Yury S. Polikanov

Biochemistry, Genetics and Molecular BiologyMedicineEnvironmental Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 39 papers. Top paper: “Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens”.

Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00665

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0DataRank · unranked

51 citations

Riccardo Sola, Bertrand Beckert, Erica Valencic, Dominic W. P. Collis, Jure Borišek +10 more

Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome

Proceedings of the National Academy of Sciences(2020)10.1073/pnas.2008671117

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49 citations

Ivan B. Lomakin, Yury S. Polikanov, Christopher G. Bunick, Zahra Batool

Insights into the improved macrolide inhibitory activity from the high-resolution cryo-EM structure of dirithromycin bound to the E. coli 70S ribosome

RNA(2020)10.1261/rna.073817.119

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27 citations

Alena Paleskava, Andrey G. Tereshchenkov, Pavel Kasatsky, Ekaterina S. Komarova, Dmitrii I. Shiriaev +8 more

Erratum for Khabibullina et al., “Structure of Dirithromycin Bound to the Bacterial Ribosome Suggests New Ways for Rational Improvement of Macrolides”

Antimicrobial Agents and Chemotherapy(2020)10.1128/aac.02360-19

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0 citations

Andrey G. Tereshchenkov, Ekaterina S. Komarova, Egor A. Syroegin, Dmitrii I. Shiriaev, Alena Paleskava +8 more

A synthetic antibiotic class overcoming bacterial multidrug resistance

Nature(2021)10.1038/s41586-021-04045-6

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234 citations

Amarnath Pisipati, Egor A. Syroegin, Katherine J. Silvestre, Dorota Klepacki, Jeremy D. Mason +10 more

Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance

Nature Chemical Biology(2021)10.1038/s41589-020-00715-0

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142 citations

Egor A. Syroegin, Elena V. Aleksandrova, Gemma C. Atkinson, Steven T. Gregory, Alexander S. Mankin +2 more

A selective antibiotic for Lyme disease

Cell(2021)10.1016/j.cell.2021.09.011

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62 citations

Xiaoqian Wu, Yu Imai, Madeleine Morrissette, Norman Pitt, Quentin Favre-Godal +23 more

Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome

Antibiotics(2021)10.3390/antibiotics10040390

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28 citations

Julia A. Pavlova, Dmitrii A. Lukianov, Andrey G. Tereshchenkov, G. I. Makarov, Zimfira Z. Khairullina +8 more

Structural basis for the context-specific action of classic peptidyl transferase inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.17.448903

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5 citations

Laurin Flemmich, Dorota Klepacki, Nora Vázquez‐Laslop, Ronald Micura, Yury S. Polikanov +1 more

Structural basis for PoxtA-mediated resistance to Phenicol and Oxazolidinone antibiotics

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.18.448924

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5 citations

Victoriia Murina, Marje Kasari, Hiraku Takada, Kathryn Jane Turnbull, Yury S. Polikanov +6 more

A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens

ChemRxiv(2021)10.26434/chemrxiv.14331407

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5 citations

Amarnath Pisipati, Egor A. Syroegin, Katherine J. Silvestre, Dorota Klepacki, J. F. A. MASON +10 more

A Synthetic Antibiotic Scaffold Effective Against Multidrug-Resistant Bacterial Pathogens

ChemRxiv(2021)10.26434/chemrxiv.14331407.v1

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4 citations

Amarnath Pisipati, Egor A. Syroegin, Katherine J. Silvestre, Dorota Klepacki, J. F. A. MASON +10 more

Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol

Nature Structural & Molecular Biology(2022)10.1038/s41594-022-00720-y

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89 citations

Laurin Flemmich, Dorota Klepacki, Nora Vázquez‐Laslop, Ronald Micura, Yury S. Polikanov +1 more

Insights into the ribosome function from the structures of non-arrested ribosome–nascent chain complexes

Nature Chemistry(2022)10.1038/s41557-022-01073-1

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47 citations

Elena V. Aleksandrova, Yury S. Polikanov, Egor A. Syroegin

Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine

Nucleic Acids Research(2022)10.1093/nar/gkac548

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32 citations

Elena V. Aleksandrova, Yury S. Polikanov, Egor A. Syroegin

Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin

Nucleic Acids Research(2022)10.1093/nar/gkac1189

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10 citations

Valeria I. Marina, Aleksandr A. Grachev, Tinashe P. Maviza, Olga Tolicheva, Alena Paleskava +6 more

Insights into the ribosome function from the structures of non-arrested ribosome nascent chain complexes

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.21.480960

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5 citations

Elena V. Aleksandrova, Yury S. Polikanov, Egor A. Syroegin

Inhibition of translation termination by Drosocin, an antimicrobial peptide from fruit flies

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.11.519952

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1 citations

Dorota Klepacki, Irueosa Ohanmu, Chetana Baliga, Weiping Huang, Alexandra Brakel +6 more

Inhibition of translation termination by the antimicrobial peptide Drosocin

Nature Chemical Biology(2023)10.1038/s41589-023-01300-x

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50 citations

Dorota Klepacki, Irueosa Ohanmu, Chetana Baliga, Weiping Huang, Alexandra Brakel +6 more

Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A

Nature Communications(2023)10.1038/s41467-023-39653-5

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38 citations

Nadja Leimer, Egor A. Syroegin, Clémence F. Dunand, Zackery P. Bulman, Kim Lewis +3 more

