Charles E. Chalfant

United States Department of Veterans Affairs

Also affiliated with University of Virginia Medical Center, VA Central California Health Care System, University of Virginia Cancer Center, University of Virginia, Virginia Commonwealth University Medical Center

Biochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 30 papers. Top paper: “Lipid mediators and biomarkers associated with type 1 diabetes development”.

Lipid mediators and biomarkers associated with type 1 diabetes development

JCI Insight(2020)10.1172/jci.insight.138034

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0DataRank · unranked

30 citations

Daniel Stephenson, Robert N. Bone, Christopher L. Cardona, Margaret A. Park, Ying G. Tusing +9 more

Functional inhibition or genetic deletion of acid sphingomyelinase bacteriostatically inhibits Anaplasma phagocytophilum infection in vivo

Pathogens and Disease(2020)10.1093/femspd/ftaa072

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6 citations

Jacob J. Gumpf, Chelsea L. Cockburn, Sarah Camus, Charles E. Chalfant, Pin‐Lan Li +2 more

Chronic hypoxia regulates Cytoplasmic Polyadenylation Element Binding Protein 2 alternative splicing to promote HIF1a translation

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.05.325290

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1 citations

Shaun C. Stevens, Anika N. Ali, Christina J. Moss, Sean P. Lund, Gina S. Nazario-Muñoz +5 more

Systemic Elevation of n-3 Polyunsaturated Fatty Acids (n-3-PUFA) Is Associated with Protection against Visual, Motor, and Emotional Deficits in Mice following Closed-Head Mild Traumatic Brain Injury

Molecular Neurobiology(2021)10.1007/s12035-021-02501-y

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22 citations

Haruka Takahashi, J. W. Cole, Nobel A. Del Mar, Chunyan Li, Daniel Stephenson +6 more

Alterations in β-Cell Sphingolipid Profile Associated with ER Stress and iPLA2β: Another Contributor to β-Cell Apoptosis in Type 1 Diabetes

Molecules(2021)10.3390/molecules26216361

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7 citations

Xiaoyong Lei, Suzanne E. Barbour, Akio Koizumi, Charles E. Chalfant, Sasanka Ramanadham +1 more

Sustained local inhibition of thrombin preserves renal microarchitecture and function after onset of acute kidney injury

Nanomedicine Nanotechnology Biology and Medicine(2021)10.1016/j.nano.2021.102449

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9 citations

Daniel Stephenson, Margaret K. Baldwin, Joseph P. Gaut, Charles E. Chalfant, Hua Pan +2 more

Evidence for Systemic Reactive Oxygen Species in UVB‐mediated Microvesicle Formation

Photochemistry and Photobiology(2021)10.1111/php.13494

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7 citations

Lea Christian, Benjamin N. Schmeusser, Langni Liu, Charles E. Chalfant, Daniel J. Stephensen +8 more

Purification of Cytosolic Phospholipase A2α C2-domain after Expression in Soluble Form in Escherichia coli

BIO-PROTOCOL(2021)10.21769/bioprotoc.3906

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1 citations

Yong‐Guang Gao, Dhirendra K. Simanshu, Daniel Stephenson, Ngoc Vu, Lucy Malinina +4 more

Ceramide Kinase Inhibition Drives Ferroptosis and Sensitivity to Cisplatin in Mutant KRAS Lung Cancer by Dysregulating VDAC-Mediated Mitochondria Function

Molecular Cancer Research(2022)10.1158/1541-7786.mcr-22-0085

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54 citations

Minjung Kim, Daniel Stephenson, H. Patrick MacKnight, Charles E. Chalfant, Ngoc Vu

Hydroxychloroquine Causes Early Inner Retinal Toxicity and Affects Autophagosome–Lysosomal Pathway and Sphingolipid Metabolism in the Retina

Molecular Neurobiology(2022)10.1007/s12035-022-02825-3

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25 citations

Hunter L. Porter, J. W. Cole, Hemang K. Pandya, Sandip K. Basu, Sufiya Khanam +6 more

Caspase 9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

Molecular Cancer Research(2022)10.1158/1541-7786.mcr-21-0905

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11 citations

Ngoc T. Vu, Xue Wang, Gamze B. Bulut, Min-Hsuan Wang, Cora Uram-Tuculescu +4 more

Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy

Journal of Lipid Research(2023)10.1016/j.jlr.2023.100377

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19 citations

H. Patrick MacKnight, L. Alexis Hoeferlin, Sonya L. Washington, Chelsea Sawyers, Kellie J. Archer +4 more

Skewing cPLA 2 α activity toward oxoeicosanoid production promotes neutrophil N2 polarization, wound healing, and the response to sepsis

Science Signaling(2023)10.1126/scisignal.add6527

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17 citations

Daniel Stephenson, H. Patrick MacKnight, Ngoc Vu, L. Alexis Hoeferlin, Minjung Kim +4 more

Lipids from ocular meibum and tears may serve as biomarkers for depression and post‐traumatic stress disorder

