Zhong‐Yin Zhang

Biochemistry, Genetics and Molecular BiologyImmunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 76 papers. Top paper: “Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2”.

Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.010274

N/A

0.886DataRank · unranked

23 citations

Zhihong Yu, Lan Chen, Chad D. Walls, Sheng Zhang, Li Wu +2 more

PTP-MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates

EMBO Reports(2021)10.15252/embr.202052141

N/A

0.369DataRank · unranked

8 citations

Xu Chen, Zhao Yang, Peng Xiao, Chunhua Liu, Kangshuai Li +15 more

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

Angewandte Chemie International Edition(2025)10.1002/anie.202525126

N/A

0.112DataRank · unranked

1 citations

Frederick Nguele Meke, Zheng Zhang, Zhong‐Yin Zhang, Aaron D. Krabill, Christine S. Muli +12 more

Acquisition of a Potent and Selective TC-PTP Inhibitor via a Stepwise Fluorophore-Tagged Combinatorial Synthesis and Screening Strategy

UNC Libraries(2020)10.17615/js8s-cy37

N/A

0DataRank · unranked

3 citations

Andrea Gunawan, Lan Chen, David S. Lawrence, Zhong‐Yin Zhang, Yong Luo +1 more

How mu-Opioid Receptor Recognizes Fentanyl

Research Square(2020)10.21203/rs.3.rs-67888/v1

N/A

0DataRank · unranked

9 citations

Paween Mahinthichaichan, Zhong‐Yin Zhang, Christopher D. Ellis, Quynh N. Vo

Continuous constant pH Molecular Dynamics Simulations of Transmembrane Proteins

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.06.239772

N/A

0DataRank · unranked

5 citations

Jack A. Henderson, Zhong‐Yin Zhang, Yandong Huang

Exploring the pH-dependent structure-dynamics-function relationship of human renin

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.15.340935

N/A

0DataRank · unranked

1 citations

Jack A. Henderson, Zhong‐Yin Zhang, Shuhua Ma

How μ-opioid receptor recognizes fentanyl

Nature Communications(2021)10.1038/s41467-021-21262-9

N/A

0DataRank · unranked

122 citations

Paween Mahinthichaichan, Zhong‐Yin Zhang, Christopher R. Ellis, Quynh N. Vo

Systemic inhibition of PTPN22 augments anticancer immunity

Journal of Clinical Investigation(2021)10.1172/jci146950

N/A

0DataRank · unranked

53 citations

Sarah Croessmann, Jianping Lin, Zaw Phyo, Soren Charmsaz, Ludmila Danilova +18 more

Profiling MAP kinase cysteines for targeted covalent inhibitor design

RSC Medicinal Chemistry(2021)10.1039/d1md00277e

N/A

0DataRank · unranked

19 citations

Neha Verma, Jack A. Henderson, Shaoqi Zhan, Zhong‐Yin Zhang, Ruibin Liu

Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation

iScience(2021)10.1016/j.isci.2021.103310

N/A

0DataRank · unranked

19 citations

Yunpeng Bai, Kunpeng Li, Ovini Amarasinghe, Wen Jiang, Zhong‐Yin Zhang +1 more

Advancements in chemical biology targeting the kinases and phosphatases of RNA polymerase II-mediated transcription

Current Opinion in Chemical Biology(2021)10.1016/j.cbpa.2021.02.002

N/A

0DataRank · unranked

3 citations

Blase M. LeBlanc, Wendy L. Matthews, Zhong‐Yin Zhang, Yan Zhang, Wantae Kim

Kinetics and Mechanism of Fentanyl Dissociation from the µ -Opioid Receptor

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.25.441335

N/A

0DataRank · unranked

0 citations

Quynh N. Vo, Christopher R. Ellis, Zhong‐Yin Zhang, Paween Mahinthichaichan

GPU-Accelerated All-Atom Particle-Mesh Ewald Continuous Constant pH Molecular Dynamics in Amber

