Johan Auwerx

École Polytechnique Fédérale de Lausanne

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 32 papers. Top paper: “Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice”.

Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice

Aging Cell(2020)10.1111/acel.13195

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143 citations

Ludger J.E. Goeminne, Jung Tae Kim∥, Jing Tian, Seok‐Hwan Kim, Ha Thi Nga +10 more

Long noncoding RNA SNHG12 integrates a DNA-PK–mediated DNA damage response and vascular senescence

Science Translational Medicine(2020)10.1126/scitranslmed.aaw1868

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137 citations

Dafeng Yang, Xinghui Sun, Debapria Das, Siavash Ghaffari, Roberto Molinaro +18 more

Mouse Systems Genetics as a Prelude to Precision Medicine

Trends in Genetics(2020)10.1016/j.tig.2020.01.004

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74 citations

Johan Auwerx, Hao Li

Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models

Experimental Neurology(2020)10.1016/j.expneurol.2020.113219

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73 citations

Kelby M. Killoy, Mariana Pehar, Liping Liu, Johan Auwerx, Marcelo R. Vargas +1 more

The Gene-Regulatory Footprint of Aging Highlights Conserved Central Regulators

Cell Reports(2020)10.1016/j.celrep.2020.108203

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43 citations

Pooja Jha, Riekelt H. Houtkooper, Robert W. Williams, Xu Wang, Johan Auwerx +1 more

Sirt6 deletion in bone marrow-derived cells increases atherosclerosis – Central role of macrophage scavenger receptor 1

Journal of Molecular and Cellular Cardiology(2020)10.1016/j.yjmcc.2020.01.002

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37 citations

Jürgen Pahla, Lambertus J. van Tits, Lavinia Bisceglie, Daniel S. Gaul, Sarah Costantino +19 more

A platform for experimental precision medicine: The extended BXD mouse family

Cell Systems(2021)10.1016/j.cels.2020.12.002

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206 citations

Danny Arends, Pjotr Prins, Megan K. Mulligan, Suheeta Roy, Evan G. Williams +11 more

Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression

Gastroenterology(2021)10.1053/j.gastro.2021.06.045

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124 citations

Surendra K. Shukla, Enza Vernucci, Chunbo He, Dezhen Wang, Ryan J. King +26 more

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

Nature Communications(2021)10.1038/s41467-021-27422-1

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47 citations

Haikel Dridi, Steven Reiken, Tanes Lima, Chris Donnelly, Umberto De Marchi +11 more

Gene-by-environment modulation of lifespan and weight gain in the murine BXD family

Nature Metabolism(2021)10.1038/s42255-021-00449-w

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52 citations

Maroun Bou Sleiman, Pooja Jha, Jesse Ingels, Casey J. Chapman, Melinda S. McCarty +23 more

Sex- and age-dependent genetics of longevity in a heterogeneous mouse population

Science(2022)10.1126/science.abo3191

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82 citations

Suheeta Roy, Arwen W. Gao, Marie C. Sadler, Giacomo von Alvensleben, Hao Li +9 more

eNAMPT actions through nucleus accumbens NAD + /SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress

Science Advances(2022)10.1126/sciadv.abj9109

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55 citations

Simone Astori, Ioannis Zalachoras, João Rodrigues, Sriparna Ghosal, Wei Huang +7 more

COX7A2L genetic variants determine cardiorespiratory fitness in mice and human

Nature Metabolism(2022)10.1038/s42255-022-00655-0

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37 citations

Maroun Bou Sleiman, Martin Wohlwend, Sandra Rodríguez-López, Ludger J.E. Goeminne, Pirkka‐Pekka Laurila +11 more

Mitophagy in human health, ageing and disease

Nature Metabolism(2023)10.1038/s42255-023-00930-8

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555 citations

Julie Faitg, Johan Auwerx, Luigi Ferrucci, Davide D’Amico, Anna Picca

Upregulation of the ERRγ–VDAC1 axis underlies the molecular pathogenesis of pancreatitis

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219644120

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16 citations

Themis Thoudam, Ibotombi Singh Sinam, Chae Won Lim, Myeongjin Kim, Jiale Wang +18 more

Mass Spectrometry-Based Multi-omics Integration with a Single Set of C. elegans Samples

Analytical Chemistry(2023)10.1021/acs.analchem.3c00734

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10 citations

Annie Jen, Katherine A. Overmyer, Arwen W. Gao, Evgenia Shishkova, Johan Auwerx +2 more