Synthesis of Peptidyl-tRNA Mimics for Structural Biology Applications

Accounts of Chemical Research(2023)10.1021/acs.accounts.3c00412

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13 citations

Mélanie Ethève‐Quelquejeu, Ronald Micura, Yury S. Polikanov

Practical Synthesis of N-Formylmethionylated Peptidyl-tRNA Mimics

ACS Chemical Biology(2023)10.1021/acschembio.3c00237

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3 citations

Egor A. Syroegin, Kathrin Breuker, Yury S. Polikanov, Ronald Micura, Julia Thaler

Conserved 5-methyluridine tRNA modification modulates ribosome translocation

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.12.566704

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5 citations

Monika K. Franco, Mehmet Tardu, T.J. Smith, Laura R. Snyder, Daniel E. Eyler +5 more

Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.27.559749

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2 citations

Kelvin J. Y. Wu, Ben I. C. Tresco, Egor A. Syroegin, Erin E. Killeavy, Samson M. Balasanyants +6 more

An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance

Science(2024)10.1126/science.adk8013

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75 citations

Ben I. C. Tresco, Antonio Ramkissoon, Elena V. Aleksandrova, Egor A. Syroegin, Dominic N. Y. See +10 more

Macrolones target bacterial ribosomes and DNA gyrase and can evade resistance mechanisms

Nature Chemical Biology(2024)10.1038/s41589-024-01685-3

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37 citations

Cong-Xuan Ma, Dorota Klepacki, Faezeh Alizadeh, Nora Vázquez‐Laslop, Jian‐Hua Liang +3 more

Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it

Nature Chemical Biology(2024)10.1038/s41589-023-01525-w

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25 citations

Kelvin J. Y. Wu, Ben I. C. Tresco, Egor A. Syroegin, Erin E. Killeavy, Samson M. Balasanyants +6 more

Activity, structure, and diversity of Type II proline-rich antimicrobial peptides from insects

EMBO Reports(2024)10.1038/s44319-024-00277-5

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17 citations

Chetana Baliga, Elena V. Aleksandrova, Gemma C. Atkinson, Yury S. Polikanov, Nora Vázquez‐Laslop +2 more

Conserved 5-methyluridine tRNA modification modulates ribosome translocation

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2401743121

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18 citations

Monika K. Franco, Rachel Giles, Daniel E. Eyler, Mehmet Tardu, T.J. Smith +6 more

Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2314101120

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12 citations

Martin N. Cheramie, Dinesh M. Fernando, Petra Selchow, Christopher J. Meyer, Samanthi L. Waidyarachchi +20 more

Berberine analog of chloramphenicol exhibits a distinct mode of action and unveils ribosome plasticity

Structure(2024)10.1016/j.str.2024.06.013

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8 citations

Julia A. Pavlova, Madhura N. Paranjpe, Andrey G. Tereshchenkov, Dmitrii A. Lukianov, Ilya А. Osterman +4 more

Rationally designed pooled CRISPRi-seq uncovers an inhibitor of bacterial peptidyl-tRNA hydrolase

Cell Reports(2024)10.1016/j.celrep.2024.114967

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2 citations

Egor A. Syroegin, Julieta Novomisky Nechcoff, Archit Devarajan, Yury S. Polikanov, Silvia T. Cardona +1 more

A Broad Spectrum Lasso Peptide Antibiotic Targeting the Bacterial Ribosome

Research Square(2024)10.21203/rs.3.rs-5058118/v1

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3 citations

Manoj Jangra, Dmitrii Y. Travin, Е Н Александрова, Manpreet Kaur, Lena Darwish +10 more

Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNA Gly and tRNA Thr

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.05.602228

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1 citations

Masaki Takegawa, Takayuki Ohira, Egor A. Syroegin, Gemma C. Atkinson, Marcus Johansson +5 more

Mechanism of release factor–mediated peptidyl-tRNA hydrolysis on the ribosome

Science(2025)10.1126/science.ads9030

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10 citations

Egor A. Syroegin, Ritwika Basu, Alexander A. Vassilevski, Matthieu G. Gagnon, Yury S. Polikanov +1 more

Discovery of a fluorinated macrobicyclic antibiotic through chemical synthesis

Nature Chemistry(2025)10.1038/s41557-025-01738-7

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7 citations

Kelvin J. Y. Wu, Antonio Ramkissoon, Elena V. Aleksandrova, Michael Purdy, Dominic N. Y. See +4 more

Structural insights into context-specific inhibition of bacterial translation by macrolides

Nature Communications(2025)10.1038/s41467-025-64692-5

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4 citations

Elena V. Aleksandrova, Artem A. Kruglov, Madhura N. Paranjpe, Maxim S. Svetlov, Yury S. Polikanov +1 more

Why sulfur is important in lincosamide antibiotics

Chem(2025)10.1016/j.chempr.2025.102480

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0 citations

Elena V. Aleksandrova, Paul J. Robinson, Amy E. Benedetto, M. C. Z. Yu, Ben I.C. Tresco +9 more

Engineering Pleuromutilin Epimers to Engage an Unexploited Ribosomal Binding Pocket

ChemRxiv(2025)10.26434/chemrxiv-2025-42sv4

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0 citations

Micah Hoernig, Benjamin Y. Killam, Marion Q. LoPresti, Abdallah S. Abdelsattar, Ahmed A Abouelkhair +9 more