Journal of Chemical Theory and Computation(2022)10.1021/acs.jctc.2c00586

N/A

0DataRank · unranked

100 citations

Ruibin Liu, Vinícius M. de Oliveira, Erik Antonio Vázquez-Montelongo, Jack A. Henderson, Zhong‐Yin Zhang +1 more

Constant pH molecular dynamics simulations: Current status and recent applications

Current Opinion in Structural Biology(2022)10.1016/j.sbi.2022.102498

N/A

0DataRank · unranked

96 citations

Ruibin Liu, Zhong‐Yin Zhang, Vinícius M. de Oliveira

Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

Neuron(2022)10.1016/j.neuron.2022.10.028

N/A

0DataRank · unranked

79 citations

Chao Yang, Xuejie Wang, Jinmin Miao, Weitao Chen, Yiren Zhou +13 more

PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371

Blood(2022)10.1182/blood.2022016580

N/A

0DataRank · unranked

16 citations

Yunpeng Bai, Michihiro Kobayashi, Shiyu Xiao, Wenjie Cai, Sergio Barajas +21 more

PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805

Autophagy(2022)10.1080/15548627.2022.2140558

N/A

0DataRank · unranked

16 citations

Guimei Yu, Hongming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu +8 more

The Toxoplasma glucan phosphatase TgLaforin utilizes a distinct functional mechanism that can be exploited by therapeutic inhibitors

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102089

N/A

0DataRank · unranked

15 citations

Tiantian Chen, Jianping Lin, Rongjun He, Li Wu, Caden R. Pearson +7 more

Exploration of beta-arrestin isoform signaling pathways in delta opioid receptor agonist-induced convulsions

Frontiers in Pharmacology(2022)10.3389/fphar.2022.914651

N/A

0DataRank · unranked

8 citations

Yiming Miao, Jinling Yuan, Sophia Palant, Rebecca J. Liu, Zhong‐Yin Zhang +2 more

H172Y mutation perturbs the S1 pocket and nirmatrelvir binding of SARS-CoV-2 main protease through a nonnative hydrogen bond

Research Square(2022)10.21203/rs.3.rs-1915291/v1

N/A

0DataRank · unranked

12 citations

Mohamed Ibrahim, Xinyuanyuan Sun, Rolf Hilgenfeld, Zhong‐Yin Zhang, Vinícius de Oliveira

GPU-Accelerated All-atom Particle-Mesh Ewald Continuous Constant pH Molecular Dynamics in Amber

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.04.494833

N/A

0DataRank · unranked

4 citations

Ruibin Liu, Vinícius M. de Oliveira, Erik Vaquez Montelongo, Jack A. Henderson, Zhong‐Yin Zhang +1 more

An Integrative Approach to Dissect the Drug Resistance Mechanism of the H172Y Mutation of SARS-CoV-2 Main Protease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.31.502215

N/A

0DataRank · unranked

2 citations

Vinícius M. de Oliveira, Mohamed Fouad Ibraham, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen +3 more

Establishment and characterization of patient-derived xenograft from leptomeningeal spread of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion

Research Square(2022)10.21203/rs.3.rs-2026518/v1

N/A

0DataRank · unranked

0 citations

Reza Saadatzadeh, Erika A. Dobrota, Josue D. Ordaz, Barbara J. Bailey, Pankita H. Pandya +17 more

Integrative Approach to Dissect the Drug Resistance Mechanism of the H172Y Mutation of SARS-CoV-2 Main Protease

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c00344

N/A

0DataRank · unranked

22 citations

Vinícius M. de Oliveira, Mohamed Fouad Ibrahim, Xinyuanyuan Sun, Paween Mahinthichaichan, Mingzhe Shen +3 more

Quantum Descriptors for Predicting and Understanding the Structure–Activity Relationships of Michael Acceptor Warheads

