T.M. Penning

Translational Therapeutics (United States)

MedicineAgricultural and Biological SciencesVeterinaryBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.522Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Aldo-keto reductase (AKR) superfamily website and database: An update

Chemico-Biological Interactions(2024)10.1016/j.cbi.2024.111111

Top 37%

0.522DataRank

Top 37%15 citations

Jaehyun Joo, Nisha Narayanan, Anisha Tehim, Blanca E. Himes, T.M. Penning +1 more

Papers

Driven by 30 papers — median percentile 63. Top paper: “Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer”.

Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

Journal of Biological Chemistry(2020)10.1074/jbc.rev120.012411

N/A

0.529DataRank · unranked

33 citations

Ian A. Blair, Gregory Van Duyne, Vincent J. Hilser, Vera Y. Moiseenkova‐Bell, Stephen R. Plymate +4 more

Aldo-keto reductase (AKR) superfamily website and database: An update

Chemico-Biological Interactions(2024)10.1016/j.cbi.2024.111111

Top 37%

0.522DataRank

Top 37%15 citations

Jaehyun Joo, Nisha Narayanan, Anisha Tehim, Blanca E. Himes, T.M. Penning +1 more

Geographic Differences in Lung Cancer Incidence: A Study of a Major Metropolitan Area within Southeastern Pennsylvania

International Journal of Environmental Research and Public Health(2020)10.3390/ijerph17249498

N/A

0.483DataRank · unranked

24 citations

Thomas P. McKeon, Vicky Tam, Anil Vachani, T.M. Penning, Wei‐Ting Hwang +1 more

Insulin-Induced AKR1C3 Induces Fatty Acid Synthase in a Model of Human PCOS Adipocytes

Endocrinology(2023)10.1210/endocr/bqad033

N/A

0.457DataRank · unranked

20 citations

T.M. Penning, Ryan D. Paulukinas

Peripheral blood leukocyte mitochondrial DNA content and risk of lung cancer

Translational Lung Cancer Research(2022)10.21037/tlcr-21-979

N/A

0.292DataRank · unranked

6 citations

Nandita Mitra, T.M. Penning, Alexander S. Whitehead, Anil Vachani, Gregory T. Kennedy

Air pollution and lung cancer survival in Pennsylvania

Lung Cancer(2022)10.1016/j.lungcan.2022.06.004

N/A

0DataRank · unranked

39 citations

Anil Vachani, T.M. Penning, Wei‐Ting Hwang, Thomas P. McKeon

Reconstitution of human adrenocortical specification and steroidogenesis using induced pluripotent stem cells

Developmental Cell(2022)10.1016/j.devcel.2022.10.010

N/A

0DataRank · unranked

28 citations

Keren Cheng, Michinori Mayama, Yasunari Seita, Andrea J. Detlefsen, Clementina Mesaros +7 more

Automating Predictive Toxicology Using ComptoxAI

Chemical Research in Toxicology(2022)10.1021/acs.chemrestox.2c00074

N/A

0DataRank · unranked

20 citations

Yun Hao, Jason H. Moore, T.M. Penning, Joseph D. Romano

Characterization of the major single nucleotide polymorphic variants of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase)

The Journal of Steroid Biochemistry and Molecular Biology(2022)10.1016/j.jsbmb.2022.106121

N/A

0DataRank · unranked

10 citations

Phumvadee Wangtrakuldee, T.M. Penning, Andrea J. Detlefsen

Identification of spatio-temporal clusters of lung cancer cases in Pennsylvania, USA: 2010–2017

BMC Cancer(2022)10.1186/s12885-022-09652-8

N/A

0DataRank · unranked

10 citations

Tara McWilliams, Thomas P. McKeon, T.M. Penning, Wei‐Ting Hwang, Nuria Camiña

Germline Mutations in Steroid Metabolizing Enzymes: A Focus on Steroid Transforming Aldo-Keto Reductases

International Journal of Molecular Sciences(2023)10.3390/ijms24031873

N/A

0DataRank · unranked

27 citations

Ryan D. Paulukinas, T.M. Penning, Andrea J. Detlefsen

Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1-Nitropyrene via Nitroreduction in Human Lung Cells

Chemical Research in Toxicology(2023)10.1021/acs.chemrestox.2c00337

N/A

0DataRank · unranked

9 citations

T.M. Penning, Anthony L. Su

AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol

Cancer Research Communications(2023)10.1158/2767-9764.crc-23-0235

N/A

0DataRank · unranked

11 citations

Clementina Mesaros, Ling Duan, T.M. Penning, Andrea J. Detlefsen

Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model

Journal of Medicinal Chemistry(2023)10.1021/acs.jmedchem.3c00732

N/A

0DataRank · unranked

10 citations

Sravan K. Jonnalagadda, Ahmed Morsy, Ling Duan, Yashpal S. Chhonker, Daryl J. Murry +3 more

Association of multi-criteria derived air toxics hazard score with lung cancer incidence in a major metropolitan area

