Paul S. Mischel

Also affiliated with Stanford University

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data from Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

(2023)10.1158/1078-0432.c.6531387.v1

Top 100%

0DataRank

Top 100%0 citations

Nam Nguyen, Jens Luebeck, Laurel Ball, Andrey Finegersh, Shuling Ren +12 more

Papers

Driven by 52 papers — median percentile 0. Top paper: “Single-cell analysis tools for drug discovery and development”.

Single-cell analysis tools for drug discovery and development

Nature Reviews Drug Discovery(2016)10.1038/nrd.2015.16

N/A

10.9DataRank · unranked

486 citations

Antoni Ribas, Paul S. Mischel, James R. Heath

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Nature Genetics(2020)10.1038/s41588-020-0678-2

N/A

9.9DataRank · unranked

641 citations

Nam Nguyen, Kristen M. Turner, Sihan Wu, Amit D. Gujar, Jens Luebeck +15 more

AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

Nature Communications(2020)10.1038/s41467-020-18099-z

N/A

2.3DataRank · unranked

98 citations

Ceyda Çoruh, Siavash R. Dehkordi, Joshua T. Lange, Kristen M. Turner, Viraj Deshpande +7 more

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

Proceedings of the National Academy of Sciences(2007)10.1073/pnas.0710052104

N/A

1.0DataRank · unranked

1085 citations

Gad Getz, Leia Nghiemphu, Jordi Barretina, Teli Hsueh, David Linhart +31 more

The evolutionary dynamics of extrachromosomal DNA in human cancers

Nature Genetics(2022)10.1038/s41588-022-01177-x

N/A

0.795DataRank · unranked

200 citations

John C. Rose, Celine Chen, Yuriy Pichugin, Liangqi Xie, Jun Tang +17 more

Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2210991120

N/A

0.788DataRank · unranked

28 citations

Anugraha Raman, Sebastian Preissl, Jianfang Ning, Shaoping Wu, Tomoyuki Koga +22 more

CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing

Genome Research(2024)10.1101/gr.279131.124

N/A

0.768DataRank · unranked

34 citations

Matthew G. Jones, Jens Luebeck, Xinxin Bu, Hyerim Yi, King L. Hung +6 more

Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Nature Genetics(2023)10.1038/s41588-023-01551-3

N/A

0.631DataRank · unranked

66 citations

Jens Luebeck, Sunita Sridhar, Ivy Tsz-Lo Wong, Deobrat Dixit, Shanqing Wang +43 more

Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.11.447968

N/A

0.425DataRank · unranked

16 citations

Celine Chen, Yuriy Pichugin, Liangqi Xie, Jun Tang, King L. Hung +14 more

Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.12.571349

N/A

0.300DataRank · unranked

4 citations

Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad +23 more

Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer

Metabolites(2021)10.3390/metabo11040216

N/A

0DataRank · unranked

30 citations

Kenta Masui, Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata, Mio Harachi

The landscape of extrachromosomal circular DNA in medulloblastoma

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.18.464907

N/A

0DataRank · unranked

13 citations

Jens Luebeck, Sameena Wani, Ashutosh Tiwari, Meghana S. Pagadala, Shanqing Wang +26 more

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.28.470285

N/A

0DataRank · unranked

13 citations

Jens Luebeck, Siavash R. Dehkordi, Ceyda Çoruh, Julie A. Law, William J. Greenleaf +4 more

Comprehensive analysis of clustered mutations in cancer reveals recurrent APOBEC3 mutagenesis of ecDNA

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.27.445689

N/A

0DataRank · unranked

4 citations

Jens Luebeck, Mia Petljak, Vineet Bafna, Paul S. Mischel, Reuben S. Harris +2 more

Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA

Nature(2022)10.1038/s41586-022-04398-6

N/A

0DataRank · unranked

168 citations

Jens Luebeck, Mia Petljak, Azhar Khandekar, Mark Barnes, Tongwu Zhang +8 more

Targeted profiling of human extrachromosomal DNA by CRISPR-CATCH

Nature Genetics(2022)10.1038/s41588-022-01190-0

N/A

0DataRank · unranked

125 citations

Jens Luebeck, Siavash R. Dehkordi, Caterina I. Colón, Rui Li, Ivy Tsz-Lo Wong +21 more

Gene regulation on extrachromosomal DNA

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00806-7

N/A

0DataRank · unranked

54 citations

Paul S. Mischel, Howard Y. Chang, King L. Hung

Extrachromosomal DNA in Cancer

Annual Review of Genomics and Human Genetics(2022)10.1146/annurev-genom-120821-100535

