🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Joshua Chiou

Pfizer (United States)

ORCID: 0000-0002-4618-0647
MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile
9.6Author DataRank

Indexed papers

2in pilot corpus
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A single-cell atlas of chromatin accessibility in the human genome

Cell(2021)10.1016/j.cell.2021.10.024
Top 4%
4.8DataRank
Top 4%533 citations

James D. Hocker, Michael Miller, Xiaomeng Hou, Joshua Chiou, Olivier Poirion +7 more

Papers

Driven by 26 papers — median percentile 96. Top paper: “Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics”.

Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics

Nature Medicine(2021)10.1038/s41591-020-01227-z
N/A
8.2DataRank · unranked
378 citations

Malte D. Luecken, Gökcen Eraslan, Lisa Sikkema, Avinash Waghray, Graham Heimberg +95 more

A single-cell atlas of chromatin accessibility in the human genome

Cell(2021)10.1016/j.cell.2021.10.024
Top 4%
4.8DataRank
Top 4%533 citations

James D. Hocker, Michael Miller, Xiaomeng Hou, Joshua Chiou, Olivier Poirion +7 more

An atlas of dynamic chromatin landscapes in mouse fetal development

Nature(2020)10.1038/s41586-020-2093-3
Top 5%
4.8DataRank
Top 5%441 citations

Iros Barozzi, Yuan Zhao, Yanxiao Zhang, Hui Huang, Ah Young Lee +38 more

Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes

Nature Genetics(2023)10.1038/s41588-023-01397-9
N/A
1.9DataRank · unranked
82 citations

Joshua Chiou, Chun Zeng, Michael Miller, Ileana Matta, Jee Yun Han +16 more

Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

Nature(2021)10.1038/s41586-021-03552-w
N/A
0.929DataRank · unranked
487 citations

Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca Melton +11 more

Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development

eLife(2021)10.7554/elife.59067
N/A
0.889DataRank · unranked
27 citations

Allen Wang, Joshua Chiou, Joseph J. Lancman, Nichole Wetton, Samy Kefalopoulou +9 more

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

Cell Genomics(2022)10.1016/j.xgen.2022.100214
N/A
0.807DataRank · unranked
32 citations

Han Zhu, Mei-Lin Okino, Jian Yan, Ruth M. Elgamal, Naoki Nariai +18 more

Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk

Nature Genetics(2021)10.1038/s41588-021-00823-0
N/A
0.800DataRank · unranked
206 citations

Chun Zeng, Cheng Zhang, Jee Yun Han, Michael Schlichting, Michael Miller +15 more

Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors

Nature Communications(2021)10.1038/s41467-021-26950-0
N/A
0.631DataRank · unranked
66 citations

Allen Wang, Dieter K. Lam, Nicholas K. Vinckier, Konstantinos–Dionysios Alysandratos, David A. Roberts +10 more

Single-cell multiome and spatial profiling reveals pancreas cell type–specific gene regulatory programs of type 1 diabetes progression

Science Advances(2025)10.1126/sciadv.ady0080
N/A
0.459DataRank · unranked
19 citations

Sara Jiménez, Weston Elison, Luca Tucciarone, Abigail Howell, Gaowei Wang +18 more

Large-scale genetic association and single cell accessible chromatin mapping defines cell type-specific mechanisms of type 1 diabetes risk

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.13.426472
N/A
0.371DataRank · unranked
6 citations

Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Paola Benaglio +9 more

Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.13.637721
N/A
0.104DataRank · unranked
1 citations

Sara Jimenez, Weston Elison, Luca Tucciarone, Abigail Howell, Gaowei Wang +20 more

Circulating pancreatic enzyme levels are a causal biomarker of type 1 diabetes

medRxiv(2024)10.1101/2024.08.08.24311619
N/A
0DataRank · unranked
3 citations

Rebecca Melton, Joshua Chiou, Carolyn McGrail, Kyle J. Gaulton, Ruth M. Elgamal

Common DNA sequence variation influences 3-dimensional conformation of the human genome

UNC Libraries(2024)10.17615/kmnm-q097
N/A
0DataRank · unranked
0 citations

Tristin Liu, Bing Ren, Joshua Chiou, Yun Li, Ming Hu +8 more

Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits

Genome biology(2025)10.1186/s13059-025-03480-2
N/A
0DataRank · unranked
9 citations

Xianyong Yin, Brady Ryan, Joshua Chiou, Francesca Luca, Roger Piqué-Regi +8 more

An atlas of gene regulatory elements in adult mouse cerebrum

Nature(2021)10.1038/s41586-021-03604-1
N/A
0DataRank · unranked
208 citations

Sebastian Preissl, Xiaomeng Hou, Ziyang Zhang, Kai Zhang, Yunjiang Qiu +23 more

Cardiac cell type–specific gene regulatory programs and disease risk association

Science Advances(2021)10.1126/sciadv.abf1444
N/A
0DataRank · unranked
146 citations

Olivier Poirion, Fugui Zhu, Justin Buchanan, Kai Zhang, Joshua Chiou +13 more

Mutations and variants of ONECUT1 in diabetes

Nature Medicine(2021)10.1038/s41591-021-01502-7
N/A
0DataRank · unranked
58 citations

Sandra Heller, Ivan G. Costa, Valérie Senée, Markus Breunig, Zhijian Li +35 more

Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes

PLoS Genetics(2021)10.1371/journal.pgen.1009531
N/A
0DataRank · unranked
29 citations

Mei-Lin Okino, Paola Benaglio, Joshua Chiou, Elisha Beebe, Jose Andres Padilla +3 more

Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.29.466025
N/A
0DataRank · unranked
7 citations

Han Zhu, Mei-Lin Okino, Jian Yan, Ruth M. Elgamal, Naoki Nariai +15 more

Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Nature Genetics(2022)10.1038/s41588-022-01058-3
N/A
0DataRank · unranked
748 citations

Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng, Lauren E. Petty, Hidetoshi Kitajima +95 more

High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease

Diabetologia(2022)10.1007/s00125-022-05848-6
N/A
0DataRank · unranked
87 citations

Kenneth E. Westerman, Kirk Smith, Joshua Chiou, Joanne B. Cole, Timothy D. Majarian +9 more

The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

Nature Immunology(2023)10.1038/s41590-023-01529-7
N/A
0DataRank · unranked
87 citations

Bryan S. Yung, Farhoud Faraji, Robert Saddawi‐Konefka, Zhiyong Wang, Alexander T. Wenzel +16 more

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

Journal of Clinical Investigation(2023)10.1172/jci165208
N/A
0DataRank · unranked
25 citations

Fenfen Liu, Austin R. Harrington, Johanna Y. Fleischman, Martina Wallace, Francesca Mulas +17 more

Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes

週刊教育資料(2023)10.1101/2022.12.31.522386
N/A
0DataRank · unranked
8 citations

Joshua Chiou, Chun Zeng, Michael Miller, Ileana Matta, Jee Yun Han +16 more

Genetic Discovery and Risk Prediction for Type 1 Diabetes in Individuals Without High-Risk HLA-DR3/DR4 Haplotypes

Diabetes Care(2024)10.2337/dc24-1251
N/A
0DataRank · unranked
14 citations

Joshua Chiou, Ruth Egamal, Amber M Luckett, Richard A. Oram, Paola Benaglio +2 more