Yves Pommier

Also affiliated with National Cancer Institute, Center for Cancer Research

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

10.9Author DataRank

Indexed papers

10in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 10 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics

Nucleic Acids Research(2020)10.1093/nar/gkaa968

Top 5%

4.8DataRank

Top 5%229 citations

Fathi Elloumi, Sudhir Varma, Yanghsin Wang, Vinodh N. Rajapakse, Mirit I. Aladjem +5 more

Papers

Driven by 140 papers — median percentile 20. Top paper: “Genomic and evolutionary classification of lung cancer in never smokers”.

Genomic and evolutionary classification of lung cancer in never smokers

Nature Genetics(2021)10.1038/s41588-021-00920-0

N/A

5.4DataRank · unranked

248 citations

Philippe Joubert, Naser Ansari‐Pour, Zhao Wei, Phuc H. Hoang, Rachel Lokanga +56 more

CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics

Nucleic Acids Research(2020)10.1093/nar/gkaa968

Top 5%

4.8DataRank

Top 5%229 citations

Fathi Elloumi, Sudhir Varma, Yanghsin Wang, Vinodh N. Rajapakse, Mirit I. Aladjem +5 more

SCLC-CellMiner: A Resource for Small Cell Lung Cancer Cell Line Genomics and Pharmacology Based on Genomic Signatures

Cell Reports(2020)10.1016/j.celrep.2020.108296

Top 5%

4.2DataRank

Top 5%170 citations

Lőrinc Sándor Pongor, Fathi Elloumi, Luc Girard, Kenneth E. Huffman, Nitin Roper +14 more

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-20-1026

N/A

2.9DataRank · unranked

111 citations

Ilya S. Senatorov, Astrid Zimmermann, Liton Kumar Saha, Yasuhisa Murai, Se Hyun Kim +8 more

Suppressing proteasome mediated processing of topoisomerase II DNA-protein complexes preserves genome integrity

eLife(2020)10.7554/elife.53447

N/A

1.4DataRank · unranked

44 citations

Wei Wu, Dali Zong, Yilun Sun, Nancy Wong, Sam John +6 more

Berzosertib Plus Topotecan vs Topotecan Alone in Patients With Relapsed Small Cell Lung Cancer

JAMA Oncology(2023)10.1001/jamaoncol.2023.4025

N/A

1.1DataRank · unranked

48 citations

Zhonglin Hao, Liza C. Villaruz, Jun Zhang, Jimmy Ruiz, W. Jeffrey Petty +33 more

ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer

EMBO Molecular Medicine(2023)10.15252/emmm.202217313

N/A

0.944DataRank · unranked

28 citations

Yang Zhang, Rajaâ El Meskini, Astrid Zimmermann, Haiqing Fu, Yasuhisa Murai +21 more

CellMinerCDB: NCATS Is a Web-Based Portal Integrating Public Cancer Cell Line Databases for Pharmacogenomic Explorations

Cancer Research(2023)10.1158/0008-5472.can-22-2996

Top 23%

0.862DataRank

Top 23%32 citations

Kelli M. Wilson, Fathi Elloumi, Katie R. Bradwell, Michele Ceribelli, Sudhir Varma +12 more

Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors

Cancer Chemotherapy and Pharmacology(2020)10.1007/s00280-020-04134-9

N/A

0.730DataRank · unranked

20 citations

Alwin D. R. Huitema, Thomas P. C. Dorlo, Cody J. Peer, Lisa M. Cordes, Linda Sciuto +6 more

Integrative epigenomic analyses of small cell lung cancer cells demonstrates the clinical translational relevance of gene body methylation

iScience(2022)10.1016/j.isci.2022.105338

Top 28%

0.704DataRank

Top 28%23 citations

Camille Tlemsani, Fathi Elloumi, Yasuhiro Arakawa, Ukhyun Jo, Jacob Gross +12 more

Autophagy-Dependent Sensitization of Triple-Negative Breast Cancer Models to Topoisomerase II Poisons by Inhibition of the Nucleosome Remodeling Factor

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0743

N/A

0.416DataRank · unranked

15 citations

Yilun Sun, Nga Dao, Hannah Ngo, Mallika Dammalapati, Ashish Vaidyanathan +13 more

Identification of DLK1, a Notch ligand, as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.09.617077

N/A

0.312DataRank · unranked

7 citations

Suresh Kumar, Yoo Sun Kim, Diana Grace Varghese, Arnulfo Mendoza, Rosa Nguyen +20 more

Phase 1 studies of the indenoisoquinolines LMP776 and LMP744 in patients with solid tumors and lymphomas

Cancer Chemotherapy and Pharmacology(2025)10.1007/s00280-025-04778-5

N/A

0.258DataRank · unranked

4 citations

Shivaani Kummar, Larry Rubinstein, Deborah Wilsker, Nancy Young Moore, Murielle Hogu +16 more

A Database Tool Integrating Genomic and Pharmacologic Data from Adrenocortical Carcinoma Cell Lines, PDX, and Patient Samples

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0100

Top 60%

0.248DataRank

Top 60%4 citations

Fathi Elloumi, Sudhir Varma, Prashant Khandagale, Ukhyun Jo, Suresh Kumar +18 more

Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

Nature Communications(2025)10.1038/s41467-025-60649-w

N/A

0.208DataRank · unranked

3 citations

Suresh Kumar, Yoo Sun Kim, Diana Grace Varghese, Arnulfo Mendoza, Rosa Nguyen +23 more

