Hans Clevers

Royal Netherlands Academy of Arts and Sciences

Also affiliated with Oncode Institute, Hubrecht Institute for Developmental Biology and Stem Cell Research, Princess Máxima Center

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

55.6Author DataRank

Indexed papers

11in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 11 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Cell(2015)10.1016/j.cell.2015.03.053

Top 1%

12.6DataRank

Top 1%2459 citations

Hayley E. Francies, Joshua M. Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk +32 more

Papers

Driven by 46 papers — median percentile 98. Top paper: “Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients”.

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

Cell(2015)10.1016/j.cell.2015.03.053

Top 1%

12.6DataRank

Top 1%2459 citations

Hayley E. Francies, Joshua M. Francis, Gergana Bounova, Francesco Iorio, Apollo Pronk +32 more

A global reference for human genetic variation

Nature(2015)10.1038/nature15393

Top 1%

10.6DataRank

Top 1%20166 citations

Gonçalo R. Abecasis, Richard M. Durbin, Panagiotis Deloukas, Aravinda Chakravarti, Peter Donnelly +516 more

An integrated map of structural variation in 2,504 human genomes

Nature(2015)10.1038/nature15394

Top 2%

9.1DataRank

Top 2%2686 citations

Tobias Rausch, Marianne K. DeGorter, Robert E. Handsaker, Alexej Abyzov, Joanna M. M. Howson +75 more

A promoter-level mammalian expression atlas

Nature(2014)10.1038/nature13182

Top 2%

8.9DataRank

Top 2%2192 citations

Alistair R. R. Forrest, J. Kenneth Baillie, Michiel de Hoon, Timo Lassmann, Ivan V. Kulakovskiy +262 more

Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel

Nature Communications(2014)10.1038/ncomms4934

Top 2%

8.3DataRank

Top 2%460 citations

Jonathan Marchini, Peter Donnelly, Gerton Lunter, Jonathan L. Marchini, Simon Myers +364 more

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

Genome Research(2017)10.1101/gr.213611.116

Top 2%

8.0DataRank

Top 2%1305 citations

Thibaut Hourlier, Lon Phan, Hsiu-Chuan Chen, Paul A. Kitts, Terence D. Murphy +37 more

Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly

bioRxiv (Cold Spring Harbor Laboratory)(2016)10.1101/072116

Top 6%

3.8DataRank

Top 6%118 citations

Tina A. Graves-Lindsay, Thibaut Hourlier, Lon Phan, Hsiu-Chuan Chen, Paul A. Kitts +34 more

The Organoid Cell Atlas

Nature Biotechnology(2020)10.1038/s41587-020-00762-x

Top 6%

3.8DataRank

Top 6%172 citations

Michael Boutros, J. Gray Camp, Hans Clevers, Juergen A. Knoblich, Prisca Liberali +7 more

The Human Cell Atlas White Paper

arXiv (Cornell University)(2018)10.17863/cam.40032

Top 10%

2.2DataRank

Top 10%41 citations

Sarah A. Teichmann, Orit Rozenblatt‐Rosen, Michael J. T. Stubbington, Kristin G. Ardlie, Ido Amit +76 more

Erratum: Genome analysis of the platypus reveals unique signatures of evolution

Nature(2008)10.1038/nature07253

N/A

1.6DataRank · unranked

35 citations

LaDeana W. Hillier, Jennifer A. Marshall Graves, Kerstin Lindblad‐Toh, Elaine A. Ostrander, Frank Grützner +115 more

Neurotoxic reactive astrocytes are induced by activated microglia

Nature(2017)10.1038/nature21029

N/A

1.3DataRank · unranked

7848 citations

Kevin A. Guttenplan, Laura E. Clarke, Frederick C. Bennett, Christopher J. Bohlen, Lucas Schirmer +19 more

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Nature(2009)10.1038/nature07935

N/A

1.3DataRank · unranked

7052 citations

Robert G. Vries, Hugo J Snippert, Marc van de Wetering, Nick Barker, Daniel E. Stange +8 more

Transcription Factor Achaete Scute-Like 2 Controls Intestinal Stem Cell Fate

Cell(2009)10.1016/j.cell.2009.01.031

N/A

0.987DataRank · unranked

719 citations

Marielle E. van Gijn, Pantelis Hatzis, Pekka Kujala, Andrea Haegebarth, Daniel E. Stange +12 more

Evidence generation and reproducibility in cell and gene therapy research: A call to action

Molecular Therapy - Methods & Clinical Development(2021)10.1016/j.omtm.2021.06.012

N/A

0.934DataRank · unranked

24 citations

Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman +33 more

Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation

Nature Neuroscience(2013)10.1038/nn.3371

N/A

0.905DataRank · unranked

416 citations

Martin Krüger, Felix Buggenthin, Julia Schwausch, Jovica Ninkovic, Hans Clevers +9 more

KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

eLife(2021)10.7554/elife.66608

N/A

0.902DataRank · unranked

22 citations

Danielle E. Frodyma, Siddesh Southekal, Robert A. Svoboda, Adrian R. Black, Chittibabu Guda +6 more

SOX9 Is Required for the Differentiation of Paneth Cells in the Intestinal Epithelium

Gastroenterology(2007)10.1053/j.gastro.2007.05.020

N/A

0.872DataRank · unranked

334 citations

Maaike van den Born, Johan H. van Es, Stanley R. Hamilton, Henry P. Adams, Jiexin Zhang +4 more

LifeTime and improving European healthcare through cell-based interceptive medicine

Nature(2020)10.1038/s41586-020-2715-9

N/A

0.747DataRank · unranked

144 citations

Geneviève Almouzni, Stanislaw A. Gorski, Stein Aerts, Ido Amit, Michela G. Bertero +178 more

Author response: The Human Cell Atlas

(2017)10.7554/elife.27041.011

Top 29%

0.700DataRank

Top 29%14 citations

Sarah A. Teichmann, Matthew E. Hurles, Ido Amit, Kerstin Lindblad‐Toh, Bernd Bodenmiller +60 more

The Organoid Cell Atlas: A Rosetta Stone for Biomedical Discovery and Regenerative Therapy

Zenodo (CERN European Organization for Nuclear Research)(2020)10.5281/zenodo.4001718

Top 52%

0.331DataRank

Top 52%3 citations

Michael Boutros, J. Gray Camp, Hans Clevers, Juergen A. Knoblich, Prisca Liberali +5 more

PGE 2 alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2220613120

N/A

0DataRank · unranked

17 citations

Avik Choudhuri, Meera Prasad, Brejnev Muhire, Eva M. Fast, Margot E. Manning +8 more

Report of the Assay Guidance Workshop on 3-Dimensional Tissue Models for Antiviral Drug Development

The Journal of Infectious Diseases(2023)10.1093/infdis/jiad334

N/A

0DataRank · unranked

7 citations

Stephanie L. Ford‐Scheimer, Rodolfo Alarcón, Anthony Atala, Jeffrey T. Borenstein, Kyle R. Brimacombe +23 more

Lgr5 + ductal cells of von Ebner’s glands are stem cells for turnover of posterior tongue taste buds

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.18.589316

N/A

0DataRank · unranked

2 citations

Anthony M. Downs, Alexandria J. Slepian, Johan H. van Es, Hans Clevers, Dennis M. Defoe +1 more

A Collection of Patient-Derived Intestinal Organoid Lines Reveals Epithelial Phenotypes Associated with Genetic Drivers of Pediatric Inflammatory Bowel Disease

Inflammatory Bowel Diseases(2025)10.1093/ibd/izaf296

N/A

0DataRank · unranked

3 citations

Carmen Argmann, Maaike Hillegonda de Vries, Johan H. van Es, Lauren V. Collen, Daniel Kotlarz +10 more

Human colon stem cells are the predominant epithelial responders to bacterial antigens

Frontiers in Immunology(2025)10.3389/fimmu.2025.1677943

N/A

0DataRank · unranked

1 citations

Claartje Meddens, Hemme Hijma, Anne‐Claire Berrens, Suze A. Jansen, Berend A. P. Kooiman +6 more

Mapping the complete influenza A virus infection cycle through single vRNP imaging

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.20.633851

N/A

0DataRank · unranked

3 citations

Janin Schokolowski, Micha Müller, Matthijs J.D. Baars, Antonella F. M. Dost, Theo M. Bestebroer +5 more

Chromatin Remodeling in Patient‐Derived Colorectal Cancer Models

Advanced Science(2024)10.1002/advs.202303379

N/A

0DataRank · unranked

14 citations

Ergang Wang, John B. Mantyh, Gabrielle Rupprecht, Marcos Negrete, Golshid Sanati +24 more

Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo

Cell stem cell(2020)10.1016/j.stem.2020.07.020

N/A

0DataRank · unranked

153 citations

Andrew Ha, Wim de Lau, Kanako Yuki, António J. M. Santos, Changjiang You +28 more

Fasting-mimicking diet and hormone therapy induce breast cancer regression

Nature(2020)10.1038/s41586-020-2502-7

N/A

0DataRank · unranked

362 citations

V. Spagnolo, Claudio Vernieri, Francesca Valdemarin, Pamela Becherini, Min Wei +29 more

A Human Organoid Model of Aggressive Hepatoblastoma for Disease Modeling and Drug Testing

Cancers(2020)10.3390/cancers12092668

N/A

0DataRank · unranked

59 citations

William J. Hammond, Nicole J.C. Narayan, David Requena, Helmuth Gehart, Gadi Lalazar +4 more

Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.12.989277

N/A

0DataRank · unranked

2 citations

Mark E. Robinson, Gauri Deb, Xin Yang, Gang Xiao, Teresa Sadras +16 more

Serine Palmitoyltransferase Controls Stemness of Intestinal Progenitors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.03.409128

N/A

0DataRank · unranked

1 citations

Bhagirath Chaurasia, Vincent Kaddai, Joseph L. Wilkerson, J. Alan Maschek, James E. Cox +10 more

Targeted inhibition of Wnt signaling with a bacterial toxin fragment suppresses breast cancer tumor-initiating/chemo-resistant cells

Research Square(2020)10.21203/rs.3.rs-58989/v1

N/A

0DataRank · unranked

1 citations

Dongxi Xiang, Oded Kopper, Daniel J. Horan, Peng Chen, Roderick Bronson +17 more

Promises and challenges of organoid-guided precision medicine

Med(2021)10.1016/j.medj.2021.08.005

N/A

0DataRank · unranked

204 citations

Hans Clevers, Xiling Shen, Shree Bose

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

Genome biology(2021)10.1186/s13059-021-02413-z

N/A

0DataRank · unranked

70 citations

Martin Jaeger, Joep Beumer, Olivier B. Bakker, Raúl Aguirre‐Gamboa, Marije Oosting +28 more

The frontier of live tissue imaging across space and time

Cell stem cell(2021)10.1016/j.stem.2021.02.010

N/A

0DataRank · unranked

61 citations

Aliesha Garrett, Shree Bose, Stephanie J. Blocker, Anne C. Rios, Hans Clevers +2 more

Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma

Gastroenterology(2021)10.1053/j.gastro.2021.12.273

N/A

0DataRank · unranked

58 citations

Gita Dangol, Takashi Okumura, Jason Roszik, Kimal Rajapakshe, Megan J. Siemann +11 more

Patient-derived micro-organospheres enable clinical precision oncology

Cell stem cell(2022)10.1016/j.stem.2022.04.006

N/A

0DataRank · unranked

214 citations

Carolyn Hsu, Zhaohui Wang, Naveen Natesh, Rosemary Millen, Marcos Negrete +32 more

A path to translation: How 3D patient tumor avatars enable next generation precision oncology

Cancer Cell(2022)10.1016/j.ccell.2022.09.017

N/A

0DataRank · unranked

66 citations

Margarida Barroso, Milan G. Chheda, Hans Clevers, Élena Elez, Salma Kaochar +21 more

Rapid tissue prototyping with micro-organospheres

Stem Cell Reports(2022)10.1016/j.stemcr.2022.07.016

N/A

0DataRank · unranked

53 citations

Matteo Boretto, Rosemary Millen, Naveen Natesh, Elena S. Reckzeh, Carolyn Hsu +33 more

Human liver organoids for disease modeling of fibrolamellar carcinoma

Stem Cell Reports(2022)10.1016/j.stemcr.2022.06.003

N/A

0DataRank · unranked

23 citations

David Requena, Gadi Lalazar, Lavoisier Ramos‐Espiritu, Denise Ng, Solomon Levin +10 more

RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis

Stem Cell Reports(2022)10.1016/j.stemcr.2021.12.002

N/A

0DataRank · unranked

19 citations

Xiaoli Lin, Jumpei Yamashita, Ranhui Xi, Minliang Zhou, Yali V. Zhang +7 more

Chromatin Remodeling in Patient-Derived Colorectal Cancer Models

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.24.501300

N/A

0DataRank · unranked

1 citations

Ergang Wang, Gabrielle Rupprecht, John B. Mantyh, Marcos Negrete, Golshid Sanati +20 more

A tissue-intrinsic IL-33/EGF circuit promotes epithelial regeneration after intestinal injury

Nature Communications(2023)10.1038/s41467-023-40993-5

N/A

0DataRank · unranked

50 citations

Ya–Yuan Fu, Paola Vinci, Viktor Arnhold, Winston Chang, Suze A. Jansen +13 more

Ceramides Increase Fatty Acid Utilization in Intestinal Progenitors to Enhance Stemness and Increase Tumor Risk

Gastroenterology(2023)10.1053/j.gastro.2023.07.017

N/A

0DataRank · unranked

38 citations

Bhagirath Chaurasia, Mohammed Mahidur Rahman, Vincent Kaddai, J. Alan Maschek, Jordan A. Berg +22 more

Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities

Oncogene(2023)10.1038/s41388-023-02681-y

N/A

0DataRank · unranked

36 citations

Justin Williams, Carla Ríos Arceo, Femke Ringnalda, Kimberly Mercer, Juliane L. Buhl +13 more

Hans Clevers

Indexed papers

Top data-sharing exemplar

Papers