Nadine Hempel

Also affiliated with UPMC Hillman Cancer Center, University of Pittsburgh Medical Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 36 papers. Top paper: “The native ORAI channel trio underlies the diversity of Ca2+ signaling events”.

The native ORAI channel trio underlies the diversity of Ca2+ signaling events

Nature Communications(2020)10.1038/s41467-020-16232-6

N/A

0.744DataRank · unranked

142 citations

Scott M. Emrich, Xuexin Zhang, Ping Xin, Martin Johnson, Adam J. Fike +7 more

Carcinoma-associated mesenchymal stem cells promote ovarian cancer heterogeneity and metastasis through mitochondrial transfer

Cell Reports(2024)10.1016/j.celrep.2024.114551

N/A

0.568DataRank · unranked

43 citations

Catherine A. Pressimone, Emma Dyer, Roja Baruwal, Geyon L. Garcia, Claudette M. St. Croix +9 more

Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression

EMBO Reports(2024)10.1038/s44319-024-00232-4

N/A

0.457DataRank · unranked

20 citations

Dong Hui Shin, Weihua Pan, Sierra R. White, Amal T. Elhaw, Yeon Kim +20 more

Aged and BRCA -Mutated Stromal Cells Drive Epithelial Cell Transformation

Cancer Discovery(2025)10.1158/2159-8290.cd-24-0805

N/A

0.345DataRank · unranked

9 citations

Taylor Orellana, Grace Gorecki, Leonard Frisbie, Roja Baruwal, Swathi Suresh +18 more

Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer

Cell Communication and Signaling(2024)10.1186/s12964-024-01496-y

N/A

0.312DataRank · unranked

7 citations

Laura M. Jenkins, Wade Barton, Asha Kumari, Carly L. Lancaster, Calen Raulerson +12 more

Extracellular signals induce dynamic ER remodeling through αTAT1-dependent microtubule acetylation

Neoplasia(2024)10.1016/j.neo.2024.101003

N/A

0.241DataRank · unranked

4 citations

Paola Cruz Flores, Julia Podgorski, Aaron Ramonett, Tasmia Ahmed, Nadine Hempel +8 more

De novo purine metabolism is a metabolic vulnerability of cancers with low p16 expression

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.15.549149

N/A

0.124DataRank · unranked

1 citations

Raquel Buj, Hui Wang, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja +11 more

Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

Cell Reports(2022)10.1016/j.celrep.2022.111066

N/A

0DataRank · unranked

63 citations

Mehri Monavarian, Kathleen O’Connell, Diego Altomare, Abigail Shelton, Shubham Mehta +12 more

PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance

Life Science Alliance(2022)10.26508/lsa.202201370

N/A

0DataRank · unranked

21 citations

Mehri Monavarian, Eduardo Listik, Abigail Shelton, Alex Seok Choi, Roel Quintens +6 more

Emerging perspectives on growth factor metabolic relationships in the ovarian cancer ascites environment

Seminars in Cancer Biology(2022)10.1016/j.semcancer.2022.03.004

N/A

0DataRank · unranked

25 citations

Amal T. Elhaw, Priscilla W. Tang, Zaineb Javed, Zainab Shonibare, Carly Bess Scalise +6 more

HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage-independence

Redox Biology(2022)10.1016/j.redox.2022.102329

N/A

0DataRank · unranked

23 citations

Priscilla W. Tang, Jaclyn E. Welles, Weihua Pan, Zaineb Javed, Amal T. Elhaw +4 more

Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers

Communications Biology(2022)10.1038/s42003-022-03495-6

N/A

0DataRank · unranked

18 citations

Shrikant Pradhan, Roohi Chaudhary, Eduardo Listik, Liz Quintero-Macías, Alex Seok Choi +10 more

A multiple-oscillator mechanism underlies antigen-induced Ca2+ oscillations in Jurkat T-cells

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105310

N/A

0DataRank · unranked

15 citations

Olivier Romito, Ahmed Emam Abdelnaby, Ping Xin, Trayambak Pathak, S. Weir +11 more

ATR promotes mTORC1 activity via de novo cholesterol synthesis

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.27.564195

N/A

0DataRank · unranked

4 citations

Alexandra N. Grumet, Richard Fang, Raquel Buj, Aidan R. Cole, Apoorva Uboveja +13 more

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.02.569652

N/A

0DataRank · unranked

1 citations

Raquel Buj, Apoorva Uboveja, Evan Levasseur, Hui Wang, Katarzyna M. Kedziora +33 more

Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 Mediator kinase inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.04.569970

N/A

0DataRank · unranked

1 citations

Resha Rajkarnikar, Emily Faith Page, Asha Kumari, Liz Quintero-Macías, Felipe Massicano +12 more

Data from Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

(2023)10.1158/0008-5472.c.6514022.v1

N/A

0DataRank · unranked

0 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more

Data from Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

(2023)10.1158/0008-5472.c.6514022

N/A

0DataRank · unranked

0 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more

Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.08.29.555364

N/A

0DataRank · unranked

0 citations

Laura M. Jenkins, Wade Barton, Asha Kumari, Carly L. Lancaster, Calen Raulerson +12 more