The Indenoisoquinoline LMP517: A Novel Antitumor Agent Targeting both TOP1 and TOP2

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-1064

N/A

0DataRank · unranked

15 citations

Yilun Sun, Shar-yin N. Huang, Amy James, Simone Difilippantonio, Yves Pommier +1 more

Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1920165117

N/A

0DataRank · unranked

32 citations

Mitsuo Wakasugi, Salma Akter, Rajendra Prasad, Samuel H. Wilson, Naoto Shimizu +11 more

Topoisomerase 3B (TOP3B) DNA and RNA Cleavage Complexes and Pathway to Repair TOP3B-linked RNA and DNA Breaks

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.22.002691

N/A

0DataRank · unranked

4 citations

Yilun Sun, Shar-yin N. Huang, Ukhyun Jo, Hongliang Zhang, Yuk‐Ching Tse‐Dinh +2 more

Randomized phase II trial of topotecan plus M6620 (VX-970) versus topotecan alone in patients with relapsed small-cell neuroendocrine cancers including small cell lung cancer.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.15_suppl.tps3653

N/A

0DataRank · unranked

0 citations

Rasa Vilimas, Samantha Nichols, Linda Sciuto, Santhana Webb, Seth M. Steinberg +3 more

BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks

Research Square(2020)10.21203/rs.2.20856/v2

N/A

0DataRank · unranked

0 citations

Jacob Gross, Roberto Vera Alvarez, Junko Murai, Sang‐Min Jang, Hongliang Zhang +10 more

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ

UNC Libraries(2020)10.17615/d0ab-qt43

N/A

0DataRank · unranked

0 citations

Toshiki Tsurimoto, Alan R. Lehmann, Yves Pommier, Jun Nakamura, Shunichi Takeda +11 more

Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity

UNC Libraries(2020)10.17615/yv41-9d10

N/A

0DataRank · unranked

0 citations

Shunichi Takeda, Anindya Dutta, Yoshiyuki Shibata, Yuh Hwa Wang, Yves Pommier +4 more

Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress

Cancer Cell(2021)10.1016/j.ccell.2021.02.014

N/A

0DataRank · unranked

178 citations

Nobuyuki Takahashi, Vinodh N. Rajapakse, Xiaohu Zhang, Yilun Sun, Michele Ceribelli +36 more

Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers

Journal of Thoracic Oncology(2021)10.1016/j.jtho.2021.08.763

N/A

0DataRank · unranked

153 citations

Patricia Fetsch, Anish Thomas, Yves Pommier, David S. Schrump, Markku Miettinen +2 more

Multiview confocal super-resolution microscopy

Nature(2021)10.1038/s41586-021-04110-0

N/A

0DataRank · unranked

123 citations

Xiaofei Han, Yijun Su, Melissa Glidewell, Jonathan S. Daniels, Jiamin Liu +22 more

PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation

Nature Communications(2021)10.1038/s41467-021-25252-9

N/A

0DataRank · unranked

75 citations

Jiji Chen, Shar-yin N. Huang, Yijun Su, Wenjie Wang, Keli Agama +5 more

Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair–targeted therapies

Science Translational Medicine(2021)10.1126/scitranslmed.abc7488

N/A

0DataRank · unranked

73 citations

Nobuyuki Takahashi, Lőrinc Sándor Pongor, Vinodh N. Rajapakse, Manoj Tyagi, Xinyu Wen +20 more

Discovery of 4-alkoxy-2-aryl-6,7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity

European Journal of Medicinal Chemistry(2021)10.1016/j.ejmech.2021.113261

N/A

0DataRank · unranked

57 citations

Wagdy M. Eldehna, Wenjie Wang, Keli Agama, Yves Pommier, Manabu Abe +1 more

Association of expression of epigenetic molecular factors with DNA methylation and sensitivity to chemotherapeutic agents in cancer cell lines

Clinical Epigenetics(2021)10.1186/s13148-021-01026-4

N/A

0DataRank · unranked

55 citations

Alida Palmisano, William C. Reinhold, Yves Pommier, Beverly A. Teicher, Julia Krushkal +1 more

SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243

Cancer Research(2021)10.1158/0008-5472.can-20-2694

N/A

0DataRank · unranked

55 citations

Ukhyun Jo, Junko Murai, Lisa M. Jenkins, Shar-yin N. Huang, Sirisha Chakka +6 more

Precision Oncology with Drugs Targeting the Replication Stress, ATR, and Schlafen 11

Cancers(2021)10.3390/cancers13184601

N/A

0DataRank · unranked

51 citations

Yasuhisa Murai, Naoko Takebe, Anish Thomas, Yves Pommier, Ukhyun Jo

2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights

Journal of Enzyme Inhibition and Medicinal Chemistry(2021)10.1080/14756366.2021.2015344

N/A

0DataRank · unranked

41 citations

Wagdy M. Eldehna, Amer Ali Abd El‐Hafeez, Warda R. Somaa, Amgad Albohy, Sara T. Al‐Rashood +6 more

Replication-dependent cytotoxicity and Spartan-mediated repair of trapped PARP1–DNA complexes

Nucleic Acids Research(2021)10.1093/nar/gkab777

N/A

0DataRank · unranked

38 citations

Yasuhisa Murai, Sourav Saha, Ukhyun Jo, Masataka Tsuda, Shunichi Takeda +2 more

The FDA-Approved Anthelmintic Pyrvinium Pamoate Inhibits Pancreatic Cancer Cells in Nutrient-Depleted Conditions by Targeting the Mitochondria