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c00720

N/A

0DataRank · unranked

12 citations

Erik Antonio Vázquez-Montelongo, Shuhua Ma, Zhong‐Yin Zhang, Ruibin Liu

SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease

Alzheimer s & Dementia Translational Research & Clinical Interventions(2023)10.1002/trc2.12429

N/A

0DataRank · unranked

12 citations

Emily R. Mason, Shaoyou Chu, Adrian L. Oblak, June Javens‐Wolfe, Mustapha Moussaif +23 more

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology(2023)10.1111/bph.16304

N/A

0DataRank · unranked

10 citations

Jiajun Dong, Zhong‐Yin Zhang, Zihan Qu

PRL2 inhibition elevates PTEN protein and ameliorates progression of acute myeloid leukemia

JCI Insight(2023)10.1172/jci.insight.170065

N/A

0DataRank · unranked

9 citations

Yunpeng Bai, Allison Paige-Hood, Qinglin Li, Frederick Nguele Meke, Zhong‐Yin Zhang +1 more

Analysis of the ERK Pathway Cysteinome for Targeted Covalent Inhibition of RAF and MEK Kinases

Journal of Chemical Information and Modeling(2023)10.1021/acs.jcim.3c00014

N/A

0DataRank · unranked

7 citations

Ruibin Liu, Shaoqi Zhan, Joseph Clayton, Zhong‐Yin Zhang, Aarion Romany

Establishment and characterization of patient-derived xenograft of a rare pediatric anaplastic pleomorphic xanthoastrocytoma (PXA) bearing a CDC42SE2-BRAF fusion

Scientific Reports(2023)10.1038/s41598-023-36107-2

N/A

0DataRank · unranked

1 citations

M. Reza Saadatzadeh, Erika A. Dobrota, Josue D. Ordaz, Barbara J. Bailey, Pankita H. Pandya +17 more

A novel fluorogenic reporter substrate for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCγ2): Application to high-throughput screening for activators to treat Alzheimer's disease

SLAS DISCOVERY(2023)10.1016/j.slasd.2023.03.003

N/A

0DataRank · unranked

3 citations

Tadanobu Utsuki, Daniel E. Beck, Emma K. Lendy, Kuai-lin Sun, Yinghui Liu +5 more

High-Throughput Discovery and Characterization of Covalent Inhibitors for Protein Tyrosine Phosphatases

Methods in molecular biology(2023)10.1007/978-1-0716-3569-8_19

N/A

0DataRank · unranked

2 citations

Aaron D. Krabill, Zhong‐Yin Zhang, Zihan Qu

A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.16.545220

N/A

0DataRank · unranked

5 citations

Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen +9 more

Structure-Kinetics Relationships of Opioids from Metadynamics and Machine Learning

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.06.531338

N/A

0DataRank · unranked

2 citations

Ruibin Liu, Quynh N. Vo, Christopher R. Ellis, Lidiya Stavitskaya, Zhong‐Yin Zhang +1 more

Quantum Descriptors for Predicting and Understanding the Structure-Activity Relationships of Covalent Warheads

ChemRxiv(2023)10.26434/chemrxiv-2023-lh0qp

N/A

0DataRank · unranked

1 citations

Erik Vazquez-Montelongo, Shuhua Ma, Zhong‐Yin Zhang, Ruibin Liu

Constant-pH Simulations with the Polarizable Atomic Multipole AMOEBA Force Field

ChemRxiv(2023)10.26434/chemrxiv-2023-96z34

N/A

0DataRank · unranked

1 citations

Matthew J. Speranza, Sanika Jadhav, Lewis L. Stevens, Daniel K. Unruh, Pengyu Ren +4 more

Data from Activation of Src by Protein Tyrosine Phosphatase 1B Is Required for ErbB2 Transformation of Human Breast Epithelial Cells

(2023)10.1158/0008-5472.c.6499185.v1

N/A

0DataRank · unranked

0 citations

Sayanti Saha, Olga Villamar‐Cruz, Shu‐Chin Yip, Stephen P. Ethier, Zhong‐Yin Zhang +2 more