Stress response regulation of mRNA translation: Implications for antioxidant enzyme expression in cancer

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2317846121

N/A

0DataRank · unranked

20 citations

Scot R. Kimball, Elena Piskounova, Thomas J. Begley, Nadine Hempel, Yeon Kim

GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15

Gynecologic Oncology(2024)10.1016/j.ygyno.2024.02.004

N/A

0DataRank · unranked

13 citations

Ya-Yun Cheng, Shriya Kamlapurkar, Sierra R. White, Priscilla W. Tang, Amal T. Elhaw +6 more

De Novo Purine Metabolism is a Metabolic Vulnerability of Cancers with Low p16 Expression

Cancer Research Communications(2024)10.1158/2767-9764.crc-23-0450

N/A

0DataRank · unranked

9 citations

Raquel Buj, Hui Wang, Jiefei Wang, Aidan R. Cole, Apoorva Uboveja +14 more

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

Molecular Metabolism(2024)10.1016/j.molmet.2024.102031

N/A

0DataRank · unranked

6 citations

Emily Megill, Amanda J Chen, Afifa Farooqi, Naveen Kumar Tangudu, Apoorva Uboveja +6 more

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.06.578742

N/A

0DataRank · unranked

7 citations

Zhentai Huang, Raquel Buj, Amandine Amalric, Hui Wang, Naveen Kumar Tangudu +17 more

GPX3 supports ovarian cancer tumor progression in vivo and promotes expression of GDF15

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.24.577037

N/A

0DataRank · unranked

1 citations

Ya-Yun Cheng, Shriya Kamlapurkar, Sierra R. White, Priscilla W. Tang, Amal T. Elhaw +6 more

Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.12.603313

N/A

0DataRank · unranked

1 citations

Emily Megill, Amanda J Chen, Afifa Farooqi, Stacy McGonigal, Nadine Hempel +4 more

Crosstalk between calcium and reactive oxygen species signaling in cancer revisited

Cell Calcium(2025)10.1016/j.ceca.2025.103014

N/A

0DataRank · unranked

16 citations

J. Cory Benson, Priscilla W. Tang, Mohamed Trebak, Nadine Hempel, Trayambak Pathak

ATR promotes mTORC1 activity via de novo cholesterol synthesis

EMBO Reports(2025)10.1038/s44319-025-00451-3

N/A

0DataRank · unranked

2 citations

Alexandra N. Grumet, Richard Fang, Raquel Buj, Aidan R. Cole, Apoorva Uboveja +13 more

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2A Low tumors via increased macrophage phagocytosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.02.08.637227

N/A

0DataRank · unranked

3 citations

Aidan R. Cole, Jeff Danielson, Jimmy P. Xu, Drew E. Hurd, Akash Kishore +33 more

Mapping transcriptomic signatures downstream of mitochondrial superoxide dismutase SOD2 in OVCA433 multicellular aggregates

Advances in Redox Research(2025)10.1016/j.arres.2025.100141

N/A

0DataRank · unranked

0 citations

Priscilla W. Tang, Shriya Kamlapurkar, Sarah Al-Saad, Sneha Srinivasan, Danyang Li +4 more

Extracellular Glutathione Peroxidase GPx3 and Its Role in Cancer

Cancers(2020)10.3390/cancers12082197

N/A

0DataRank · unranked

240 citations

Beth L. Worley, Rébécca Phaëton, Nadine Hempel, Caroline Chang

Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling

Cell Reports(2021)10.1016/j.celrep.2021.108760

N/A

0DataRank · unranked

94 citations

Ryan E. Yoast, Ping Xin, Vikas Arige, Larry E. Wagner, Nadine Hempel +5 more

The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.101174

N/A

0DataRank · unranked

61 citations

Scott M. Emrich, Xuexin Zhang, Ping Xin, Vikas Arige, Trayambak Pathak +11 more

Regulation of Interorganellar Ca 2+ Transfer and NFAT Activation by the Mitochondrial Ca 2+ Uniporter

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.07.438854

N/A

0DataRank · unranked

1 citations

Scott M. Emrich, Xuexin Zhang, Ping Xin, Vikas Arige, Trayambak Pathak +10 more

HuR-dependent SOD2 protein synthesis is an early adaptation to anchorage independence

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.19.432010

N/A

0DataRank · unranked

0 citations

Jaclyn E Welles, Priscilla W Tang, Zaineb Javed, Amal T Elhaw, Karthikeyan Mythreye +3 more

Mitochondrial Calcium Uniporter Drives Metastasis and Confers a Targetable Cystine Dependency in Pancreatic Cancer

Cancer Research(2022)10.1158/0008-5472.can-21-3230

N/A

0DataRank · unranked

102 citations

Yunzhan Li, Zekun Li, Shengchen Lin, Hongwei Wang, Jianwei Sun +11 more