John D. Sears

University of North Carolina at Chapel Hill

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 18 papers. Top paper: “Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity”.

Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00351

N/A

0.292DataRank · unranked

6 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2409166121

N/A

0DataRank · unranked

31 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +24 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01346

N/A

0DataRank · unranked

28 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Meganathan Nandakumar, Anand Vala +12 more

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

Viruses(2024)10.3390/v16040636

N/A

0DataRank · unranked

4 citations

John D. Sears, Che-Kang Chang, Jane Burdick, Isabella Law, Wes Sanders +6 more

Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.22.586341

N/A

0DataRank · unranked

7 citations

John D. Sears, Tina M. Leisner, P. Brian Hardy, Anirban Ghoshal, Mohammad Anwar Hossain +20 more

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.12.598722

N/A

0DataRank · unranked

2 citations

Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Peter J. Brown, Eric M. Merten, John D. Sears +7 more

Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice

PLoS ONE(2024)10.1371/journal.pone.0299595

N/A

0DataRank · unranked

0 citations

John J. Wilson, Sarah E. Heuer, John D. Sears, Jian Wei, Raghav Pandey +6 more

Universal Competition Assay by Nanopore Sequencing (U-CAN-Seq) v1

(2024)10.17504/protocols.io.kqdg3xjdzg25/v1

N/A

0DataRank · unranked

0 citations

John D. Sears, Wes Sanders, Che-Kang Chang, Paul W. Sylvester, Colton L. Linnertz +4 more

U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing

UNC Libraries(2024)10.17615/k948-9046

N/A

0DataRank · unranked

0 citations

Paul W. Sylvester, Martin T. Ferris, Wes Sanders, Jennifer Diaz, Isabella Law +6 more

Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c00635

N/A

0DataRank · unranked

9 citations

John D. Sears, Kacey M. Talbot, Yuan-Wei Norman Su, Scott Houliston, Mohammad Anwar Hossain +27 more

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

Scientific Reports(2025)10.1038/s41598-025-91673-x

N/A

0DataRank · unranked

9 citations

Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears +22 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01802

N/A

0DataRank · unranked

2 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

An Enantioselective Chemical Probe for Chikungunya nsP2 Helicase with Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650479

N/A

0DataRank · unranked

1 citations

Hans J. Oh, John D. Sears, Chun‐Hsing Chen, Anand Vala, Shubin Liu +20 more

N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.30.662352

N/A

0DataRank · unranked

1 citations

John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane Burdick +10 more

Identification of Spirodioxolane nsP2 Helicase Inhibitors with Antialphaviral Activity

ChemRxiv(2025)10.26434/chemrxiv-2025-mfts7

N/A

0DataRank · unranked

0 citations

John D. Sears, Muthu Bose Ramalingam, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

Identification of spirodioxolane nsP2 helicase inhibitors with antialphaviral activity

RSC Medicinal Chemistry(2025)10.1039/d5md00772k

N/A

0DataRank · unranked

0 citations

John D. Sears, M. Bose, Rahman Shah Zaib Saleem, Zachary W. Davis‐Gilbert, Mohammad Anwar Hossain +10 more

Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.24.537717

N/A

0DataRank · unranked

2 citations

John J. Wilson, Sarah E. Heuer, John D. Sears, Jian Wei, Raghav Pandey +6 more

Novel computational pipeline to identify target sites for broad spectrum antiviral drugs

Antiviral Research(2025)10.1016/j.antiviral.2025.106322

N/A

0DataRank · unranked

0 citations

Konstantin Popov, P. A. Sylvester, Rebekah J. Dickmander, Jennifer Loome-Diaz, Che-Kang Chang +14 more