Lei Yang

Environmental ScienceBiochemistry, Genetics and Molecular BiologyNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 19 papers. Top paper: “Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5”.

Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.9b02067

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0DataRank · unranked

59 citations

Jude Chenge, Jingheng Wang, Hazel M. Girvan, Lei Yang, Sergio C. Chai +6 more

Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Angewandte Chemie International Edition(2021)10.1002/anie.202108848

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0DataRank · unranked

159 citations

Anand Mayasundari, Fatemeh Keramatnia, Barbara Jonchère, Seung Wook Yang, Jamie Jarusiewicz +22 more

Design, Synthesis, and Biological Evaluation of Stable Colchicine-Binding Site Tubulin Inhibitors 6-Aryl-2-benzoyl-pyridines as Potential Anticancer Agents

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00715

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0DataRank · unranked

55 citations

Shanshan Deng, Najah Albadari, Mi‐Kyung Yun, Sicheng Zhang, Yong Li +8 more

X-ray Crystallography-Guided Design, Antitumor Efficacy, and QSAR Analysis of Metabolically Stable Cyclopenta-Pyrimidinyl Dihydroquinoxalinone as a Potent Tubulin Polymerization Inhibitor

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c01202

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0DataRank · unranked

31 citations

Foyez Mahmud, Shanshan Deng, Lingling Ma, Mi‐Kyung Yun, Sayo O. Fakayode +12 more

NUDT15 polymorphism influences the metabolism and therapeutic effects of acyclovir and ganciclovir

Nature Communications(2021)10.1038/s41467-021-24509-7

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0DataRank · unranked

24 citations

Takanori Mizuno, Daniel Rehling, Colton Smith, Brandi L. Clark, Xujie Zhao +14 more

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

Malaria Journal(2021)10.1186/s12936-021-03617-1

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0DataRank · unranked

23 citations

Fangyi Zhu, Jared T. Hammill, Gloria Holbrook, Lei Yang, Burgess B. Freeman +7 more

Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs

Angewandte Chemie(2021)10.1002/ange.202108848

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0DataRank · unranked

15 citations

Anand Mayasundari, Fatemeh Keramatnia, Barbara Jonchère, Seung Wook Yang, Jamie Jarusiewicz +22 more

Combination of Ribociclib with BET-Bromodomain and PI3K/mTOR Inhibitors for Medulloblastoma Treatment In Vitro and In Vivo

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0896

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0DataRank · unranked

29 citations

Justin Williams, Frédérique Zindy, Jingjing Liu, Sarah Robinson, Dana M. Farmer +10 more

The orally bioavailable GSPT1/2 degrader SJ6986 exhibits in vivo efficacy in acute lymphoblastic leukemia

Blood(2023)10.1182/blood.2022017813

N/A

0DataRank · unranked

37 citations

Fatemeh Keramatnia, Pankaj S. Ghate, Gisele Nishiguchi, Qingsong Gao, Ilaria Iacobucci +12 more

Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia

Cell Reports(2023)10.1016/j.celrep.2023.112804

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0DataRank · unranked

33 citations

Hiroki Yoshihara, Qingsong Gao, Chunxu Qu, Ilaria Iacobucci, Pankaj S. Ghate +16 more

Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2

Nature Communications(2024)10.1038/s41467-024-52966-3

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0DataRank · unranked

26 citations

Suresh Dharuman, Elizabeth C. Griffith, Sergio C. Chai, Jarrid Ronnebaum, Moeko T. King +17 more

Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy

Molecular Cancer(2024)10.1186/s12943-024-02027-6

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0DataRank · unranked

18 citations

Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Brandon Bianski +29 more

Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2314101120

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0DataRank · unranked

12 citations

Martin N. Cheramie, Dinesh M. Fernando, Petra Selchow, Christopher J. Meyer, Samanthi L. Waidyarachchi +20 more

Development of Brain Penetrant Pyridazine Pantothenate Kinase Activators

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01211

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0DataRank · unranked

5 citations

Chitra Subramanian, Mi‐Kyung Yun, Anne Edwards, Lalit Sharma, Lei Yang +7 more

Development of tetracycline analogues with increased aqueous stability for the treatment of mycobacterial infections

Tuberculosis(2024)10.1016/j.tube.2024.102592

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0DataRank · unranked

4 citations

Gregory A. Phelps, C DUNN, Patricia A. Murphy, Laura A. Wilt, Victoria Loudon +8 more

Unbiased mapping of cereblon neosubstrate landscape by high-throughput proteomics

Nature Communications(2025)10.1038/s41467-025-62829-0

N/A

0DataRank · unranked

25 citations

Gisele Nishiguchi, Qiong Wu, Bjoern Schwalb, Bachuki Shashikadze, Kevin McGowan +16 more

Decoding the selective chemical modulation of CYP3A4

Nature Communications(2025)10.1038/s41467-025-58749-8

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0DataRank · unranked

6 citations

Stanley Nithianantham, Sergio C. Chai, Kwan‐Young Jung, Lei Yang, Han Wee Ong +5 more

LCK-targeting molecular glues overcome resistance to inhibitor-based therapy in T-cell acute lymphoblastic leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.03.663042

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0DataRank · unranked

1 citations

Gisele Nishiguchi, Satoshi Yoshimura, Marisa Actis, Justin T. Seffernick, Jamie Jarusiewicz +9 more

Hidden-driver inference reveals synergistic brain-penetrant therapies for medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.20.689490

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0DataRank · unranked

0 citations

Yang Xu, Mingrui Zhu, Xinran Dong, Honglei Zhou, Brandon Bianski +14 more