Molecular Cancer Therapeutics(2021)10.1158/1535-7163.mct-20-0652

N/A

0DataRank · unranked

36 citations

Grace A. McCarthy, Teena Nerwal, Avinoam Nevler, James B. DuHadaway, Matthew McCoy +23 more

Epigenetic suppression of SLFN11 in germinal center B-cells during B-cell development

PLoS ONE(2021)10.1371/journal.pone.0237554

N/A

0DataRank · unranked

33 citations

Momoko Nishikori, Tsuyoshi Takashima, Daiki Taniyama, Nobuyuki Onishi, Hiroshi Arima +9 more

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites

Chemical Science(2021)10.1039/d0sc05411a

N/A

0DataRank · unranked

33 citations

Evgeny Kiselev, G.T. Lountos, Wenjie Wang, Joseph E. Tropea, D. Needle +6 more

A polymer index-matched to water enables diverse applications in fluorescence microscopy

Lab on a Chip(2021)10.1039/d0lc01233e

N/A

0DataRank · unranked

32 citations

Yijun Su, Hamilton White, Kate M. O’Neill, Nicole Y. Morgan, Ryan Christensen +13 more

R-Loop–Mediated ssDNA Breaks Accumulate Following Short-Term Exposure to the HDAC Inhibitor Romidepsin

Molecular Cancer Research(2021)10.1158/1541-7786.mcr-20-0833

N/A

0DataRank · unranked

31 citations

Thomas Litman, Robert W. Robey, Andrés Aguilera, Arup R. Chakraborty, William C. Reinhold +8 more

Synthesis of Methoxy-, Methylenedioxy-, Hydroxy-, and Halo-Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1) Inhibitors and Their Biological Activity for Drug-Resistant Cancer

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00318

N/A

0DataRank · unranked

28 citations

Wen-Lin Tang, Yu Zhang, Hao Yang, Wenjie Wang, Keli Agama +3 more

Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes

Science Advances(2021)10.1126/sciadv.abe0384

N/A

0DataRank · unranked

26 citations

Stephanie A. Michaels, Brianna Mitchell, Nadim Majdalani, Arnaud Vanden Broeck, Andrés Canela +4 more

Functions of the CSB Protein at Topoisomerase 2 Inhibitors-Induced DNA Lesions

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.727836

N/A

0DataRank · unranked

3 citations

Sofiane Y. Mersaoui, Yilun Sun, Yves Pommier, Jean‐Yves Masson, Jenifer Saffi +1 more

Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

iScience(2021)10.1016/j.isci.2021.103173

N/A

0DataRank · unranked

18 citations

Ukhyun Jo, Junko Murai, Shinsaku Fukuda, Naoko Takebe, Yves Pommier +1 more

Design and synthesis of C-aryl angular luotonins via a one-pot aza-Nazarov–Friedlander sequence and their Topo-I inhibition studies along with C-aryl vasicinones and luotonins

Bioorganic & Medicinal Chemistry Letters(2021)10.1016/j.bmcl.2021.127998

N/A

0DataRank · unranked

13 citations

Vamshikrishna Reddy Sammeta, Zachary F. Murphy, James A. Golen, Keli Agama, Yves Pommier +2 more

The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors

Bioorganic Chemistry(2021)10.1016/j.bioorg.2021.104881

N/A

0DataRank · unranked

11 citations

Xiaoqing Zhu, Wenjie Wang, Yu Chen, Zhu Hu, Yu Zhang +6 more

Terpyridine platinum compounds induce telomere dysfunction and chromosome instability in cancer cells

Oncotarget(2021)10.18632/oncotarget.28020

N/A

0DataRank · unranked

5 citations

Hee-Sheung Lee, Mikhail Liskovykh, Marie‐Paule Teulade‐Fichou, Hiroshi Masumoto, William C. Earnshaw +4 more

NCI protocol 10250: A phase II study of temozolomide and olaparib for the treatment of advanced uterine leiomyosarcoma.

Journal of Clinical Oncology(2021)10.1200/jco.2021.39.15_suppl.11506

N/A

0DataRank · unranked

11 citations

Jacob B. Allred, Katherine Gano, Suzanne George, Steven Attia, Melissa Burgess +15 more

Functional characterization of two variants in the mitochondrial topoisomerase gene TOP1MT that impact regulation of the mitochondrial genome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.02.454711

N/A

0DataRank · unranked

0 citations

Jingti Deng, Andrew Symes, Marina Kerr, Hongliang Zhang, Shar-yin N. Huang +4 more

Terpyridine Platinum Compounds Induce Telomere Dysfunction and Chromosome Instability in Cancer Cells

Research Square(2021)10.21203/rs.3.rs-417658/v1

N/A

0DataRank · unranked

0 citations

Hee-Sheung Lee, Mikhail Liskovykh, Marie‐Paule Teulade‐Fichou, Hiroshi Masumoto, William C. Earnshaw +4 more

Human topoisomerases and their roles in genome stability and organization

Nature Reviews Molecular Cell Biology(2022)10.1038/s41580-022-00452-3

N/A

0DataRank · unranked

466 citations

André Nussenzweig, Shunichi Takeda, Caroline A. Austin, Yves Pommier

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin

Nature Cell Biology(2022)10.1038/s41556-021-00807-6

N/A

0DataRank · unranked

163 citations

Shudong Li, Yilun Sun, Andrew J. Wicks, Gwendoline Hoslett, Daniel Weekes +14 more

Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5

Cell Reports(2022)10.1016/j.celrep.2022.111067

N/A

0DataRank · unranked

72 citations

Xi Yang, Shar-yin N. Huang, Keli Agama, Simone A. Baechler, Yilun Sun +7 more

Structural, molecular, and functional insights into Schlafen proteins

Experimental & Molecular Medicine(2022)10.1038/s12276-022-00794-0

N/A

0DataRank · unranked

69 citations

Yves Pommier, Ukhyun Jo

TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-1000

N/A

0DataRank · unranked

55 citations

Yasuhisa Murai, Keli Agama, Yilun Sun, Liton Kumar Saha, Xi Yang +11 more

Replication Stress Defines Distinct Molecular Subtypes Across Cancers

Cancer Research Communications(2022)10.1158/2767-9764.crc-22-0168

N/A

0DataRank · unranked

52 citations

Se Hyun Kim, Christopher W. Schultz, Vinodh N. Rajapakse, Yang Zhang, Christophe E. Redon +7 more

Topoisomerase I poison-triggered immune gene activation is markedly reduced in human small-cell lung cancers by impairment of the cGAS/STING pathway

British Journal of Cancer(2022)10.1038/s41416-022-01894-4

N/A

0DataRank · unranked

49 citations

Andrea Arleo, Marco Russo, Maria Delcuratolo, Francesca D. Ciccarelli, Yves Pommier +2 more

Pediatric adrenocortical carcinoma

Frontiers in Endocrinology(2022)10.3389/fendo.2022.961650

N/A

0DataRank · unranked

44 citations

Diana Grace Varghese, John Glod, Karlyne M. Reilly, Brigitte C. Widemann, Yves Pommier +3 more

Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states

Nature Communications(2022)10.1038/s41467-021-27686-7

N/A

0DataRank · unranked

30 citations

Danièle Gadelle, Keli Agama, Evgeny Kiselev, Hongliang Zhang, Emilie Yab +5 more

Structural and biochemical basis for DNA and RNA catalysis by human Topoisomerase 3β

Nature Communications(2022)10.1038/s41467-022-32221-3

N/A

0DataRank · unranked

22 citations

Sourav Saha, Wei Yang, Keir C. Neuman, Yves Pommier, Xi Yang

Functional characterization of two variants of mitochondrial topoisomerase TOP1MT that impact regulation of the mitochondrial genome

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102420

N/A

0DataRank · unranked

19 citations

Jingti Deng, Andrew Symes, Marina Kerr, Hongliang Zhang, Shar-yin N. Huang +4 more

Epigenetic upregulation of Schlafen11 renders WNT- and SHH-activated medulloblastomas sensitive to cisplatin

Neuro-Oncology(2022)10.1093/neuonc/noac243

N/A

0DataRank · unranked

19 citations

Junko Murai, Masayasu Okada, Haruhiko Takahashi, Tyler H Findlay, Kristen Malebranche +35 more

Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity

Bioorganic Chemistry(2022)10.1016/j.bioorg.2022.105789

N/A

0DataRank · unranked

11 citations

Fang‐Ting Wang, Min Wu, Wenjie Wang, Keli Agama, Yves Pommier +2 more

SUMO: A Swiss Army Knife for Eukaryotic Topoisomerases

Frontiers in Molecular Biosciences(2022)10.3389/fmolb.2022.871161

N/A

0DataRank · unranked

15 citations

John L. Nitiss, Yves Pommier, Yilun Sun

CDK7 Inhibition Synergizes with Topoisomerase I Inhibition in Small Cell Lung Cancer Cells by Inducing Ubiquitin-Mediated Proteolysis of RNA Polymerase II

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0891

N/A

0DataRank · unranked

15 citations

Yang Zhang, Christopher W. Schultz, Yves Pommier, Anish Thomas, Yilun Sun

PLX038: A Long-Acting Topoisomerase I Inhibitor With Robust Antitumor Activity in ATM -Deficient Tumors and Potent Synergy With PARP Inhibitors

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-22-0217

N/A

0DataRank · unranked

11 citations

Shaun D. Fontaine, Morgan E. Diolaiti, Parth Desai, Rajesh Kumar, Nobuyuki Takahashi +9 more

Targeting radioresistance and replication fork stability in prostate cancer

JCI Insight(2022)10.1172/jci.insight.152955

N/A

0DataRank · unranked

9 citations

GuemHee Baek, Suzanne Carreira, Wei Yuan, Shihong Ma, Mia Hofstad +12 more

Nucleosome destabilization by polyamines

Archives of Biochemistry and Biophysics(2022)10.1016/j.abb.2022.109184

N/A

0DataRank · unranked

8 citations

Erfaneh Firouzi Niaki, Rosevalentine Bosire, Péter P. Nánási, Péter Nagy, Zsolt Bacsó +5 more

Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1

Frontiers in Chemistry(2022)10.3389/fchem.2022.910953

N/A

0DataRank · unranked

8 citations

Wenjie Wang, G.T. Lountos, Joseph E. Tropea, D. Needle, Yves Pommier +2 more

SLFN11’s surveillance role in protein homeostasis

Oncoscience(2022)10.18632/oncoscience.560

N/A

0DataRank · unranked

1 citations

Ukhyun Jo, Yasuhiro Arakawa, Naoko Takebe, Yves Pommier, Yasuhisa Murai

Cancer/Testis Antigen 55 is required for cancer cell proliferation and mitochondrial DNA maintenance

