Ken Yamada

University of Massachusetts Chan Medical School

Also affiliated with UMass Memorial Medical Center

EngineeringBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 21 papers. Top paper: “Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection”.

Divalent siRNAs are bioavailable in the lung and efficiently block SARS-CoV-2 infection

Proceedings of the National Academy of Sciences(2023)10.1073/pnas.2219523120

N/A

1.2DataRank · unranked

48 citations

Minwook Shin, Ching‐Wen Chang, Daniel O’Reilly, Annabelle Biscans, Ken Yamada +41 more

Phosphatidylcholine head group chemistry alters the extrahepatic accumulation of lipid-conjugated siRNA

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102230

N/A

0.269DataRank · unranked

5 citations

Takahiro Nakamura, Minwook Shin, Qi Tang, Vyankat A. Sontakke, Jillian Caiazzi +4 more

Formamide significantly enhances the efficiency of chemical adenylation of RNA sequencing ligation adaptors

RNA(2023)10.1261/rna.079521.122

N/A

0.104DataRank · unranked

1 citations

Adam K. Hedger, Ken Yamada, Jonathan K. Watts, Anastasia Khvorova, Samuel Hildebrand

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.05.26.542506

N/A

0DataRank · unranked

7 citations

Vignesh Hariharan, Jillian Caiazzi, Rachael Miller, Chantal Furguson, Ellen Sapp +18 more

Extended Nucleic Acid (exNA): A Novel, Biologically Compatible Backbone that Significantly Enhances Oligonucleotide Efficacy in vivo

Research Square(2023)10.21203/rs.3.rs-2987323/v1

N/A

0DataRank · unranked

4 citations

Jillian Caiazzi, Rachael Miller, Chantal Ferguson, Ellen Sapp, Hassan Fakih +18 more

A programmable dual-targeting di-valent siRNA scaffold supports potent multi-gene modulation in the central nervous system

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.19.572404

N/A

0DataRank · unranked

4 citations

Qi Tang, Sam Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

A programmable dual-targeting siRNA scaffold supports potent two-gene modulation in the central nervous system

Nucleic Acids Research(2024)10.1093/nar/gkae368

N/A

0DataRank · unranked

26 citations

Qi Tang, Samuel Hildebrand, Ashley Summers, Ellen Sapp, Dimas Echeverria +11 more

Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102359

N/A

0DataRank · unranked

20 citations

Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato +10 more

Identification of selective and non-selective C9ORF72 targeting in vivo active siRNAs

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102291

N/A

0DataRank · unranked

9 citations

Zachary Kennedy, Bruno M.D.C. Godinho, Ashley Summers, Alexandra Weiss, Dimas Echeverria +10 more

mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo

Nucleic Acid Therapeutics(2024)10.1089/nat.2024.0027

N/A

0DataRank · unranked

8 citations

Daniel O’Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette +8 more

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.20.599943

N/A

0DataRank · unranked

6 citations

James W. Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal Ferguson, Elif O. Dogan +18 more

mRNA nuclear clustering leads to a difference in mutant huntingtin mRNA and protein silencing by siRNAs in vivo

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.24.590997

N/A

0DataRank · unranked

2 citations

Daniel O’Reilly, Rachael Miller, Ellen Sapp, Ashley Summers, Joseph Paquette +8 more

Preventing acute neurotoxicity of CNS therapeutic oligonucleotides with the addition of Ca2+ and Mg2+ in the formulation

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.06.597639

N/A

0DataRank · unranked

1 citations

Joseph Paquette, Alexandra Barker, Ellen Sapp, Nicholas McHugh, Brianna Bramato +10 more

Systematic analysis of siRNA and mRNA features impacting fully chemically modified siRNA efficacy

Nucleic Acids Research(2025)10.1093/nar/gkaf479

N/A

0DataRank · unranked

15 citations

Samuel Hildebrand, Hannah J. MacMillan, Kathryn Monopoli, Julianna Buchwald, Jacquelyn Sousa +20 more

RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice

Molecular Therapy(2025)10.1016/j.ymthe.2025.05.010

N/A

0DataRank · unranked

8 citations

James W. Gilbert, Iris Valeria Rivera Flores, Jillian Belgrad, Chantal Ferguson, Elif O. Dogan +19 more

Mutant huntingtin exon 1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MutS Homolog 3 silencing and aggregation

Brain Communications(2025)10.1093/braincomms/fcaf314

N/A

0DataRank · unranked

5 citations

Adel Boudi, Andrew Iwanowicz, Jillian Belgrad, Rachael Miller, R. Meldrum Robertson +11 more

Potent and durable gene modulation in heart and muscle with chemically defined lipophilic siRNAs

Nucleic Acids Research(2025)10.1093/nar/gkaf1374

N/A

0DataRank · unranked

1 citations

Clemens Lochmann, Rosemary Gagnon, Ashley Summers, Jillian Caiazzi, Julianna Buchwald +15 more

Structurally constrained phosphonate internucleotide linkage impacts oligonucleotide-enzyme interaction, and modulates siRNA activity and allele specificity

Nucleic Acids Research(2021)10.1093/nar/gkab1126

N/A

0DataRank · unranked

20 citations

Samuel Hildebrand, Sarah M. Davis, Rachael Miller, Faith Conroy, Ellen Sapp +10 more

A Therapeutic Small-Interfering RNA Potentiates Janus Kinase 1 Modulation for the Treatment of Dog Inflammatory Diseases

ACS Pharmacology & Translational Science(2025)10.1021/acsptsci.4c00594

N/A

0DataRank · unranked

0 citations

Hassan H. Fakih, Katherine Y. Gross, Sarah J. Winter, Brianna Bramato, Ümmügülsüm Yıldız-Altay +13 more

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in Huntington’s disease models

Nature Communications(2022)10.1038/s41467-022-33061-x

N/A

0DataRank · unranked

49 citations

Rachael Miller, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Bruno M.D.C. Godinho +12 more

Chemical engineering of therapeutic siRNAs for allele-specific gene silencing in vivo in CNS

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.06.29.498088

N/A

0DataRank · unranked

0 citations

Rachael Miller, Julia F. Alterman, Matthew Hassler, Dimas Echeverria, Bruno M.D.C. Godinho +12 more