Lei S. Qi

Also affiliated with Nantong University, Shanghai Ninth People's Hospital, Chan Zuckerberg Initiative (United States), National Clinical Research, Stanford Medicine, Stanford University

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 51 papers. Top paper: “High-content CRISPR screening”.

High-content CRISPR screening

Nature Reviews Methods Primers(2022)10.1038/s43586-022-00098-7

N/A

6.0DataRank · unranked

255 citations

Paul Datlinger, Florence M. Chardon, Matthew A. Coelho, Matthew B. Dong, Keith A. Lawson +15 more

A benchmark of algorithms for the analysis of pooled CRISPR screens

Genome biology(2020)10.1186/s13059-020-01972-x

N/A

2.5DataRank · unranked

87 citations

Timothy Daley, Xueqiu Lin, James Zou, Lei S. Qi, Sunil Bodapati

Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1914906117

N/A

2.5DataRank · unranked

93 citations

Yi Feng, Josquin Foiret, Azadeh Kheirolomoom, Hua Zhang, Elizabeth S. Ingham +16 more

The use of new CRISPR tools in cardiovascular research and medicine

Nature Reviews Cardiology(2022)10.1038/s41569-021-00669-3

N/A

0.626DataRank · unranked

64 citations

Chunying Liu, Lei S. Qi, Joseph C. Wu, Masataka Nishiga

SARS-CoV-2 escapes direct NK cell killing through Nsp1-mediated downregulation of ligands for NKG2D

Cell Reports(2022)10.1016/j.celrep.2022.111892

N/A

0.568DataRank · unranked

43 citations

Michelle Leong, Arjun Rustagi, Aimee Beck, Leiping Zeng, Susan Holmes +3 more

Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strength

Cell stem cell(2025)10.1016/j.stem.2025.05.012

N/A

0.499DataRank · unranked

26 citations

Adelaida R. Palla, Andrew Tri Van Ho, Daniel C.L. Robinson, Meenakshi Ravichandran, Glenn J. Markov +14 more

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.12.540558

N/A

0.464DataRank · unranked

21 citations

Mike V. Van, Aradhana Aradhana, Nicole DelRosso, David Yao, Xiaoshu Xu +12 more

Integrin α6β4 requires plectin and vimentin for adhesion complex distribution and invasive growth

Journal of Cell Science(2021)10.1242/jcs.258471

N/A

0.385DataRank · unranked

12 citations

Teresa Knifley, Min Chen, Kathleen L. O’Connor, Lei S. Qi

CRISPR tools for T cells: targeting the genome, epigenome, and transcriptome

Trends in cancer(2025)10.1016/j.trecan.2025.08.001

N/A

0.241DataRank · unranked

4 citations

Lei S. Qi, Tassilo L A Wachsmann

Interrogation of the Dynamic Properties of Higher-Order Heterochromatin Using CRISPR/dCas9

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.06.447300

N/A

0.208DataRank · unranked

3 citations

Mengting Han, Stephen Shang, Haifeng Wang, Lei S. Qi, Yuchen Gao

CRISPR-Cas13d-Mediated Targeting of a Context-Specific Essential Gene Enables Selective Elimination of Uveal Melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.21.671629

N/A

0.104DataRank · unranked

1 citations

Lucas Sosnick, Yi-Tong Ma, Sopida Pimcharoen, Atip Lawanprasert, Niren Murthy +3 more

Enhanced Cas12a multi-gene regulation using a CRISPR array separator

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.27.428408

N/A

0DataRank · unranked

2 citations

Antonio Rios, Lingling Wu, Lei S. Qi, Jens P. Magnusson

Quantification of durable CRISPR-based gene silencing activity

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.31.436355

N/A

0DataRank · unranked

0 citations

Alexis E. Ivec, Yuchen Gao, Lei S. Qi, Muneaki Nakamura

Advances in CRISPR therapeutics

Nature Reviews Nephrology(2022)10.1038/s41581-022-00636-2

N/A

0DataRank · unranked

174 citations

Xinyi Chen, Paul B. Finn, Lei S. Qi, Michael Chavez

Broad-spectrum CRISPR-mediated inhibition of SARS-CoV-2 variants and endemic coronaviruses in vitro

Nature Communications(2022)10.1038/s41467-022-30546-7

N/A

0DataRank · unranked

53 citations

Yanxia Liu, Xammy Nguyenla, Timothy R. Abbott, Mengting Han, Yan‐Yu Zhu +23 more

Multi-color super-resolution imaging to study human coronavirus RNA during cellular infection

Cell Reports Methods(2022)10.1016/j.crmeth.2022.100170

N/A

0DataRank · unranked

25 citations

Mengting Han, Anish R. Roy, Haifeng Wang, Leonhard Möckl, Leiping Zeng +3 more

Hormone sensitive lipase ablation promotes bone regeneration

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease(2022)10.1016/j.bbadis.2022.166449