Mitochondrion(2022)10.1016/j.mito.2022.02.005

N/A

0DataRank · unranked

3 citations

David Goudenège, Simone A. Baechler, Shar-yin N. Huang, Naïg Guéguen, Valérie Desquiret‐Dumas +9 more

Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.08.483326

N/A

0DataRank · unranked

3 citations

Jingti Deng, Yuanjiu Lei, Sylvia Torres-Odio, Gladys R. Rojas, Laura Newman +11 more

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes

Research Square(2022)10.21203/rs.3.rs-1570399/v1

N/A

0DataRank · unranked

0 citations

Sourav Saha, Xi Yang, Shar-yin N. Huang, Yilun Sun, Yves Pommier +1 more

BRCAness, Homologous Recombination Deficiencies, and Synthetic Lethality

Cancer Research(2023)10.1158/0008-5472.can-23-0628

N/A

0DataRank · unranked

131 citations

Yves Pommier, Junko Murai

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and Is Associated with Worse Outcomes

Cancer Discovery(2023)10.1158/2159-8290.cd-22-0796

N/A

0DataRank · unranked

118 citations

Christopher W. Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E. Redon, Nobuyuki Takahashi +32 more

New Life of Topoisomerase I Inhibitors as Antibody–Drug Conjugate Warheads

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-22-3640

N/A

0DataRank · unranked

58 citations

Anish Thomas, Yves Pommier

Targeting Replication Stress and Chemotherapy Resistance with a Combination of Sacituzumab Govitecan and Berzosertib: A Phase I Clinical Trial

Clinical Cancer Research(2023)10.1158/1078-0432.ccr-23-0536

N/A

0DataRank · unranked

38 citations

Nobuyuki Takahashi, Cody J. Peer, Christophe E. Redon, Samantha Nichols, Rasa Vilimas +30 more

Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT

Human Molecular Genetics(2023)10.1093/hmg/ddad062

N/A

0DataRank · unranked

35 citations

Jingti Deng, Yuanjiu Lei, Sylvia Torres-Odio, Gladys R. Rojas, Laura Newman +11 more

Targeting neddylation sensitizes colorectal cancer to topoisomerase I inhibitors by inactivating the DCAF13-CRL4 ubiquitin ligase complex

Nature Communications(2023)10.1038/s41467-023-39374-9

N/A

0DataRank · unranked

28 citations

Simone A. Baechler, Xiaohu Zhang, Suresh Kumar, Valentina M. Factor, Yasuhiro Arakawa +20 more

R-loops, type I topoisomerases and cancer

NAR Cancer(2023)10.1093/narcan/zcad013

N/A

0DataRank · unranked

26 citations

Yves Pommier, Sourav Saha

Replication-associated formation and repair of human topoisomerase IIIα cleavage complexes

Nature Communications(2023)10.1038/s41467-023-37498-6

N/A

0DataRank · unranked

24 citations

Sourav Saha, Xi Yang, Shar-yin N. Huang, Yilun Sun, Ukhyun Jo +2 more

Proteomic Dynamics of Breast Cancer Cell Lines Identifies Potential Therapeutic Protein Targets

Molecular & Cellular Proteomics(2023)10.1016/j.mcpro.2023.100602

N/A

0DataRank · unranked

20 citations

Weigang Ge, Yi Zhu, Azin Sayad, Augustin Luna, Mengge Lyu +17 more

Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency

Neuro-Oncology Advances(2023)10.1093/noajnl/vdad102

N/A

0DataRank · unranked

16 citations

Madison Butler, Zach Sergi, Robert W. Robey, Meili Zhang, Raj Chari +20 more

Identification and characterization of topoisomerase III beta poisons

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2218483120

N/A

0DataRank · unranked

15 citations

Sourav Saha, Xi Yang, Yves Pommier, Shar-yin N. Huang, Wenjie Wang

The TDRD3-USP9X complex and MIB1 regulate TOP3B homeostasis and prevent deleterious TOP3B cleavage complexes

Nature Communications(2023)10.1038/s41467-023-43151-z

N/A

0DataRank · unranked

15 citations

Shar-yin N. Huang, Xi Yang, Liton Kumar Saha, Yilun Sun, Prashant Khandagale +3 more

Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication

Molecular Cancer Therapeutics(2023)10.1158/1535-7163.mct-22-0552

N/A

0DataRank · unranked

11 citations

Michele Ceribelli, Haiqing Fu, Christophe E. Redon, Ukhyun Jo, Yasuhisa Murai +4 more

Synthesis and Biological Activities of 11‐ and 12‐Substituted Benzophenanthridinone Derivatives as DNA Topoisomerase IB and Tyrosyl‐DNA Phosphodiesterase 1 Inhibitors

ChemMedChem(2023)10.1002/cmdc.202200593

N/A

0DataRank · unranked

10 citations

Chao Qin, Min Wu, Fang‐Ting Wang, Wenjie Wang, Keli Agama +4 more

Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification

RSC Chemical Biology(2023)10.1039/d2cb00230b

N/A

0DataRank · unranked

10 citations

Wenjie Wang, G.T. Lountos, Evgeny Kiselev, Joseph E. Tropea, D. Needle +3 more

Real-time imaging of drug-induced trapping of cellular topoisomerases and poly(ADP-ribose) polymerase 1 at the single-molecule level

Nucleic Acids Research(2023)10.1093/nar/gkad735

N/A

0DataRank · unranked

8 citations

Jiji Chen, Yves Pommier, Yilun Sun

Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts

Nucleic Acids Research(2023)10.1093/nar/gkad837

N/A

0DataRank · unranked

5 citations

Laurent Cattiaux, Thomas Lavergne, Yves Pommier, Sophie Bombard, Anton Granzhan +1 more

HTLV-1 bZIP factor impairs DNA mismatch repair system

Biochemical and Biophysical Research Communications(2023)10.1016/j.bbrc.2023.03.049

N/A

0DataRank · unranked

3 citations

Takashi Sakamoto, Masayuki Kobayashi, Yoko Takiuchi, Fumie Iwai, Kohei Tada +12 more

Natural history study and tissue procurement of neuroendocrine neoplasms (NENs).