Quantum Descriptors for Predicting and Understanding the Structure-Activity Relationships of Michael Acceptor Warheads

ChemRxiv(2023)10.26434/chemrxiv-2023-lh0qp-v2

N/A

0DataRank · unranked

0 citations

Erik Vazquez-Montelongo, Shuhua Ma, Zhong‐Yin Zhang, Ruibin Liu

CHARMM at 45: Enhancements in Accessibility, Functionality, and Speed

The Journal of Physical Chemistry B(2024)10.1021/acs.jpcb.4c04100

N/A

0DataRank · unranked

116 citations

Steven L. Austin, Arnaud Blondel, Eric D. Boittier, Stefan Boresch, Matthias Buck +68 more

Constant-pH Simulations with the Polarizable Atomic Multipole AMOEBA Force Field

Journal of Chemical Theory and Computation(2024)10.1021/acs.jctc.3c01180

N/A

0DataRank · unranked

17 citations

Matthew J. Speranza, Sanika Jadhav, Lewis L. Stevens, Daniel K. Unruh, Pengyu Ren +4 more

Off-target autophagy inhibition by SHP2 allosteric inhibitors contributes to their antitumor activity in RAS-driven cancers

Journal of Clinical Investigation(2024)10.1172/jci177142

N/A

0DataRank · unranked

14 citations

Yunpeng Bai, Jinmin Miao, Allison A. Murray, Jianping Lin, Jiajun Dong +8 more

Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics

The Journal of Physical Chemistry B(2024)10.1021/acs.jpcb.4c05971

N/A

0DataRank · unranked

10 citations

Ruibin Liu, Zhong‐Yin Zhang, Craig A. Peeples

Natural product-inspired molecules for covalent inhibition of SHP2 tyrosine phosphatase

Tetrahedron(2024)10.1016/j.tet.2024.133918

N/A

0DataRank · unranked

9 citations

Aaron D. Krabill, Katelyn S. Gallagher, Christine S. Muli, Zihan Qu, Darci J. Trader +3 more

Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study

hLife(2024)10.1016/j.hlife.2024.06.003

N/A

0DataRank · unranked

9 citations

Xinyuanyuan Sun, Vinícius M. de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani +3 more

QM/MM Simulations of Afatinib-EGFR Addition: The Role of β-Dimethylaminomethyl Substitution

Journal of Chemical Theory and Computation(2024)10.1021/acs.jctc.4c00290

N/A

0DataRank · unranked

7 citations

Heeral Patel, Craig A. Peeples, Zhong‐Yin Zhang, Shuhua Ma

Interior pH-sensing residue of human voltage-gated proton channel Hv1 is histidine 168

Biophysical Journal(2024)10.1016/j.bpj.2024.07.027

N/A

0DataRank · unranked

7 citations

Yandong Huang, Zhitao Cai, Vladimir V. Cherny, Thomas E. DeCoursey, Zhong‐Yin Zhang +1 more

Machine Learned Classification of Ligand Intrinsic Activities at Human μ-Opioid Receptor

ACS Chemical Neuroscience(2024)10.1021/acschemneuro.4c00212

N/A

0DataRank · unranked

6 citations

Maximilian Shen, Ruibin Liu, Lidiya Stavitskaya, Zhong‐Yin Zhang, Myongin Oh

A novel micellular fluorogenic substrate for quantitating the activity of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (PLCγ) enzymes

PLoS ONE(2024)10.1371/journal.pone.0299541

N/A

0DataRank · unranked

2 citations

Tadanobu Utsuki, Daniel E. Beck, W. Brent Clayton, Emma K. Lendy, Kuai-lin Sun +6 more

Force Field X: A computational microscope to study genetic variation and organic crystals using theory and experiment

The Journal of Chemical Physics(2024)10.1063/5.0214652

N/A

0DataRank · unranked

1 citations

Aaron J. Nessler, Andrew Thiel, Hernan V. Bernabe, Rae Corrigan, Leah M. Cousineau +16 more

