Mary F. Paine

Also affiliated with Interaction Design (United Kingdom)

Pharmacology, Toxicology and PharmaceuticsMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 4%percentile

0.805Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000054

Top 25%

0.805DataRank

Top 25%27 citations

Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley +4 more

Papers

Driven by 37 papers — median percentile 75. Top paper: “Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial”.

Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial

JAMA Network Open(2023)10.1001/jamanetworkopen.2022.54752

N/A

2.0DataRank · unranked

84 citations

Tory R. Spindle, Renuka Surujunarain, Elise M. Weerts, Sumit Bansal, Jashvant D. Unadkat +3 more

A New Data Repository for Pharmacokinetic Natural Product-Drug Interactions: From Chemical Characterization to Clinical Studies

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000054

Top 25%

0.805DataRank

Top 25%27 citations

Brandon T. Gufford, Eric Chou, Marijanel Alilio, Sidney VanAlstine, Rachael E. Morley +4 more

The Pharmacokinetic Interaction Between Metformin and the Natural Product Goldenseal Is Metformin Dose‐Dependent: A Three‐Arm Crossover Study in Adults With Type 2 Diabetes

Clinical and Translational Science(2025)10.1111/cts.70120

N/A

0.165DataRank · unranked

2 citations

Christopher M. Arian, Rakshit S. Tanna, Maxey G. Cherel, Matthew E. Layton, John R. White +3 more

Predicting the Potential for Cannabinoids to Precipitate Pharmacokinetic Drug Interactions via Reversible Inhibition or Inactivation of Major Cytochromes P450

Drug Metabolism and Disposition(2020)10.1124/dmd.120.000073

N/A

0DataRank · unranked

88 citations

Neha Maharao, Mary F. Paine, Jashvant D. Unadkat, Sumit Bansal

Modulation of Major Human Liver Microsomal Cytochromes P450 by Component Alkaloids of Goldenseal: Time-Dependent Inhibition and Allosteric Effects

Drug Metabolism and Disposition(2020)10.1124/dmd.120.091041

N/A

0DataRank · unranked

17 citations

Dandan Tian, Kenneth E. Thummel, Mary F. Paine, Allan E. Rettie, Matthew G. McDonald

Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations

Journal of Pharmacology and Experimental Therapeutics(2020)10.1124/jpet.120.000270

N/A

0DataRank · unranked

36 citations

Dandan Tian, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel +2 more

Altered morphine glucuronide and bile acid disposition in patients with nonalcoholic steatohepatitis

UNC Libraries(2020)10.17615/ggm4-4r76

N/A

0DataRank · unranked

4 citations

Curtis Johnston, Brian C. Ferslew, W-Y Jia, Kim L. R. Brouwer, Eleftheria Tsakalozou +4 more

Isolation and Identification of Intestinal CYP3A Inhibitors from Cranberry ( Vaccinium macrocarpon ) Using Human Intestinal Microsomes

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/9fh3-xh98

N/A

0DataRank · unranked

3 citations

Tyler N. Graf, Scott J. Brantley, Arlene A. Sy‐Cordero, Eun‐Kyung Kim, Nicholas H. Oberlies +1 more

Influence of Dietary Substances on Intestinal Drug Metabolism and Transport

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/pqrb-c894

N/A

0DataRank · unranked

0 citations

Mary F. Paine, Nicholas H. Oberlies, Christina S. Won

A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice-Fexofenadine Interaction: An In Vitro-In Vivo “Connect”: The Journal of Clinical Pharmacology

UNC Libraries(2020)10.17615/8ym0-mf79

N/A

0DataRank · unranked

0 citations

Paul A. Dawson, Tian Lan, Mary F. Paine, Wilbur Widmer, Yolanda V. Scarlett +3 more

Is quinine a suitable probe to assess the hepatic drug-metabolizing enzyme CYP3A4?