Journal of Clinical Oncology(2023)10.1200/jco.2023.41.4_suppl.tps659

N/A

0DataRank · unranked

0 citations

Briana Cortez, Diana Grace Varghese, Amirkia Naimian, Tamika Magee, Sarah Kelley +5 more

Data from Nonclassic Functions of Human Topoisomerase I: Genome-Wide and Pharmacologic Analyses

(2023)10.1158/0008-5472.c.6495548.v1

N/A

0DataRank · unranked

0 citations

Audrey Player, Uma Shankavaram, Yonghong Wang, Drazen B. Zimonjic, Philip L. Lorenzi +13 more

Data from Nonclassic Functions of Human Topoisomerase I: Genome-Wide and Pharmacologic Analyses

(2023)10.1158/0008-5472.c.6495548

N/A

0DataRank · unranked

0 citations

Audrey Player, Uma Shankavaram, Yonghong Wang, Drazen B. Zimonjic, Philip L. Lorenzi +13 more

Data from DNA fingerprinting of the NCI-60 cell line panel

(2023)10.1158/1535-7163.c.6532167

Top 100%

0DataRank

Top 100%0 citations

William C. Reinhold, Sudhir Varma, Amy Hutchinson, Yves Pommier, Stephen J. Chanock +2 more

Data from DNA fingerprinting of the NCI-60 cell line panel

(2023)10.1158/1535-7163.c.6532167.v1

Top 100%

0DataRank

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William C. Reinhold, Sudhir Varma, Amy Hutchinson, Yves Pommier, Stephen J. Chanock +2 more

Data from SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243

(2023)10.1158/0008-5472.c.6513573.v1

N/A

0DataRank · unranked

0 citations

Ukhyun Jo, Junko Murai, Lisa M. Jenkins, Shar-yin N. Huang, Sirisha Chakka +6 more

Data from Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2023)10.1158/1535-7163.c.6531693.v1

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0DataRank

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Anna Maria Calcagno, Chung‐Pu Wu, Sudhir Varma, Joanna H. Shih, Min Lin +7 more

Data from Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2023)10.1158/1535-7163.c.6531693

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0DataRank

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Anna Maria Calcagno, Chung‐Pu Wu, Sudhir Varma, Joanna H. Shih, Min Lin +7 more

The Novel ATR Inhibitor M1774 Induces Replication Protein Overexpression and Broad Synergy with DNA-targeted Anticancer Drugs

Molecular Cancer Therapeutics(2024)10.1158/1535-7163.mct-23-0402

N/A

0DataRank · unranked

24 citations

Yasuhiro Arakawa, Astrid Zimmermann, Daiki Taniyama, Makito Mizunuma, Lisa M. Jenkins +6 more

Activity of the Ubiquitin-activating Enzyme Inhibitor TAK-243 in Adrenocortical Carcinoma Cell Lines, Patient-derived Organoids, and Murine Xenografts

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0085

N/A

0DataRank · unranked

13 citations

Ukhyun Jo, Suresh Kumar, Nai-Yun Sun, Fathi Elloumi, Anish Thomas +18 more

Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4

Cancer Research Communications(2024)10.1158/2767-9764.crc-24-0093

N/A

0DataRank · unranked

13 citations

Christophe E. Redon, Liton Kumar Saha, Andy D. Tran, Anjali Dhall, Robin Sebastian +6 more

Sarcoma_CellminerCDB: A tool to interrogate the genomic and functional characteristics of a comprehensive collection of sarcoma cell lines

iScience(2024)10.1016/j.isci.2024.109781

N/A

0DataRank · unranked

10 citations

Christine M. Heske, Fathi Elloumi, Lőrinc Sándor Pongor, Prashant Khandagale, Sudhir Varma +6 more

TOP3A coupling with replication forks and repair of TOP3A cleavage complexes

Cell Cycle(2024)10.1080/15384101.2024.2314440

N/A

0DataRank · unranked

9 citations

Yves Pommier, Liton Kumar Saha

Targeted sulfur(VI) fluoride exchange-mediated covalent modification of a tyrosine residue in the catalytic pocket of tyrosyl-DNA phosphodiesterase 1

Communications Chemistry(2024)10.1038/s42004-024-01298-w

N/A

0DataRank · unranked

7 citations

I Barakat, G.T. Lountos, Wenjie Wang, Keli Agama, Md Rasel Al Mahmud +5 more

Metabolism‐focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer

Molecular Carcinogenesis(2024)10.1002/mc.23705

N/A

0DataRank · unranked

6 citations

Renzo Cavero, Yue Liu, Haojian Li, Xia Xu, Þorkell Andrésson +9 more

PARP1-driven repair of topoisomerase IIIα DNA-protein crosslinks by FEN1

Cell Reports(2024)10.1016/j.celrep.2024.114522

N/A

0DataRank · unranked

6 citations

Yilun Sun, Sourav Saha, Xi Yang, Yves Pommier, Liton Kumar Saha

Staufen1 Represses the FOXA1-Regulated Transcriptome by Destabilizing FOXA1 mRNA in Colorectal Cancer Cells