Gene network based analysis identifies a coexpression module involved in regulating plasma lipids with high-fat diet response

The Journal of Nutritional Biochemistry(2023)10.1016/j.jnutbio.2023.109398

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3 citations

Jesse D. Ziebarth, Ludger J.E. Goeminne, Jun Gao, Evan G. Williams, L. Darryl Quarles +6 more

Embracing cancer complexity: Hallmarks of systemic disease

Cell(2024)10.1016/j.cell.2024.02.009

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481 citations

Elsa Bernard, Chris Abbosh, Fabrice Andre, Johan Auwerx, Allan Balmain +28 more

ACMSD inhibition corrects fibrosis, inflammation, and DNA damage in MASLD/MASH

Journal of Hepatology(2024)10.1016/j.jhep.2024.08.009

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31 citations

Masaki Kimura, Xiaoxu Li, Jonathan Sulc, Qi Wang, Sandra Rodríguez-López +11 more

Skeletal Muscle SIRT3 Deficiency Contributes to Pulmonary Vascular Remodeling in Pulmonary Hypertension Due to Heart Failure With Preserved Ejection Fraction

Circulation(2024)10.1161/circulationaha.124.068624

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23 citations

Yang Bai, Kentaro Noda, Joshua R. Huot, Todd Cook, Amanda Fisher +12 more

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

Cell Reports(2024)10.1016/j.celrep.2024.114836

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6 citations

Gaby El Alam, Yunyun Zhu, Weisha Li, Jonathan Sulc, Xiaoxu Li +12 more

Failure of metabolic checkpoint control during late-stage granulopoiesis drives neutropenia in reticular dysgenesis

Blood(2024)10.1182/blood.2024024123

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3 citations

Martin Arreola, Thomas P. Mathews, Andrew DeVilbiss, Zhiyu Zhao, Misty S. Martin-Sandoval +13 more

Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.24.581864

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2 citations

Bastian Ramms, Chun Zeng, Jacqueline R. Benthuysen, Somesh Sai, Dennis P. Pollow +12 more

High-content phenotypic analysis of a C. elegans recombinant inbred population identifies genetic and molecular regulators of lifespan

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.15.575638

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1 citations

Gaby El Alam, Yunyun Zhu, Weisha Li, Elena Katsyuba, Jonathan Sulc +12 more

A consensus guide to preclinical indirect calorimetry experiments

Nature Metabolism(2025)10.1038/s42255-025-01360-4

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22 citations

David B. Allison, Thierry Alquier, Md Ansarullah, Steven N. Austad, Johan Auwerx +74 more

NAD+ boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice

Atherosclerosis(2025)10.1016/j.atherosclerosis.2025.119188

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8 citations

Daniel S. Gaul, Era Gorica, Jürgen Pahla, Zeneng Wang, S A Mohammed +12 more

The protein deacetylase SIRT2 exerts metabolic control over adaptive β cell proliferation

Journal of Clinical Investigation(2025)10.1172/jci187020

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3 citations

Bastian Ramms, Chun Zeng, Jacqueline R. Benthuysen, Somesh Sai, Dennis P. Pollow +15 more

Genetic Modulation of Lifespan: Dynamic Effects, Sex Differences, and Body Weight Trade-offs

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.27.649857

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1 citations

David G. Ashbrook, Suheeta Roy, Lu Lu, Zachary Sloan, Arthur G. Centeno +19 more

A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.19.639093

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0 citations

Pablo Ranea‐Robles, Evan G. Williams, Mina Mirzaian, J. Alexander Heimel, Christiaan N. Levelt +7 more

A Multiomic Network Approach to Uncover Disease Modifying Mechanisms of Inborn Errors of Metabolism

Journal of Inherited Metabolic Disease(2025)10.1002/jimd.70045

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0 citations

Pablo Ranea‐Robles, Evan G. Williams, Mina Mirzaian, J. Alexander Heimel, Christiaan N. Levelt +7 more

Genetic mapping of lifespan and mitochondrial stress response in C. elegans

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.26.661693

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0 citations

Weisha Li, Arwen W. Gao, Yunyun Zhu, Elena Katsyuba, Katherine A. Overmyer +11 more

Genetic mapping of lifespan and mitochondrial stress response in C. elegans

Research Square(2025)10.21203/rs.3.rs-7093535/v1

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0 citations

Xiaoxu Li, Weisha Li, Arwen W. Gao, Yunyun Zhu, Elena Katsyuba +11 more