Leonard D. Shultz

Also affiliated with University of Maine

Immunology and MicrobiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 39 papers. Top paper: “Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice”.

Human IL-6 fosters long-term engraftment of patient-derived disease-driving myeloma cells in immunodeficient mice

JCI Insight(2024)10.1172/jci.insight.177300

N/A

0.402DataRank · unranked

9 citations

Alfred L. Garfall, Lisa Burzenski, Leonard D. Shultz, Yan Tang, Siddhant Kadu +11 more

Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis

Nature Immunology(2020)10.1038/s41590-020-0783-5

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0DataRank · unranked

247 citations

Ming Lü, Jiayuan Shi, Zheng Gong, Li Hua, Qing Li +7 more

Innovations, challenges, and minimal information for standardization of humanized mice

EMBO Molecular Medicine(2020)10.15252/emmm.201708662

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0DataRank · unranked

138 citations

Christian Münz, Jan Jacob Schuringa, Karl‐Dimiter Bissig, Brian W. Soper, Terrence Meeham +18 more

Direct Tumor Killing and Immunotherapy through Anti-SerpinB9 Therapy

Cell(2020)10.1016/j.cell.2020.10.045

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0DataRank · unranked

100 citations

Yi‐Jun Wang, Jing Zhao, Mayuko Uehara, Qingming Hou, Vivek Kasinath +19 more

A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic‐related cytokine release syndrome

The FASEB Journal(2020)10.1096/fj.202001203r

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0DataRank · unranked

62 citations

Hongyuan Yang, Mingshan Cheng, Leonard D. Shultz, Dale L. Greiner, Michael A. Brehm +2 more

Tacrolimus- and sirolimus-induced human β cell dysfunction is reversible and preventable

JCI Insight(2020)10.1172/jci.insight.130770

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0DataRank · unranked

64 citations

John T. Walker, Alena Shostak, Ana Padgett, Erick Spears, Scott Wisniewski +10 more

Dapagliflozin Does Not Directly Affect Human α or β Cells

Endocrinology(2020)10.1210/endocr/bqaa080

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0DataRank · unranked

15 citations

John T. Walker, Alena Shostak, Yasir Bouchi, Greg Poffenberger, Nathaniel Hart +9 more

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

Journal of Leukocyte Biology(2020)10.1002/jlb.5ma0120-228r

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0DataRank · unranked

11 citations

Patricia Hernández-López, Sabine Heijhuurs, Laura Bongiovanni, Alain de Bruin, Dennis X. Beringer +7 more

Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice

Trends in Immunology(2020)10.1016/j.it.2020.06.004

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0DataRank · unranked

40 citations

Leonard D. Shultz, Fumihiko Ishikawa, Yoriko Saito

Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation

Genome biology(2020)10.1186/s13059-020-02086-0

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0DataRank · unranked

38 citations

Benjamin E. Low, Daniel Li, Grace A. Stafford, Vivek Kohar, Leonard D. Shultz +2 more

Improved mouse models and advanced genetic and genomic technologies for the study of neutrophils

Drug Discovery Today(2020)10.1016/j.drudis.2020.03.018

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0DataRank · unranked

4 citations

Daniel A. Skelly, Christopher Francis, Benjamin E. Low, Vivek Kohar, Lisa Burzenski +4 more

Humanized mice for immune system investigation: progress, promise and challenges

UNC Libraries(2020)10.17615/yar2-3h52

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0DataRank · unranked

0 citations

Dale L. Greiner, Leonard D. Shultz, J. Víctor García, Michael A. Brehm

Improvements and Limitations of Humanized Mouse Models for HIV Research: NIH/NIAID “Meet the Experts” 2015 Workshop Summary

UNC Libraries(2020)10.17615/822g-eq93

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0DataRank · unranked

0 citations

Jerome A. Zack, Brigitte E. Sanders-Beer, Kim J. Hasenkrug, Priti Kumar, Leonard D. Shultz +13 more

Novel phosphatidylserine-binding molecule enhances antitumor T-cell responses by targeting immunosuppressive exosomes in human tumor microenvironments

