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Metabolic activation of flunitrazepam via nitroreduction mediated by aldo-keto reductase 1C3

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100142Source: DataRank Database

Metabolic activation of flunitrazepam via nitroreduction mediated by aldo-keto reductase 1C3 is a research paper published in Drug Metabolism and Disposition (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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Enrichment:Funding (8 grants)Impact (FWCI 0.58)OA: greenTopics (23)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Maya Narang ORCID,Kim A. Sharp ORCID,T.M. Penning ORCID,Cátia F. Marques ORCID

Live enrichment

PubMed:40885108 PMC:PMC12562546 OpenAlex:https://openalex.org/W4413053280

National Institute of Environmental Health Sciences

Grant: R01-ES029294

National Institute of Environmental Health Sciences

Grant: P30-ES013508

National Institutes of Health

Grant: S10-OD023592

American Cancer Society

Grant: PF-24-1291669-01-CDP

NIEHS NIH HHS

Grant: P30 ES013508

National Institutes of Health Office of Research Infrastructure Programs

Grant: S10OD023592

NIEHS NIH HHS

Grant: R01 ES029294

Kansas Academy of Science

FWCI

0.58

Citation Percentile

0.7%

Citation Trend

2026

greenLicense: cc-by-nc

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12562546

publisherhttps://api.elsevier.com/content/article/PII:S0090955625091512?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955625091512?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.dmd.2025.100142

Fields of Study

Aldose Reductase and TaurineMetabolism and Genetic DisordersPharmacogenetics and Drug Metabolism

MeSH Terms

Aldo-Keto Reductase Family 1 Member C3FlunitrazepamHumansHydroxyprostaglandin DehydrogenasesOxidation-Reduction20-Hydroxysteroid Dehydrogenases3-Hydroxysteroid Dehydrogenases3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)Molecular Docking SimulationActivation, Metabolic

Keywords

Aldo-keto reductaseChemistryReductaseEnzymeFlunitrazepamBiochemistryHepatoma cellsMass spectrometryDrug metabolismAldo-keto Reductases

Sustainable Development Goals

SDG 0: Clean water and sanitation

Metabolic activation of flunitrazepam via nitroreduction mediated by aldo-keto reductase 1C3

FAIR Checklist

Authors (4)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)