Mohamad‐Gabriel Alameh

Medicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 74 papers. Top paper: “Salp14 epitope-based mRNA vaccination induces early recognition of a tick bite”.

Salp14 epitope-based mRNA vaccination induces early recognition of a tick bite

Vaccine(2024)10.1016/j.vaccine.2024.126304

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0.109DataRank · unranked

1 citations

Balasubramanian Cibichakravarthy, Xiaotian Tang, Mohamad‐Gabriel Alameh, Garima Dwivedi, Drew Weissman +2 more

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

medRxiv(2020)10.1101/2020.07.22.20159905

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78 citations

Mohamad‐Gabriel Alameh, Thushan I. de Silva, Paul Collini, Hailey Hornsby, Rebecca Brown +20 more

An ionizable lipid toolbox for RNA delivery

Nature Communications(2021)10.1038/s41467-021-27493-0

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594 citations

Hanwen Zhang, Kamila Butowska, Kelsey L. Swingle, Mohamad‐Gabriel Alameh, Drew Weissman +2 more

Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device

Nano Letters(2021)10.1021/acs.nanolett.1c01353

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298 citations

Claude C. Warzecha, Sagar Yadavali, Rakan El‐Mayta, Mohamad‐Gabriel Alameh, Lili Wang +5 more

Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs

Molecular Therapy(2021)10.1016/j.ymthe.2021.06.004

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282 citations

Dorottya Laczkó, Hamna Shahnawaz, Hiromi Muramatsu, Ambika Natesan, Amir Yadegari +10 more

Ionizable lipid nanoparticles for in utero mRNA delivery

Science Advances(2021)10.1126/sciadv.aba1028

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223 citations

Meghana V. Kashyap, Margaret M. Billingsley, Brandon M. White, Mohamad‐Gabriel Alameh, Sourav K. Bose +8 more

Trivalent nucleoside-modified mRNA vaccine yields durable memory B cell protection against genital herpes in preclinical models

Journal of Clinical Investigation(2021)10.1172/jci152310

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35 citations

James J. Knox, Angela Desmond, Mohamad‐Gabriel Alameh, Brian T. Gaudette, John M. Lubinski +12 more

Combinatorial mRNA vaccination enhances protection against SARS-CoV-2 delta variant

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.08.471664

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2 citations

Jessica A. Plante, Yuejin Liang, Mohamad‐Gabriel Alameh, Jinyi Tang, Chaojie Zhong +15 more

A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes

Science(2022)10.1126/science.abm0271

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354 citations

Marcus J. Bolton, Valerie Le Sage, Naiqing Ye, Colleen Furey, Hiromi Muramatsu +13 more

Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment

Journal of the American Chemical Society(2022)10.1021/jacs.2c02706

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0DataRank · unranked

177 citations

Ningqiang Gong, Sarah J. Shepherd, Xinhong Xiong, Xueyang Liao, Xuexiang Han +14 more

Rational design of anti‐inflammatory lipid nanoparticles for mRNA delivery

Journal of Biomedical Materials Research Part A(2022)10.1002/jbm.a.37356

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74 citations

Xuexiang Han, Mohamad‐Gabriel Alameh, Sarah J. Shepherd, Marshall S. Padilla, Lulu Xue +4 more

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

npj Vaccines(2022)10.1038/s41541-022-00577-8

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56 citations

Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala, Garima Dwivedi +7 more

Modified E2 Glycoprotein of Hepatitis C Virus Enhances Proinflammatory Cytokines and Protective Immune Response

Journal of Virology(2022)10.1128/jvi.00523-22

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21 citations

Tapas Patra, Keith Meyer, Mohamad‐Gabriel Alameh, Erin K. Reagan, Drew Weissman +2 more

Antibodies to Crucial Epitopes on HSV-2 Glycoprotein D as a Guide to Dosing an mRNA Genital Herpes Vaccine

Viruses(2022)10.3390/v14030540

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18 citations

Sita Awasthi, Tina M. Cairns, Mohamad‐Gabriel Alameh, Bernard T. Fowler, Kevin P. Egan +5 more

SARS-CoV-2 mRNA-based vaccines in the Aicardi Goutières Syndrome

Molecular Genetics and Metabolism(2022)10.1016/j.ymgme.2022.10.001

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2 citations

Mohamad‐Gabriel Alameh, Sarah Woidill, Julia Hacker, Benjamin Davis, Guy Helman +13 more