N/A

0DataRank · unranked

50 citations

Paul S. Mischel, Vineet Bafna

Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation

Cell Reports(2022)10.1016/j.celrep.2022.111630

N/A

0DataRank · unranked

39 citations

Patrick C. Fiaux, Kai Zhang, Bin Li, Naoki Kubo, Shan Jiang +9 more

The metabolomic landscape plays a critical role in glioma oncogenesis

Cancer Science(2022)10.1111/cas.15325

N/A

0DataRank · unranked

23 citations

Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata, Kenta Masui

Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus

Nature(2023)10.1038/s41586-023-05937-5

N/A

0DataRank · unranked

191 citations

Alvin Wei Tian Ng, Patricia C. Galipeau, Xiaohong Li, Carissa A. Sanchez, Annalise Katz‐Summercorn +15 more

Epigenetic dysregulation from chromosomal transit in micronuclei

Nature(2023)10.1038/s41586-023-06084-7

N/A

0DataRank · unranked

118 citations

Duaa H. Al-Rawi, Bhargavi Dameracharla, Ramya Raviram, Bailey S.C.L. Jones, Stephanie Stransky +27 more

Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors

eLife(2023)10.7554/elife.88895

N/A

0DataRank · unranked

29 citations

Se‐Young Jo, Jens Luebeck, Howard Y. Chang, Sihan Wu, Paul S. Mischel +2 more

A Cell Type Selective YM155 Prodrug Targets Receptor-Interacting Protein Kinase 2 to Induce Brain Cancer Cell Death

Journal of the American Chemical Society(2023)10.1021/jacs.2c11715

N/A

0DataRank · unranked

14 citations

Junfeng Bi, Francisco Martínez‐Peña, Ellis J. Curtis, Nathalia Gazaniga, Paul S. Mischel +2 more

Metabolic and epigenetic reprogramming in the pathogenesis of glioblastoma: Toward the establishment of “metabolism‐based pathology”

Pathology International(2023)10.1111/pin.13379

N/A

0DataRank · unranked

12 citations

Paul S. Mischel, Kenta Masui

Coordinated inheritance of extrachromosomal DNA species in human cancer cells

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.18.549597

N/A

0DataRank · unranked

6 citations

Matthew G. Jones, Ivy Tsz-Lo Wong, Joshua T. Lange, Jens Luebeck, Elisa Scanu +14 more

Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.24.537925

N/A

0DataRank · unranked

3 citations

Se‐Young Jo, Jens Luebeck, Howard Y. Chang, Sihan Wu, Paul S. Mischel +2 more

Disparate pathways for extrachromosomal DNA biogenesis and genomic DNA repair

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.22.563489

N/A

0DataRank · unranked

3 citations

Ivy Tsz-Lo Wong, Bence Dániel, Matthew G. Jones, Kathryn E. Yost, King L. Hung +4 more

Data from Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

(2023)10.1158/1078-0432.c.6531387.v1

Top 100%

0DataRank

Top 100%0 citations

Nam Nguyen, Jens Luebeck, Laurel Ball, Andrey Finegersh, Shuling Ren +12 more

Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses

Science(2024)10.1126/science.adi2396

N/A

0DataRank · unranked

34 citations

Saborni Chakraborty, Elsa Solà, Ray Fong, Vishnu Shankar, Fei Gao +11 more

DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01750-x

N/A

0DataRank · unranked

10 citations

Kenta Masui, Erika Shimizu, Kumiko Murakami, Hiromi Onizuka, Yoshihiro Muragaki +9 more

Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas

Annals of Oncology(2024)10.1016/j.annonc.2024.03.008

N/A

0DataRank · unranked

7 citations

Jens Luebeck, Andrew Rowan, Eva Grönroos, Valérie Barbe, Mark Fabian +6 more

Transcriptional immune suppression and up-regulation of double-stranded DNA damage and repair repertoires in ecDNA-containing tumors

eLife(2024)10.7554/elife.88895.3

N/A

0DataRank · unranked

4 citations

Se‐Young Jo, Jens Luebeck, Howard Y. Chang, Sihan Wu, Paul S. Mischel +2 more

CoRAL accurately resolves extrachromosomal DNA genome structures with long-read sequencing

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.15.580594

N/A

0DataRank · unranked

3 citations

Matthew G. Jones, Jens Luebeck, Xinxin Bu, Hyerim Yi, King L. Hung +6 more

Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.29.586681

N/A

0DataRank · unranked

2 citations

Natasha E. Weiser, Guiping Wang, Sudhir Chowdhry, Ellis J. Curtis, Yanding Zhao +20 more

Reviewer #2 (Public Review): Transcriptional immune suppression and upregulation of double stranded DNA damage and repair repertoires in ecDNA-containing tumors

