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Cytochrome P450 2W1: Identification of new inhibitors, active site ligands, and pharmacophores

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110529Source: DataRank Database

Cytochrome P450 2W1: Identification of new inhibitors, active site ligands, and pharmacophores is a research paper published in Journal of Biological Chemistry (2025). On theSindex it has a DataRank of 0.

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Open Access0 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)Impact (FWCI 0.00)OA: goldTopics (24)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (2)

Emily E. Scott ORCID,Elyse K Frydendall

Live enrichment

PubMed:40738188 PMC:PMC12446781 OpenAlex:https://openalex.org/W4412822900

NIH National Institute of General Medical Sciences

Grant: R37 GM076343

NIH National Institute of General Medical Sciences

Grant: T32 GM007767

University of Michigan

National Institutes of Health

FWCI

0.00

Citation Percentile

0.2%

goldLicense: cc-by-nc-nd

journalhttps://www.jbc.org/article/S0021-9258(25)02380-4/pdf

publisherhttps://www.jbc.org/article/S0021-9258(25)02380-4/pdf

publisherhttps://api.elsevier.com/content/article/PII:S0021925825023804?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0021925825023804?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.jbc.2025.110529

Fields of Study

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsInflammatory mediators and NSAID effects

MeSH Terms

Cytochrome P450 Family 2HumansIndolesLigandsProdrugsCatalytic DomainCytochrome P-450 Enzyme Inhibitors

Keywords

PharmacophoreChemistryProdrugActive siteCytochrome P450Ligand (biochemistry)StereochemistryEnzymeBiochemistryReceptorHigh-throughput screeningLigand bindingEnzyme inhibitionCytochrome P450 2W1

Sustainable Development Goals

SDG 0: Good health and well-being