Lorena Orozco

Also affiliated with National Institute of Genomic Medicine, Statistical Research (United States)

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

24.2Author DataRank

Indexed papers

7in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 7 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Analysis of protein-coding genetic variation in 60,706 humans

Nature(2016)10.1038/nature19057

Top 1%

13.0DataRank

Top 1%10410 citations

Monkol Lek, Konrad J. Karczewski, Eric V. Minikel, Kaitlin E. Samocha, Iain Mathieson +76 more

Papers

Driven by 24 papers — median percentile 96. Top paper: “Analysis of protein-coding genetic variation in 60,706 humans”.

Analysis of protein-coding genetic variation in 60,706 humans

Nature(2016)10.1038/nature19057

Top 1%

13.0DataRank

Top 1%10410 citations

Monkol Lek, Konrad J. Karczewski, Eric V. Minikel, Kaitlin E. Samocha, Iain Mathieson +76 more

A structural variation reference for medical and population genetics

Nature(2020)10.1038/s41586-020-2287-8

Top 3%

6.7DataRank

Top 3%1180 citations

Harrison Brand, Konrad J. Karczewski, Xuefang Zhao, Jessica Alföldi, Laurent C. Francioli +201 more

Evidence that duplications of 22q11.2 protect against schizophrenia

Molecular Psychiatry(2013)10.1038/mp.2013.156

N/A

5.8DataRank · unranked

188 citations

James T.R. Walters, J T R Walters, K D Chambert, Dragan M. Švrakić, J Szatkiewicz +53 more

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

Nature Communications(2020)10.1038/s41467-019-12438-5

N/A

5.6DataRank · unranked

143 citations

James Zou, Beryl B. Cummings, Jessica Alföldi, Laurent C. Francioli, Laura D. Gauthier +174 more

Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

Nature Communications(2020)10.1038/s41467-019-10717-9

N/A

5.2DataRank · unranked

191 citations

Konrad J. Karczewski, Xiaolei Zhang, Sonia Chothani, Miriam J. Smith, D. Gareth Evans +181 more

The effect of LRRK2 loss-of-function variants in humans

Nature Medicine(2020)10.1038/s41591-020-0893-5

N/A

4.9DataRank · unranked

114 citations

Irina M. Armean, Aaron Kleinman, Jamie L. Marshall, Eric V. Minikel, Julia K. Goodrich +214 more

Reconstruction of ancient microbial genomes from the human gut

Nature(2021)10.1038/s41586-021-03532-0

Top 5%

4.3DataRank

Top 5%249 citations

Zhen Yang, Maxime Borry, Alexander Hübner, Kun D. Huang, Braden Tierney +23 more

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

Nature Communications(2021)10.1038/s41467-021-23556-4

N/A

2.7DataRank · unranked

110 citations

Moriel Singer‐Berk, Rachel G. Son, Abigail Sveden, Jordan C. Wood, Eleina England +95 more

The mutational constraint spectrum quantified from variation in 141,456 humans

Nature(2020)10.1038/s41586-020-2308-7

N/A

1.4DataRank · unranked

9958 citations

Laurent C. Francioli, Grace Tiao, Beryl B. Cummings, Jessica Alföldi, Qingbo S. Wang +187 more

De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia

Molecular Psychiatry(2011)10.1038/mp.2011.154

N/A

1.0DataRank · unranked

874 citations

A J Pocklington, D Ivanov, Samuel A. Rose, Andrew McQuillin, Hywel Williams +46 more

Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia

Human Molecular Genetics(2007)10.1093/hmg/ddm323

N/A

0.892DataRank · unranked

381 citations

D. Gumus, Ivan Nikolov, L. Georgieva, M. Sari, F. Erdogan +13 more

Association of a Low-Frequency Variant inHNF1AWith Type 2 Diabetes in a Latino Population