Molecular and Cellular Biology(2024)10.1080/10985549.2024.2307574

N/A

0DataRank · unranked

4 citations

Xiao Ling Li, Ragini Singh, Meira S. Zibitt, Corrine Corrina R. Hartford, Lőrinc Sándor Pongor +11 more

Metastatic organotropism in small cell lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.07.617066

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0DataRank · unranked

4 citations

Anjali Dhall, Sarthak Sahoo, Christopher W. Schultz, Michelle A. Baird, Parth Desai +33 more

Mitochondrial topoisomerase I (Top1MT) prevents the onset of metabolic dysfunction-associated steatohepatitis (MASH) in mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.05.611454

N/A

0DataRank · unranked

0 citations

LK Saha, VM Factor, Chetan E. Chitnis, Aseem Dhall, Doreen Becker +3 more

Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response

Frontiers in Cell and Developmental Biology(2024)10.3389/fcell.2024.1462840

N/A

0DataRank · unranked

0 citations

Ludmila Szabova, Victor J. Collins, Melanie B. Gordon, Kristine Johnson, Deborah B. Householder +15 more

SLFN11-mediated ribosome biogenesis impairment induces TP53-independent apoptosis

Molecular Cell(2025)10.1016/j.molcel.2025.01.008

N/A

0DataRank · unranked

31 citations

Keiichi Izumikawa, Sota Tate, Sho Isoyama, Mori Masaru, Kohei Fujiwara +22 more

Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics

Nature Communications(2025)10.1038/s41467-025-55959-y

N/A

0DataRank · unranked

15 citations

Xuemin Chen, Wei Yang, Yves Pommier, Xi Yang

Flap endonuclease 1 repairs DNA-protein cross-links via ADP-ribosylation–dependent mechanisms

Science Advances(2025)10.1126/sciadv.ads2919

N/A

0DataRank · unranked

8 citations

Lisa M. Jenkins, Lara H. El Touny, Linying Zhu, Xi Yang, Ukhyun Jo +10 more

Acetalax and Bisacodyl for the Treatment of Triple-Negative Breast Cancer: A Combined Molecular and Preclinical Study

Cancer Research Communications(2025)10.1158/2767-9764.crc-24-0435

N/A

0DataRank · unranked

7 citations

Elisabetta Marangoni, Fathi Elloumi, Rémi Montagne, Sudhir Varma, Yanghsin Wang +11 more

Topoisomerase IIIα controls alternative lengthening of telomeres

Cell Reports(2025)10.1016/j.celrep.2025.116066

N/A

0DataRank · unranked

5 citations

Yilun Sun, Daiki Taniyama, Sourav Saha, Liton Kumar Saha, Yves Pommier +1 more

Application of a bivalent “click” approach to target tyrosyl-DNA phosphodiesterase 1 (TDP1)

RSC Medicinal Chemistry(2025)10.1039/d4md00824c

N/A

0DataRank · unranked

4 citations

Wenjie Wang, Md Rasel Al Mahmud, Keli Agama, Yves Pommier, Terrence R. Burke +1 more

Lamin A/C loss promotes R-loop-mediated genomic instability and poor survival in small-cell lung cancer

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2503387122

N/A

0DataRank · unranked

4 citations

Sourav Saha, Anjali Dhall, Yang Zhang, Parth Desai, Lőrinc Sándor Pongor +31 more

Tumor-targeted top1 inhibitor delivery with optimized parp inhibition in advanced solid tumors: a phase i trial of gapped scheduling

Nature Communications(2025)10.1038/s41467-025-64509-5

N/A

0DataRank · unranked

3 citations

Nobuyuki Takahashi, Lenka Oplustil O’Connor, Christophe E. Redon, Chirayu Mohindroo, Linda Sciuto +8 more

Protocol to set up the CellMinerCDB pharmacogenomics analysis web application with custom cell line data

STAR Protocols(2025)10.1016/j.xpro.2025.104076

N/A

0DataRank · unranked

2 citations

Camille Tlemsani, Christine M. Heske, Lőrinc Sándor Pongor, Prashant Khandagale, Sudhir Varma +6 more

Topoisomerase III-beta protects from immune dysregulation and tumorigenesis

Science Advances(2025)10.1126/sciadv.ady7028

N/A

0DataRank · unranked

2 citations

Simone A. Baechler, Anjali Dhall, Sourav Saha, Hongliang Zhang, Laura Bassel +11 more

Beyond the Promoter: Total MGMT Gene Methylation Modulates Response to DNA-Alkylating Agents in Glioma

Molecular Cancer Therapeutics(2025)10.1158/1535-7163.mct-24-0977

N/A

0DataRank · unranked

2 citations

Jinkyu Jung, Aiguo Li, Chunzhang Yang, Mioara Larion, Lőrinc Sándor Pongor +7 more

Potent β-lactam-based tyrosyl-DNA phosphodiesterase 1 inhibitors identified by a virtual screen

Scientific Reports(2025)10.1038/s41598-025-12503-8

N/A

0DataRank · unranked

1 citations

Wenjie Wang, Kiall F. Suazo, Md Rasel Al Mahmud, Keli Agama, G.T. Lountos +4 more

Bimodal genomic approach predicting Semaphorin 7A (SEMA7A) as prognostic biomarker in adrenocortical carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.03.647086