UNC Libraries(2020)10.17615/xzkz-9868

N/A

0DataRank · unranked

0 citations

Paul B. Watkins, Susan N. Pusek, Mary F. Paine, Sompon Wanwimolruk

Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice using Ultra Performance Liquid Chromatography

UNC Libraries(2020)10.17615/c549-5395

N/A

0DataRank · unranked

0 citations

Karen M. VanderMolen, Mary F. Paine, Nicholas H. Oberlies, Nadja B. Cech

Mechanisms underlying food–drug interactions: Inhibition of intestinal metabolism and transport

NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro)(2020)10.17615/8423-ec62

N/A

0DataRank · unranked

0 citations

Christina S. Won, Nicholas H. Oberlies, Mary F. Paine

Labeled content of two furanocoumarins in dietary supplements correlates with neither actual content nor CYP3A inhibitory activity

UNC Libraries(2020)10.17615/vs10-v861

N/A

0DataRank · unranked

0 citations

Karen M. VanderMolen, Nicholas H. Oberlies, Garrett R. Ainslie, Mary F. Paine

Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.01146-20

N/A

0DataRank · unranked

42 citations

Jessica M. Oda, Jessica Wagoner, Delaney Kirchmeier, Aidan O’Connor, Elizabeth A. Nelson +13 more

Modeling Pharmacokinetic Natural Product–Drug Interactions for Decision-Making: A NaPDI Center Recommended Approach

Pharmacological Reviews(2021)10.1124/pharmrev.120.000106

N/A

0DataRank · unranked

18 citations

Dandan Tian, John Clarke, Allan E. Rettie, Jashvant D. Unadkat, Kenneth E. Thummel +3 more

Hepatic organic anion transporting polypeptides mediate disposition of milk thistle flavonolignans and pharmacokinetic silymarin‐drug interactions

Phytotherapy Research(2021)10.1002/ptr.7049

N/A

0DataRank · unranked

11 citations

Michelle L. Montonye, Dandan Tian, Tarana Arman, Victoria O. Oyanna, Baron Bechtold +5 more

Comprehensive Predictions of Cytochrome P450 (P450)-Mediated In Vivo Cannabinoid-Drug Interactions Based on Reversible and Time-Dependent P450 Inhibition in Human Liver Microsomes

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000734

N/A

0DataRank · unranked

65 citations

Mary F. Paine, Jashvant D. Unadkat, Sumit Bansal

Evaluation of Cytochrome P450‐Mediated Cannabinoid‐Drug Interactions in Healthy Adult Participants

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.2973

N/A

0DataRank · unranked

66 citations

C. Austin Zamarripa, Tory R. Spindle, Elise M. Weerts, Kenneth E. Thummel, Ryan G. Vandrey +3 more

Developing a Knowledge Graph for Pharmacokinetic Natural Product-Drug Interactions

Journal of Biomedical Informatics(2023)10.1016/j.jbi.2023.104341

N/A

0DataRank · unranked

28 citations

Tiffany J. Callahan, Mary F. Paine, Sandra L. Kane‐Gill, Halil Kilicoglu, Marcin P. Joachimiak +2 more

Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom

Clinical Pharmacology & Therapeutics(2023)10.1002/cpt.2891

N/A

0DataRank · unranked

29 citations

James Nguyen, Deena L. Hadi, Matthew E. Layton, John R. White, Nadja B. Cech +5 more

Translating Kratom-Drug Interactions: From Bedside to Bench and Back

Drug Metabolism and Disposition(2023)10.1124/dmd.122.001005

N/A

0DataRank · unranked

24 citations

Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, Mary F. Paine +1 more

An Integrative Approach to Elucidate Mechanisms Underlying the Pharmacokinetic Goldenseal-Midazolam Interaction: Application of In Vitro Assays and Physiologically Based Pharmacokinetic Models to Understand Clinical Observations

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.123.001681

N/A

0DataRank · unranked

10 citations

Dandan Tian, Rakshit S. Tanna, Christopher M. Arian, Justina C. Calamia, Allan E. Rettie +3 more

Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice

Drug Metabolism and Disposition(2023)10.1124/dmd.123.001360

N/A

0DataRank · unranked

5 citations

Kenisha Yvette Garcia-Torres, Baron Bechtold, Katherine D. Lynch, M. Call, Miklós Horváth +7 more

Identification of Putative Novel Biomarkers of Organic Anion Transporter 1 and 3 for the Prediction of Transporter-Mediated Drug-Drug Interactions

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.245070

N/A

0DataRank · unranked

0 citations

Dilip Kumar Singh, Mary F. Paine, Bhagwat Prasad, Aarzoo Thakur

Managing Drug Interactions Involving the Over-the-Counter Opioid Loperamide through Physiologically Based Pharmacokinetic Modeling