JAMA(2014)10.1001/jama.2014.6511

N/A

0.842DataRank · unranked

273 citations

Ingvild Aukrust, Lise Bjørkhaug, Noël P. Burtt, Josep M. Mercader, Humberto García-Ortiz +45 more

Transcript expression-aware annotation improves rare variant interpretation

Nature(2020)10.1038/s41586-020-2329-2

N/A

0.796DataRank · unranked

201 citations

Konrad J. Karczewski, Ditte Demontis, Eleanor G. Seaby, Nicholas A. Watts, Moriel Singer-Berk +177 more

Evaluating drug targets through human loss-of-function genetic variation

Nature(2020)10.1038/s41586-020-2267-z

N/A

0.779DataRank · unranked

179 citations

Konrad J. Karczewski, Hilary C. Martin, Beryl B. Cummings, Nicola Whiffin, Daniel R. Rhodes +150 more

Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium

Human Genetics and Genomics Advances(2022)10.1016/j.xhgg.2022.100099

N/A

0.759DataRank · unranked

25 citations

Mariaelisa Graff, Victoria L. Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo +95 more

The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes

Diabetologia(2023)10.1007/s00125-023-05912-9

N/A

0.434DataRank · unranked

17 citations

Philip Schroeder, Ravi Mandla, Aaron J. Deutsch, Wanying Zhu, Lauren E. Petty +59 more

Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits - the Hispanic/Latino Anthropometry Consortium

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.27.445969

N/A

0.434DataRank · unranked

17 citations

Mariaelisa Graff, Victoria L. Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo +95 more

Clinical and neuroradiological spectrum of biallelic variants in NOTCH3

EBioMedicine(2024)10.1016/j.ebiom.2024.105297

N/A

0.385DataRank · unranked

12 citations

Cesar Alves, Aisha M. Al Shamsi, Gehad ElGhazali, Maha S. Zaki, Lorenzo Pinelli +46 more

The power of TOPMed imputation for the discovery of Latino enriched rare variants associated with type 2 diabetes

medRxiv(2022)10.1101/2022.09.30.22280535

N/A

0.269DataRank · unranked

5 citations

Philip Schroeder, Ravi Mandla, Aaron J. Deutsch, Wanying Zhu, Lauren E. Petty +57 more

Replication of Integrative Data Analysis for Adipose Tissue Dysfunction, Low-Grade Inflammation, Postprandial Responses and OMICs Signatures in Symptom-Free Adults

Biology(2021)10.3390/biology10121342

Top 60%

0.245DataRank

Top 60%3 citations

Ernesto Rodríguez-Ayala, Hugo Laviada‐Molina, Edna J. Nava‐González, Rocío A. Salinas-Osornio, Lorena Orozco +34 more

Amelogenesis imperfecta: Literature review.

Revista Estomatología(2015)10.25100/re.v23i1.2968

N/A

0.241DataRank · unranked

4 citations

Fabián Tobar-Tosse, Julio Osorio, Lorena Orozco, Freddy Moreno, Paula-Margarita Hurtado

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries

The Lancet Diabetes & Endocrinology(2026)10.1016/s2213-8587(25)00405-x

N/A

0.208DataRank · unranked

3 citations

Joohyun Kim, Ravi Mandla, Yingchang Lu, Ken Suzuki, Lauren E Petty +255 more

Generation of two induced pluripotent stem cell lines from patients suffering from pulmonary hypertension

Stem Cell Research(2023)10.1016/j.scr.2023.103218

N/A

0DataRank · unranked

1 citations

Lorena Orozco, Sophia Parmisano, James W.S. Jahng, Carlos Vera, Yan Zhuge +3 more

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes

medRxiv(2020)10.1101/2020.09.22.20195529

N/A

0DataRank · unranked

11 citations

Moriel Singer‐Berk, Rachel G. Son, Abigail Sveden, Jordan C. Wood, Eleina England +95 more

Lorena Orozco

Indexed papers

Top data-sharing exemplar

Papers