Emily E. Scott

Also affiliated with Barts Health NHS Trust, London Cancer, University Alliance

Pharmacology, Toxicology and PharmaceuticsMedicineComputer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 23 papers. Top paper: “Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability”.

Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability

Journal of Biological Chemistry(2020)10.1074/jbc.ra119.010727

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1.1DataRank · unranked

31 citations

Kurt L. Harris, Elizabeth M. J. Gillam, Emily E. Scott, Aaron G. Bart

Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine N-Methyltransferase Possessing Low Nanomolar Affinity at Both Substrate Binding Domains1

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c01475

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0DataRank · unranked

4 citations

Aaron G. Bart, Qian Wu, Kevin R. Criscione, Michael J. McLeish, Emily E. Scott +2 more

Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1

UNC Libraries(2020)10.17615/rsha-ay77

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0DataRank · unranked

0 citations

Emily E. Scott, Elyse M. Petrunak, Steven A. Rogers, Jeffrey Aubé

Cytochrome P450 Binding and Bioactivation of Tumor-Targeted Duocarmycin Agents

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000642

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0DataRank · unranked

13 citations

Goreti Ribeiro Morais, V.R. Vangala, Paul M. Loadman, Klaus Pors, Emily E. Scott +1 more

Structure and Function of Human Cytochrome P450 8B1

The FASEB Journal(2021)10.1096/fasebj.2021.35.s1.05037

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0DataRank · unranked

2 citations

Emily E. Scott, Jinghan Liu

The structure and characterization of human cytochrome P450 8B1 supports future drug design for nonalcoholic fatty liver disease and diabetes

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102344

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0DataRank · unranked

24 citations

Heather A. Carlson, Emily E. Scott, Jinghan Liu

Redox partner adrenodoxin alters cytochrome P450 11B1 ligand binding and inhibition

Journal of Inorganic Biochemistry(2022)10.1016/j.jinorgbio.2022.111934

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0DataRank · unranked

14 citations

Simone Brixius‐Anderko, Emily E. Scott, Cara L. Loomis

Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond

Drug Metabolism and Disposition(2022)10.1124/dmd.122.001109

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0DataRank · unranked

7 citations

Jeffrey Stevens, Grażyna D. Szklarz, Emily E. Scott, Santosh Kumar, Manish B. Shah +2 more

Profiling the Cytochrome P450 2J2 Active Site

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5384

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0DataRank · unranked

0 citations

Richard D. Smith, Heather A. Carlson, Emily E. Scott, Nicole Motl

Steroid‐Derived Isonitriles are Potent Cytochrome P450 Ligands that Should Enable Solution NMR as a Structural Technique to Probe P450 Dynamics

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5823

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0DataRank · unranked

0 citations

Thomas C. Pochapsky, Emily E. Scott, Alaina M. Richard

Protein/protein interactions in the human cytochrome P450 system

The FASEB Journal(2022)10.1096/fasebj.2022.36.s1.r5879

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0DataRank · unranked

0 citations

Emily E. Scott, Sarah D. Burris‐Hiday

Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.102999

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0DataRank · unranked

22 citations

Aaron G. Bart, Hwei‐Ming Peng, Richard J. Auchus, Emily E. Scott, Elyse M. Petrunak

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105112

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0DataRank · unranked

18 citations

Emily E. Scott, Sarah D. Burris‐Hiday

Pyridine-containing substrate analogs are restricted from accessing the human cytochrome P450 8B1 active site by tryptophan 281

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.103032

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0DataRank · unranked

6 citations

Samuel D. Offei, Francis K. Yoshimoto, Emily E. Scott, Jinghan Liu

Generation of human steroidogenic cytochrome P450 enzymes for structural and functional characterization

Methods in enzymology on CD-ROM/Methods in enzymology(2023)10.1016/bs.mie.2023.05.010

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0DataRank · unranked

6 citations

Cara L. Loomis, Alaina M. Richard, Emily E. Scott, Sarah D. Burris‐Hiday

Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104993

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0DataRank · unranked

5 citations

Sylvie E. Kandel, Jed N. Lampe, Emily E. Scott, Jinghan Liu

Selective steroidogenic cytochrome P450 haem iron ligation by steroid-derived isonitriles

Communications Chemistry(2023)10.1038/s42004-023-00994-3

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0DataRank · unranked

1 citations

Nathan R. Wong, Kurt L. Harris, Reethy Sundar, Emily E. Scott, Thomas C. Pochapsky +1 more

Development of a high throughput cytochrome P450 ligand-binding assay

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.107799

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0DataRank · unranked

5 citations

Emily E. Scott, Elyse K Frydendall

Adrenodoxin allosterically alters human cytochrome P450 11B enzymes to accelerate substrate binding and decelerate release

RSC Chemical Biology(2024)10.1039/d4cb00015c

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0DataRank · unranked

8 citations

Sang‐Choul Im, Emily E. Scott, Cara L. Loomis

Mass spectrometry footprinting reveals microsomal CYP2A6 structural changes induced by interaction with its reductase flavin mononucleotide domain

Drug Metabolism and Disposition(2025)10.1016/j.dmd.2025.100210

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0DataRank · unranked

2 citations

Sarah D. Burris‐Hiday, Don L. Rempel, Michael L. Gross, Emily E. Scott, Mengqi Chai

Redox partner adrenodoxin induces substrate binding to steroidogenic cytochrome P450 11B2 and 11A1 by promoting a conformational change

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110792

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0DataRank · unranked

1 citations

Michelle Redhair, Sang‐Choul Im, Emily E. Scott, Cara L. Loomis

Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents

International Journal of Molecular Sciences(2020)10.3390/ijms21144868

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0DataRank · unranked

11 citations

Oksana Rogova, Kasper Langebjerg Andersen, Rahul Yadav, Simone Brixius‐Anderko, Emily E. Scott +4 more

Cytochrome P450 2W1: Identification of new inhibitors, active site ligands, and pharmacophores

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110529

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0DataRank · unranked

0 citations

Emily E. Scott, Elyse K Frydendall