/j.celrep.2022.111930

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0DataRank · unranked

77 citations

Richard Karlsson, Abigail R. E. Roberts, Amanda J. L. Ridley, Nabina Pun, Bakhtbilland Khan +19 more

The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms

Science Signaling(2023)10.1126/scisignal.abo4314

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0DataRank · unranked

39 citations

Irina Kufareva, Catherina L. Salanga, Tracy M. Handel, Thomas M. Shroka

Atypical Chemokine Receptor 3 “Senses” CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation

Molecular Pharmacology(2023)10.1124/molpharm.123.000710

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0DataRank · unranked

38 citations

Qiuyan Chen, J.J.G. Tesmer, Tracy M. Handel, Christopher T. Schafer

On-bead purification and nanodisc reconstitution of human chemokine receptor complexes for structural and biophysical studies

STAR Protocols(2023)10.1016/j.xpro.2023.102460

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0DataRank · unranked

2 citations

Mian Huang, Tracy M. Handel, Siyi Gu

Ligand-Dependent Mechanisms of CC Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.01.565224

N/A

0DataRank · unranked

10 citations

Svetlana Maurya, Alexis Lona, Leire Borrega‐Román, Catherina L. Salanga, David J. Gonzalez +3 more

Atypical Chemokine Receptor 3 ‘Senses’ CXC Chemokine Receptor 4 Activation Through GPCR Kinase Phosphorylation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.25.530029

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0DataRank · unranked

2 citations

Qiuyan Chen, J.J.G. Tesmer, Tracy M. Handel, Christopher T. Schafer

Distinct activation mechanisms of CXCR4 and ACKR3 revealed by single-molecule analysis of their conformational landscapes

eLife(2024)10.7554/elife.100098

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0DataRank · unranked

7 citations

Raymond F. Pauszek, Martin Gustavsson, Tracy M. Handel, David P. Millar, Christopher T. Schafer

Essential strategies for the detection of constitutive and ligand-dependent Gi-directed activity of 7TM receptors using bioluminescence resonance energy transfer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.12.04.626681

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0DataRank · unranked

0 citations

Kirti Kandhwal Chahal, JULIE A. RESNICK, Ekta Khare, Suchismita Roy, Tracy M. Handel +2 more

Effect of phosphorylation barcodes on arrestin binding to a chemokine receptor

Nature(2025)10.1038/s41586-025-09024-9

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0DataRank · unranked

28 citations

Christopher T. Schafer, Somnath Mukherjee, Kai Wang, Martin Gustavsson, James R. Fuller +11 more

Noncanonical roles of chemokine regions in CCR9 activation revealed by structural modeling and mutational mapping

Nature Communications(2025)10.1038/s41467-025-62321-9

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0DataRank · unranked

8 citations

John R.D. Dawson, Nicolas Calo, Marianne Paolini‐Bertrand, Kalyana Bharati Akondi, Gavin Tan +4 more

Traffic control: Mechanisms of ligand-specific internalization and intracellular distribution of CCR5

Molecular Pharmacology(2025)10.1016/j.molpha.2025.100020

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0DataRank · unranked

3 citations

Svetlana Maurya, Alexis Lona, Leire Borrega‐Román, Catherina L. Salanga, David J. Gonzalez +3 more

Rules of engagement: Determinants of chemokine receptor activation and selectivity by CCL27 and CCL28

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110736

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0DataRank · unranked

1 citations

Aura F. Celniker, Rezvan Chitsazi, Douglas P. Dyer, Ariane Jansma, Irina Kufareva +3 more

Chemokine-chemokine receptor networks in conventional type I dendritic cells: an opportunity to prime and boost anticancer immunity

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103725

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0DataRank · unranked

1 citations

Charlotte Shinn, Shiruyeh Schokrpur, Juliana Idoyaga, Tracy M. Handel, J. Silvio Gutkind +1 more

Activating the CXCR3/CXCL10 pathway overrides tumor immune suppression by enhancing immune trafficking and effector cell priming in head and neck squamous cell carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650529

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0DataRank · unranked

7 citations

Robert Saddawi‐Konefka, Catherina L. Salanga, Shiruyeh Schokrpur, J. Silvio Gutkind, Tracy M. Handel +1 more

Author response: Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes

(2025)10.7554/elife.100098.2.sa0

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0DataRank · unranked

0 citations

Raymond F. Pauszek, Martin Gustavsson, Tracy M. Handel, David P. Millar, Christopher T. Schafer

Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis

Science Signaling(2020)10.1126/scisignal.aay5024

N/A

0DataRank · unranked

49 citations

Tony Ngo, Irina Kufareva, Tracy M. Handel, Bryan S. Stephens

871 Immune architecture by design: chemokines as tools to sculpt the immune composition of solid tumors

Regular and Young Investigator Award Abstracts(2025)10.1136/jitc-2025-sitc2025.0871

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0DataRank · unranked

0 citations

Robert Saddawi‐Konefka, Shiruyeh Schokrpur, Catherina L. Salanga, J. Silvio Gutkind, Tracy M. Handel +1 more

Perspectives on the Biological Role of Chemokine:Glycosaminoglycan Interactions

Journal of Histochemistry & Cytochemistry(2020)10.1369/0022155420977971

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0DataRank · unranked

30 citations

Douglas P. Dyer, Tracy M. Handel

Crosslinking-guided geometry of a complete CXC receptor-chemokine complex and the basis of chemokine subfamily selectivity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.01.10.900951

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0DataRank · unranked

6 citations

Bryan S. Stephens, Martin Gustavsson, Lauren G. Holden, Ruben Abagyan, Tracy M. Handel +2 more