N/A

0DataRank · unranked

1 citations

Chris Still, Lina Han, Pinglin Yang, Jia Chen, Michael N. Wosczyna +10 more

Cas9-Mediated Knockout of Ndrg2 Enhances the Regenerative Potential of Dendritic Cells for Wound Healing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.03.14.484360

N/A

0DataRank · unranked

2 citations

Dehua Zhao, Kellen Chen, Artem A. Trotsyuk, Clark A. Bonham, Katharina S. Fischer +16 more

Statins improve endothelial function via suppression of epigenetic-driven EndMT

Nature Cardiovascular Research(2023)10.1038/s44161-023-00267-1

N/A

0DataRank · unranked

82 citations

Mengcheng Shen, Wilson Lek Wen Tan, Ian Y. Chen, Yu Liu, Xuan Yu +11 more

Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing

Nature Communications(2023)10.1038/s41467-023-40519-z

N/A

0DataRank · unranked

41 citations

Dehua Zhao, Dharshan Sivaraj, Artem A. Trotsyuk, Clark A. Bonham, Katharina S. Fischer +17 more

Reversing the Central Dogma: RNA-guided control of DNA in epigenetics and genome editing

Molecular Cell(2023)10.1016/j.molcel.2023.01.010

N/A

0DataRank · unranked

29 citations

Lei S. Qi, Howard Y. Chang

Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus

Nature Biomedical Engineering(2023)10.1038/s41551-023-01037-x

N/A

0DataRank · unranked

28 citations

Draven A. Rane, Xinyi Chen, Lei S. Qi, Michael Chavez

Shuffling the yeast genome using CRISPR/Cas9-generated DSBs that target the transposable Ty1 elements

PLoS Genetics(2023)10.1371/journal.pgen.1010590

N/A

0DataRank · unranked

23 citations

Yang Sui, Xing-Xing Tang, Ryan J. McGinty, Xiao-Zhuan Liang, Margaret Dominska +5 more

Sonogenetic control of multiplexed genome regulation and base editing

Nature Communications(2023)10.1038/s41467-023-42249-8

N/A

0DataRank · unranked

22 citations

Josquin Foiret, Yinglin Situ, Nisi Zhang, Aris J. Kare, Bo Wu +4 more

Building smart CAR T cell therapies: The path to overcome current challenges

Cancer Cell(2023)10.1016/j.ccell.2023.08.011

N/A

0DataRank · unranked

14 citations

Sarah Warren, Violena Pietrobon, Markus Maeurer, Lei S. Qi, Timothy K. Lu +5 more

Drug-Mediated Control of Receptor Valency Enhances Immune Cell Potency

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.04.522664

N/A

0DataRank · unranked

2 citations

Michael Chavez, Xinyi Chen, Haifeng Wang, Draven A. Rane, Jitendra Gurjar +2 more

A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells

Cell(2024)10.1016/j.cell.2024.01.035

N/A

0DataRank · unranked

115 citations

Elena Sotillo, Jeremy Bjelajac, Xingyu Chen, Meena Malipatlolla, Justin A. Guerrero +7 more

CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity

Cell stem cell(2024)10.1016/j.stem.2024.10.007

N/A

0DataRank · unranked

40 citations

Mengcheng Shen, Yanxia Liu, Amit Manhas, Rui Zhao, Mao Zhang +15 more

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Nature Biotechnology(2024)10.1038/s41587-024-02442-6

N/A

0DataRank · unranked

39 citations

Mike V. Van, Aradhana, Nicole DelRosso, Haihong Ye, David Yao +21 more

Nanoscale cellular organization of viral RNA and proteins in SARS-CoV-2 replication organelles

Nature Communications(2024)10.1038/s41467-024-48991-x

N/A

0DataRank · unranked

30 citations

Mengting Han, Yan‐Yu Zhu, Ashwin Balaji, Anish R. Roy, Andrew E. S. Barentine +5 more

A frugal CRISPR kit for equitable and accessible education in gene editing and synthetic biology

Nature Communications(2024)10.1038/s41467-024-50767-2

N/A

0DataRank · unranked

22 citations

Matthew B. Lau, William Ma, Aidan Shen, Brenda Wang, Sa Cai +4 more

The realization of CRISPR gene therapy

Nature Chemical Biology(2024)10.1038/s41589-024-01645-x

N/A

0DataRank · unranked

10 citations

Lei S. Qi, Yitong Ma

Precision Transcriptome Editing

ACS Synthetic Biology(2024)10.1021/acssynbio.4c00183

N/A

0DataRank · unranked

3 citations

Lei S. Qi, Xingyu Chen

Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.05.583597

N/A

0DataRank · unranked

0 citations

Sayaka Kozuki, Clara Han, Benjamin R. Topacio, Abolfazl Zargari, Seung‐Ho Lee +5 more