Journal for ImmunoTherapy of Cancer(2021)10.1136/jitc-2021-003148

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0DataRank · unranked

44 citations

Gautam N. Shenoy, Jenni Loyall, Brian D. Gray, Meghana V. Bapardekar, Alexis Conway +10 more

Role of MicroRNA in Inflammatory Bowel Disease: Clinical Evidence and the Development of Preclinical Animal Models

Cells(2021)10.3390/cells10092204

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0DataRank · unranked

36 citations

Jason A. Bubier, Michael V. Wiles, Leonard D. Shultz, Mansoor M. Amiji, Vishnu Hosur +1 more

Inactive rhomboid proteins RHBDF1 and RHBDF2 (iRhoms): a decade of research in murine models

Mammalian Genome(2021)10.1007/s00335-021-09910-3

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0DataRank · unranked

11 citations

Benjamin E. Low, Vivek Kohar, Leonard D. Shultz, Michael V. Wiles, Vishnu Hosur +1 more

Circulating CD34+ cells of primary myelofibrosis patients contribute to myeloid-dominant hematopoiesis and bone marrow fibrosis in immunodeficient mice

International Journal of Hematology(2021)10.1007/s12185-021-03239-y

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0DataRank · unranked

5 citations

Takuji Yamauchi, Noriaki Kawano, Rintaro Ono, Shuro Yoshida, Toshihiro Miyamoto +9 more

Preclinical evaluation of cancer immune therapy using patient‐derived tumor antigen‐specific T cells in a novel xenograft platform

Clinical & Translational Immunology(2021)10.1002/cti2.1246

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0DataRank · unranked

5 citations

Christopher Greene, Maulasri Bhatta, Miren L. Baroja, Jenni Loyall, Sathy V. Balu‐Iyer +6 more

Targeting critical kinases and anti-apoptotic molecules overcomes steroid resistance in MLL-rearranged leukaemia

EBioMedicine(2021)10.1016/j.ebiom.2021.103235

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0DataRank · unranked

4 citations

Yoriko Saito, Eiryo Kawakami, Mari Hashimoto, Yuki Aoki, Rintaro Ono +16 more

Clathrin light chain‐conjugated drug delivery for cancer

Bioengineering & Translational Medicine(2021)10.1002/btm2.10273

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0DataRank · unranked

4 citations

Liwei Jiang, Jing Zhao, Leonard D. Shultz, Dale L. Greiner, Munhyung Bae +8 more

Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment

Immunity(2022)10.1016/j.immuni.2022.07.001

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0DataRank · unranked

248 citations

Qing Li, Jiayuan Shi, Jian Wei, Peishan Li, Chih‐Hao Chang +3 more

Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

Cell Metabolism(2022)10.1016/j.cmet.2022.11.003

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0DataRank · unranked

122 citations

Qing Li, Jiayuan Shi, Edison T. Liu, Leonard D. Shultz, Guangwen Ren +1 more

Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg null mice expressing human IL15

The FASEB Journal(2022)10.1096/fj.202200045r

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0DataRank · unranked

56 citations

Lisa Burzenski, Li‐Chin Yao, James Keck, Dale L. Greiner, Leonard D. Shultz +2 more

Analysis of Salmonella Typhi Pathogenesis in a Humanized Mouse Model

Methods in molecular biology(2022)10.1007/978-1-0716-1971-1_18

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0DataRank · unranked

3 citations

Stephen J. Libby, Joyce E. Karlinsey, Michael A. Brehm, Dale L. Greiner, Leonard D. Shultz +3 more

Humanized mouse models for immuno-oncology research

Nature Reviews Clinical Oncology(2023)10.1038/s41571-022-00721-2

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0DataRank · unranked

371 citations

Hannah Buettner, Mina O. Seedhom, Dale L. Greiner, James Keck, Fumihiko Ishikawa +3 more

Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis

Science Immunology(2023)10.1126/sciimmunol.add5204

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0DataRank · unranked

120 citations

Qing Li, Jiayuan Shi, Peishan Li, Li Hua, Leonard D. Shultz +2 more

Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response

Science Advances(2023)10.1126/sciadv.ade9488

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0DataRank · unranked

25 citations

Minglin Ma, Atieh Sadraei, Hok Hei Tam, Shady Farah, Jennifer Hollister‐Lock +14 more

Simultaneous evaluation of treatment efficacy and toxicity for bispecific T‐cell engager therapeutics in a humanized mouse model

The FASEB Journal(2023)10.1096/fj.202300040r

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0DataRank · unranked

19 citations

Jing Jiao, Kyle Draheim, Guoxiang Yang, Hongyuan Yang, Li‐Chin Yao +11 more

Human Hematopoietic Stem Cell Engrafted IL-15 Transgenic NSG Mice Support Robust NK Cell Responses and Sustained HIV-1 Infection

Viruses(2023)10.3390/v15020365

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0DataRank · unranked

27 citations

Tridu R. Huynh, Abeera Mehmood, Teha Kim, Kayla Frank, Kefei Gao +5 more

NOD-scid IL2rγnull mice lacking TLR4 support human immune system development and the study of human-specific innate immunity

Journal of Leukocyte Biology(2023)10.1093/jleuko/qiac020

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0DataRank · unranked

10 citations

Leonard D. Shultz, Lisa Burzenski, Dale L. Greiner, Michael A. Brehm, Ken‐Edwin Aryee

Generation of the NeoThy mouse model for human immune system studies

Lab Animal(2023)10.1038/s41684-023-01196-z

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0DataRank · unranked

8 citations

Liupei Huang, Lydia Murphy, Jayalaxmi Suresh Babu, Cross Matthew Daffada, W. John Haynes +5 more

A human immune/muscle xenograft model of FSHD muscle pathology

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.17.567590

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0DataRank · unranked

2 citations

Jing Yan, Lisa Burzenski, Jamie Kady, Leonard D. Shultz, Michael A. Brehm +2 more

Nuclear factor kappa B-dependent persistence of Salmonella Typhi and Paratyphi in human macrophages

mBio(2024)10.1128/mbio.00454-24

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0DataRank · unranked

14 citations

Larissa A. Singletary, Fermin E. Guerra, Joyce E. Karlinsey, Stephen J. Libby, Sarah L. Jaslow +8 more

Human insulin as both antigen and protector in type 1 diabetes

European Journal of Immunology(2024)10.1002/eji.202350949

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0DataRank · unranked

4 citations

Leonard D. Shultz, Dale L. Greiner, Teresa P. DiLorenzo, Nitin Amdare

Human IL-6 fosters long-term engraftment of patient derived disease-driving myeloma cells in immunodeficient mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.21.576547

N/A

0DataRank · unranked

1 citations

Alfred L. Garfall, Lisa Burzenski, Leonard D. Shultz, Yan Tang, Siddhant Kadu +10 more

Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells v2

(2024)10.17504/protocols.io.36wgq4q43vk5/v2

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0DataRank · unranked

1 citations

Ken Edwin Aryee, Leonard D. Shultz, Dale L. Greiner, and Michael A. Brehm, Suheyla Hasgur

Generation of Immunodeficient Mice Bearing Human Immune Systems by the Engraftment of Hematopoietic Stem Cells v3

(2024)10.17504/protocols.io.36wgq4q43vk5/v3

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0DataRank · unranked

0 citations

Ken Edwin Aryee, Leonard D. Shultz, Dale L. Greiner, and Michael A. Brehm, Suheyla Hasgur

Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status

Nature Communications(2020)10.1038/s41467-020-18125-0

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0DataRank · unranked

157 citations

Ming Lü, Jiayuan Shi, Li Hua, Zheng Gong, Qing Li +3 more

Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model

Journal of Pharmaceutical Sciences(2025)10.1016/j.xphs.2025.103964

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0DataRank · unranked

0 citations

Lisa Burzenski, Michael A. Brehm, Dale L. Greiner, Sathy V. Balu‐Iyer, Leonard D. Shultz +1 more