Lipid nanoparticles delivering constitutively active STING mRNA as a novel anti-cancer therapeutic approach

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.08.475499

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8 citations

Mohamad‐Gabriel Alameh, June F. Yang, Jonathan R. Xu, Paulo J.C. Lin, Ying K. Tam +3 more

Mucosal immunity against SARS-CoV-2 variants of concern including Omicron following vaccination

medRxiv(2022)10.1101/2022.01.26.22269659

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3 citations

Cong Zeng, Thomas M Cox, Chaofan Li, Young Min Son, In Su Cheon +20 more

mRNA-LNP expressing PfCSP and Pfs25, two leading vaccine candidates targeting infection and transmission of Plasmodium falciparum

Research Square(2022)10.21203/rs.3.rs-1895368/v1

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0 citations

Clifford Hayashi, Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala +7 more

Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines

Nature Nanotechnology(2023)10.1038/s41565-023-01404-4

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237 citations

Mohamad‐Gabriel Alameh, Kamila Butowska, James J. Knox, Kendall A. Lundgreen, Majed Ghattas +11 more

Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis

Nature Communications(2023)10.1038/s41467-022-35637-z

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184 citations

Ningqiang Gong, Lulu Xue, Margaret M. Billingsley, Rakan El‐Mayta, Sarah J. Shepherd +4 more

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy

Journal of the American Chemical Society(2023)10.1021/jacs.2c12893

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141 citations

Hannah C. Safford, Hannah C. Geisler, Alex G. Hamilton, Ajay S. Thatte, Margaret M. Billingsley +8 more

Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2303567120

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125 citations

Xuexiang Han, Alvin J. Mukalel, Rakan El‐Mayta, Ajay S. Thatte, Jingyu Wu +8 more

Lipid nanoparticles (LNP) induce activation and maturation of antigen presenting cells in young and aged individuals

Communications Biology(2023)10.1038/s42003-023-04555-1

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114 citations

David Joyner, Nathan Mege, Gina Cusimano, Matthew R. Bell, Jennifer Marcy +9 more

Ionizable Lipid Nanoparticles with Integrated Immune Checkpoint Inhibition for mRNA CAR T Cell Engineering

Advanced Healthcare Materials(2023)10.1002/adhm.202301515

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95 citations

Kelsey L. Swingle, Ryann A. Joseph, David Mai, Ningqiang Gong, Margaret M. Billingsley +6 more

Ionizable Lipid Nanoparticles for Therapeutic Base Editing of Congenital Brain Disease

ACS Nano(2023)10.1021/acsnano.3c02268

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71 citations

Sourav K. Bose, Apeksha Dave, Brandon M. White, Cara Berkowitz, Valerie L. Luks +23 more

Systematic development of ionizable lipid nanoparticles for placental mRNA delivery using a design of experiments approach

Bioactive Materials(2023)10.1016/j.bioactmat.2023.11.014

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49 citations

Katherine M. Nelson, Samuel Hofbauer, Tara Vijayakumar, Mohamad‐Gabriel Alameh, Drew Weissman +4 more

Rapid and definitive treatment of phenylketonuria in variant-humanized mice with corrective editing

Nature Communications(2023)10.1038/s41467-023-39246-2

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48 citations

Manuel Carrasco, Ping Qü, William H. Peranteau, Rebecca C. Ahrens‐Nicklas, Kiran Musunuru +3 more

Orthogonal Design of Experiments for Engineering of Lipid Nanoparticles for mRNA Delivery to the Placenta

Small(2023)10.1002/smll.202303568

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37 citations

Kelsey L. Swingle, Hannah C. Geisler, Alex G. Hamilton, Ajay S. Thatte, Aditi A. Ghalsasi +5 more

A base editing strategy using mRNA-LNPs for in vivo correction of the most frequent phenylketonuria variant

Human Genetics and Genomics Advances(2023)10.1016/j.xhgg.2023.100253

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24 citations

Madelynn N. Whittaker, Hooda Said, Garima Dwivedi, Ping Qü, Kiran Musunuru +4 more

Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes

Arteriosclerosis Thrombosis and Vascular Biology(2023)10.1161/atvbaha.123.319748

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16 citations

Lauren Testa, Aidan Quigley, Ishaan Jindal, Saúl V. Cortez-Alvarado, Ping Qü +5 more

Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.30.538854

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5 citations

Naiqing Ye, Lisa Kercher, Jennifer DeBeauchamp, Jeri Carol Crumpton, Trushar Jeevan +10 more

Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.17.541156

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2 citations

Lauren Testa, Aidan Quigley, Ishaan Jindal, Saúl V. Cortez-Alvarado, Ping Qü +5 more

High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models

Nature Communications(2024)10.1038/s41467-024-45422-9

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126 citations

Alex G. Hamilton, Gan Zhao, Zebin Xiao, Rakan El‐Mayta, Xuexiang Han +13 more

Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia

Nature(2024)10.1038/s41586-024-08291-2

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105 citations

Alex G. Hamilton, Hannah C. Safford, Hannah C. Geisler, Ajay S. Thatte, Rohan Palanki +10 more

Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery

Nature Nanotechnology(2024)10.1038/s41565-024-01747-6

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92 citations

Gan Zhao, Ningqiang Gong, Xuexiang Han, Sarah J. Shepherd, Xinhong Xiong +20 more

Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke

Molecular Therapy(2024)10.1016/j.ymthe.2024.03.004

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85 citations

Patrick M. Glassman, Vladimir V. Shuvaev, Sahily Reyes‐Esteves, Hélène C. Descamps, Raisa Y. Kiseleva +22 more

Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo

Nature Chemistry(2024)10.1038/s41557-024-01557-2

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85 citations

Mohamad‐Gabriel Alameh, Ningqiang Gong, Lulu Xue, Majed Ghattas, Goutham Bojja +12 more

A multivalent mRNA-LNP vaccine protects against Clostridioides difficile infection

Science(2024)10.1126/science.adn4955

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75 citations

Alexa Semon, Nile U. Bayard, Yi‐Gen Pan, Garima Dwivedi, James J. Knox +24 more

Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus

Nature Communications(2024)10.1038/s41467-024-48555-z

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0DataRank · unranked

74 citations

Gabrielle Scher, Naiqing Ye, Lisa Kercher, Jennifer DeBeauchamp, Jeri Carol Crumpton +12 more

Antigen Presenting Cell Mimetic Lipid Nanoparticles for Rapid mRNA CAR T Cell Cancer Immunotherapy

Advanced Materials(2024)10.1002/adma.202313226

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73 citations

Marshall S. Padilla, Ningqiang Gong, Margaret M. Billingsley, Xuexiang Han, Maria Merolle +12 more

In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors

Nature Communications(2024)10.1038/s41467-024-45537-z

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69 citations

Junchao Xu, Ying Xu, Mohamad‐Gabriel Alameh, Lulu Xue, Ningqiang Gong +9 more

Tumour-derived small extracellular vesicles act as a barrier to therapeutic nanoparticle delivery

Nature Materials(2024)10.1038/s41563-024-01961-6

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60 citations

Wenqun Zhong, Mohamad‐Gabriel Alameh, Xuexiang Han, Lulu Xue, Rakan El‐Mayta +15 more

TGF-βR2 signaling coordinates pulmonary vascular repair after viral injury in mice and human tissue

Science Translational Medicine(2024)10.1126/scitranslmed.adg6229

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43 citations

Lulu Xue, Aaron I. Weiner, Ningqiang Gong, Stephanie Adams‐Tzivelekidis, Joanna Wong +16 more

In utero delivery of targeted ionizable lipid nanoparticles facilitates in vivo gene editing of hematopoietic stem cells

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2400783121

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41 citations

John S. Riley, Sourav K. Bose, Valerie L. Luks, Apeksha Dave, Nicole J. Kus +20 more

Improved influenza vaccine responses after expression of multiple viral glycoproteins from a single mRNA

Nature Communications(2024)10.1038/s41467-024-52940-z

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25 citations

Kaitlyn N. Burke, Rachel L. Spreng, Andrew N. Macintyre, Ying K. Tam, Mohamad‐Gabriel Alameh +3 more

Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants

npj Vaccines(2024)10.1038/s41541-024-00957-2

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10 citations

Jessica A. Plante, Srinivasa Reddy Bonam, Grace Rafael, Yuejin Liang, Nicholas C. Hazell +9 more

mRNA lipid nanoparticles expressing cell-surface cleavage independent HIV Env trimers elicit autologous tier-2 neutralizing antibodies

Frontiers in Immunology(2024)10.3389/fimmu.2024.1426232

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12 citations

Mehrdad Alirezaei, Yu Feng, Mohamad‐Gabriel Alameh, Wen-Hsin Lee, Sabyasachi Baboo +13 more

Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice

Vaccines(2024)10.3390/vaccines12050543

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10 citations

Nicholas C. Hazell, Mano Joseph Mathew, Yuejin Liang, Xuxiang Zhang, Zhi Wei +4 more

Comparison of the immunogenicity of mRNA-encoded and protein HIV-1 Env–ferritin nanoparticle designs

Journal of Virology(2024)10.1128/jvi.00137-24

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7 citations

Jill Whitley, Diana Martik, Laura L. Sutherland, Amanda Newman, Maggie Barr +24 more

Evaluation of mRNA-LNP and adjuvanted protein SARS-CoV-2 vaccines in a maternal antibody mouse model

npj Vaccines(2024)10.1038/s41541-024-00901-4

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7 citations

Elizabeth M. Drapeau, Mohamad‐Gabriel Alameh, Reihaneh Hosseinzadeh, Drew Weissman, Scott E. Hensley +1 more

mRNA vaccination of rabbits alters the fecundity, but not the attachment, of adult Ixodes scapularis

Scientific Reports(2024)10.1038/s41598-023-50389-6

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6 citations

Yingjun Cui, Geoffrey E. Lynn, Kathleen DePonte, Emily Mesquita, Hiromi Muramatsu +7 more

Immunization with PfGBP130 generates antibodies that inhibit RBC invasion by P. falciparum parasites

Frontiers in Immunology(2024)10.3389/fimmu.2024.1350560

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3 citations

Ahmad Rushdi Shakri, Sunthorn Pond‐Tor, Anup Jnawali, Tanbir Najrana, Haiwei Wu +9 more

Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.22.590531

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3 citations

Lauren C. Testa, Dominique L. Brooks, Aidan Quigley, Hooda Said, Garima Dwivedi +12 more

Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants

Research Square(2024)10.21203/rs.3.rs-4189618/v1

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0 citations

Renee L. Hajnik, Jessica A. Plante, Srinivasa Reddy Bonam, Grace Rafael, Yuejin Liang +8 more

Immature dendritic cell-targeting mRNA vaccine expressing PfCSP enhances protective immune responses against Plasmodium liver infection

Research Square(2024)10.21203/rs.3.rs-4656309/v1

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0 citations

Sean Yanik, Varsha Venkatesh, James T. Gordy, Mohamad‐Gabriel Alameh, Jacob Meza +9 more

Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease

New England Journal of Medicine(2025)10.1056/nejmoa2504747

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294 citations

Sarah Grandinette, Xiao Wang, Taylor R. Hudson, Kevin Briseno, Anne Marie Berry +40 more

Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen

Journal of the American Chemical Society(2025)10.1021/jacs.4c10265

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34 citations

Xinhong Xiong, Gan Zhao, William A. Molina Arocho, Rohan Palanki, Zebin Xiao +14 more

Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo

Proceedings of the National Academy of Sciences(2025)10.1073/pnas.2409266122

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12 citations

Ying K. Tam, Benjamin W. Lee, Jacob W. Myerson, D. Alan Herbst, Raisa Y. Kiseleva +27 more

iDC-targeting PfCSP mRNA vaccine confers superior protection against Plasmodium compared to conventional mRNA

npj Vaccines(2025)10.1038/s41541-025-01089-x

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11 citations

Varsha Venkatesh, James T. Gordy, Mohamad‐Gabriel Alameh, Jacob Meza, Yangchen Li +9 more

Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs

Nature Biomedical Engineering(2025)10.1038/s41551-025-01545-y

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9 citations

Lauren Testa, Aidan Quigley, Dominique L. Brooks, Sarah Grandinette, Hooda Said +14 more

Allergen-specific mRNA–lipid nanoparticle therapy for prevention and treatment of experimental allergy in mice