N/A

0DataRank · unranked

1 citations

Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Suresh Kumar +7 more

Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma

Cancers(2025)10.3390/cancers17132078

N/A

0DataRank · unranked

0 citations

Daiki Taniyama, Fathi Elloumi, Augustin Luna, Sudhir Varma, Suresh Kumar +9 more

Discovery of thiacyanine dyes as a new class of potent coronavirus inhibitors that suppress viral RNA synthesis

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110547

N/A

0DataRank · unranked

0 citations

Valerie Altouma, Joshua A. Sommers, Adaira J Dumm, Debbie R. Kennedy, Hongjie Xia +14 more

New Approaches to SCLC Therapy: From the Laboratory to the Clinic

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.01.016

N/A

0DataRank · unranked

177 citations

Julie George, Taofeek K. Owonikoko, Anton Berns, Élisabeth Brambilla, Lauren A. Byers +42 more

CellMiner cross-database (CellMinerCDB) version 2.2 for explorations of patient-derived cancer cell line pharmacogenomics

Nucleic Acids Research(2025)10.1093/nar/gkaf1230

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William C. Reinhold, Sudhir Varma, Yanghsin Wang, Meric Kinali, Yasuhiro Arakawa +5 more

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Science Translational Medicine(2020)10.1126/scitranslmed.aax2625

N/A

0DataRank · unranked

148 citations

Rania El Botty, Sophie Château‐Joubert, Ahmed Dahmani, Élodie Montaudon, Sophie Leboucher +29 more

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

Science Advances(2020)10.1126/sciadv.aba6290

N/A

0DataRank · unranked

143 citations

Lisa M. Jenkins, Yijun Su, Karin C. Nitiss, John L. Nitiss, Yves Pommier +1 more

MGMT Status as a Clinical Biomarker in Glioblastoma

Trends in cancer(2020)10.1016/j.trecan.2020.02.010

N/A

0DataRank · unranked

350 citations

Lőrinc Sándor Pongor, Yuting Su, Liqiang Xi, Mark Raffeld, Martha Quezado +5 more

Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC)

DNA repair(2020)10.1016/j.dnarep.2020.102837

N/A

0DataRank · unranked

105 citations

Sourav Saha, Wenjie Wang, Liton Kumar Saha, Shar-yin N. Huang, Yves Pommier +1 more

Debulking of topoisomerase DNA-protein crosslinks (TOP-DPC) by the proteasome, non-proteasomal and non-proteolytic pathways

DNA repair(2020)10.1016/j.dnarep.2020.102926

N/A

0DataRank · unranked

90 citations

Liton Kumar Saha, Sourav Saha, Ukhyun Jo, Yves Pommier, Yilun Sun

Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

Clinical Epigenetics(2020)10.1186/s13148-020-00876-8

N/A

0DataRank · unranked

88 citations

Thomas Silvers, William C. Reinhold, Dmitriy Sonkin, Suleyman Vural, John Connelly +8 more

Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

Cell Reports(2020)10.1016/j.celrep.2020.02.117

N/A

0DataRank · unranked

87 citations

Hongliang Zhang, Lőrinc Sándor Pongor, Sai-Wen Tang, Ukhyun Jo, Fumiya Moribe +4 more

BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks

Epigenetics & Chromatin(2020)10.1186/s13072-020-00343-x

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0DataRank · unranked

72 citations

Jacob Gross, Roberto Vera Alvarez, Junko Murai, Sang‐Min Jang, Hongliang Zhang +10 more

Sensitivity of Mesothelioma Cells to PARP Inhibitors Is Not Dependent on BAP1 but Is Enhanced by Temozolomide in Cells With High-Schlafen 11 and Low-O6-methylguanine-DNA Methyltransferase Expression

Journal of Thoracic Oncology(2020)10.1016/j.jtho.2020.01.012

N/A

0DataRank · unranked

68 citations

Manakamana Khanal, Junko Murai, Jingli Zhang, Manjistha Sengupta, Qun Jiang +13 more

Resistance to the CHK1 inhibitor prexasertib involves functionally distinct CHK1 activities in BRCA wild-type ovarian cancer

Oncogene(2020)10.1038/s41388-020-1383-4

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0DataRank · unranked

59 citations

Tzu‐Ting Huang, Junko Murai, Brittany Haynes, Patricia S. Steeg, Yves Pommier +2 more

Immunohistochemical analysis of SLFN11 expression uncovers potential non-responders to DNA-damaging agents overlooked by tissue RNA-seq

Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin(2020)10.1007/s00428-020-02840-6

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54 citations

Naoya Sakamoto, Junko Murai, Daiki Taniyama, Ririno Honma, Shoichi Ukai +6 more

DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks

Cell Reports(2020)10.1016/j.celrep.2020.108569

N/A

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55 citations

Yilun Sun, Shar-yin N. Huang, Simone A. Baechler, Lőrinc Sándor Pongor, Keli Agama +5 more

Epigenetic Regulation of DNA Repair Pathway Choice by MacroH2A1 Splice Variants Ensures Genome Stability

Molecular Cell(2020)10.1016/j.molcel.2020.06.028

N/A

0DataRank · unranked

47 citations

Eri K. Hosogane, Eric G. Sun, Andy D. Tran, William C. Reinhold, Sandra Burkett +6 more

Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I

Journal of the American Chemical Society(2020)10.1021/jacs.0c10418

N/A

0DataRank · unranked

20 citations

Brice A. P. Wilson, Christophe Marchand, Suthananda N. Sunassee, Alun Bermingham, Wenjie Wang +9 more

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