High-resolution dynamic imaging of chromatin DNA communication using Oligo-LiveFISH

Cell(2025)10.1016/j.cell.2025.03.032

N/A

0DataRank · unranked

28 citations

Ashwin Balaji, Mengting Han, Leonid Andronov, Anish R. Roy, Zheng Wei +12 more

Transient non-integrative expression of nuclear reprogramming factors promotes multifaceted amelioration of aging in human cells

Nature Communications(2020)10.1038/s41467-020-15174-3

N/A

0DataRank · unranked

315 citations

Marco Quarta, Shravani Mukherjee, Alex Colville, Patrick Paine, Linda Doan +8 more

Large-scale CRISPR screening in primary human 3D gastric organoids enables comprehensive dissection of gene-drug interactions

Nature Communications(2025)10.1038/s41467-025-62818-3

N/A

0DataRank · unranked

21 citations

Hudson T. Horn, Mo-Fan Huang, Wei-Chieh Yu, C.S. Young, Qing Liu +10 more

Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

Cell stem cell(2025)10.1016/j.stem.2025.02.015

N/A

0DataRank · unranked

15 citations

Sayaka Kozuki, Clara Han, Benjamin R. Topacio, Seung‐Ho Lee, Lily Nixon +6 more

Identification of replicative aging and inflammatory aging signatures via whole-genome CRISPRi screens

Genome biology(2025)10.1186/s13059-025-03683-7

N/A

0DataRank · unranked

5 citations

Xiang Zhu, Yanxia Liu, Dehua Zhao, Bing Yu, Zheng Wei +3 more

CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice

Science Translational Medicine(2025)10.1126/scitranslmed.adq3551

N/A

0DataRank · unranked

3 citations

Xiying Wang, Jie Pan, Danish Khan, Sopida Pimcharoen, Yong‐Jie Zhang +7 more

Programmable control of spatial transcriptome in live cells and neurons

Nature(2025)10.1038/s41586-025-09020-z

N/A

0DataRank · unranked

24 citations

Maylin L. Fu, Yan‐Yu Zhu, Alexander A. Choi, Emmy Li, Jon Bezney +5 more

Therapeutic genome editing in cardiovascular diseases

Advanced Drug Delivery Reviews(2020)10.1016/j.addr.2020.02.003

N/A

0DataRank · unranked

41 citations

Lei S. Qi, Joseph C. Wu, Masataka Nishiga

Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.1922472117

N/A

0DataRank · unranked

32 citations

Lei S. Qi, Ke Zhang, Natalie Saini, Leszek J. Klimczak, Cynthia J. Sakofsky +4 more

CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes

Journal of Molecular and Cellular Cardiology(2020)10.1016/j.yjmcc.2020.06.004

N/A

0DataRank · unranked

28 citations

Huimei Zang, Weiwei Wu, Prakash Nagarkatti, Mitzi Nagarkatti, Qinghang Liu +4 more

Systematic genome-wide querying of coding and non-coding functional elements in E. coli using CRISPRi

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.04.975888

N/A

0DataRank · unranked

25 citations

Esteban Toro, Honglei Liu, Xiaowo Wang, Lei S. Qi, Adam P. Arkin +1 more

CRISPR technologies for precise epigenome editing

Nature Cell Biology(2021)10.1038/s41556-020-00620-7

N/A

0DataRank · unranked

447 citations

Yuchen Gao, Antonia A. Dominguez, Lei S. Qi, Muneaki Nakamura

Engineering 3D genome organization

Nature Reviews Genetics(2021)10.1038/s41576-020-00325-5

N/A

0DataRank · unranked

69 citations

Mengting Han, Lei S. Qi, Haifeng Wang

CRISPR-based genome editing in primary human pancreatic islet cells

Nature Communications(2021)10.1038/s41467-021-22651-w

N/A

0DataRank · unranked

53 citations

Xiao-Qing Dai, Jonathan Y. Lam, Xueying Gu, M. Friedländer, Krissie Tellez +11 more

Enhanced Cas12a multi-gene regulation using a CRISPR array separator

eLife(2021)10.7554/elife.66406

N/A

0DataRank · unranked

46 citations

Antonio Rios, Lingling Wu, Lei S. Qi, Jens P. Magnusson

Durable CRISPR-Based Epigenetic Silencing

BioDesign Research(2021)10.34133/2021/9815820

N/A

0DataRank · unranked

27 citations

Alexis E. Ivec, Yuchen Gao, Lei S. Qi, Muneaki Nakamura

Multi-color super-resolution imaging to study human coronavirus RNA during cellular infection

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.09.447760

N/A

0DataRank · unranked

3 citations

Mengting Han, Anish R. Roy, Haifeng Wang, Leonhard Möckl, Leiping Zeng +3 more