Hope Northrup

Also affiliated with The University of Texas MD Anderson Cancer Center, Cardiovascular Institute of the South, Behavioral Pharma (United States), The University of Texas Health Science Center, The University of Texas Health Science Center at Houston

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

2.7Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex

PLoS ONE(2020)10.1371/journal.pone.0232376

Top 13%

1.6DataRank

Top 13%35 citations

Edward Yang, Paola Calvachi, Marta Amengual‐Gual, Joyce Y. Wu, Darcy A. Krueger +7 more

Papers

Driven by 31 papers — median percentile 77. Top paper: “Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex”.

Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex

PLoS ONE(2020)10.1371/journal.pone.0232376

Top 13%

1.6DataRank

Top 13%35 citations

Edward Yang, Paola Calvachi, Marta Amengual‐Gual, Joyce Y. Wu, Darcy A. Krueger +7 more

Profile of Autism Spectrum Disorder in Tuberous Sclerosis Complex: Results from a Longitudinal, Prospective, Multisite Study

Annals of Neurology(2021)10.1002/ana.26249

Top 23%

0.895DataRank

Top 23%38 citations

Marian E. Williams, Deborah A. Pearson, R. David Kissinger, Paul S. Horn, Donna S. Murray +9 more

The youngest pair of siblings with Mucopolysaccharidosis type IVA to receive enzyme replacement therapy to date: A case report

American Journal of Medical Genetics Part A(2021)10.1002/ajmg.a.62469

N/A

0.738DataRank · unranked

12 citations

David F. Rodriguez‐Buritica, Heather Saavedra, Kathryn A. Gunther, Paul R. Hillman, Duraisamy Balaguru +2 more

Novel pathogenic variants and quantitative phenotypic analyses of Robinow syndrome: WNT signaling perturbation and phenotypic variability

Human Genetics and Genomics Advances(2021)10.1016/j.xhgg.2021.100074

N/A

0.557DataRank · unranked

40 citations

Angad Jolly, Brian J. Shayota, Juliana F. Mazzeu, Haowei Du, Moez Dawood +45 more

Identification of novel candidate risk genes for myelomeningocele within the glucose homeostasis/oxidative stress and folate/one‐carbon metabolism networks

Molecular Genetics & Genomic Medicine(2020)10.1002/mgg3.1495

N/A

0.511DataRank · unranked

13 citations

Craig Baker, Luke Hebert, Michael R. Brown, James E. Hixson, Allison E. Ashley‐Koch +4 more

Bone Health in Adults with Phenylketonuria: A Cross-Sectional Study

Journal of Inborn Errors of Metabolism and Screening(2021)10.1590/2326-4594-jiems-2021-0017

Top 65%

0.196DataRank

Top 65%2 citations

Hope Northrup, David F. Rodriguez‐Buritica, S. Shahrukh Hashmi, Heather Saavedra, Anjali Aggarwal

Tuber Locations Associated with Infantile Spasms Map to a Common Brain Network

Annals of Neurology(2021)10.1002/ana.26015

N/A

0DataRank · unranked

60 citations

Brechtje P. F. Mulder, Anna K. Prohl, Louis Soussand, Peter E. Davis, Mallory R. Kroeck +12 more

The current state of prenatal detection of genetic conditions in congenital heart defects

Translational Pediatrics(2021)10.21037/tp-20-315

N/A

0DataRank · unranked

22 citations

Hope Northrup, Tina O. Findley

Human myelomeningocele risk and ultra-rare deleterious variants in genes associated with cilium, WNT-signaling, ECM, cytoskeleton and cell migration

Scientific Reports(2021)10.1038/s41598-021-83058-7

N/A

0DataRank · unranked

21 citations

Luke Hebert, Paul R. Hillman, Craig Baker, Michael R. Brown, D.-K. Kim +9 more

Discovering a new part of the phenotypic spectrum of Coffin-Siris syndrome in a fetal cohort

Genetics in Medicine(2022)10.1016/j.gim.2022.04.010

N/A

0DataRank · unranked

21 citations

Marieke Joosten, Caroline Alby, Tania Attié‐Bitach, Kelly L. Gilmore, Christèle Dubourg +50 more

Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy

medRxiv(2022)10.1101/2022.08.23.22278845

N/A

0DataRank · unranked

0 citations

Vincent Francis, Sheng‐Jia Lin, Fares Kharfallah, Vladimir S. Fonov, Maxime Levesque +80 more

SRSF1 haploinsufficiency is responsible for a syndromic developmental disorder associated with intellectual disability

The American Journal of Human Genetics(2023)10.1016/j.ajhg.2023.03.016

N/A

0DataRank · unranked

25 citations

Aurore Garde, Thierry Gautier, Kathleen Rooney, Yannis Duffourd, Pontus LeBlanc +59 more

Epilepsy Severity Is Associated With Head Circumference and Growth Rate in Infants With Tuberous Sclerosis Complex

Pediatric Neurology(2023)10.1016/j.pediatrneurol.2023.03.015

N/A

0DataRank · unranked

5 citations

Peter E. Davis, Bo Zhang, Jurriaan M. Peters, Rajna Filip‐Dhima, Simon K. Warfield +8 more

Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results

Annals of the Child Neurology Society(2024)10.1002/cns3.20070

N/A

0DataRank · unranked

17 citations

David M. Ritter, David Neal Franz, Molly S. Griffith, Kristn Currans, Bridget Kent +15 more

ARMC5 controls the degradation of most Pol II subunits, and ARMC5 mutation increases neural tube defect risks in mice and humans