Journal of Clinical Investigation(2025)10.1172/jci194080

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7 citations

Michael Kotliar, Andrea M. Klingler, Mark Rochman, Mohamad‐Gabriel Alameh, Jilian R. Melamed +10 more

Automated and Parallelized Microfluidic Generation of Large and Precisely Defined Lipid Nanoparticle Libraries

ACS Nano(2025)10.1021/acsnano.5c15613

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6 citations

Sarah J. Shepherd, Gregory Datto, Rakan El‐Mayta, Taigh Anderson, Isabel B. Navarro +11 more

Monitoring mRNA vaccine antigen expression in vivo using PET/CT

Nature Communications(2025)10.1038/s41467-025-57446-w

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17 citations

Garima Dwivedi, Yi‐Gen Pan, Catherine Hou, Jean M. Etersque, Hooda Said +11 more

Tick feeding or vaccination with tick antigens elicits immunity to the Ixodes scapularis exoproteome in guinea pigs and humans

Science Translational Medicine(2025)10.1126/scitranslmed.ads9207

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7 citations

Yingjun Cui, Sam R. Telford, Alejandro Marín-López, Keith Calloway, Yile Dai +16 more

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

Advanced Therapeutics(2025)10.1002/adtp.202500148

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7 citations

Luisa A. Fink, Rachel E. Young, Tara Vijayakumar, Katherine M. Nelson, Nia Bellopede +5 more

IL-12 mRNA-LNP promotes dermal resident memory CD4+ T cell development

npj Vaccines(2025)10.1038/s41541-025-01213-x

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6 citations

Claudia Gonzalez-Lombana, Mohamad‐Gabriel Alameh, Laís Amorim Sacramento, Zhirong Mou, Anthony T. Phan +7 more

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity

Mucosal Immunology(2025)10.1016/j.mucimm.2025.08.004

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4 citations

Jennifer Londregan, Joshua E. Denny, Ellie N Hulit, Nontokozo V. Mdluli, F. Christopher Peritore‐Galve +6 more

Systemic mRNA-LNP administration in fetuses improves survival in a mouse model of spinal muscular atrophy

Molecular Therapy — Methods & Clinical Development(2025)10.1016/j.omtm.2025.101599

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4 citations

Nicole J. Kus, Rosa Choi, Hooda Said, Ana Maria Dumitru, James Bauer +7 more

An influenza HA mRNA-LNP vaccine induces potent responses in newborn nonhuman primates that enhance protection from challenge

npj Vaccines(2025)10.1038/s41541-025-01317-4

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1 citations

Beth C. Holbrook, Kali F. Crofts, Mohamad‐Gabriel Alameh, Benjamin Davis, David L. Caudell +3 more

Clostridioides difficile toxin A and toxin B inhibit toxin-specific adaptive immune responses through glucosyltransferase-dependent activity

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.30.667646

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0 citations

Jennifer Londregan, Joshua E. Denny, Ellie N Hulit, Nontokozo V. Mdluli, F. Christopher Peritore‐Galve +6 more

Liver-directed base editing of ABCC6 prevents ectopic calcification in a variant-humanized mouse model of pseudoxanthoma elasticum

Molecular Therapy — Nucleic Acids(2025)10.1016/j.omtn.2025.102769

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0 citations

Dorcas Obiri‐Yeboah, Hooda Said, Ping Qü, Michael A. Levine, Mohamad‐Gabriel Alameh +4 more

The effect of Natural Killer cell depletion and inhibition on mRNA vaccine immunogenicity and reactogenicity 3829

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1585

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0 citations

Emilie Goguet, Hannah Haines-Hull, Stephen K. Anderson, Mohamad‐Gabriel Alameh, Edward Mitre +1 more

D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization

Cell Host & Microbe(2020)10.1016/j.chom.2020.11.012

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354 citations

Mohamad‐Gabriel Alameh, Thushan I. de Silva, Paul Collini, Hailey Hornsby, Rebecca Brown +20 more

Clostridioides difficile toxin B inhibits antigen-specific adaptive immune responses through glucosyltransferase-dependent activity 3906

The Journal of Immunology(2025)10.1093/jimmun/vkaf283.1653

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0 citations

Jennifer Londregan, Joshua E. Denny, F. Christopher Peritore, Mohamad‐Gabriel Alameh, Joseph P. Zackular +3 more