Journal of Pharmacology and Experimental Therapeutics(2023)10.1124/jpet.122.266210

N/A

0DataRank · unranked

0 citations

Mengyao Li, Ping Zhao, Jean Dinh, Mary F. Paine, Zhu Zhou

Botanical-induced toxicity: Liver injury and botanical-drug interactions. A report on a society of Toxicology Annual Meeting symposium

Regulatory Toxicology and Pharmacology(2024)10.1016/j.yrtph.2024.105708

N/A

0DataRank · unranked

5 citations

R Philip Yeager, Constance A. Mitchell, Stephen Ferguson, Victor J. Navarro, Mary F. Paine +2 more

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

Pharmacology Research & Perspectives(2024)10.1002/prp2.70047

N/A

0DataRank · unranked

4 citations

Sandra L. Kane‐Gill, Xiaotong Li, Kojo Abanyie, Sanya B. Taneja, Susan Egbert +3 more

Part 1: Evaluation of Pediatric Cannabis–Drug Interaction Reports

Pharmacology Research & Perspectives(2024)10.1002/prp2.70046

N/A

0DataRank · unranked

3 citations

Sandra L. Kane‐Gill, Xiaotong Li, Kojo Abanyie, Sanya B. Taneja, Susan Egbert +3 more

Impact of Drug-Mediated Inhibition of Intestinal Transporters on Nutrient and Endogenous Substrate Disposition…an Afterthought?

Pharmaceutics(2024)10.3390/pharmaceutics16040447

N/A

0DataRank · unranked

2 citations

Andrew S. Engley, Mary F. Paine, Jason A. Sprowl, Kshitee Kharve

Physiologically Based Pharmacokinetic Modeling of Cannabidiol, Delta‐9‐Tetrahydrocannabinol, and Their Metabolites in Healthy Adults After Administration by Multiple Routes

Clinical and Translational Science(2025)10.1111/cts.70119

N/A

0DataRank · unranked

10 citations

Tao Zhang, Jean Dinh, Mary F. Paine, Zhu Zhou, Lixuan Qian

A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103597

N/A

0DataRank · unranked

2 citations

Eimear T O'Mahony, Preston K. Manwill, Tyler N. Graf, Nicholas H. Oberlies, Nadja B. Cech +6 more

From discovery to translation: Endogenous substrates of OAT1 and OAT3 as clinical biomarkers for renal secretory function

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.05.636675

N/A

0DataRank · unranked

0 citations

Dilip Kumar Singh, Katherine D. Hart, Emese Kis, Zsuzsanna Gáborik, Travis T. Denton +4 more

United States Pharmacopeia (USP) comprehensive review of the hepatotoxicity of green tea extracts

Toxicology Reports(2020)10.1016/j.toxrep.2020.02.008

N/A

0DataRank · unranked

161 citations

Amy L. Roe, Cynthia V. Rider, Herbert L. Bonkovsky, Gabriel I. Giancaspro, Victor J. Navarro +21 more

Identification and validation of selective endogenous substrates of organic anion transporter 1 (OAT1) versus OAT3 using metabolomics and in-vitro mechanistic studies

Drug Metabolism and Pharmacokinetics(2025)10.1016/j.dmpk.2025.101454

N/A

0DataRank · unranked

0 citations

Dilip Kumar Singh, Katherine D. Lynch, Emese Kis, Zsuzsanna Gáborik, John Clarke +3 more

Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions

Scientific Reports(2020)10.1038/s41598-020-76119-w

N/A

0DataRank · unranked

129 citations

Joshua J. Kellogg, E. Diane Wallace, Manead Khin, Laura Flores‐Bocanegra, Rakshit S. Tanna +8 more

“Natural” is not synonymous with “Safe”: Toxicity of natural products alone and in combination with pharmaceutical agents

Regulatory Toxicology and Pharmacology(2020)10.1016/j.yrtph.2020.104642

N/A

0DataRank · unranked

95 citations

Donna L. Mendrick, Mary F. Paine, Amy L. Roe, Catherine K. Yeung, Tyler E. Gaston

Mary F. Paine

Indexed papers

Top data-sharing exemplar

Papers