(2024)10.7554/elife.88895.2.sa1

N/A

0DataRank · unranked

0 citations

Se‐Young Jo, Jens Luebeck, Howard Y. Chang, Sihan Wu, Paul S. Mischel +2 more

Oxidative stress is a shared characteristic of ME/CFS and Long COVID

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2426564122

N/A

0DataRank · unranked

23 citations

Julie Wilhelmy, Ellis J. Curtis, Basil Michael, Layla Cervantes, Vamsee Mallajosyula +9 more

Breakage fusion bridge cycles drive high oncogene number with moderate intratumoural heterogeneity

Nature Communications(2025)10.1038/s41467-025-56670-8

N/A

0DataRank · unranked

22 citations

Ivy Tsz-Lo Wong, Jing Ni, Jens Luebeck, Kaiyuan Zhu, Gino Prasad +25 more

Enhancer activation from transposable elements in extrachromosomal DNA

Nature Cell Biology(2025)10.1038/s41556-025-01788-6

N/A

0DataRank · unranked

13 citations

Sedona E. Murphy, Matthew G. Jones, Quanming Shi, Aarohi Bhargava-Shah, Christy Luong +14 more

Inhibition of human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer

Nature Communications(2025)10.1038/s41467-025-57447-9

N/A

0DataRank · unranked

11 citations

Jens Luebeck, Kaiyuan Zhu, Joshua T. Lange, Roman Šášik, Chad Phillips +13 more

Applying multilevel selection to understand cancer evolution and progression

PLoS Biology(2025)10.1371/journal.pbio.3003290

N/A

0DataRank · unranked

7 citations

Anaïs Lamoureux, Harley I. Richker, Gissel Marquez Alcaraz, Angelo Fortunato, Zachary Shaffer +6 more

Extrachromosomal DNA micronucleation constrains tumour fitness and improves patient survival

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.15.648906

N/A

0DataRank · unranked

5 citations

Robin Xu, Jun Tang, Aditi Gnanasekar, Alexander M. Herrmann, Ivy Tsz-Lo Wong +56 more

Genetic elements promote retention of extrachromosomal DNA in cancer cells

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.10.681495

N/A

0DataRank · unranked

1 citations

King L. Hung, Aditi Gnanasekar, Ivy Tsz-Lo Wong, Quanming Shi, Katerina Kraft +11 more

Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM

Molecular Cancer Research(2020)10.1158/1541-7786.mcr-20-0024

N/A

0DataRank · unranked

55 citations

Kenta Masui, Hiroaki Honda, Yoshihiro Muragaki, Takakazu Kawamata, Webster K. Cavenee +3 more

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

Nature Communications(2020)10.1038/s41467-020-14312-1

N/A

0DataRank · unranked

60 citations

Isaac A. Chaim, Jorge A. Benítez, Sebastian Markmiller, Alison D. Parisian, Robert F. Hevner +16 more

mTOR complex 2 is an integrator of cancer metabolism and epigenetics

Cancer Letters(2020)10.1016/j.canlet.2020.03.001

N/A

0DataRank · unranked

36 citations

Mio Harachi, Webster K. Cavenee, Paul S. Mischel, Noriyuki Shibata, Kenta Masui

What Is Extrachromosomal Circular DNA and What Does It Do?

Clinical Chemistry(2020)10.1093/clinchem/hvaa096

N/A

0DataRank · unranked

29 citations

Anindya Dutta, Anton G. Henssen, Y. M. Dennis Lo, Paul S. Mischel, Birgitte Regenberg +1 more

EcDNA hubs drive cooperative intermolecular oncogene expression

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.19.390278

N/A

0DataRank · unranked

15 citations

Kathryn E. Yost, Liangqi Xie, Sihan Wu, Joshua T. Lange, Connor V. Duffy +14 more

ecDNA hubs drive cooperative intermolecular oncogene expression

Nature(2021)10.1038/s41586-021-04116-8

N/A

0DataRank · unranked

344 citations

Kathryn E. Yost, Liangqi Xie, Quanming Shi, Konstantin Helmsauer, Jens Luebeck +29 more

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

Nature Communications(2021)10.1038/s41467-021-25529-z

N/A

0DataRank · unranked

61 citations

Jasmine H. Francis, Albert S. Agustinus, Ethan M. Earlie, Melody Di Bona, David H. Abramson +9 more

BAP1 methylation: a prognostic marker of uveal melanoma metastasis

npj Precision Oncology(2021)10.1038/s41698-021-00226-8

N/A

0DataRank · unranked

25 citations

Ellis J. Curtis, Michael H. Goldbaum, Paul S. Mischel, Mathieu F. Bakhoum

Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-21-2484

N/A

0DataRank · unranked

45 citations

Nam Nguyen, Jens Luebeck, Laurel Ball, Andrey Finegersh, Shuling Ren +12 more

Paul S. Mischel

Indexed papers

Top data-sharing exemplar

Papers