Valosin-Containing Protein (VCP)/p97 Oligomerization

Sub-cellular biochemistry/Subcellular biochemistry(2024)10.1007/978-3-031-58843-3_18

N/A

0DataRank · unranked

1 citations

Yunpeng Bai, Zhong‐Yin Zhang, Guimei Yu

Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K

Inorg. Mater. (Engl. Transl.); (United States)(2024)10.1101/2024.03.04.583178

N/A

0DataRank · unranked

4 citations

Xinyuanyuan Sun, Vinícius M. de Oliveira, Ruibin Liu, Joseph Clayton, Haifa El Kilani +3 more

Correlative Imaging for Comprehensive Molecular Mapping of Individual Cell Types in Biological Tissues

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.04.611280

N/A

0DataRank · unranked

3 citations

Mushfeqa Iqfath, Frederick Nguele Meke, Zihan Qu, Emerson L. Hernly, Pei Su +3 more

KaMLs for Predicting Protein p K a Values and Ionization States: Are Trees All You Need?

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.09.622800

N/A

0DataRank · unranked

3 citations

Daniel Kortzak, Simon Ambrozak, Shubham Bhatnagar, Ian Buchanan, Ruibin Liu +2 more

Force Field Limitations of All-Atom Continuous Constant pH Molecular Dynamics

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.03.611076

N/A

0DataRank · unranked

2 citations

Ruibin Liu, Zhong‐Yin Zhang, Craig A. Peeples

QM/MM simulations of EFGR with afatinib reveal the role of the β -dimethylaminomethyl substitution

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.18.580887

N/A

0DataRank · unranked

1 citations

Heeral Patel, Craig A. Peeples, Zhong‐Yin Zhang, Shuhua Ma

Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors

eLife(2024)10.7554/elife.95334

N/A

0DataRank · unranked

1 citations

Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I. Poulikakos, Zhong‐Yin Zhang +1 more

Machine Learned Classification of Ligand Intrinsic Activities at Human µ -Opioid Receptor

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.07.588485

N/A

0DataRank · unranked

1 citations

Maximilian Shen, Ruibin Liu, Lidiya Stavitskaya, Zhong‐Yin Zhang, Myongin Oh

A Putative Binding Model of Nitazene Derivatives at the μ -Opioid Receptor

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.10.03.616560

N/A

0DataRank · unranked

1 citations

Lei Shi, Michael J. Robertson, Georgios Skiniotis, Michael Michaelides, Lidiya Stavitskaya +2 more

New insights into the substrate recognition and transport mechanism of the human sodium-taurocholate cotransporter

Biophysical Journal(2024)10.1016/j.bpj.2024.04.024

N/A

0DataRank · unranked

0 citations

Zhong‐Yin Zhang

Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation

UNC Libraries(2024)10.17615/66tf-t772

N/A

0DataRank · unranked

0 citations

Mitsuhiko Ikura, Ivette Valencia-Sama, Benjamin Grant, Ming-Sound Tsao, Jonathan St‐Germain +14 more

Recent Developments in Amber Biomolecular Simulations

Journal of Chemical Information and Modeling(2025)10.1021/acs.jcim.5c01063

N/A

0DataRank · unranked

131 citations

David S. Cerutti, Vinícius Wilian D. Cruzeiro, Thomas A. Darden, Robert E. Duke, Mahdieh Ghazimirsaeed +26 more

A putative binding model of nitazene derivatives at the μ-opioid receptor

Neuropharmacology(2025)10.1016/j.neuropharm.2025.110437

N/A

0DataRank · unranked

11 citations

Lei Shi, Michael J. Robertson, Georgios Skiniotis, Michael Michaelides, Lidiya Stavitskaya +2 more

KaMLs for Predicting Protein p K a Values and Ionization States: Are Trees All You Need?

