Lee M

Also affiliated with Wellcome Sanger Institute

MedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 26 papers. Top paper: “A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin”.

A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin

Nature Communications(2022)10.1038/s41467-022-33403-9

N/A

0.624DataRank · unranked

63 citations

Jinxin V. Pei, James E. O. Rosling, Vandana Thathy, Dongdi Li, Yi Xue +26 more

MK-7602: a potent multi-stage dual-targeting antimalarial

EBioMedicine(2025)10.1016/j.ebiom.2025.106061

N/A

0.292DataRank · unranked

6 citations

Josephine Palandri, Manuel de Lera Ruiz, Wendy Bailey, Christopher W. Boyce, Andrew Danziger +34 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Research Square(2024)10.21203/rs.3.rs-5412515/v1

N/A

0.104DataRank · unranked

1 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

MalDA, Accelerating Malaria Drug Discovery

Trends in Parasitology(2021)10.1016/j.pt.2021.01.009

N/A

0DataRank · unranked

118 citations

Sabine Ottilie, Eva S. Istvan, Karla P. Godinez‐Macias, Amanda K. Lukens, Beatriz Baragaña +18 more

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Cell chemical biology(2021)10.1016/j.chembiol.2021.07.010

N/A

0DataRank · unranked

82 citations

Charisse Flerida A. Pasaje, João Pedro Pisco, Josefine Striepen, Madeline R. Luth, Krittikorn Kümpornsin +29 more

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine

The Journal of Infectious Diseases(2022)10.1093/infdis/jiac469

N/A

0DataRank · unranked

26 citations

Peter Christensen, Annie Racklyeft, Satish K. Dhingra, Adeline C. Y. Chua, Caroline Remmert +13 more

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Science Translational Medicine(2023)10.1126/scitranslmed.adc9249

N/A

0DataRank · unranked

27 citations

Francisco M. Guerra, Matthew Abraham, Kuo‐Sen Huang, Frances Rocamora, Haoshuang Zhao +22 more

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance

Science(2024)10.1126/science.adk9893

N/A

0DataRank · unranked

26 citations

Karla P. Godinez‐Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng +43 more

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of Plasmodium falciparum Phosphatidylinositol-4-kinase and Hemozoin Formation with In Vivo Efficacy

Journal of Medicinal Chemistry(2024)10.1021/acs.jmedchem.4c01154

N/A

0DataRank · unranked

22 citations

Donald Seanego, Stephen Fienberg, Monica Clements, Jasmin Ferreira, Venkata S. Sypu +30 more

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

PLoS Pathogens(2024)10.1371/journal.ppat.1012627

N/A

0DataRank · unranked

8 citations

Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, John Okombo, Juliana Calit, Diana Fontinha +12 more

β-Carboline-3-carboxamide Antimalarials: Structure–Activity Relationship, ADME-Tox Studies, and Resistance Profiling

ACS Infectious Diseases(2024)10.1021/acsinfecdis.4c00653

N/A

0DataRank · unranked

6 citations

Bo Zhou, Reagan S. Haney, Kevin A. Kunz, Leticia S. Do Amaral, Rudraneel Roy Chowdhury +14 more

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.23.590861

N/A

0DataRank · unranked

2 citations

Gilda Padalino, Tomas Yeo, Andrea Brancale, David A. Fidock, Karl F. Hoffmann +2 more

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615529

N/A

0DataRank · unranked

0 citations

Sachel Mok, Tomas Yeo, Melanie J. Shears, Jin H. Jeon, Sunil Kumar Narwal +23 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

npj Drug Discovery.(2025)10.1038/s44386-025-00006-5

N/A

0DataRank · unranked

11 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity

Cell chemical biology(2025)10.1016/j.chembiol.2025.06.003

N/A

0DataRank · unranked

9 citations

Tiantian Jiang, Lushun Wang, Monica J. Bohmer, Subhoja Chakraborty, John Okombo +32 more

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

PLoS Pathogens(2025)10.1371/journal.ppat.1012216

N/A

0DataRank · unranked

5 citations

Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale +4 more

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01417

N/A

0DataRank · unranked

3 citations

Mmakwena M. Mmonwa, Dina Coertzen, Liezl Krugmann, Nicolaas Salomane, Meta Leshabane +18 more

YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates

Scientific Reports(2025)10.1038/s41598-025-85346-y

N/A

0DataRank · unranked

1 citations

Mukul Rawat, Rachael Coyle, Lionel Brice Feufack-Donfack, Malen Ea, Ágnes Orbán +11 more

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of Pf Ark1 and Hemozoin Formation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.17.664511

N/A

0DataRank · unranked

4 citations

John G. Woodland, Larnelle F. Garnie, Henrico Langeveld, Dale Taylor, Luiz C. Godoy +24 more

Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.06.666330

N/A

0DataRank · unranked

0 citations

Nonlawat Boonyalai, Cindy Smidt, Madeline R. Luth, Daisy Chen, Andrew Plater +12 more

Optimization of 2,8-Diaryl-1,5-naphthyridines as Plasmodium falciparum Phosphatidylinositol 4-Kinase Inhibitors with Improved ADME Profiles and In Vivo Efficacy

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c02248

N/A

0DataRank · unranked

0 citations

Donald Seanego, Stephen Fienberg, Venkata S. Sypu, Nicolaas Salomane, Liezl Krugmann +13 more

Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in Plasmodium HSP90 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.684657

N/A

0DataRank · unranked

0 citations

Amanda K. Lukens, Mariana Laureano de Souza, Alex Foy, Jason Hsiao, Tolla Ndiaye +18 more

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Cell chemical biology(2020)10.1016/j.chembiol.2020.04.001

N/A

0DataRank · unranked

91 citations

James M. Murithi, Charisse Flerida A. Pasaje, Sonja Ghidelli‐Disse, Louis Dwomoh, Megan J. Bird +26 more

Mechanistic insights into dual-active liver and blood-stage antiplasmodials

mBio(2025)10.1128/mbio.02423-25

N/A

0DataRank · unranked

0 citations

Nonlawat Boonyalai, Cindy Smidt, Madeline R. Luth, Daisy Chen, Andrew Plater +12 more

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

PLoS Pathogens(2020)10.1371/journal.ppat.1008482

N/A

0DataRank · unranked

89 citations

Barbara H. Stokes, Rachel L. Edwards, Gavreel Kalantarov, Kim C. Heimsch, Michal Kuderjavy +9 more

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

Nature Communications(2020)10.1038/s41467-020-15440-4

N/A

0DataRank · unranked

57 citations

Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth +21 more