Clinical and Experimental Ophthalmology(2023)10.1111/ceo.14343

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7 citations

Amanda Prislovsky, Arianna Tovar, Elyana V. T. Locatelli, Elizabeth R. Felix, Daniel Stephenson +6 more

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia

Cancers(2023)10.3390/cancers15061883

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7 citations

Miki Kassai, James T. Hagen, P. Darrell Neufer, Mark Kester, David J. Feith +14 more

Fluoxetine restrains allergic inflammation by targeting an FcɛRI-ATP positive feedback loop in mast cells

Science Signaling(2023)10.1126/scisignal.abc9089

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3 citations

Marcela T Taruselli, Sydney Ann Kee, Jordan Dailey, Neha Pondicherry, Paula A. Gajewski-Kurdziel +15 more

Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.10.21.563437

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2 citations

Su‐Fern Tan, Todd E. Fox, Jeremy J.P. Shaw, Maansi Taori, Bethany J. Horton +10 more

Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia

UNC Libraries(2023)10.17615/n1yy-be39

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0 citations

Jeremy J.P. Shaw, Johnson Ung, Gemma Fabriàs, Miki Kassai, James T. Hagen +14 more

Role of Polyunsaturated Fatty Acids (PUFAs) and Eicosanoids on Dry Eye Symptoms and Signs

Biomolecules(2024)10.3390/biom14030376

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8 citations

Amanda Prislovsky, Daniel Stephenson, Charles E. Chalfant, Anat Galor, Nawajes Mandal +1 more

Sphingolipid biosynthetic inhibitor L-Cycloserine prevents oxidative-stress-mediated death in an in vitro model of photoreceptor-derived 661W cells

Experimental Eye Research(2024)10.1016/j.exer.2024.109852

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6 citations

Sandip K. Basu, Amanda Prislovsky, Koushik Mondal, Dejian Ma, Harry Kochat +5 more

Ceramide-1-phosphate is a regulator of Golgi structure and is co-opted by the obligate intracellular bacterial pathogen Anaplasma phagocytophilum

mBio(2024)10.1128/mbio.00299-24

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7 citations

Anika N. Ali, Daniel Stephenson, H. Patrick MacKnight, Kenneth D. Maus, Chelsea L. Cockburn +5 more

Sphingolipid changes in mouse brain and plasma after mild traumatic brain injury at the acute phases

Lipids in Health and Disease(2024)10.1186/s12944-024-02186-x

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7 citations

Nobel A. Del Mar, Ashlyn A. Gary, Richard C. Grambergs, Mohd. Yousuf, Faiza Tahia +6 more

RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer

Molecular Therapy — Nucleic Acids(2024)10.1016/j.omtn.2024.102412

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5 citations

H. Patrick MacKnight, Amy L. Lu, Charles E. Chalfant, Xiujie Xie

Inhibiting De Novo Biosynthesis of Ceramide by L-Cycloserine Can Prevent Light-Induced Retinal Degeneration in Albino BALB/c Mice

International Journal of Molecular Sciences(2024)10.3390/ijms252413389

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3 citations

Dejian Ma, Daniel Stephenson, Sandip K. Basu, Nobel A. Del Mar, Nataliya Lenchik +5 more

Selective Reduction of Ca2+-Independent Phospholipase A2β (iPLA2β)-Derived Lipid Signaling From Macrophages Mitigates Type 1 Diabetes Development

Diabetes(2024)10.2337/db23-0770

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1 citations

Tayleur D. White, Daniel Stephenson, Benjamin Stephenson, Ying Gai-Tusing, Paran Goel +7 more

Mouse Model of Nitrogen Mustard Ocular Surface Injury Characterization and Sphingolipid Signaling

International Journal of Molecular Sciences(2024)10.3390/ijms25020742

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2 citations

Amanda Prislovsky, Nataliya Lenchik, Daniel Stephenson, Rajesh Agarwal, Charles E. Chalfant +2 more

The role of 6-phosphogluconate dehydrogenase in vascular smooth muscle cell phenotypic switching and angioplasty-induced intimal hyperplasia

JVS Vascular Science(2024)10.1016/j.jvssci.2024.100214

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1 citations

Li Yin, Yitao Huang, Zain Husain Islam, Rohan Kanchetty, Campbell Johnston +6 more

Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia via a cytotoxic integrated stress response

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.06.657881

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0 citations

Su‐Fern Tan, Jeremy J.P. Shaw, Maansi Taori, Tess M. Deddens, Giovana da Costa Venancio +18 more

The long non-coding RNA, CyKILRb, augments oncogenic phenotypes via induction of PIK3R2 and activation of the PI 3 K/AKT axis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.13.682173

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0 citations

H. Patrick MacKnight, Amy L. Lu, Charles E. Chalfant, Xiujie Xie

Investigating the Eye as a Biomarker of Gulf War Illness: Sphingolipid and Eicosanoid Composition in Tears and Plasma

Biomolecules(2025)10.3390/biom15121716

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0DataRank · unranked

0 citations

Amanda Prislovsky, Loralei Ann Parchejo, Kim Cabrera, Andrew J. Nafziger, Daniel Stephenson +7 more