Genome biology(2024)10.1186/s13059-023-03147-w

N/A

0DataRank · unranked

16 citations

Linjiang Lao, Kit Sing Au, Hope Northrup, Xiao He, Diane Forget +9 more

Risk of meningomyelocele mediated by the common 22q11.2 deletion

Science(2024)10.1126/science.adl1624

N/A

0DataRank · unranked

21 citations

Sangmoon Lee, Kit Sing Au, T. Blaine Crowley, Valeria Capra, Meade Haller +74 more

Accumulated seizure burden predicts neurodevelopmental outcome at 36 months of age in patients with tuberous sclerosis complex

Epilepsia(2024)10.1111/epi.18172

N/A

0DataRank · unranked

10 citations

Samuel Alperin, Jamie K. Capal, Alexander L. Cohen, Jurriaan M. Peters, E. Martina Bebin +5 more

Loss of symmetric cell division of apical neural progenitors drives DENND5A-related developmental and epileptic encephalopathy

Nature Communications(2024)10.1038/s41467-024-51310-z

N/A

0DataRank · unranked

5 citations

Vincent Francis, Sheng‐Jia Lin, Fares Kharfallah, Vladimir S. Fonov, Maxime Lévesque +80 more

Abnormality of Early White Matter Development in Tuberous Sclerosis Complex and Autism Spectrum Disorder: Longitudinal Analysis of Diffusion Tensor Imaging Measures

Journal of Child Neurology(2024)10.1177/08830738241248685

N/A

0DataRank · unranked

6 citations

Fanghan Yang, Anna K. Prohl, Peter E. Davis, Jamie K. Capal, Rajna Filip‐Dhima +9 more

Common epilepsy variants from the general population are not associated with epilepsy among individuals with tuberous sclerosis complex

American Journal of Medical Genetics Part A(2024)10.1002/ajmg.a.63569

N/A

0DataRank · unranked

1 citations

Philip J. Lupo, Erik A. Ehli, Mustafa Sahin, Darcy A. Krueger, Joyce Y. Wu +6 more

Accumulated seizure burden predicts neurodevelopmental outcome at 36 months of age in patients with tuberous sclerosis complex

UNC Libraries(2024)10.17615/6x4t-0p12

N/A

0DataRank · unranked

2 citations

Darcy A. Krueger, Samuel Alperin, Jurriaan M. Peters, S. Katie Z. Ihnen, Jamie K. Capal +5 more

Preventative treatment of tuberous sclerosis complex with sirolimus: Phase I safety and efficacy results

UNC Libraries(2024)10.17615/f64k-h824

N/A

0DataRank · unranked

0 citations

David Neal Franz, Kenneth D.R. Setchell, Kristn Currans, Bridget Kent, E. Martina Bebin +15 more

The contribution of de novo coding mutations to meningomyelocele

Nature(2025)10.1038/s41586-025-08676-x

N/A

0DataRank · unranked

13 citations

Ashna Nisal, Isaac Tang, Chanjae Lee, Ishani Jhamb, Cassidy Wallace +74 more

Developmental Trajectories of Adaptive Functioning and Behavior Problems in Children With Co-Occurring Tuberous Sclerosis Complex and Autism Spectrum Disorder, With and Without Seizures

Pediatric Neurology(2025)10.1016/j.pediatrneurol.2025.07.008

N/A

0DataRank · unranked

5 citations

Melissa A. Richard, John P. Woodhouse, S. Katie Z. Ihnen, Jamie K. Capal, Hope Northrup +6 more

Which Score for What? Operationalizing Standardized Cognitive Test Performance for the Assessment of Change

American Journal on Intellectual and Developmental Disabilities(2025)10.1352/1944-7558-130.5.344

N/A

0DataRank · unranked

3 citations

Audrey Thurm, Tanvi Das, E. Martina Bebin, Jonathan A. Bernstein, Elizabeth Berry‐Kravis +14 more

Focal Adhesion Kinase Variants May Contribute to Risk of Human Myelomeningocele

medRxiv(2025)10.1101/2025.06.12.25329493

N/A

0DataRank · unranked

0 citations

C. Ravindranath Kamath, Sara Mansoorshahi, Myra Kurjee, Parkerson Laville, Ashabari Sprenger +5 more

Snx3 is important for mammalian neural tube closure via its role in canonical and non-canonical WNT signaling

Development(2020)10.1242/dev.192518

N/A

0DataRank · unranked

15 citations

Stephen A. Murray, Hope Northrup, Kit Sing Au, Lee Niswander, Heather M. Brown

Burden of rare deleterious variants in WNT signaling genes among 511 myelomeningocele patients

PLoS ONE(2020)10.1371/journal.pone.0239083

N/A

0DataRank · unranked

14 citations

Paul R. Hillman, Craig Baker, Michael R. Brown, Allison E. Ashley‐Koch, James E. Hixson +4 more

Pilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex

Pediatric Neurology(2020)10.1016/j.pediatrneurol.2020.04.002

N/A

0DataRank · unranked

45 citations

Jurriaan M. Peters, Tarrant McPherson, Darcy A. Krueger, Mustafa Sahin, Joyce Y. Wu +26 more

Epilepsy Risk Prediction Model for Patients With Tuberous Sclerosis Complex

Pediatric Neurology(2020)10.1016/j.pediatrneurol.2020.07.015

N/A

0DataRank · unranked

23 citations

Melissa A. Richard, Philip J. Lupo, Mustafa Şahin, Darcy A. Krueger, Joyce Y. Wu +21 more

Burden of Rare Deleterious Variants in WNT Signaling Genes Among 511 Myelomeningocele Patients

Digital Commons-TMC (Texas Medical Center)(2020)10.22541/au.158983195.57483136

N/A

0DataRank · unranked

1 citations

Paul R. Hillman, Craig Baker, Michael R. Brown, Allison E. Ashley‐Koch, James E. Hixson +4 more

Hope Northrup

Indexed papers

Top data-sharing exemplar

Papers