Journal of Chemical Theory and Computation(2025)10.1021/acs.jctc.4c01602

N/A

0DataRank · unranked

8 citations

Daniel Kortzak, Simon Ambrozak, Shubham Bhatnagar, Ian Buchanan, Ruibin Liu +2 more

Mechanism of dimer selectivity and binding cooperativity of BRAF inhibitors

eLife(2025)10.7554/elife.95334.4

N/A

0DataRank · unranked

5 citations

Aarion Romany, Evangelia Matenoglou, Evripidis Gavathiotis, Poulikos I. Poulikakos, Zhong‐Yin Zhang +1 more

Predicting Protein Electrostatics with Protein Language Models

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.17.649309

N/A

0DataRank · unranked

3 citations

Guy W. Dayhoff, Daniel Kortzak, Zhong‐Yin Zhang, Mingzhe Shen

Discovery of Chirally-dependent Protein O-2-Hydroxyglutarylation by D2HG and L2HG

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.24.634716

N/A

0DataRank · unranked

1 citations

Yi‐Kai Liu, Zhuojun Luo, Meng-Ju Wu, Claudia N. Evans, Zihan Qu +6 more

Protein Electrostatic Properties are Fine-Tuned Through Evolution

Research Square(2025)10.21203/rs.3.rs-6471091/v1

N/A

0DataRank · unranked

0 citations

Mingzhe Shen, Guy W. Dayhoff, Zhong‐Yin Zhang

Innate Immune Remodeling Drives Therapy Resistance via Macrophage–NK Cell Crosstalk

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.22.666055

N/A

0DataRank · unranked

0 citations

Keng-Jung Lee, Jingyi Chen, Leanne R. Donahue, Jianping Lin, Danielle Kacaj +3 more

Membrane Permeability Drives the Extreme Potency of Fentanyl but not Isotonitazene

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.22.666146

N/A

0DataRank · unranked

0 citations

George J. Farmer, Jacqueline R. Glenn, Shailesh N. Mistry, J. Robert Lane, Lei Shi +4 more

Illuminating the Druggable Human Proteome with an AI Protein Profiling Platform

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.07.670677

N/A

0DataRank · unranked

0 citations

Daniel Kortzak, Ruibin Liu, Mingzhe Shen, Zhong-Yin Zhang, Zhong‐Yin Zhang +1 more

Illuminating the Druggable Proteome with an AI Protein Profiling Platform

Research Square(2025)10.21203/rs.3.rs-7667948/v1

N/A

0DataRank · unranked

0 citations

Guy W. Dayhoff, Daniel Kortzak, Ruibin Liu, Mingzhe Shen, Zhong-Yin Zhang +1 more

Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation

Cell(2020)10.1016/j.cell.2020.09.002

N/A

0DataRank · unranked

275 citations

Jingjing Xie, Wenna Kong, Jingfei Xie, Yichen Li, Lin Du +19 more

Discovery of a First‐in‐Class Covalent Allosteric SHP1 Inhibitor with Immunotherapeutic Activity

Angewandte Chemie(2025)10.1002/ange.202525126

N/A

0DataRank · unranked

0 citations

Frederick Nguele Meke, Zheng Zhang, Aaron D. Krabill, Christine S. Muli, Brenson A. Jassim +12 more

Assessment of proton-coupled conformational dynamics of SARS and MERS coronavirus papain-like proteases: Implication for designing broad-spectrum antiviral inhibitors

The Journal of Chemical Physics(2020)10.1063/5.0020458

N/A

0DataRank · unranked

67 citations

Neha Verma, Robert C. Harris, Ruibin Liu, Zhong‐Yin Zhang, Jack A. Henderson

Alternative proton-binding site and long-distance coupling in Escherichia coli sodium–proton antiporter NhaA

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2005467117

N/A

0DataRank · unranked

39 citations

Yandong Huang, Oliver Beckstein, Zhong‐Yin Zhang, Jack A. Henderson