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Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair–targeted therapies

Science Translational Medicine(2021)10.1126/scitranslmed.abc7488Source: DataRank Database

Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair–targeted therapies is a research paper published in Science Translational Medicine (2021). On theSindex it has a DataRank of 0. It has been cited 73 times.

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0DataRank · unranked

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Open Access73 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 4.46)OA: greenTopics (39)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (25)

Nobuyuki Takahashi ORCID,Lőrinc Sándor Pongor ORCID,Vinodh N. Rajapakse ORCID,Manoj Tyagi ORCID,Xinyu Wen ORCID

Live enrichment

PubMed:33504652 PMC:PMC8489678 OpenAlex:https://openalex.org/W3125037687

National Cancer Institute

Grant: ZIA BC 011793

Intramural NIH HHS

Grant: ZID BC011908

FWCI

4.46

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

green

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8489678

publisherhttps://syndication.highwire.org/content/doi/10.1126/scitranslmed.abc7488

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.abc7488

journalhttps://doi.org/10.1126/scitranslmed.abc7488

Fields of Study

Lung Cancer Research StudiesChromatin Remodeling and CancerNeuroendocrine Tumor Research AdvancesBRCA1 ProteinBRCA2 ProteinDNA RepairGenetic Predisposition to DiseaseGerm-Line MutationHumansLung NeoplasmsNeoplasm Recurrence, LocalSmall Cell Lung CarcinomaExome Sequencing

MeSH Terms

Exome SequencingDNA RepairHumansLung NeoplasmsNeoplasm Recurrence, LocalGerm-Line MutationBRCA1 ProteinGenetic Predisposition to DiseaseBRCA2 ProteinSmall Cell Lung Carcinoma

Keywords

Exome sequencingGermlineExomeLung cancerCancer researchMedicineGermline mutationDNA repairSynthetic lethalityMutationBiologyGeneticsDNABioinformaticsOncologyGene

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 1 of Genomic features of Chinese small cell lung cancer

10.6084/m9.figshare.19807901.v1figshare

Additional file 1 of Genomic features of Chinese small cell lung cancer

10.6084/m9.figshare.19807901figshare