Dennis Lal

Also affiliated with Cleveland Clinic, University of Cologne, The University of Texas at Arlington, Cleveland Clinic Lerner College of Medicine, Cook Children's Medical Center, Cook Children's Health Care System, The University of Texas Health Science Center, The Neurological Institute, The University of Texas Health Science Center at Houston

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.4Author DataRank

Indexed papers

4in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 4 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A cross-disorder dosage sensitivity map of the human genome

Cell(2022)10.1016/j.cell.2022.06.036

Top 5%

4.7DataRank

Top 5%367 citations

Joseph Glessner, Eleonora Porcu, Maarja Lepamets, Rhonda Brandon, Christopher Lauricella +46 more

Papers

Driven by 34 papers — median percentile 80. Top paper: “A cross-disorder dosage sensitivity map of the human genome”.

A cross-disorder dosage sensitivity map of the human genome

Cell(2022)10.1016/j.cell.2022.06.036

Top 5%

4.7DataRank

Top 5%367 citations

Joseph Glessner, Eleonora Porcu, Maarja Lepamets, Rhonda Brandon, Christopher Lauricella +46 more

Lessons learned from 40 novel PIGA patients and a review of the literature

Epilepsia(2020)10.1111/epi.16545

Top 10%

2.0DataRank

Top 10%58 citations

Alexej Knaus, Manuela Pendziwiat, Alexandra Afenjar, Tahsin Stefan Barakat, Friedrich Bosch +49 more

A cross-disorder dosage sensitivity map of the human genome

medRxiv(2021)10.1101/2021.01.26.21250098

N/A

2.0DataRank · unranked

54 citations

Joseph Glessner, Eleonora Porcu, Lisa‐Marie Niestroj, Jacob C. Ulirsch, Georgios Kellaris +28 more

Genome-wide identification and phenotypic characterization of seizure-associated copy number variations in 741,075 individuals

Nature Communications(2023)10.1038/s41467-023-39539-6

N/A

1.2DataRank · unranked

56 citations

David Lewis‐Smith, Ryan L. Collins, Lisa‐Marie Niestroj, Shridhar Parthasarathy, Julie Xian +94 more

SLC6A1 variant pathogenicity, molecular function and phenotype: a genetic and clinical analysis

Brain(2023)10.1093/brain/awad292

Top 30%

0.660DataRank

Top 30%23 citations

Eduardo Pérez‐Palma, Tobias Brünger, Ludovica Montanucci, Cornelius Gati, Chiara Klöckner +41 more

Shared genetic basis between genetic generalized epilepsy and background electroencephalographic oscillations

Epilepsia(2021)10.1111/epi.16922

N/A

0DataRank · unranked

15 citations

Jurjen J. Luykx, Bochao Lin, Costin Leu, Dennis Lal, Alexander Smith +11 more

Application of single cell genomics to focal epilepsies: A call to action

Brain Pathology(2021)10.1111/bpa.12958

N/A

0DataRank · unranked

12 citations

Dennis Lal, Christopher A. Walsh, Sattar Khoshkhoo

Identification and quantification of oligogenic loss-of-function disorders

Genetics in Medicine(2021)10.1016/j.gim.2021.10.026

N/A

0DataRank · unranked

4 citations

Eduardo Pérez‐Palma, Marko Mrdjen, Megan McHugh, Costin Leu, Dennis Lal +1 more

The gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications

Brain(2022)10.1093/brain/awac210

N/A

0DataRank · unranked

158 citations

Tobias Brünger, Tony Feng, Carmen Fons, Anni Lehikoinen, Eleni Panagiotakaki +30 more

Development and Validation of a Prediction Model for Early Diagnosis of SCN1A -Related Epilepsies

Neurology(2022)10.1212/wnl.0000000000200028

N/A

0DataRank · unranked

73 citations

Eduardo Pérez‐Palma, Ismael Ghanty, Xinge Ji, Eva H. Brilstra, Berten Ceulemans +17 more

Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene

Neurology(2022)10.1212/wnl.0000000000201471

N/A

0DataRank · unranked

55 citations

Ingmar Blümcke, Melodie R. Winawer, Till Hartlieb, Hoon‐Chul Kang, Laura Grisotto +31 more

Delineation of functionally essential protein regions for 242 neurodevelopmental genes

Brain(2022)10.1093/brain/awac381

N/A

0DataRank · unranked

17 citations

Tobias Brünger, Eduardo Pérez‐Palma, Marie Macnee, Andreas Brunklaus, Mark J. Daly +5 more

Data-driven historical characterization of epilepsy-associated genes

European Journal of Paediatric Neurology(2022)10.1016/j.ejpn.2022.12.005

N/A

0DataRank · unranked

36 citations

Eduardo Pérez‐Palma, Javier A. López-Rivera, Alina Ivaniuk, Patrick May, Rikke S. Møller +2 more

Conserved patterns across ion channels correlate with variant pathogenicity and clinical phenotypes

Brain(2022)10.1093/brain/awac305

N/A

0DataRank · unranked

26 citations

Eduardo Pérez‐Palma, Ludovica Montanucci, Michael Nothnagel, Rikke S. Møller, Stéphanie Schorge +8 more

Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With KCNC2 Pathogenic Variants

Neurology(2022)10.1212/wnl.0000000000200660

N/A

0DataRank · unranked

21 citations

Simone Seiffert, Manuela Pendziwiat, Annika Rademacher, Tobias Brünger, Ulrike B. S. Hedrich +43 more

Genetic and molecular features of seizure-freedom following surgical resections for focal epilepsy: A pilot study

Frontiers in Neurology(2022)10.3389/fneur.2022.942643

N/A

0DataRank · unranked

10 citations

Robyn M. Busch, Dennis Lal, Jennifer Hockings, Olivia Hogue, Marcia Morita‐Sherman +8 more

Severe communication delays are independent of seizure burden and persist despite contemporary treatments in SCN1A+ Dravet syndrome: Insights from the ENVISION natural history study

Epilepsia(2023)10.1111/epi.17850

N/A

0DataRank · unranked

24 citations

Ingrid E Scheffer, Joseph Sullivan, Andreas Brunklaus, Susana Boronat, James W. Wheless +24 more

Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function

Human Molecular Genetics(2023)10.1093/hmg/ddad104

N/A

0DataRank · unranked

25 citations

Hongjie Yuan, Riley E. Perszyk, Jing Zhang, Sukhan Kim, Kelsey A. Nocilla +7 more

Epilepsies of presumed genetic etiology show enrichment of rare variants that occur in the general population

The American Journal of Human Genetics(2023)10.1016/j.ajhg.2023.06.004

N/A

0DataRank · unranked

3 citations

Yin-Yuan Su, Siwei Chen, Akhil Velluva, Anna Kirstein, Antje Garten +9 more

Pathogenic paralogous variants can be used to apply the ACMG PS1 and PM5 variant interpretation criteria

medRxiv(2023)10.1101/2023.08.22.23294353

N/A

0DataRank · unranked

5 citations

Alina Ivaniuk, Eduardo Pérez‐Palma, Ludovica Montanucci, Stacey Cohen, Lacey Smith +6 more

Analysis of 1386 epileptogenic brain lesions reveals association with DYRK1A and EGFR

Nature Communications(2024)10.1038/s41467-024-54911-w

N/A

0DataRank · unranked

22 citations

Costin Leu, Tobias Brünger, Lucas Hoffmann, Sara Baldassari, Mathilde Chipaux +18 more

Conserved missense variant pathogenicity and correlated phenotypes across paralogous genes

Research Square(2024)10.21203/rs.3.rs-5434140/v1

N/A

0DataRank · unranked

0 citations

Alina Ivanuk, Eduardo Pérez‐Palma, Ludovica Montanucci, Stacey Cohen, Lacey Smith +6 more