Frontiers in Public Health(2023)10.3389/fpubh.2023.1002597

N/A

0DataRank · unranked

8 citations

Tara McWilliams, Thomas P. McKeon, Anil Vachani, T.M. Penning, Wei‐Ting Hwang +1 more

Letter to the Editor From Penning and Detlefsen “Hydroxyeicosatetraenoic Acid Controls Androgen Reduction in Diverse Types of Human Epithelial Cells”

Endocrinology(2023)10.1210/endocr/bqad052

N/A

0DataRank · unranked

1 citations

Andrea J. Detlefsen, T.M. Penning

5β-Dihydrosteroids: Formation and Properties

International Journal of Molecular Sciences(2024)10.3390/ijms25168857

N/A

0DataRank · unranked

14 citations

Douglas F. Covey, T.M. Penning

Discovery of an Aldo-Keto reductase 1C3 (AKR1C3) degrader

Communications Chemistry(2024)10.1038/s42004-024-01177-4

N/A

0DataRank · unranked

13 citations

Shirisha Jonnalagadda, Alfie M. Case, Maddeboina Krishnaiah, Sravan K. Jonnalagadda, Louise F. Dow +4 more

A long and winding road: culture change on data sharing in exposomics

Exposome(2024)10.1093/exposome/osae004

N/A

0DataRank · unranked

6 citations

Konstantinos C. Makris, Pantelis Natsiavas, Timothy R. Fennell, Blake R. Rushing, Ander Wilson +90 more

Substrate specificity and kinetic mechanism of 3β-hydroxy- Δ 5-C27-steroid oxidoreductase

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107945

N/A

0DataRank · unranked

4 citations

Austin Vogt, T.M. Penning, Ronen Marmorstein, Sarah M. Gardner

Specific and potent inhibition of steroid hormone pre-receptor regulator AKR1C2 by perfluorooctanoic acid: Implications for androgen metabolism

The Journal of Steroid Biochemistry and Molecular Biology(2024)10.1016/j.jsbmb.2024.106641

N/A

0DataRank · unranked

7 citations

Anna Chung, Kim A. Sharp, T.M. Penning, Andrea Andress Huacachino

Coumarin‐Based Aldo‐Keto Reductase Family 1C (AKR1C) 2 and 3 Inhibitors

ChemMedChem(2024)10.1002/cmdc.202400081

N/A

0DataRank · unranked

4 citations

Ling Duan, Louise F. Dow, Geetha P. Boligala, Elizabeth A. Kosmacek, Kristyn McCoy +8 more

Alzheimer’s disease neuropathologic change mediates the relationship between ambient air pollution and dementia severity

medRxiv(2024)10.1101/2024.07.18.24310646

N/A

0DataRank · unranked

1 citations

Kaitlin Blam, Holly Elser, Sharon X. Xie, Vivianna M. Van Deerlin, T.M. Penning +8 more

Role of Human Aldo-Keto Reductases and Nuclear Factor Erythroid 2-Related Factor 2 in the Metabolic Activation of 1,8-Dinitropyrene and Its Metabolite 1-Amino-8-nitropyrene via Nitroreduction in Human Lung Cells

Chemical Research in Toxicology(2025)10.1021/acs.chemrestox.5c00101

N/A

0DataRank · unranked

2 citations

Cátia F. Marques, Jacek Krzeminski, Karam El‐Bayoumy, T.M. Penning, Anthony L. Su

Metabolic activation of flunitrazepam via nitroreduction mediated by aldo-keto reductase 1C3

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100142

N/A

0DataRank · unranked

1 citations

Maya Narang, Kim A. Sharp, T.M. Penning, Cátia F. Marques

Radioactive Tracing of Testosterone Reveals Minimal Formation of 5α-DHT in SGBS Cells and Human Primary Adipocytes

Journal of the Endocrine Society(2025)10.1210/jendso/bvaf087

N/A

0DataRank · unranked

1 citations

Cátia F. Marques, Clementina Mesaros, T.M. Penning, Andrea Andress Huacachino

Aldo-Keto Reductases and Cancer Drug Resistance

Pharmacological Reviews(2021)10.1124/pharmrev.120.000122

N/A

0DataRank · unranked

139 citations

Sravan K. Jonnalagadda, Paul C. Trippier, Tea Lanišnik Rižner, T.M. Penning

Genetic and epigenetic regulation of the NRF2-KEAP1 pathway in human lung cancer

British Journal of Cancer(2021)10.1038/s41416-021-01642-0

N/A

0DataRank · unranked

44 citations

T.M. Penning, Nuria Camiña

Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: Mechanism for high prostate androgen in African American men

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.09.467567

N/A

0DataRank · unranked

1 citations

Kirsten D. Krieger, Candice Loitz, Lillian M. Perez, Zachary Richards, Yves Helou +11 more

Conversion of Classical and 11-Oxygenated Androgens by Insulin-Induced AKR1C3 in a Model of Human PCOS Adipocytes

Endocrinology(2022)10.1210/endocr/bqac068

N/A

0DataRank · unranked

61 citations

Clementina Mesaros, T.M. Penning, Ryan D. Paulukinas

T.M. Penning

Indexed papers

Top data-sharing exemplar

Papers