Genome-wide association meta-analyses of drug-resistant epilepsy

EBioMedicine(2025)10.1016/j.ebiom.2025.105675

N/A

0DataRank · unranked

12 citations

Andreja Avberšek, Remi Stevelink, Helena Martins Custodio, Siwei Chen, Doug Speed +88 more

Polygenic score analysis identifies distinct genetic risk profiles in Alzheimer’s disease comorbidities

Scientific Reports(2025)10.1038/s41598-025-95755-8

N/A

0DataRank · unranked

5 citations

Camilo Villamán, Costin Leu, Dennis Lal, Ignácio F. Mata, Andrés D. Klein +2 more

Ontology accelerates few-shot learning capability of large language model: A study in extraction of drug efficacy in a rare pediatric epilepsy

International Journal of Medical Informatics(2025)10.1016/j.ijmedinf.2025.105942

N/A

0DataRank · unranked

5 citations

Katrina Prantzalos, Veronica Hood, Mary Anne Meskis, Lori L. Isom, Karen S. Wilcox +14 more

Polygenic scores contribution to Parkinson’s disease comorbidities

Brain Communications(2025)10.1093/braincomms/fcaf325

N/A

0DataRank · unranked

2 citations

Camilo Villamán, Cristián Tejos, Gabriela M. Repetto, Costin Leu, Dennis Lal +4 more

Cognitive stagnation and executive function deficits in young children with SCN1A + Dravet syndrome: Detailed characterization of onset, progression, and impact in the ENVISION natural history study

Epilepsia(2025)10.1111/epi.70015

N/A

0DataRank · unranked

1 citations

M. Scott Perry, Ingrid E Scheffer, James W. Wheless, Susana Boronat, Andreas Brunklaus +24 more

Long-Term Seizure Reduction Associated with Vagal Nerve Stimulation in Dravet Syndrome

medRxiv(2025)10.1101/2024.12.30.24319582

N/A

0DataRank · unranked

0 citations

Alina Ivaniuk, Tobias Bruenger, Émile Moura Coelho Da Silva, Emily A. Huth, Ludovica Montanucci +16 more

Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects

Brain(2020)10.1093/brain/awaa171

N/A

0DataRank · unranked

81 citations

Eduardo Pérez‐Palma, Daniel P. Howrigan, Yadi Zhou, Feixiong Cheng, Elmo Saarentaus +86 more

Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

Biological Psychiatry Global Open Science(2025)10.1016/j.bpsgos.2025.100604

Top 100%

0DataRank

Top 100%0 citations

Costin Leu, Yen‐Chen Anne Feng, David Burstein, Sanan Venkatesh, Rebecca Birnbaum +14 more

Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population

PLoS ONE(2020)10.1371/journal.pone.0232292

N/A

0DataRank · unranked

28 citations

Tom G. Richardson, Tobias Kaufmann, Dennis van der Meer, Ole A. Andreassen, Lars T. Westlye +4 more

Common molecular mechanisms ofSLC6A1variant-mediated neurodevelopmental disorders in astrocytes and neurons

Brain(2021)10.1093/brain/awab207

N/A

0DataRank · unranked

75 citations

Sarah Poliquin, Kathryn Rigsby, Anuj Rastogi, Wangzhen Shen, Alejandra I. Romero-Morales +9 more

ATP1A3-Related Disorders: An Ever-Expanding Clinical Spectrum

Frontiers in Neurology(2021)10.3389/fneur.2021.637890

N/A

0DataRank · unranked

70 citations

Ignácio F. Mata, Tobias Brünger, Dennis Lal, Hubert H. Fernandez, Philippe A. Salles

Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals

The American Journal of Human Genetics(2021)10.1016/j.ajhg.2021.04.009

N/A

0DataRank · unranked

60 citations

Gundula Povysil, Ryan S. Dhindsa, Kate E. Stanley, Andrew S. Allen, Yen‐Chen Anne Feng +95 more

Dennis Lal

Indexed papers

Top data-sharing exemplar

Papers